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MRWTPDPEALRDRIAVVAGATRGAGRGIAAALGEAGATVYCTGRSSRTGTCRSDYDRPETIEETAELVSS LGGKGIAVPVDHLEVAQVRALAEQIGEEQGRIDILVNDIWGAEILKGPPATWGRPMWEHNLENGLRLLRL GIDTHLITSHCLLPLLVTRPGGLLVEISDGTTEFNADNYRLSVFYDLAKTAVNRLAFSHGHELAAYGGTA VSVTPGWLRSEMMLDNYGVCESNWEMALNPARGDGQPIAPPGFSESETPRFVGRGVAAIAADPARTRWNQ QSVTSTELARCYGFTDVDGRLPDAWAPM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3559 | - | - | 100% (308) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2923 | - | 9e-25 | 30.85% (295) | dehydrogenase/reductase SDR family protein member 1 |
| M. smegmatis MC2 155 | MSMEG_2885 | - | 3e-13 | 30.26% (228) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 2e-09 | 25.11% (227) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1260 | - | 1e-29 | 34.11% (299) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 2e-09 | 25.11% (227) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_00862 | ephD | 1e-06 | 32.76% (116) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0833 | - | 9e-12 | 28.37% (215) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_3513 | - | 1e-23 | 31.03% (290) | oxidoreductase |
| M. avium 104 | MAV_3035 | - | 2e-21 | 30.07% (296) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2904 | - | 2e-32 | 33.78% (296) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2755 | - | 1e-11 | 26.79% (209) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 5e-22 | 29.97% (297) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
Mb1963c|M.bovis_AF2122/97 --------------------------------------------------
Rv1928c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1260|M.gilvum_PYR-GCK --------------------------------------------------
TH_2904|M.thermoresistible__bu --------------------------------------------------
MMAR_3513|M.marinum_M --------------------------------------------------
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 --------------------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3559|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0833|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
Mb1963c|M.bovis_AF2122/97 -----------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVE
Rv1928c|M.tuberculosis_H37Rv -----------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVE
Mflv_1260|M.gilvum_PYR-GCK -----------------------MTADRPVAVVTGASRGAGAGIAHALGM
TH_2904|M.thermoresistible__bu -----------------------MSENSPVVVVTGASRGAGAGIAHALGS
MMAR_3513|M.marinum_M -----------------------MSDEALVAVVTGASRGAGRGIAAALAA
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 -----------------------------MAVVTGASRGAGRGISAALAD
Mvan_3919|M.vanbaalenii_PYR-1 -----------------------MGDIAPVAVVTGASRGAGQGIATALAG
MSMEG_3559|M.smegmatis_MC2_155 ----------------MRWTPDPEALRDRIAVVAGATRGAGRGIAAALGE
