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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2904 | - | - | 100% (288) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_1294 | - | 3e-73 | 52.36% (275) | dehydrogenase/reductase SDR family protein member 1 |
| M. thermoresistible (build 8) | TH_4146 | - | 2e-16 | 30.83% (240) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3578c | - | 1e-16 | 29.96% (227) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1260 | - | 1e-128 | 79.44% (287) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3548c | - | 2e-16 | 29.96% (227) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_02565 | fabG | 3e-10 | 28.09% (267) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. abscessus ATCC 19977 | MAB_0608 | - | 4e-14 | 26.98% (215) | short chain dehydrogenase |
| M. marinum M | MMAR_3513 | - | 5e-77 | 54.68% (278) | oxidoreductase |
| M. avium 104 | MAV_3035 | - | 4e-78 | 55.87% (281) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_2923 | - | 2e-77 | 54.93% (284) | dehydrogenase/reductase SDR family protein member 1 |
| M. ulcerans Agy99 | MUL_2755 | - | 3e-60 | 58.46% (195) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3919 | - | 3e-81 | 56.10% (287) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2904|M.thermoresistible__bu ---MSENSPVVVVTGASRG--------------------AGAGIAHALGS
Mflv_1260|M.gilvum_PYR-GCK ---MTADRPVAVVTGASRG--------------------AGAGIAHALGM
MMAR_3513|M.marinum_M ---MSDEALVAVVTGASRG--------------------AGRGIAAALAA
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 ---------MAVVTGASRG--------------------AGRGISAALAD
MSMEG_2923|M.smegmatis_MC2_155 -----MDTPVAVVTGASRG--------------------AGRGIAAALLA
Mvan_3919|M.vanbaalenii_PYR-1 ---MGDIAPVAVVTGASRG--------------------AGQGIATALAG
Mb3578c|M.bovis_AF2122/97 --MGLVDGRVVIVTGAGGG--------------------IGRAHALAFAA
Rv3548c|M.tuberculosis_H37Rv --MGLVDGRVVIVTGAGGG--------------------IGRAHALAFAA
MAB_0608|M.abscessus_ATCC_1997 -MPGLLDGRVVIITGAGRG--------------------IGRAHALAFAA
MLBr_02565|M.leprae_Br4923 MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
TH_2904|M.thermoresistible__bu HGCTVYVTGRTQ--RSGAGGATGTIDDTADRVTAAGGTGIAVRVDHGDDD
Mflv_1260|M.gilvum_PYR-GCK HGCTVYVTGRTV--DP-DGPAAGTIGETADEVTAAGGQGIAVRVDHSDDQ
MMAR_3513|M.marinum_M RGWRVYATSR--------------------SVADAPPGGVAVRVDHRDDT
MUL_2755|M.ulcerans_Agy99 --------------------------------------------------
MAV_3035|M.avium_104 RGWRVYATSR--------------------TIADTPSGVVPVRVDHRDDA
MSMEG_2923|M.smegmatis_MC2_155 AGWKVYVTGR--------------------TVTDPGPGGVAVPVDHSDDV
Mvan_3919|M.vanbaalenii_PYR-1 RGWRVYGTGR--------------------TVADAPAWGTGVRVDHRDDD
Mb3578c|M.bovis_AF2122/97 EGARVVVNDIGVGLDGSPASGGSAAQDVVDEILAAGGQAVADGSDISDWD
Rv3548c|M.tuberculosis_H37Rv EGARVVVNDIGVGLDGSPASGGSAAQDVVDEILAAGGQAVADGSDISDWD
MAB_0608|M.abscessus_ATCC_1997 EGARVVVNDIGVGLDGS--AGISPAQEVVEEITAAGGEAVTNGDDVADWS
MLBr_02565|M.leprae_Br4923 GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
TH_2904|M.thermoresistible__bu QVRALFERIGREHGRIDILVNN-----AAIIRDEMMGRTKFWEEPINVID
Mflv_1260|M.gilvum_PYR-GCK QVAAFFDQIAREHGRIDILVNN-----AAIIRDEMMGRTKFWEEPINVID
