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VSHKRLAGKTALITGGTSGIGLATARLFAAEGAKVAVIGRDADRVQATQDELGDGSLALRADTTSPDDMT AVAGRIQDAFGGLDVFFANAGIAYPTPLLETDEQRYDEIMDINIKGVFFSMQAVAPILRDGASVILNTSF LNQVGRPGLSLLSASKAAVRSFARTWSAELLDRGIRVNAISPGAIDTPLQRRGRTPEEAQAVLAALVART PAGRAGAADDIAQAALYLAGDESTFILGAELVVDGGISQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3367 | - | - | 100% (250) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 4e-51 | 45.53% (246) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_5802 | - | 9e-49 | 42.28% (246) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 4e-34 | 32.16% (255) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 2e-36 | 36.73% (245) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1941 | - | 4e-34 | 32.16% (255) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-27 | 31.95% (241) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 5e-36 | 39.76% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_0587 | - | 6e-50 | 43.32% (247) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1242 | - | 2e-45 | 39.68% (247) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3693 | - | 2e-38 | 36.73% (245) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0336 | - | 4e-34 | 36.51% (252) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 3e-54 | 46.12% (245) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1242|M.avium_104 ---------------MGKLDGKVAVITGGSSGLALATAKLFVDEGAHVFI
Mvan_1616|M.vanbaalenii_PYR-1 ---------------MGTLEGKTAVVTGASSGIGLAAAQRLADEGAHVFI
MMAR_0587|M.marinum_M ---------------MGQLEGKTALVTGGNSGIGLAAAQRLAAEGAHVFL
MSMEG_3367|M.smegmatis_MC2_155 -------------MSHKRLAGKTALITGGTSGIGLATARLFAAEGAKVAV
Mb1976|M.bovis_AF2122/97 -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -------------MNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Mflv_4369|M.gilvum_PYR-GCK ---------------MSLLTGQTAVITGGAQGLGFAIAQRFVDEGARVVL
TH_3693|M.thermoresistible__bu ---------------VSLLAGQTAVVTGGARGLGYAIAERFIAEGARVVI
MUL_0336|M.ulcerans_Agy99 --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAV
: .: ::**. *:. . . : * .*
MAV_1242|M.avium_104 TGRRRHALDEAVASIG-----RNVTAVQGDAANLDDLDRLFDTVKREKGS
Mvan_1616|M.vanbaalenii_PYR-1 TGRKKPALDAAAASLG-----SAATAVVGDIARAADLDQLYDAVRARGRG
MMAR_0587|M.marinum_M TGRNQATIDAAVASIG-----SRAHGIRADVSNIEDLARVADAIAAAGRG
MSMEG_3367|M.smegmatis_MC2_155 IGRDADRVQATQDELG-----DGSLALRADTTSPDDMTAVAGRIQDAFGG
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIG----CG-AAACRVDVSDEQQIIAMVDACVAAFGG
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIG----CG-AAACRVDVSDEQQIIAMVDACVAAFGG
Mflv_4369|M.gilvum_PYR-GCK GDVNLEATQEAAEKLG---GADVAHAVRCDVTSSAEVDALVAAAVDTFGA
TH_3693|M.thermoresistible__bu GDIDESATRAAADSLG---GADVAVGMRCDVTRSDEVEALVGAAVKRFGS
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAALG----AD-AMFCRTDVSQPEQVAAVVAAAVDNFGG
MLBr_01807|M.leprae_Br4923 THRAS------------VV-PDWFFGVECDVTDNDAIGAAFKAVEEHQGP
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELG-AGNVIGVRLDVSDPGSCADAARTVVDAFGA
* :
MAV_1242|M.avium_104 IDILFASAGTGGQARRLGEITE-QDFDTVFGLNTRATLFTVQKALPLFND
Mvan_1616|M.vanbaalenii_PYR-1 LDVLFANAGLAVLG-PLAQATE-ADYEQNFDVNVRGTWLTVQKAAPLLND
MMAR_0587|M.marinum_M LDVLFANAG-GGEFVLLGDITI-EHFTNGFMTNVAGTLFTVQTMLPLLNS
MSMEG_3367|M.smegmatis_MC2_155 LDVFFANAGIAYPT-PLLETDE-QRYDEIMDINIKGVFFSMQAVAPILRD
