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VQQESGRLDLLVNNAAAISDDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLLVAGGRGLIAFTSS PGSVCYMHGPAYGAQKAGIDKMAADMAVDFHDTGVATVSIWMGILLTEKLRGAFGQHPDGQRTLAKTAEH AETPEFTGYLIGALYRDPALGELSGQTVIGAELAERYGITDEGGRRPPSHRHILGAPRTPSTVVVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2755 | - | - | 100% (206) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4844 | - | 6e-06 | 29.27% (123) | short-chain type dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0124 | - | 2e-05 | 28.18% (110) | ketoacyl reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2659 | - | 3e-88 | 78.64% (206) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0952 | - | 1e-05 | 29.94% (167) | short chain dehydrogenase |
| M. marinum M | MMAR_3513 | - | 1e-115 | 98.06% (206) | oxidoreductase |
| M. avium 104 | MAV_3035 | - | 2e-97 | 84.95% (206) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_2923 | - | 2e-91 | 80.58% (206) | dehydrogenase/reductase SDR family protein member 1 |
| M. thermoresistible (build 8) | TH_1294 | - | 9e-84 | 73.79% (206) | dehydrogenase/reductase SDR family protein member 1 |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 1e-86 | 75.24% (206) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3513|M.marinum_M ----------MSDEA----LVAVVTGASRGAGRGIAAALAARGWRVYATS
MAV_3035|M.avium_104 --------------------MAVVTGASRGAGRGISAALADRGWRVYATS
Mflv_2659|M.gilvum_PYR-GCK ----------MSDIAPVTGPVAVVTGAGRGAGLGIATALAAHGWRVYGTG
Mvan_3919|M.vanbaalenii_PYR-1 ----------MGDIA----PVAVVTGASRGAGQGIATALAGRGWRVYGTG
TH_1294|M.thermoresistible__bu ----------VTSEA----PVAVVTGASRGAGRGIARALLSRGWRVYGTG
MSMEG_2923|M.smegmatis_MC2_155 ----------------MDTPVAVVTGASRGAGRGIAAALLAAGWKVYVTG
MAB_0952|M.abscessus_ATCC_1997 MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAA
MUL_2755|M.ulcerans_Agy99 ----------------------------------------MQQESGRLDL
MMAR_3513|M.marinum_M RSVAD-----------APPGGVAVRVDHRDDTATAALFERVQQESGRLDL
MAV_3035|M.avium_104 RTIAD-----------TPSGVVPVRVDHRDDAAVSDLFDRVRRESGRLDL
Mflv_2659|M.gilvum_PYR-GCK RGIAE-----------DPAWGTGIRVDHRDDDAVGRVFDRVGAEAGRLDL
Mvan_3919|M.vanbaalenii_PYR-1 RTVAD-----------APAWGTGVRVDHRDDDAVGALFERVGAEAGRLDL
TH_1294|M.thermoresistible__bu RTVTD-----------ADG-VIPAPLDHADDSAVAALFDRVAAECGRLDL
MSMEG_2923|M.smegmatis_MC2_155 RTVTD-----------PGPGGVAVPVDHSDDVAVGALFRRVADESGRLDL
MAB_0952|M.abscessus_ATCC_1997 RSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGALDV
: * **:
MUL_2755|M.ulcerans_Agy99 LVNNAAAISDDLVDPKPFWEKPLALADVLDVGLR-SSYVASWYAAPLLVA
