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VMTTLDITVLRTFVAVTAFGGVRRAAQALHLSPAAVSSHVRRLERELGCRLVTAQGRGIGLTIDGEELAS RARMILQEHDDTVYALQRPRDDQLVVAASEHAAESLVPTVVSTLSEAYPDHEITLRLNRSERVRQLADDA RADVGIMLTRSGHAGVKVAALPLQWFGTETARRDRIVLFARPCAIRDPATASLTGLPYRIVKEAVDLTCL LTAVRQGYGVTPLPRTGPLPEGLRHITDLPGIPSVNLYLTTSSRIDLHVRTALLEALRTAIQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3972 | - | - | 100% (272) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_2544 | - | 4e-40 | 35.27% (275) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_1895 | - | 9e-13 | 28.90% (301) | HTH-type transcriptional regulator AlsR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 1e-12 | 35.25% (139) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 1e-09 | 27.94% (247) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 1e-12 | 35.25% (139) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02663 | oxyS | 2e-07 | 42.25% (71) | putative LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3179c | - | 1e-35 | 33.21% (277) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4902 | - | 1e-14 | 32.03% (256) | putative regulatory protein |
| M. avium 104 | MAV_0094 | - | 1e-36 | 36.23% (276) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_0172 | - | 4e-11 | 33.58% (137) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_3983 | - | 1e-09 | 37.50% (104) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4734 | - | 2e-11 | 30.34% (145) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3179c|M.abscessus_ATCC_199 MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGE
MAV_0094|M.avium_104 -MGQVLDIAPLRSLVAVADCGGFHRAAAALHLSQSAVSQHLRRIEAVVGE
MSMEG_3972|M.smegmatis_MC2_155 -MMTTLDITVLRTFVAVTAFGGVRRAAQALHLSPAAVSSHVRRLERELGC
Mb0384|M.bovis_AF2122/97 -----MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKELDD
Rv0377|M.tuberculosis_H37Rv -----MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKELDD
TH_0172|M.thermoresistible__bu -----MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKELDD
MMAR_4902|M.marinum_M ----MIDPHRLRILRAVVAEGSIGGAAAALGCTPSAVSQHIAVLQREIGL
MUL_3983|M.ulcerans_Agy99 ----MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLERECGM
Mflv_3565|M.gilvum_PYR-GCK -----MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSVGQ
Mvan_4734|M.vanbaalenii_PYR-1 -----MELRQLEAFVAVAGELHFGRAAEKLHIGQPTLSELIRRLEREVGT
MLBr_02663|M.leprae_Br4923 -----MLFRQLEYFVAVAQERHFARAAERCYVSQPALSSAIAKLERELNV
: : : . .* . :* : :. .
MAB_3179c|M.abscessus_ATCC_199 PVVRRYGRGVVFTDRGARLLVHARRILAAHDAAVDDLVAGQE---RALVL
MAV_0094|M.avium_104 PIVQRSGRGVVFTEVGQKALRHARTILAAHDTALDDLGATEN---KVLTI
