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M. tuberculosis H37Rv Rv1483 (fabG1)

annotation: 3-OXOACYL-
coordinates: 1673440 - 1674183
length: 247

VTATATEGAKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKGLFGVECDVTDSDAVDR
AFTAVEEHQGPVEVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGS
VSGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTRALDERIQQGALQFIPAKR
VGTPAEVAGVVSFLASEDASYISGAVIPVDGGMGMGH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1483fabG1-100% (247)3-OXOACYL-
M. tuberculosis H37RvRv1350fabG2e-4439.08% (238) 3-ketoacyl-(acyl-carrier-protein) reductase
M. tuberculosis H37RvRv0242cfabG6e-3031.97% (244) 3-ketoacyl-(acyl-carrier-protein) reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1519fabG11e-137100.00% (247) 3-oxoacyl-
M. gilvum PYR-GCKMflv_3658-1e-11785.77% (246) 3-oxoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG11e-9469.75% (238) 3-oxoacyl-
M. abscessus ATCC 19977MAB_2723c-3e-9369.79% (235) 3-oxoacyl-
M. marinum MMMAR_2289fabG11e-12692.28% (246) 3-oxoacyl-
M. avium 104MAV_3295fabG1e-11885.37% (246) 3-oxoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_3150fabG1e-11584.15% (246) 3-oxoacyl-(acyl-carrier-protein) reductase
M. thermoresistible (build 8)TH_3966-3e-8584.62% (182) PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase
M. ulcerans Agy99MUL_1491fabG11e-12691.87% (246) 3-oxoacyl-
M. vanbaalenii PYR-1Mvan_2752-1e-12188.21% (246) 3-oxoacyl-(acyl-carrier-protein) reductase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1483|M.tuberculosis_H37Rv         MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
Mb1519|M.bovis_AF2122/97            MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MMAR_2289|M.marinum_M               MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLAADGHRV
MUL_1491|M.ulcerans_Agy99           MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLATDGHRV
Mflv_3658|M.gilvum_PYR-GCK          MTSTEN---TAGESVAGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
Mvan_2752|M.vanbaalenii_PYR-1       MTLTENSAGTAGETGGGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MAV_3295|M.avium_104                MTDTATENTTESAADFGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MSMEG_3150|M.smegmatis_MC2_155      MTVTDNPADTAGEATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKV
TH_3966|M.thermoresistible__bu      --------VSPEAASPVQASHCSCAIRVSAAN------------------
MLBr_01807|M.leprae_Br4923          --MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRV
MAB_2723c|M.abscessus_ATCC_199      --MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKV
                                                        . . :: *:..*                  

Rv1483|M.tuberculosis_H37Rv         AVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLS
Mb1519|M.bovis_AF2122/97            AVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLS
MMAR_2289|M.marinum_M               AVTHRGSGAPEGLFGVECDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGLS
MUL_1491|M.ulcerans_Agy99           AVTHRGSGAPEGLFGVECDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGLS
Mflv_3658|M.gilvum_PYR-GCK          AVTHRGSGAPDGLFGVVCDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGIS
Mvan_2752|M.vanbaalenii_PYR-1       AVTHRGSGAPEGLFGVECDVTDNEAVDRAFAEVEEHQGPVEVLVSNAGIS
MAV_3295|M.avium_104                AVTHRGSGAPDGLFGVECDVTDNDAVDRAFTEVEEHQGPVEVLVSNAGIS
MSMEG_3150|M.smegmatis_MC2_155      AVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGIS
TH_3966|M.thermoresistible__bu      ---------PXX----------XESVDRAFKAVEEHQGPVEVLVANAGIS
MLBr_01807|M.leprae_Br4923          AVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGIT
MAB_2723c|M.abscessus_ATCC_199      AVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVANAGIT
                                             *               :. **  ***:********:***::