MMAR_3513|M.marinum_M LVNNAAAISDDLVDPKPFWEKPLALADVLDVGLR-SSYVASWYAAPLLVA
MAV_3035|M.avium_104 LVNNAATISDNLVSSKPFWEKPLDLADVLDVGLR-SSYVASWYAAPLLVA
Mflv_2659|M.gilvum_PYR-GCK LVNNAAAISDNLVSAAPFWEKPRDLADVLTVGLR-SSYIASWYAAPLLAA
Mvan_3919|M.vanbaalenii_PYR-1 LVNNAAVISDDLVSPKPFWEKPRALADVLDVGLR-SAYIASWHAAPLLTA
TH_1294|M.thermoresistible__bu LVNNAAAVHPALTDPRPFWQKSVELADILDIGLR-SAYVAAYHAAPLLLA
MSMEG_2923|M.smegmatis_MC2_155 LVNNAAAIHDALVDPKPFWEKPIELADVLDVGLR-SAYVASWHAAPLLLA
MAB_0952|M.abscessus_ATCC_1997 VCANAGIFPEARLDT----MTPEQLSEVLDVNVKGTVYTVQACLAPLTAS
: **. . .. .. *:::* :.:: : * . *** :
MUL_2755|M.ulcerans_Agy99 GGRGLIAFTSSPGSVC-YMHGPAYGAQKAGIDKMAADMAVDFHDTGVATV
MMAR_3513|M.marinum_M GGRGLIAFTSSPGSVC-YMHGPAYGAQKAGIDKMAADMAVDFHDTGVATV
MAV_3035|M.avium_104 GGRGLIAFTSSPGSVC-YMHGPAYGAQKAGVDKMAADMAVDFRGTGVATV
Mflv_2659|M.gilvum_PYR-GCK QDRALIAFTSSPGSVC-YMHGPAYGAQKAGVDKMAADMAVDFRGTGVATV
Mvan_3919|M.vanbaalenii_PYR-1 QQRGLVVFTSSPGSVC-YMHGPAYGAQKAGVDKMAADMAVDFRGTGVSAV
TH_1294|M.thermoresistible__bu ADRALIAFTSSPGSVC-YMHGPAYGAQKAGIDKMAADMAVDFRGTPVCTV
MSMEG_2923|M.smegmatis_MC2_155 GDKGLIAFTSSPGSVC-YMHGPAYGAQKAGVDKLAADMAVDFRGTSVCTV
MAB_0952|M.abscessus_ATCC_1997 GRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVN
:: :* .*.* * . ***.**. : *::: * .
MUL_2755|M.ulcerans_Agy99 SIWMGILLTEKLRGAFGQHPDGQRTLAKTAEHAETPEFTGYLIGALYRDP
MMAR_3513|M.marinum_M SIWMGILLTEKLRGAFGQHPDGQLALAKTAEHAETPEFTGYLIDALYRDP
MAV_3035|M.avium_104 SIWMGILLTEKLRAAFGADP---AALAATAEHAETPEFTGYVIDALFDDP
Mflv_2659|M.gilvum_PYR-GCK SVWMGILLTAKLRGAFDSDP---DALAAFAAHAETPEFTGHVIDALFRDP
Mvan_3919|M.vanbaalenii_PYR-1 SIWMGILLTDKLRSAFDGSP---EALAAFAEQAETPEFTGHVIDALFRDP
TH_1294|M.thermoresistible__bu SIWMGILLTEQMRRAFTGRP---DALAAMAEHAETPEFTGHILDALYRDP
MSMEG_2923|M.smegmatis_MC2_155 SIWMGILLTEKLRAAFAGNP---EALAETAKHAETPEFTGRLIDALYRDP
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVDMGEEYISG-MARSIPMGMLGSPVDIGHLAAFLATD-
:: * :** : : : :* * : * *
MUL_2755|M.ulcerans_Agy99 ALGELSGQTVIGAELAERYGITDEGGRRPPSHRHILGAPRTPSTVVVR
MMAR_3513|M.marinum_M ALGELSGQTVIGAELAERYGITDEGGRRPPSHRHMLGAPRTPSTVVVR
MAV_3035|M.avium_104 GLAELSGQTLIGAELAQRYGITDEGGRRPPSHRDMLGSPRTPSSVVVR
Mflv_2659|M.gilvum_PYR-GCK GLADLSGHTVIGAELAARYGITDEGGRTPPSHRGMLGEPRTPSAVVVR
Mvan_3919|M.vanbaalenii_PYR-1 ELDDVSGHTLIAAELATRYGITDEGGRTPPSHRQMLGAPREPSPVIIR
TH_1294|M.thermoresistible__bu QLEQLSGHTLIGAELAERYNITDEGGRRPPSHRAMLGDPRPPSDVVVR
MSMEG_2923|M.smegmatis_MC2_155 QLGELSGQTVIGAELATRYGITDEGGRIPPSHREMLGAPRVAHPAVVR
MAB_0952|M.abscessus_ATCC_1997 EAGYITGQAIV-----------VDGGQVLPESPDAVNP----------
::*:::: :**: *. :.