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GTLEGKTAVVTGASSGIGLAAAQRLADEGAHVFITGRKKPALDAAAASLGSAATAVVGDIARAADLDQLY DAVRARGRGLDVLFANAGLAVLGPLAQATEADYEQNFDVNVRGTWLTVQKAAPLLNDGASVIVNSSIRAD DGWENFGLYSASKAAVRSLARTWANELKDRGIRVNTVSPGAIDTPAVDKVVDPEVASAFKAELVKGVPIG RLGRPEEVAAAVAFLASADSSFIYGANLDIDGGEHQV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | - | 100% (248) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | 2e-32 | 35.74% (249) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1975 | fabG | 7e-32 | 36.44% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 8e-38 | 39.02% (246) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 2e-33 | 36.84% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1941 | - | 8e-38 | 39.02% (246) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 6e-25 | 31.25% (240) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0073c | - | 1e-32 | 39.92% (263) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_0587 | - | 1e-63 | 52.38% (252) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1242 | - | 1e-65 | 51.43% (245) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 3e-60 | 52.42% (248) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3969 | - | 4e-33 | 35.08% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2885 | - | 1e-34 | 37.14% (245) | short-chain type dehydrogenase/reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1616|M.vanbaalenii_PYR-1 ------------------------------MGTLEGKTAVVTGASSGIGL
MAV_1242|M.avium_104 ------------------------------MGKLDGKVAVITGGSSGLAL
MMAR_0587|M.marinum_M ------------------------------MGQLEGKTALVTGGNSGIGL
MSMEG_6823|M.smegmatis_MC2_155 ------------------------------MGQLDGKTALVTGGTSGIGH
Mflv_4369|M.gilvum_PYR-GCK ------------------------------MSLLTGQTAVITGGAQGLGF
MLBr_01807|M.leprae_Br4923 ---------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGL
Mb1976|M.bovis_AF2122/97 ----------------------------MNHPDLAGKVAIVTGAGAGIGL
Rv1941|M.tuberculosis_H37Rv ----------------------------MNHPDLAGKVAIVTGAGAGIGL
MUL_2885|M.ulcerans_Agy99 ----------------------------MRYPDLAGKATIVTGAGAGIGL
MAB_0073c|M.abscessus_ATCC_199 ------------------------------MTRLGGRVAVVTGAGKGMGR
TH_3969|M.thermoresistible__bu MGFPEQQQQVPGRQSAMDPVPDCGESSYRGSGKLTGKRAVITGGDSGIGR
: .: ::**. *:.
Mvan_1616|M.vanbaalenii_PYR-1 AAAQRLADEGAHVFITGRKK--PALDAAAASLGSA--ATAVVGDIARAAD
MAV_1242|M.avium_104 ATAKLFVDEGAHVFITGRRR--HALDEAVASIGRN--VTAVQGDAANLDD
MMAR_0587|M.marinum_M AAAQRLAAEGAHVFLTGRNQ--ATIDAAVASIGSR--AHGIRADVSNIED
MSMEG_6823|M.smegmatis_MC2_155 AAAKRLVQEGAYVFITGRDR--TRAEKAAASIG----AHGVQSDVSNPDE
Mflv_4369|M.gilvum_PYR-GCK AIAQRFVDEGARVVLGDVNL--EATQEAAEKLGGADVAHAVRCDVTSSAE
MLBr_01807|M.leprae_Br4923 AVARRLVADGHRVAVTHR-----ASVVPDWFFG-------VECDVTDNDA
Mb1976|M.bovis_AF2122/97 AVARRLADEGCHVLCADIDG--DAADAAATKIGCG--AAACRVDVSDEQQ
Rv1941|M.tuberculosis_H37Rv AVARRLADEGCHVLCADIDG--DAADAAATKIGCG--AAACRVDVSDEQQ
MUL_2885|M.ulcerans_Agy99 AIAERLAAEGAAVLCADIDG--ASAEQAAAKIGSG--AVGYQVDVSAEEQ
MAB_0073c|M.abscessus_ATCC_199 THCERLAEEGSDVIAIDLPGSDDLAQTAAAVEEHGRRCVWAFADVRDAAA
TH_3969|M.thermoresistible__bu AVAIAYAREGADVLVSYLNEDDDAAEVAQLVTDAGRRCVLVPGDLSDPAH
: . . :* * . *
Mvan_1616|M.vanbaalenii_PYR-1 LDQLYDAVRARGRGLDVLFANAGLAVLG-PLAQATEADYEQNFDVNVRGT
MAV_1242|M.avium_104 LDRLFDTVKREKGSIDILFASAGTGGQARRLGEITEQDFDTVFGLNTRAT
MMAR_0587|M.marinum_M LARVADAIAAAGRGLDVLFANAGGGEFV-LLGDITIEHFTNGFMTNVAGT
MSMEG_6823|M.smegmatis_MC2_155 LDALAAEIAEYGKGLDVVFANAGGGDYA-TLAEVTPQHYRDNIDRNVGGT
Mflv_4369|M.gilvum_PYR-GCK VDALVAAAVDTFGALDIMVNNAGITR-DATMRKMTEDDFDKVIAVHLKGT
MLBr_01807|M.leprae_Br4923 IGAAFKAVEEHQGPVEVLVANAGITS-DMLIMRMSEEQFQKVIDVNLTGV
Mb1976|M.bovis_AF2122/97 IIAMVDACVAAFGGVDKLVANAGVVH-LASLIDTTVEDFDRVIAINLRGA
Rv1941|M.tuberculosis_H37Rv IIAMVDACVAAFGGVDKLVANAGVVH-LASLIDTTVEDFDRVIAINLRGA
MUL_2885|M.ulcerans_Agy99 VAGMVEACVTSFGGLDKLVANAGVVH-LAPILDTAVEDFDRVIGINLRGA
MAB_0073c|M.abscessus_ATCC_199 LTEAIDTGVRMLGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGA
TH_3969|M.thermoresistible__bu CRSVIDRAVSEFDGLDVLVVNHAHQMTHPTLEEISDEEWDYTFRLNIGAY
:: :. . . : : : : .
