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MDTPVAVVTGASRGAGRGIAAALLAAGWKVYVTGRTVTDPGPGGVAVPVDHSDDVAVGALFRRVADESGR LDLLVNNAAAIHDALVDPKPFWEKPIELADVLDVGLRSAYVASWHAAPLLLAGDKGLIAFTSSPGSVCYM HGPAYGAQKAGVDKLAADMAVDFRGTSVCTVSIWMGILLTEKLRAAFAGNPEALAETAKHAETPEFTGRL IDALYRDPQLGELSGQTVIGAELATRYGITDEGGRIPPSHREMLGAPRVAHPAVVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2923 | - | - | 100% (266) | dehydrogenase/reductase SDR family protein member 1 |
| M. smegmatis MC2 155 | MSMEG_3559 | - | 7e-25 | 30.85% (295) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6626 | - | 2e-14 | 34.90% (192) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2882c | - | 9e-13 | 30.00% (220) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2659 | - | 1e-107 | 73.00% (263) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2857c | - | 1e-12 | 30.00% (220) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-11 | 28.72% (188) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4632 | - | 7e-12 | 32.21% (208) | short chain dehydrogenase |
| M. marinum M | MMAR_3513 | - | 1e-118 | 80.38% (265) | oxidoreductase |
| M. avium 104 | MAV_3035 | - | 1e-113 | 77.48% (262) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_1294 | - | 1e-115 | 75.85% (265) | dehydrogenase/reductase SDR family protein member 1 |
| M. ulcerans Agy99 | MUL_2755 | - | 2e-91 | 80.58% (206) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 1e-113 | 75.67% (263) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2659|M.gilvum_PYR-GCK -MSDIAPVTG-----------PVAVVTGAGRGAGLGIATALAAHGWRVYG
Mvan_3919|M.vanbaalenii_PYR-1 -MGDIA---------------PVAVVTGASRGAGQGIATALAGRGWRVYG
MMAR_3513|M.marinum_M -MSDEA---------------LVAVVTGASRGAGRGIAAALAARGWRVYA
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 ----------------------MAVVTGASRGAGRGISAALADRGWRVYA
MSMEG_2923|M.smegmatis_MC2_155 -------MDT-----------PVAVVTGASRGAGRGIAAALLAAGWKVYV
TH_1294|M.thermoresistible__bu -----VTSEA-----------PVAVVTGASRGAGRGIARALLSRGWRVYG
Mb2882c|M.bovis_AF2122/97 MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
Rv2857c|M.tuberculosis_H37Rv MMDLSQRLAG-----------RVAVITGGGSGIGLAAGRRMRAEGATIVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_4632|M.abscessus_ATCC_1997 MILDRFKLDG-----------NVAVVTGAGRGLGAAIAEAFAQAGADVLI
Mflv_2659|M.gilvum_PYR-GCK ----------TGRGIAEDPAWGTGIRVDHRDDDAVGRVFDRVGAEAGRLD