Rv1483|M.tuberculosis_H37Rv         ADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVS
Mb1519|M.bovis_AF2122/97            ADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVS
MMAR_2289|M.marinum_M               ADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQRKKFGRLIFIGSVS
MUL_1491|M.ulcerans_Agy99           ADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQRKKFGRLIFIGSVS
Mflv_3658|M.gilvum_PYR-GCK          KDAFLMRMTEDRFTDVIDANLTGAFRVAQRASRSMQRKRFGRIIFIGSVS
Mvan_2752|M.vanbaalenii_PYR-1       KDAFLMRMTEERFEEVINANLTGAFRVAQRASRSMQRKRFGRIIFIGSVS
MAV_3295|M.avium_104                KDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVS
MSMEG_3150|M.smegmatis_MC2_155      KDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRFGRIIFIGSVS
TH_3966|M.thermoresistible__bu      KDAFLMRMTEERFTEVIDTNLTGAFRVVQRASRTMQRKRFGRIILMGSVS
MLBr_01807|M.leprae_Br4923          SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSVV
MAB_2723c|M.abscessus_ATCC_199      ADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVA
                                     * :::**:*::* .**:.** *.** .: *:*.* :::*** * :*** 

Rv1483|M.tuberculosis_H37Rv         GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTR
Mb1519|M.bovis_AF2122/97            GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTR
MMAR_2289|M.marinum_M               GSWGIGNQANYAASKAGVIGMARSIARELSKVNVTANVVAPGYIDTDMTR
MUL_1491|M.ulcerans_Agy99           GSWGIGNQANYAASKAGVIGMARSIARELSKVNVTANVVAPGYIDTDMTR
Mflv_3658|M.gilvum_PYR-GCK          GMWGIGNQANYAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTR
Mvan_2752|M.vanbaalenii_PYR-1       GMWGIGNQANYAAAKAGLIGMARSISRELSKANVTANVVAPGYIDTEMTR
MAV_3295|M.avium_104                GMWGIGNQSNYAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTR
MSMEG_3150|M.smegmatis_MC2_155      GMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMTR
TH_3966|M.thermoresistible__bu      GTWGIGNQANYAAAKAGLIGMARSISRELSKANVTANVVAPGYIDTEMTR
MLBr_01807|M.leprae_Br4923          GLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTR
MAB_2723c|M.abscessus_ATCC_199      GQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFIDTDMTR
                                    *  *: .*:**:*:*:*::****:::***.. .:********:***:***

Rv1483|M.tuberculosis_H37Rv         ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG
Mb1519|M.bovis_AF2122/97            ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG
MMAR_2289|M.marinum_M               ALDERIQEGALQFIPAKRVGTAAEVAGVVSFLASEDASYISGAVIPVDGG
MUL_1491|M.ulcerans_Agy99           ALDERIQEGALQFIPAKRVGTAAEVAGVVSFLASEDASYISGAVIPVDGG
Mflv_3658|M.gilvum_PYR-GCK          ALDERIQAGALEFIPAKRVGTADEVAGAVSFLASEDASYIAGAVIPVDGG
Mvan_2752|M.vanbaalenii_PYR-1       ALDERIQAGALEFIPAKRVGTADEVAGAVSFLASEDASYIAGAVIPVDGG
MAV_3295|M.avium_104                ALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYIAGAVIPVDGG
MSMEG_3150|M.smegmatis_MC2_155      ALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGG
TH_3966|M.thermoresistible__bu      ALDERIQQGALDFIPAKRVGTAEEVAGVVSFLASEDAGYIAGAVIPVDGG
MLBr_01807|M.leprae_Br4923          AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGG
MAB_2723c|M.abscessus_ATCC_199      ELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGG
                                     :..:    **  **  *:*   *:**.**:*** **.*::*********

Rv1483|M.tuberculosis_H37Rv         MGMGH
Mb1519|M.bovis_AF2122/97            MGMGH
MMAR_2289|M.marinum_M               MGMGH
MUL_1491|M.ulcerans_Agy99           MGMGH
Mflv_3658|M.gilvum_PYR-GCK          MGMGH
Mvan_2752|M.vanbaalenii_PYR-1       MGMGH
MAV_3295|M.avium_104                MGMGH
MSMEG_3150|M.smegmatis_MC2_155      MGMGH
TH_3966|M.thermoresistible__bu      MGMGH
MLBr_01807|M.leprae_Br4923          LGMGH
MAB_2723c|M.abscessus_ATCC_199      LGMGH
                                    :****