MMAR_3513|M.marinum_M ATAALFERVQQESGRLDLLVNN-----AAAISDDLVDPKPFWEKPLALAD
MUL_2755|M.ulcerans_Agy99 --------MQQESGRLDLLVNN-----AAAISDDLVDPKPFWEKPLALAD
MAV_3035|M.avium_104 AVSDLFDRVRRESGRLDLLVNN-----AATISDNLVSSKPFWEKPLDLAD
MSMEG_2923|M.smegmatis_MC2_155 AVGALFRRVADESGRLDLLVNN-----AAAIHDALVDPKPFWEKPIELAD
Mvan_3919|M.vanbaalenii_PYR-1 AVGALFERVGAEAGRLDLLVNN-----AAVISDDLVSPKPFWEKPRALAD
Mb3578c|M.bovis_AF2122/97 QAANLIQAAVETYGGVDVLVNN-----AGIVRDRMIANTSEEEFDAVIAV
Rv3548c|M.tuberculosis_H37Rv QAANLIQAAVETYGGVDVLVNN-----AGIVRDRMIANTSEEEFDAVIAV
MAB_0608|M.abscessus_ATCC_1997 GAKNLIDTAVNSFGRLDVLVNN-----AGFLRDRMLANMSEEEWDAVIRV
MLBr_02565|M.leprae_Br4923 GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
* :* * * : :
TH_2904|M.thermoresistible__bu TLHVGLRSSYVATVYAAPLMLPQRR------GLVVFTSSSGGVHYAFGPA
Mflv_1260|M.gilvum_PYR-GCK TLDVGVRSSYVATVYAAPLMVPNGR------GLVVFTSSSGAVHYAFGPA
MMAR_3513|M.marinum_M VLDVGLRSSYVASWYAAPLLVAGGR------GLIAFTSSPGSVCYMHGPA
MUL_2755|M.ulcerans_Agy99 VLDVGLRSSYVASWYAAPLLVAGGR------GLIAFTSSPGSVCYMHGPA
MAV_3035|M.avium_104 VLDVGLRSSYVASWYAAPLLVAGGR------GLIAFTSSPGSVCYMHGPA
MSMEG_2923|M.smegmatis_MC2_155 VLDVGLRSAYVASWHAAPLLLAGDK------GLIAFTSSPGSVCYMHGPA
Mvan_3919|M.vanbaalenii_PYR-1 VLDVGLRSAYIASWHAAPLLTAQQR------GLVVFTSSPGSVCYMHGPA
Mb3578c|M.bovis_AF2122/97 HLKGHFATMRHAASHWRGLSKAGKAPKDIDARIINTSSGAGLQGSVGQGN
Rv3548c|M.tuberculosis_H37Rv HLKGHFATMRHAASHWRGLSKAGKAPKDIDARIINTSSGAGLQGSVGQGN
MAB_0608|M.abscessus_ATCC_1997 HLKGHFAPLRHAAAYWRDEFKAGNA---VDARIINTSSAAGLQGSVGQGN
MLBr_02565|M.leprae_Br4923 ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
* . : *
TH_2904|M.thermoresistible__bu --------------YGVPKAGADKMAADMAVDFREYGIAA--VSIWMGSL
Mflv_1260|M.gilvum_PYR-GCK --------------YGVPKAATDKMAADMAYDFRDVGIAA--VSIWMGSL
MMAR_3513|M.marinum_M --------------YGAQKAGIDKMAADMAVDFHDTGVAT--VSIWMGIL
MUL_2755|M.ulcerans_Agy99 --------------YGAQKAGIDKMAADMAVDFHDTGVAT--VSIWMGIL
MAV_3035|M.avium_104 --------------YGAQKAGVDKMAADMAVDFRGTGVAT--VSIWMGIL
MSMEG_2923|M.smegmatis_MC2_155 --------------YGAQKAGVDKLAADMAVDFRGTSVCT--VSIWMGIL
Mvan_3919|M.vanbaalenii_PYR-1 --------------YGAQKAGVDKMAADMAVDFRGTGVSA--VSIWMGIL
Mb3578c|M.bovis_AF2122/97 --------------YSAAKAGIAALTLVGAAEMRRYGVTVNAIAPAARTR
Rv3548c|M.tuberculosis_H37Rv --------------YSAAKAGIAALTLVGAAEMRRYGVTVNAIAPAARTR
MAB_0608|M.abscessus_ATCC_1997 --------------YAAAKAGIATLTLQAAAEMGRYGITVNAIAPAARTR
MLBr_02565|M.leprae_Br4923 STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVESAAE
. ... : * . . . :
TH_2904|M.thermoresistible__bu LTERVRKIIASKP---EKFGHILDTAETPELTGHVI--------------
Mflv_1260|M.gilvum_PYR-GCK LTDRVRGIIASNP---EKFGRILDTAETPELTGHVI--------------
MMAR_3513|M.marinum_M LTEKLRGAFGQHPDGQLALAKTAEHAETPEFTGYLI--------------
MUL_2755|M.ulcerans_Agy99 LTEKLRGAFGQHPDGQRTLAKTAEHAETPEFTGYLI--------------
MAV_3035|M.avium_104 LTEKLRAAFGADP---AALAATAEHAETPEFTGYVI--------------
MSMEG_2923|M.smegmatis_MC2_155 LTEKLRAAFAGNP---EALAETAKHAETPEFTGRLI--------------
Mvan_3919|M.vanbaalenii_PYR-1 LTDKLRSAFDGSP---EALAAFAEQAETPEFTGHVI--------------
Mb3578c|M.bovis_AF2122/97 MTETVFAEVMAKP--QEG-FDAMAPENVSPLVVWLG--------------
Rv3548c|M.tuberculosis_H37Rv MTETVFAEMMAKP--QEG-FDAMAPENVSPLVVWLG--------------