MAB_0833|M.abscessus_ATCC_1997 --------------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYAC
MLBr_00862|M.leprae_Br4923 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
Mb1963c|M.bovis_AF2122/97 AGAQVAIAARHLDA------------LEKLADEIGTSGGKVVPVCCDVSQ
Rv1928c|M.tuberculosis_H37Rv AGAQVAIAARHLDA------------LEKLADEIGTSGGKVVPVCCDVSQ
Mflv_1260|M.gilvum_PYR-GCK HGCTVYVTGRTVDP-----DGPAAGTIGETADEVTAAGGQGIAVRVDHSD
TH_2904|M.thermoresistible__bu HGCTVYVTGRTQRSG----AGGATGTIDDTADRVTAAGGTGIAVRVDHGD
MMAR_3513|M.marinum_M RGWRVYATSRSVAD----------------------APPGGVAVRVDHRD
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 RGWRVYATSRTIAD----------------------TPSGVVPVRVDHRD
Mvan_3919|M.vanbaalenii_PYR-1 RGWRVYGTGRTVAD----------------------APAWGTGVRVDHRD
MSMEG_3559|M.smegmatis_MC2_155 AGATVYCTGRSSRTGTCRSDYDRPETIEETAELVSSLGGKGIAVPVDHLE
MAB_0833|M.abscessus_ATCC_1997 AGANVVVASRKPEACT------------EAVERLRSLGARALGVPTHTGD
MLBr_00862|M.leprae_Br4923 RGAEVVVSDIDEAAAKN------------TAAQIVASGGVAYAYALDVSD
Mb1963c|M.bovis_AF2122/97 HQQVTSMLDQVTAELGGIDIAVC---NAGIITVT------PMLDMPLEEF
Rv1928c|M.tuberculosis_H37Rv HQQVTSMLDQVTAELGGIDIAVC---NAGIITVT------PMLDMPLEEF
Mflv_1260|M.gilvum_PYR-GCK DQQVAAFFDQIAREHGRIDILVN---NAAIIRDEMMGR-TKFWEEPIN-V
TH_2904|M.thermoresistible__bu DDQVRALFERIGREHGRIDILVN---NAAIIRDEMMGR-TKFWEEPIN-V
MMAR_3513|M.marinum_M DTATAALFERVQQESGRLDLLVN---NAAAISDDLVDP-KPFWEKPLA-L
MUL_2755|M.ulcerans_Agy99 ----------MQQESGRLDLLVN---NAAAISDDLVDP-KPFWEKPLA-L
MAV_3035|M.avium_104 DAAVSDLFDRVRRESGRLDLLVN---NAATISDNLVSS-KPFWEKPLD-L
Mvan_3919|M.vanbaalenii_PYR-1 DDAVGALFERVGAEAGRLDLLVN---NAAVISDDLVSP-KPFWEKPRA-L
MSMEG_3559|M.smegmatis_MC2_155 VAQVRALAEQIGEEQGRIDILVNDIWGAEILKGPPATWGRPMWEHNLENG
MAB_0833|M.abscessus_ATCC_1997 IHSLEELVRATAEEFGGIDIVVNN--AANALTEPVGAFTVDGWDKSFG--
MLBr_00862|M.leprae_Br4923 AAAVEAFAEQVSAKHGVPDIVVN---NAGIGQAG------RFLDTPPEEF
: * *: * * :
Mb1963c|M.bovis_AF2122/97 QRLQNTNVTGVFLTAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSH
Rv1928c|M.tuberculosis_H37Rv QRLQNTNVTGVFLTAQAAAKAMVKQGQGGVIINTASMSGHIINVPQQVSH
Mflv_1260|M.gilvum_PYR-GCK IDTLDVGVRSSYVATVYAAPLMVPNGRGLVVFTSS----SGAVHYAFGPA
TH_2904|M.thermoresistible__bu IDTLHVGLRSSYVATVYAAPLMLPQRRGLVVFTSS----SGGVHYAFGPA
MMAR_3513|M.marinum_M ADVLDVGLRSSYVASWYAAPLLVAGGRGLIAFTSS----PGSVCYMHGPA
MUL_2755|M.ulcerans_Agy99 ADVLDVGLRSSYVASWYAAPLLVAGGRGLIAFTSS----PGSVCYMHGPA
MAV_3035|M.avium_104 ADVLDVGLRSSYVASWYAAPLLVAGGRGLIAFTSS----PGSVCYMHGPA
Mvan_3919|M.vanbaalenii_PYR-1 ADVLDVGLRSAYIASWHAAPLLTAQQRGLVVFTSS----PGSVCYMHGPA
MSMEG_3559|M.smegmatis_MC2_155 LRLLRLGIDTHLITSHCLLPLLVTRPGGLLVEISDGTTEFNADNYRLSVF
MAB_0833|M.abscessus_ATCC_1997 -----VNLRGPVFLVQAALPHLVASPHAAVLNVVS---VGAFMFGQGVSM
MLBr_00862|M.leprae_Br4923 DRVLAVNLGGVVNCCRAFGQRLVERGTGGHIVNVS--SMAAYAPLQSLSA
.: : .