Mvan_1616|M.vanbaalenii_PYR-1 WLTVQKAAPLLND--GASVIVNSSIRADDGWENFGLYSASKAAVRSLART
MAV_1242|M.avium_104 LFTVQKALPLFND--GGSILMTGSIASVKGWPDYSVYSASKAALRSFART
MMAR_0587|M.marinum_M LFTVQTMLPLLNS--GASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRT
MSMEG_6823|M.smegmatis_MC2_155 VFTVQKILPLLND--GASIILTGSTAPAKGTPAFGLYAASKAAIRSLGRT
Mflv_4369|M.gilvum_PYR-GCK WNGLRAAAAIMRENKRGVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKA
MLBr_01807|M.leprae_Br4923 FRVAKLASRNMIKQRFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARS
Mb1976|M.bovis_AF2122/97 WLCTKHAAPRMIERGGGAIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRI
Rv1941|M.tuberculosis_H37Rv WLCTKHAAPRMIERGGGAIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRI
MUL_2885|M.ulcerans_Agy99 WLCTKHAAPKMVERGGGAIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRV
MAB_0073c|M.abscessus_ATCC_199 WHTVKAGAAHLLD--GGSVIIISSTNGLKGTANTAHYTASKHAVVGLART
TH_3969|M.thermoresistible__bu FHLVKAALPHLKP--GASIIGSSSVNSDMPSPTLAPYAATKAAIANFSAS
: : . : .* * :* .: :
Mvan_1616|M.vanbaalenii_PYR-1 WANELKDRGIRVNTVSPGAIDT----PAVDKVVDPEVASAFKAELVKGVP
MAV_1242|M.avium_104 WLNELKDRRIRVNVLSPGQVAT----PIQEKMFDAETKRQFESLIPR---
MMAR_0587|M.marinum_M WAAELVSRNIRVNTVVPGPVET----PGLKGLAPEGQEQQLLEGEAAKVP
MSMEG_6823|M.smegmatis_MC2_155 WAAELVDRNIRVNTVIPGPIRT----PGLEGLAPDGQRE--LDGWAAQVP
Mflv_4369|M.gilvum_PYR-GCK ASKELAYLGVRVNAIQPGLIRS--AMTEAMPQRIWDSK-------VAEVP
MLBr_01807|M.leprae_Br4923 LARELGSRSITANVVAPGFIDT--EMTRAMDSKYQEAA-------LQAIP
Mb1976|M.bovis_AF2122/97 TAAELRSSGIRSNTLLPAFVDT--PMQQTAMAMFDGALGAGGARSMIARL
Rv1941|M.tuberculosis_H37Rv TAAELRSSGIRSNTLLPAFVDT--PMQQTAMAMFDGALGAGGARSMIARL
MUL_2885|M.ulcerans_Agy99 TAAELRSANVRSNALLPAFVDT--PMQQSAMAMFDEVLGTGGANTMIARL
MAB_0073c|M.abscessus_ATCC_199 AANELGPQGIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEAL
TH_3969|M.thermoresistible__bu LAQMLGDKGIRVNSVAPGPIWT--------PLIPSTMPPEKVARFGDDTP
* : * : *. : :
Mvan_1616|M.vanbaalenii_PYR-1 IGRLGRPE------EVAAAVAFLASADSSFIYGANLDIDGGEHQV--
MAV_1242|M.avium_104 -GTMGRPE------EIATAALFLASDDSSYVNGVELAVDGGTSAI--
MMAR_0587|M.marinum_M MGRLGKPA------EIAAAVLFLASDQSSFMTGSEMFVDGGTEQL--
MSMEG_6823|M.smegmatis_MC2_155 MKRLGDPD------EIATAVLFLASNQSSFMTGAELVVDGGQIQI--
Mflv_4369|M.gilvum_PYR-GCK LGRAGEPD------EVAKVALFLASDLSSYMTGTVLEVTGGRHL---
MLBr_01807|M.leprae_Br4923 LGRIGAVE------EIAGAVSFLASEDAGYISGAVIPVDGGLGMGH-
Mb1976|M.bovis_AF2122/97 QGRMAAPE------EMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Rv1941|M.tuberculosis_H37Rv QGRMAAPE------EMAGIVVFLLSDDASMITGTTQIADGGTIAALW
MUL_2885|M.ulcerans_Agy99 QGRMARPE------EMARIVAFLLPDDSSMITGTTQIADGGTIAALW
MAB_0073c|M.abscessus_ATCC_199 AARTLLPVPWVEAVDISNAVVFLASDEARYITGTQLVVDAGLTQKA-
TH_3969|M.thermoresistible__bu LGRAGQPA------ELAGAYVLLAADEGSYISGARIAVTGGRPIL--
::: :* . . : * .*