MSMEG_3972|M.smegmatis_MC2_155 RLVTAQGRGIGLTIDGEELASRARMILQEHDDTVYALQRPRD---DQLVV
Mb0384|M.bovis_AF2122/97 PLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLLRI
Rv0377|M.tuberculosis_H37Rv PLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLLRI
TH_0172|M.thermoresistible__bu PLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHG-RRLLRI
MMAR_4902|M.marinum_M TLVEKVGRGIAPTDAGATLAAESAAVFDGLSRLDGLVADLRHGRAGTLRV
MUL_3983|M.ulcerans_Agy99 ALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRLRV
Mflv_3565|M.gilvum_PYR-GCK PLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSVAI
Mvan_4734|M.vanbaalenii_PYR-1 PLLTRTTRRVALTQAGVELFGRAKVILDDVEGAAAAVRRLADGEAGTVRL
MLBr_02663|M.leprae_Br4923 TLINRGHSFEGLTPEGERLVVWAKRILAEHDAFKAEVHAVRSGITGTLRL
:. * * : : : : :
MAB_3179c|M.abscessus_ATCC_199 GVTEHGADLILPSITSALRSHLPDWSVRVRFDR-NLYLAESVDRGIMDLA
MAV_0094|M.avium_104 GATEHGADVMLAGLSGALRDRLPDLRVRFRLDR-NVSLADSIDRGLVDVA
MSMEG_3972|M.smegmatis_MC2_155 AASEHAAESLVPTVVSTLSEAYPDHEITLRLNR-SERVRQLADDARADVG
Mb0384|M.bovis_AF2122/97 AASSAFAEHAAPGLIELFSSRADDLSVELSVHP-TSRFRELICSRAVDIA
Rv0377|M.tuberculosis_H37Rv AASSAFAEHAAPGLIELFSSRADDLSVELSVHP-TSRFRELICSRAVDIA
TH_0172|M.thermoresistible__bu AASHAFAEHAAPGLIDLFSSRADDLSVELTVEP-VSRFRDLLESRAVDVT
MMAR_4902|M.marinum_M SYFASAGAAWMPAVIATISSEYPAVRLDLRLVE-LADADDAAPDVEINVA
MUL_3983|M.ulcerans_Agy99 AAFRTLLLSLPPRVLDALARDYPDLRVEVAQRE-ADEATSGLLAGTFDVV
Mflv_3565|M.gilvum_PYR-GCK G-TVTLHPMNVAHLIAEFHADHPDVEITLGTAT-SDVLIAELGDGRLDLA
Mvan_4734|M.vanbaalenii_PYR-1 GITPPVAPVLAPHLSQALHSAAPDVQLVVQRMW-LPDLQRAIGDGELDVA
MLBr_02663|M.leprae_Br4923 G-TVPTASTTASLVLSAFCSEHPLIKVQICSRLPVTELHRRLGDFELDAV
. . : : : . :
MAB_3179c|M.abscessus_ATCC_199 V-------------ILDGSGLDRANAVGTVPLQWVAARGYKPNPIEPLRV
MAV_0094|M.avium_104 I-------------MLDGAGLDRANASGLVRLQWVSARTLTIAPKDPLPL
MSMEG_3972|M.smegmatis_MC2_155 I-------------MLTRSGHAGVKVA-ALPLQWFGTETARRD-----RI
Mb0384|M.bovis_AF2122/97 IGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLRHQQW
Rv0377|M.tuberculosis_H37Rv IGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLRHQQW
TH_0172|M.thermoresistible__bu LGPAVRE---PGPAIVVRPFLNYQIIAVTSPSNPLAAATPTIAQLRAQSW
MMAR_4902|M.marinum_M G--------------MPGTELSNYDTAALVTEDYVVVVGAGDSLAERDSV
MUL_3983|M.ulcerans_Agy99 LGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIGPWSDATTLSDLEYASW
Mflv_3565|M.gilvum_PYR-GCK IVSIAVDEDLPG---LEVAVITDEAVEAAVADGHPLAHRRSLSLEQLSRH
Mvan_4734|M.vanbaalenii_PYR-1 ITCGPVADP----PGILSEVFCAEPVMVGLRADHHLAGRDAVELRNLSTE
MLBr_02663|M.leprae_Br4923 IVHSAPDDT----HAVDLVPLYHEHYVLVSPADMLPPGASVLAWPEASQL
.