Mb1976|M.bovis_AF2122/97 VDKLVANAGVVHLASLIDTTVE--DFDRVIAINLRGAWLCTKHAAPRMIE
Rv1941|M.tuberculosis_H37Rv VDKLVANAGVVHLASLIDTTVE--DFDRVIAINLRGAWLCTKHAAPRMIE
Mflv_4369|M.gilvum_PYR-GCK LDIMVNNAGITRDATMRKMTED--DFDKVIAVHLKGTWNGLRAAAAIMRE
TH_3693|M.thermoresistible__bu LDVMVNNAGITRDATMRKMTEQ--QFDEVIAVHLKGTWNGLRAAAAIMRE
MUL_0336|M.ulcerans_Agy99 LHVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAA
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEE--QFQKVIDVNLTGVFRVAKLASRNMIK
MAB_0952|M.abscessus_ATCC_1997 LDVVCANAGIFPEARLDTMTPE--QLSEVLDVNVKGTVYTVQACLAPLTA
:. . .** : : .. : :
MAV_1242|M.avium_104 --GGSILMTGSIAS-VKGWPDYSVYSASKAALRSFARTWLNELKDRRIRV
Mvan_1616|M.vanbaalenii_PYR-1 --GASVIVNSSIRA-DDGWENFGLYSASKAAVRSLARTWANELKDRGIRV
MMAR_0587|M.marinum_M --GASIVLTGSTAA-YNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRV
MSMEG_3367|M.smegmatis_MC2_155 --GASVILNTSFLN-QVGRPGLSLLSASKAAVRSFARTWSAELLDRGIRV
Mb1976|M.bovis_AF2122/97 RGGGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRS
Rv1941|M.tuberculosis_H37Rv RGGGAIVNLSSLAG-QVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRS
Mflv_4369|M.gilvum_PYR-GCK NKRGVIVNMSSISG-KVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVRV
TH_3693|M.thermoresistible__bu QKRGAIVNMSSISG-KVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRV
MUL_0336|M.ulcerans_Agy99 HGGGSIVNLTSIGG-IQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRV
MLBr_01807|M.leprae_Br4923 QRFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITA
MAB_0952|M.abscessus_ATCC_1997 SGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTV
. : * . :*.. : : ** :
MAV_1242|M.avium_104 NVLSPGQVATPIQEKMFD-------AETKRQFESLIPR----GTMGRPEE
Mvan_1616|M.vanbaalenii_PYR-1 NTVSPGAIDTPAVDKVVD-------PEVASAFKAELVKGVPIGRLGRPEE
MMAR_0587|M.marinum_M NTVVPGPVETPGLKGLAP-------EGQEQQLLEGEAAKVPMGRLGKPAE
MSMEG_3367|M.smegmatis_MC2_155 NAISPGAIDTPLQRRGRT-------PEEAQAVLAALVARTPAGRAGAADD
Mb1976|M.bovis_AF2122/97 NTLLPAFVDTPMQQTAMAMFD----GALGAGGARSMIAR-LQGRMAAPEE
Rv1941|M.tuberculosis_H37Rv NTLLPAFVDTPMQQTAMAMFD----GALGAGGARSMIAR-LQGRMAAPEE
Mflv_4369|M.gilvum_PYR-GCK NAIQPG-----LIRSAMT-------EAMPQRIWDSKVAEVPLGRAGEPDE
TH_3693|M.thermoresistible__bu NAIQPG-----LIRSAMT-------EAMPQRIWDEKLAEIPMGRAGEPEE
MUL_0336|M.ulcerans_Agy99 NAIAPGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPED
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMTRAMDS------------KYQEAALQAIPLGRIGAVEE
MAB_0952|M.abscessus_ATCC_1997 NAILPGNILTEGLVDMGE------------EYISGMARSIPMGMLGSPVD
*.: *. . :
MAV_1242|M.avium_104 IATAALFLASDDSSYVNGVELAVDGGTSAI--------
Mvan_1616|M.vanbaalenii_PYR-1 VAAAVAFLASADSSFIYGANLDIDGGEHQV--------
MMAR_0587|M.marinum_M IAAAVLFLASDQSSFMTGSEMFVDGGTEQL--------
MSMEG_3367|M.smegmatis_MC2_155 IAQAALYLAGDESTFILGAELVVDGGISQL--------
Mb1976|M.bovis_AF2122/97 MAGIVVFLLSDDASMITGTTQIADGGTIAALW------
Rv1941|M.tuberculosis_H37Rv MAGIVVFLLSDDASMITGTTQIADGGTIAALW------
Mflv_4369|M.gilvum_PYR-GCK VAKVALFLASDLSSYMTGTVLEVTGGRHL---------
TH_3693|M.thermoresistible__bu VAKVALFLASDLSSYMTGTVLEVTGGRHL---------
MUL_0336|M.ulcerans_Agy99 IAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-
MLBr_01807|M.leprae_Br4923 IAGAVSFLASEDAGYISGAVIPVDGGLGMGH-------
MAB_0952|M.abscessus_ATCC_1997 IGHLAAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP
:. . :: : : * **