Mb1963c|M.bovis_AF2122/97 YCASKAAVIHLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQP---
Rv1928c|M.tuberculosis_H37Rv YCASKAAVIHLTKAMAVELAPHKIRVNSVSPGYILTELVEPYTEYQP---
Mflv_1260|M.gilvum_PYR-GCK YGVPKAATDKMAADMAYDFRDVGIAAVSIWMGSLLTDRVRGIIASNP---
TH_2904|M.thermoresistible__bu YGVPKAGADKMAADMAVDFREYGIAAVSIWMGSLLTERVRKIIASKP---
MMAR_3513|M.marinum_M YGAQKAGIDKMAADMAVDFHDTGVATVSIWMGILLTEKLRGAFGQHPD--
MUL_2755|M.ulcerans_Agy99 YGAQKAGIDKMAADMAVDFHDTGVATVSIWMGILLTEKLRGAFGQHPD--
MAV_3035|M.avium_104 YGAQKAGVDKMAADMAVDFRGTGVATVSIWMGILLTEKLRAAFGADP---
Mvan_3919|M.vanbaalenii_PYR-1 YGAQKAGVDKMAADMAVDFRGTGVSAVSIWMGILLTDKLRSAFDGSP---
MSMEG_3559|M.smegmatis_MC2_155 YDLAKTAVNRLAFSHGHELAAYGGTAVSVTPGWLRSEMMLDNYGVCESNW
MAB_0833|M.abscessus_ATCC_1997 YSAAKAALVSYTRSAAAELASRGVRVNALAPGAIDTDMVRKTPPAEVER-
MLBr_00862|M.leprae_Br4923 YCTSKAATYMFSDCLRAELDAVGVGLTTICPGVIDTNIIQSTRIDTPTAK
* *:. : :: :: * : :: :
Mb1963c|M.bovis_AF2122/97 -----------------LWEPKIPLGRLGRPEELAGLYLYLASEASSYMT
Rv1928c|M.tuberculosis_H37Rv -----------------LWEPKIPLGRLGRPEELAGLYLYLASEASSYMT
Mflv_1260|M.gilvum_PYR-GCK ------------EKFGRILDTAETPELTGHVIWALHQDPEVMALSGQTLI
TH_2904|M.thermoresistible__bu ------------EKFGHILDTAETPELTGHVIWALYRDPGLMSVSGQTLI
MMAR_3513|M.marinum_M ----------GQLALAKTAEHAETPEFTGYLIDALYRDPALGELSGQTVI
MUL_2755|M.ulcerans_Agy99 ----------GQRTLAKTAEHAETPEFTGYLIGALYRDPALGELSGQTVI
MAV_3035|M.avium_104 ------------AALAATAEHAETPEFTGYVIDALFDDPGLAELSGQTLI
Mvan_3919|M.vanbaalenii_PYR-1 ------------EALAAFAEQAETPEFTGHVIDALFRDPELDDVSGHTLI
MSMEG_3559|M.smegmatis_MC2_155 EMALNPARGDGQPIAPPGFSESETPRFVGRGVAAIAADPARTRWNQQSVT
MAB_0833|M.abscessus_ATCC_1997 ------------------MANTNHLKRLGLPDEMVGTALLLTSDAGSYIT
MLBr_00862|M.leprae_Br4923 Q--------ERVRDRRGQLDMMFRLRRYGPDKVADTILSAIKKNKPIRPV
*
Mb1963c|M.bovis_AF2122/97 GSDIVIDGGYTCP-------------------------
Rv1928c|M.tuberculosis_H37Rv GSDIVIDGGYTCP-------------------------
Mflv_1260|M.gilvum_PYR-GCK GAELAVKYGIRDEGDRQPPSYREMFDVHPPAQCAHVMR
TH_2904|M.thermoresistible__bu GAELAARYGIRDEDGRRPPSYRDLFGVHPRRQYGYMMR
MMAR_3513|M.marinum_M GAELAERYGITDEGGRRPPSHRHMLGA-PRTPSTVVVR
MUL_2755|M.ulcerans_Agy99 GAELAERYGITDEGGRRPPSHRHILGA-PRTPSTVVVR
MAV_3035|M.avium_104 GAELAQRYGITDEGGRRPPSHRDMLGS-PRTPSSVVVR
Mvan_3919|M.vanbaalenii_PYR-1 AAELATRYGITDEGGRTPPSHRQMLGA-PREPSPVIIR
MSMEG_3559|M.smegmatis_MC2_155 STELARCYGFTDVDGRLPDAWAPM--------------
MAB_0833|M.abscessus_ATCC_1997 GQTIIADGGLVAR-------------------------
MLBr_00862|M.leprae_Br4923 APEAYALYGISRVLPQVLRSTARIRVI-----------
. *