MAB_0608|M.abscessus_ATCC_1997 MTEAVFAETMAKP--EDGAFDAMAPENVSPLVVWLG--------------
MLBr_02565|M.leprae_Br4923 ALDETANRVGGTTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAGITR
: . . :
TH_2904|M.thermoresistible__bu ------------------------------------------------WA
Mflv_1260|M.gilvum_PYR-GCK ------------------------------------------------WA
MMAR_3513|M.marinum_M ------------------------------------------------DA
MUL_2755|M.ulcerans_Agy99 ------------------------------------------------GA
MAV_3035|M.avium_104 ------------------------------------------------DA
MSMEG_2923|M.smegmatis_MC2_155 ------------------------------------------------DA
Mvan_3919|M.vanbaalenii_PYR-1 ------------------------------------------------DA
Mb3578c|M.bovis_AF2122/97 ------------------------------------------------SA
Rv3548c|M.tuberculosis_H37Rv ------------------------------------------------SA
MAB_0608|M.abscessus_ATCC_1997 ------------------------------------------------SP
MLBr_02565|M.leprae_Br4923 DKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSISKGGRVIVLSSMAG
TH_2904|M.thermoresistible__bu LYRDPG--LMSVSGQTLIGAELAARYGIRDEDGRRPPSYR-----DLFGV
Mflv_1260|M.gilvum_PYR-GCK LHQDPE--VMALSGQTLIGAELAVKYGIRDEGDRQPPSYR-----EMFDV
MMAR_3513|M.marinum_M LYRDPA--LGELSGQTVIGAELAERYGITDEGGRRPPSHR-----HMLGA
MUL_2755|M.ulcerans_Agy99 LYRDPA--LGELSGQTVIGAELAERYGITDEGGRRPPSHR-----HILGA
MAV_3035|M.avium_104 LFDDPG--LAELSGQTLIGAELAQRYGITDEGGRRPPSHR-----DMLGS
MSMEG_2923|M.smegmatis_MC2_155 LYRDPQ--LGELSGQTVIGAELATRYGITDEGGRIPPSHR-----EMLGA
Mvan_3919|M.vanbaalenii_PYR-1 LFRDPE--LDDVSGHTLIAAELATRYGITDEGGRTPPSHR-----QMLGA
Mb3578c|M.bovis_AF2122/97 ESRDVTGKVFEVEGGIIRVAEGWAHGPQVDKGVKWDPAELGPVVSDLLAK
Rv3548c|M.tuberculosis_H37Rv ESRDVTGKVFEVEGGIIRVAEGWAHGPQVDKGVKWDPAELGPVVSDLLAK
MAB_0608|M.abscessus_ATCC_1997 ESREVTGKVFEVEAGIIRVAEGWAHGPQVDKGARWDPSELGPVVTDLLDK
MLBr_02565|M.leprae_Br4923 IAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPGFIETQMTAA
: : ::. . .:
TH_2904|M.thermoresistible__bu HPRRQYGYMMR---------------------------------------
Mflv_1260|M.gilvum_PYR-GCK HPPAQCAHVMR---------------------------------------
MMAR_3513|M.marinum_M -PRTPSTVVVR---------------------------------------
MUL_2755|M.ulcerans_Agy99 -PRTPSTVVVR---------------------------------------
MAV_3035|M.avium_104 -PRTPSSVVVR---------------------------------------
MSMEG_2923|M.smegmatis_MC2_155 -PRVAHPAVVR---------------------------------------
Mvan_3919|M.vanbaalenii_PYR-1 -PREPSPVIIR---------------------------------------
Mb3578c|M.bovis_AF2122/97 -SRPPVPVYGA---------------------------------------
Rv3548c|M.tuberculosis_H37Rv -SRPPVPVYGA---------------------------------------
MAB_0608|M.abscessus_ATCC_1997 -ARTPVPVYGSQG-------------------------------------
MLBr_02565|M.leprae_Br4923 IPLATREVGRRLNSLLQGGLPVDVAETIAYFAIPASNAVTGNVIRVCGQA
.
TH_2904|M.thermoresistible__bu ----
Mflv_1260|M.gilvum_PYR-GCK ----
MMAR_3513|M.marinum_M ----
MUL_2755|M.ulcerans_Agy99 ----
MAV_3035|M.avium_104 ----
MSMEG_2923|M.smegmatis_MC2_155 ----
Mvan_3919|M.vanbaalenii_PYR-1 ----
Mb3578c|M.bovis_AF2122/97 ----
Rv3548c|M.tuberculosis_H37Rv ----
MAB_0608|M.abscessus_ATCC_1997 ----
MLBr_02565|M.leprae_Br4923 MLGA