Mvan_3919|M.vanbaalenii_PYR-1 ----------TGRTVADAPAWGTGVRVDHRDDDAVGALFERVGAEAGRLD
MMAR_3513|M.marinum_M ----------TSRSVADAPPGGVAVRVDHRDDTATAALFERVQQESGRLD
MUL_2755|M.ulcerans_Agy99 -----------------------------------------MQQESGRLD
MAV_3035|M.avium_104 ----------TSRTIADTPSGVVPVRVDHRDDAAVSDLFDRVRRESGRLD
MSMEG_2923|M.smegmatis_MC2_155 ----------TGRTVTDPGPGGVAVPVDHSDDVAVGALFRRVADESGRLD
TH_1294|M.thermoresistible__bu ----------TGRTVTDADG-VIPAPLDHADDSAVAALFDRVAAECGRLD
Mb2882c|M.bovis_AF2122/97 GD-----VDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRID
Rv2857c|M.tuberculosis_H37Rv GD-----VDVEAGGAAADELSGLFVPTDVCDEDAVNGLFDGAAETYGRID
MLBr_01807|M.leprae_Br4923 ---------THRASVVPDWFFG--VECDVTDNDAIGAAFKAVEEHQGPVE
MAB_4632|M.abscessus_ATCC_1997 ASRTESQLREVAAKVQAAGRQAEVVVADLSDTEASAALAQKAVDRFGRLD
* ::
Mflv_2659|M.gilvum_PYR-GCK LLVNNAAAIS--DNLVSAAPFWEKPRDLADVLTVGLRSSYIASWYAAPLL
Mvan_3919|M.vanbaalenii_PYR-1 LLVNNAAVIS--DDLVSPKPFWEKPRALADVLDVGLRSAYIASWHAAPLL
MMAR_3513|M.marinum_M LLVNNAAAIS--DDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLL
MUL_2755|M.ulcerans_Agy99 LLVNNAAAIS--DDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLL
MAV_3035|M.avium_104 LLVNNAATIS--DNLVSSKPFWEKPLDLADVLDVGLRSSYVASWYAAPLL
MSMEG_2923|M.smegmatis_MC2_155 LLVNNAAAIH--DALVDPKPFWEKPIELADVLDVGLRSAYVASWHAAPLL
TH_1294|M.thermoresistible__bu LLVNNAAAVH--PALTDPRPFWQKSVELADILDIGLRSAYVAAYHAAPLL
Mb2882c|M.bovis_AF2122/97 IAFNNAGISPPEDNLIEN----TELAAWQRVQDVNLKSVYLCCRAALRHM
Rv2857c|M.tuberculosis_H37Rv IAFNNAGISPPEDNLIEN----TELAAWQRVQDVNLKSVYLCCRAALRHM
MLBr_01807|M.leprae_Br4923 VLVANAGITS--DMLIMR----MSEEQFQKVIDVNLTGVFRVAKLASRNM
MAB_4632|M.abscessus_ATCC_1997 VVVNNVGGTMP-KPFLDT-----TNDDLAEAFSFNVLSGHALLRAAVPHL
: . *.. : ..: . . * :
Mflv_2659|M.gilvum_PYR-GCK AAQDRALIAFTSSPGSVCY--MHGPAYGAQKAGVDKMAADMAVDFRGTGV
Mvan_3919|M.vanbaalenii_PYR-1 TAQQRGLVVFTSSPGSVCY--MHGPAYGAQKAGVDKMAADMAVDFRGTGV
MMAR_3513|M.marinum_M VAGGRGLIAFTSSPGSVCY--MHGPAYGAQKAGIDKMAADMAVDFHDTGV
MUL_2755|M.ulcerans_Agy99 VAGGRGLIAFTSSPGSVCY--MHGPAYGAQKAGIDKMAADMAVDFHDTGV
MAV_3035|M.avium_104 VAGGRGLIAFTSSPGSVCY--MHGPAYGAQKAGVDKMAADMAVDFRGTGV
MSMEG_2923|M.smegmatis_MC2_155 LAGDKGLIAFTSSPGSVCY--MHGPAYGAQKAGVDKLAADMAVDFRGTSV
TH_1294|M.thermoresistible__bu LAADRALIAFTSSPGSVCY--MHGPAYGAQKAGIDKMAADMAVDFRGTPV
Mb2882c|M.bovis_AF2122/97 VLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGI
