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AVVTGASRGAGRGISAALADRGWRVYATSRTIADTPSGVVPVRVDHRDDAAVSDLFDRVRRESGRLDLLV NNAATISDNLVSSKPFWEKPLDLADVLDVGLRSSYVASWYAAPLLVAGGRGLIAFTSSPGSVCYMHGPAY GAQKAGVDKMAADMAVDFRGTGVATVSIWMGILLTEKLRAAFGADPAALAATAEHAETPEFTGYVIDALF DDPGLAELSGQTLIGAELAQRYGITDEGGRRPPSHRDMLGSPRTPSSVVVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3035 | - | - | 100% (262) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_5213 | - | 2e-14 | 28.85% (260) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. avium 104 | MAV_1391 | - | 6e-13 | 28.33% (240) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 2e-13 | 25.69% (253) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2659 | - | 1e-117 | 80.15% (262) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1941 | - | 2e-13 | 25.69% (253) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-09 | 28.02% (182) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0607 | - | 9e-12 | 30.73% (205) | short chain dehydrogenase |
| M. marinum M | MMAR_3513 | - | 1e-126 | 84.53% (265) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2923 | - | 1e-113 | 77.48% (262) | dehydrogenase/reductase SDR family protein member 1 |
| M. thermoresistible (build 8) | TH_1294 | - | 1e-109 | 72.90% (262) | dehydrogenase/reductase SDR family protein member 1 |
| M. ulcerans Agy99 | MUL_2755 | - | 3e-97 | 84.95% (206) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 1e-114 | 77.48% (262) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3513|M.marinum_M ------------MSDEA----LVAVVTGASRGAGRGIAAALAARGWRVYA
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 ----------------------MAVVTGASRGAGRGISAALADRGWRVYA
Mflv_2659|M.gilvum_PYR-GCK ------------MSDIAPVTGPVAVVTGAGRGAGLGIATALAAHGWRVYG
Mvan_3919|M.vanbaalenii_PYR-1 ------------MGDIA----PVAVVTGASRGAGQGIATALAGRGWRVYG
MSMEG_2923|M.smegmatis_MC2_155 ------------------MDTPVAVVTGASRGAGRGIAAALLAAGWKVYV
TH_1294|M.thermoresistible__bu ----------------VTSEAPVAVVTGASRGAGRGIARALLSRGWRVYG
Mb1976|M.bovis_AF2122/97 -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0607|M.abscessus_ATCC_1997 ----------MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVT
MMAR_3513|M.marinum_M TSR-------SVADAPPGGVAVRVDHRDDTATAALFERVQQESGRLDLLV
MUL_2755|M.ulcerans_Agy99 --------------------------------------MQQESGRLDLLV
MAV_3035|M.avium_104 TSR-------TIADTPSGVVPVRVDHRDDAAVSDLFDRVRRESGRLDLLV
Mflv_2659|M.gilvum_PYR-GCK TGR-------GIAEDPAWGTGIRVDHRDDDAVGRVFDRVGAEAGRLDLLV
Mvan_3919|M.vanbaalenii_PYR-1 TGR-------TVADAPAWGTGVRVDHRDDDAVGALFERVGAEAGRLDLLV
MSMEG_2923|M.smegmatis_MC2_155 TGR-------TVTDPGPGGVAVPVDHSDDVAVGALFRRVADESGRLDLLV
TH_1294|M.thermoresistible__bu TGR-------TVTDADG-VIPAPLDHADDSAVAALFDRVAAECGRLDLLV
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIGCGAAACRVDVSDEQQIIAMVDACVAAFGGVDKLV
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIGCGAAACRVDVSDEQQIIAMVDACVAAFGGVDKLV
MLBr_01807|M.leprae_Br4923 THR--------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLV
MAB_0607|M.abscessus_ATCC_1997 CAR---------RPGDAPYEFHSCDVRDEESVDTLIGAIVAAHGRLDAVV
* :: :*
MMAR_3513|M.marinum_M NNAAAISDDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLLVAG--
MUL_2755|M.ulcerans_Agy99 NNAAAISDDLVDPKPFWEKPLALADVLDVGLRSSYVASWYAAPLLVAG--
MAV_3035|M.avium_104 NNAATISDNLVSSKPFWEKPLDLADVLDVGLRSSYVASWYAAPLLVAG--