MAB_3179c|M.abscessus_ATCC_199 MTFTEPCT-------LRAPMFSALHTLGNQYQIVGES-PDLSGLYAGLRS
MAV_0094|M.avium_104 VIFSEPCT-------LREPAFAILDSHRIDYEIAAEC-GDLSGLYAAVRS
MSMEG_3972|M.smegmatis_MC2_155 VLFARPCA-------IRDPATASLT--GLPYRIVKEA-VDLTCLLTAVRQ
Mb0384|M.bovis_AF2122/97 MLGPSAGS-------VDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRV
Rv0377|M.tuberculosis_H37Rv MLGPSAGS-------VDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRV
TH_0172|M.thermoresistible__bu MLGPSAGG-------IDGDVAAMLRRLEIPEAAQRIFQSDSAAQEEVQRI
MMAR_4902|M.marinum_M TLRELAGEPWIDNDVARGNCRENLLRACTAAGFTPCFRVETHDYVTAVRF
MUL_3983|M.ulcerans_Agy99 ALDPEPTVP--------GRWARSVCRAAGFEPDVRFDGVDLLVHLQMVQA
Mflv_3565|M.gilvum_PYR-GCK PLISLPAGTG------LRTRLDTACAAAGLRPRIAFEATSPAELAELARH
Mvan_4734|M.vanbaalenii_PYR-1 TIGVHSEALFP---AWSLALRQVLDDTGIRPPAVEFTDTDLAAYRWPIQS
MLBr_02663|M.leprae_Br4923 PLALLTPDMR------DRQLIDRAFAGHAITATPQVETDSVASLFAQVAT
. .
MAB_3179c|M.abscessus_ATCC_199 G-------LGMALLPIIGWLP---------------DGIAPVDAMPAANL
MAV_0094|M.avium_104 G-------LGVALLPMIGKFP---------------DGLGPAEGLPPANN
MSMEG_3972|M.smegmatis_MC2_155 G-------YGVTPLPRTGPLP---------------EGLRHITDLPGIPS
Mb0384|M.bovis_AF2122/97 GGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
Rv0377|M.tuberculosis_H37Rv GGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
TH_0172|M.thermoresistible__bu GGVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSAARQPAASE
MMAR_4902|M.marinum_M VAAG----VGLTVVPRLALIDLP-------------AGVRTVAISEPTPR
MUL_3983|M.ulcerans_Agy99 G-------LAVAILPALLGQDRMRG-----------VRLAPLPASPKRQL
Mflv_3565|M.gilvum_PYR-GCK G-------LGVAILPQSMARGG--------------SGLHALRLAPELRG
Mvan_4734|M.vanbaalenii_PYR-1 EVDWVLTTAAVAGDSAGVVLRPTSP----------AHFVPYTLQWCPIRA
MLBr_02663|M.leprae_Br4923 G-------NWACIVPHTWLWTTPIG-----------AEIRAVEMVDPVLK
:
MAB_3179c|M.abscessus_ATCC_199 ATLSVVGRRGLDPVAFN--AVKDAAREALSGESAAIA-------
MAV_0094|M.avium_104 ASILVRGRTGIDPALLS--TVDTAVRDLLATAT-----------
MSMEG_3972|M.smegmatis_MC2_155 VNLYLTTSSRIDLHVRT--ALLEALRTAIQ--------------
Mb0384|M.bovis_AF2122/97 LVGFISTPRCIQAMIRG--SGVGVTRFRPKVHVTLWS-------
Rv0377|M.tuberculosis_H37Rv LVGFISTPRCIQAMIPG--SGVGVTRFRPKVHVTLWS-------
TH_0172|M.thermoresistible__bu LVRFITTPRCTQAMIRG--TSEGVTRFRPKVHVTLWS-------
MMAR_4902|M.marinum_M RTIVVRRHHRARNNVVAGRVLELIHQQAVRTHGPAVGALA----
MUL_3983|M.ulcerans_Agy99 FTLTRTSRTAHPAVVAFRTALAEGFDAQHQYD------------
Mflv_3565|M.gilvum_PYR-GCK RLVWAWRADGANPAARVLGERARAMAVSPGSGAPAVVPGA----
Mvan_4734|M.vanbaalenii_PYR-1 TTVAVGRFVRLALSVDVPPGWVSQPDHLRHGAGSLLED------
MLBr_02663|M.leprae_Br4923 ADVALATNSAGPGSPVARALVASAKQLALNEFFEAQLAGITRRR