Rv2857c|M.tuberculosis_H37Rv VLAGKGSIVNTASFVAVMGSATSQISYTASKGGVLAMSRELGVQFARQGI
MLBr_01807|M.leprae_Br4923 IKQRFGRYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSI
MAB_4632|M.abscessus_ATCC_1997 LKSDNASVINITSTMGRLPG-RAFLGYCTAKGALAHYTRTAAMDLSPR-I
. * . * : *..: : . :: :
Mflv_2659|M.gilvum_PYR-GCK ATVSVWMGILLTAKLRGAFDSDP---DALAAFAAHAETPEFTGHVIDALF
Mvan_3919|M.vanbaalenii_PYR-1 SAVSIWMGILLTDKLRSAFDGSP---EALAAFAEQAETPEFTGHVIDALF
MMAR_3513|M.marinum_M ATVSIWMGILLTEKLRGAFGQHPDGQLALAKTAEHAETPEFTGYLIDALY
MUL_2755|M.ulcerans_Agy99 ATVSIWMGILLTEKLRGAFGQHPDGQRTLAKTAEHAETPEFTGYLIGALY
MAV_3035|M.avium_104 ATVSIWMGILLTEKLRAAFGADP---AALAATAEHAETPEFTGYVIDALF
MSMEG_2923|M.smegmatis_MC2_155 CTVSIWMGILLTEKLRAAFAGNP---EALAETAKHAETPEFTGRLIDALY
TH_1294|M.thermoresistible__bu CTVSIWMGILLTEQMRRAFTGRP---DALAAMAEHAETPEFTGHILDALY
Mb2882c|M.bovis_AF2122/97 RVNALCPGPVNTPLLQELFAKNP--------------ERAARRMVHVPLG
Rv2857c|M.tuberculosis_H37Rv RVNALCPGPVNTPLLQELFAKNP--------------ERAARRMVHVPLG
MLBr_01807|M.leprae_Br4923 TANVVAPGFIDTEMTRAMDSKYQ--------------EAALQ---AIPLG
MAB_4632|M.abscessus_ATCC_1997 RVNGIAPGSILTSALEVVAGNDE---------------MRNTLEQNTPLH
. : * : * . .*
Mflv_2659|M.gilvum_PYR-GCK RDPGLADLSGHTVIGAELAARYGITDEGGRTPPSHRGMLGEPRTPSAVVV
Mvan_3919|M.vanbaalenii_PYR-1 RDPELDDVSGHTLIAAELATRYGITDEGGRTPPSHRQMLGAPREPSPVII
MMAR_3513|M.marinum_M RDPALGELSGQTVIGAELAERYGITDEGGRRPPSHRHMLGAPRTPSTVVV
MUL_2755|M.ulcerans_Agy99 RDPALGELSGQTVIGAELAERYGITDEGGRRPPSHRHILGAPRTPSTVVV
MAV_3035|M.avium_104 DDPGLAELSGQTLIGAELAQRYGITDEGGRRPPSHRDMLGSPRTPSSVVV
MSMEG_2923|M.smegmatis_MC2_155 RDPQLGELSGQTVIGAELATRYGITDEGGRIPPSHREMLGAPRVAHPAVV
TH_1294|M.thermoresistible__bu RDPQLEQLSGHTLIGAELAERYNITDEGGRRPPSHRAMLGDPRPPSDVVV
Mb2882c|M.bovis_AF2122/97 RFAEPDEIAA--------AVAFLASDDASFITASTFLVDGGISSAYVTPL
Rv2857c|M.tuberculosis_H37Rv RFAEPDEIAA--------AVAFLASDDASFITASTFLVDGGISSAYVTPL
MLBr_01807|M.leprae_Br4923 RIGAVEEIAG--------AVSFLASEDAGYISGAVIPVDGGLGMGH----
MAB_4632|M.abscessus_ATCC_1997 RLGDPADIAA--------AAVYLASPAGSFLTGKVLEVDGGLIAPNLDIP
:::. * : : .. . : *
Mflv_2659|M.gilvum_PYR-GCK R----
Mvan_3919|M.vanbaalenii_PYR-1 R----
MMAR_3513|M.marinum_M R----
MUL_2755|M.ulcerans_Agy99 R----
MAV_3035|M.avium_104 R----
MSMEG_2923|M.smegmatis_MC2_155 R----
TH_1294|M.thermoresistible__bu R----
Mb2882c|M.bovis_AF2122/97 -----
Rv2857c|M.tuberculosis_H37Rv -----
MLBr_01807|M.leprae_Br4923 -----
MAB_4632|M.abscessus_ATCC_1997 LPDLA