Mflv_2659|M.gilvum_PYR-GCK NNAAAISDNLVSAAPFWEKPRDLADVLTVGLRSSYIASWYAAPLLAAQ--
Mvan_3919|M.vanbaalenii_PYR-1 NNAAVISDDLVSPKPFWEKPRALADVLDVGLRSAYIASWHAAPLLTAQ--
MSMEG_2923|M.smegmatis_MC2_155 NNAAAIHDALVDPKPFWEKPIELADVLDVGLRSAYVASWHAAPLLLAG--
TH_1294|M.thermoresistible__bu NNAAAVHPALTDPRPFWQKSVELADILDIGLRSAYVAAYHAAPLLLAA--
Mb1976|M.bovis_AF2122/97 ANAGVVHLASLIDTTVED----FDRVIAINLRGAWLCTKHAAPRMIER-G
Rv1941|M.tuberculosis_H37Rv ANAGVVHLASLIDTTVED----FDRVIAINLRGAWLCTKHAAPRMIER-G
MLBr_01807|M.leprae_Br4923 ANAGITSDMLIMRMSEEQ----FQKVIDVNLTGVFRVAKLASRNMIKQ-R
MAB_0607|M.abscessus_ATCC_1997 NNAGGAPFALAADASHNF----HRKIIELNLLSALLVSQRANAVMQKQDG
**. . :: :.* . : * :
MMAR_3513|M.marinum_M GRGLIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFHDTGVATVSI
MUL_2755|M.ulcerans_Agy99 GRGLIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFHDTGVATVSI
MAV_3035|M.avium_104 GRGLIAFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVATVSI
Mflv_2659|M.gilvum_PYR-GCK DRALIAFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVATVSV
Mvan_3919|M.vanbaalenii_PYR-1 QRGLVVFTSSPGSVCYMHGPAYGAQKAGVDKMAADMAVDFRGTGVSAVSI
MSMEG_2923|M.smegmatis_MC2_155 DKGLIAFTSSPGSVCYMHGPAYGAQKAGVDKLAADMAVDFRGTSVCTVSI
TH_1294|M.thermoresistible__bu DRALIAFTSSPGSVCYMHGPAYGAQKAGIDKMAADMAVDFRGTPVCTVSI
Mb1976|M.bovis_AF2122/97 GGAIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTL
Rv1941|M.tuberculosis_H37Rv GGAIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTL
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MAB_0607|M.abscessus_ATCC_1997 GGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAP-KVRVNAL
: : * . *. *:*: :: * : : :
MMAR_3513|M.marinum_M WMGILLTEKLRGAFGQHPDGQLALAKTAEHAETPEFTGYLIDALYRDPAL
MUL_2755|M.ulcerans_Agy99 WMGILLTEKLRGAFGQHPDGQRTLAKTAEHAETPEFTGYLIGALYRDPAL
MAV_3035|M.avium_104 WMGILLTEKLRAAFGADP---AALAATAEHAETPEFTGYVIDALFDDPGL
Mflv_2659|M.gilvum_PYR-GCK WMGILLTAKLRGAFDSDP---DALAAFAAHAETPEFTGHVIDALFRDPGL
Mvan_3919|M.vanbaalenii_PYR-1 WMGILLTDKLRSAFDGSP---EALAAFAEQAETPEFTGHVIDALFRDPEL
MSMEG_2923|M.smegmatis_MC2_155 WMGILLTEKLRAAFAGNP---EALAETAKHAETPEFTGRLIDALYRDPQL
TH_1294|M.thermoresistible__bu WMGILLTEQMRRAFTGRP---DALAAMAEHAETPEFTGHILDALYRDPQL
Mb1976|M.bovis_AF2122/97 LPAFVDTPMQQTAMAMFD---GALGAGGARSMIARLQGRMAAPEEMAGIV
Rv1941|M.tuberculosis_H37Rv LPAFVDTPMQQTAMAMFD---GALGAGGARSMIARLQGRMAAPEEMAGIV
MLBr_01807|M.leprae_Br4923 APGFIDTEMTRAMDSKYQ---EAA-------LQAIPLGRIGAVEEIAGAV
MAB_0607|M.abscessus_ATCC_1997 AAGMIRTELSEMHYGDED---GIAAVG-----ATVPLGRLANPDEIGWTA
.:: * . . * :
MMAR_3513|M.marinum_M GELSGQTVIGAELAERYGITDEGGRRPPSHRHMLGAPRTPSTVVVR
MUL_2755|M.ulcerans_Agy99 GELSGQTVIGAELAERYGITDEGGRRPPSHRHILGAPRTPSTVVVR
MAV_3035|M.avium_104 AELSGQTLIGAELAQRYGITDEGGRRPPSHRDMLGSPRTPSSVVVR
Mflv_2659|M.gilvum_PYR-GCK ADLSGHTVIGAELAARYGITDEGGRTPPSHRGMLGEPRTPSAVVVR
Mvan_3919|M.vanbaalenii_PYR-1 DDVSGHTLIAAELATRYGITDEGGRTPPSHRQMLGAPREPSPVIIR
MSMEG_2923|M.smegmatis_MC2_155 GELSGQTVIGAELATRYGITDEGGRIPPSHREMLGAPRVAHPAVVR
TH_1294|M.thermoresistible__bu EQLSGHTLIGAELAERYNITDEGGRRPPSHRAMLGDPRPPSDVVVR
Mb1976|M.bovis_AF2122/97 VFLLSDDAS---MITGTTQIADGGTIAALW----------------
Rv1941|M.tuberculosis_H37Rv VFLLSDDAS---MITGTTQIADGGTIAALW----------------
MLBr_01807|M.leprae_Br4923 SFLASEDAG---YISGAVIPVDGGLGMGH-----------------
MAB_0607|M.abscessus_ATCC_1997 AFLASPLSS---YVTGSVLTVHGGGERPAFLDAANVNSNENGEKE-
: . .**