For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GQLDGKTALVTGGTSGIGHAAAKRLVQEGAYVFITGRDRTRAEKAAASIGAHGVQSDVSNPDELDALAAE IAEYGKGLDVVFANAGGGDYATLAEVTPQHYRDNIDRNVGGTVFTVQKILPLLNDGASIILTGSTAPAKG TPAFGLYAASKAAIRSLGRTWAAELVDRNIRVNTVIPGPIRTPGLEGLAPDGQRELDGWAAQVPMKRLGD PDEIATAVLFLASNQSSFMTGAELVVDGGQIQI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6823 | - | - | 100% (244) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_3367 | - | 4e-51 | 45.53% (246) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_5802 | - | 1e-49 | 44.53% (247) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0950c | - | 5e-29 | 35.74% (249) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 6e-37 | 39.27% (247) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv0927c | - | 5e-29 | 35.74% (249) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-24 | 32.91% (237) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 1e-37 | 39.44% (251) | short chain dehydrogenase |
| M. marinum M | MMAR_0587 | - | 6e-87 | 64.92% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1242 | - | 3e-56 | 48.36% (244) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2488 | - | 1e-35 | 37.50% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1037 | fabG3 | 5e-32 | 38.06% (247) | 20-beta-hydroxysteroid dehydrogenase FabG3 |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 3e-60 | 52.42% (248) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1235|M.gilvum_PYR-GCK ------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAG-------
MAB_0952|M.abscessus_ATCC_1997 MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAG-------
Mb0950c|M.bovis_AF2122/97 ---------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAG-------
Rv0927c|M.tuberculosis_H37Rv ---------MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAG-------
MSMEG_6823|M.smegmatis_MC2_155 -------------MGQLDGKTALVTGGTSGIGHAAAKRLVQEG-------
MMAR_0587|M.marinum_M -------------MGQLEGKTALVTGGNSGIGLAAAQRLAAEG-------
MAV_1242|M.avium_104 -------------MGKLDGKVAVITGGSSGLALATAKLFVDEG-------
Mvan_1616|M.vanbaalenii_PYR-1 -------------MGTLEGKTAVVTGASSGIGLAAAQRLADEG-------
TH_2488|M.thermoresistible__bu --------------MEFQGLHVLVTGGTGGIGLACARAFAEAG-------
MLBr_01807|M.leprae_Br4923 -------------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAV
MUL_1037|M.ulcerans_Agy99 -------------MGRVDGKVALISGGARGMGASHARLLVQEG-------
.* . : .. .
Mflv_1235|M.gilvum_PYR-GCK INVVITARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAIE
MAB_0952|M.abscessus_ATCC_1997 ANVAVAARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVD
Mb0950c|M.bovis_AF2122/97 ADVLIASRTSSELDAVAEQIRAA-GRRAHTVAADLAHPEVTAQLAGQAVG
Rv0927c|M.tuberculosis_H37Rv ADVLIASRTSSELDAVAEQIRAA-GRRAHTVAADLAHPEVTAQLAGQAVG
MSMEG_6823|M.smegmatis_MC2_155 AYVFITGRDRTRAEKAAASIG------AHGVQSDVSNPDELDALAAEIAE
MMAR_0587|M.marinum_M AHVFLTGRNQATIDAAVASIGSR----AHGIRADVSNIEDLARVADAIAA
MAV_1242|M.avium_104 AHVFITGRRRHALDEAVASIGRN----VTAVQGDAANLDDLDRLFDTVKR
Mvan_1616|M.vanbaalenii_PYR-1 AHVFITGRKKPALDAAAASLGSA----ATAVVGDIARAADLDQLYDAVRA
TH_2488|M.thermoresistible__bu AEVTVTGRD-AGRGAAAAGAHPR----LRFIRGDLA---DLASVQNLIR-
MLBr_01807|M.leprae_Br4923 ARRLVADGHRVAVTHRASVVPDW----FFGVECDVTDNDAIGAAFKAVEE
MUL_1037|M.ulcerans_Agy99 AKVVIGDILDEEGKALAEEIGDA----ARYVHLDVTQPDQWEAAVATAVD
: . : * :
Mflv_1235|M.gilvum_PYR-GCK RHGGLDIVCPNAG-IFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDA
MAB_0952|M.abscessus_ATCC_1997 AFGALDVVCANAG-IFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAP
Mb0950c|M.bovis_AF2122/97 AFGKLDIVVNNVG-GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPL
Rv0927c|M.tuberculosis_H37Rv AFGKLDIVVNNVG-GTMPNTLLSTSTKDLADAFAFNVGTAHALTVAAVPL
MSMEG_6823|M.smegmatis_MC2_155 YGKGLDVVFANAG-GGDYATLAEVTPQHYRDNIDRNVGGTVFTVQKILP-
MMAR_0587|M.marinum_M AGRGLDVLFANAG-GGEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLP-
MAV_1242|M.avium_104 EKGSIDILFASAGTGGQARRLGEITEQDFDTVFGLNTRATLFTVQKALP-
Mvan_1616|M.vanbaalenii_PYR-1 RGRGLDVLFANAGLAVLG-PLAQATEADYEQNFDVNVRGTWLTVQKAAP-
TH_2488|M.thermoresistible__bu YADAVDVLVNNAA-SFPGALTVEQDAESFTRTFATNVTGTYFLTAGLIPG
MLBr_01807|M.leprae_Br4923 HQGPVEVLVANAG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRN
MUL_1037|M.ulcerans_Agy99 EFGKLDVLVNNVG-IVALGQLKKFDLGKWQKVIDVNLTGTFLGMRAAVEP
:::: ... : * .
Mflv_1235|M.gilvum_PYR-GCK LTASGHGRVIITSSITGPITGFPGWSHYGASKAAQLGFLRTAAIELAPKK
MAB_0952|M.abscessus_ATCC_1997 LTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRG
Mb0950c|M.bovis_AF2122/97 MLEHSGGGSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-
Rv0927c|M.tuberculosis_H37Rv MLEHSGGGSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCPR-
MSMEG_6823|M.smegmatis_MC2_155 LLNDG--ASIILTGSTAPAKGTPAFGLYAASKAAIRSLGRTWAAELVDRN
MMAR_0587|M.marinum_M LLNSG--ASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRTWAAELVSRN
MAV_1242|M.avium_104 LFNDG--GSILMTGSIASVKGWPDYSVYSASKAALRSFARTWLNELKDRR
Mvan_1616|M.vanbaalenii_PYR-1 LLNDG--ASVIVNSSIRADDGWENFGLYSASKAAVRSLARTWANELKDRG
TH_2488|M.thermoresistible__bu MLARGR-GSIVNITSMVATKAVPGASVYSSSKAAVESLTRSWAVEFAAHG
MLBr_01807|M.leprae_Br4923 MIKQRF-GRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRS
MUL_1037|M.ulcerans_Agy99 MTAAGS-GSIINVSSIEGLRGAPAVHPYVASKWAVRGLTKSAALELAPLN
: : . * ::* . : ::
Mflv_1235|M.gilvum_PYR-GCK ITVNAVLPGNILTEGLVEMGQSYIDQ-----MAAAVPAGKLGEVADIGNA
MAB_0952|M.abscessus_ATCC_1997 VTVNAILPGNILTEGLVDMGEEYISG-----MARSIPMGMLGSPVDIGHL
Mb0950c|M.bovis_AF2122/97 VRVNAIAPGSILTSALEVVAANDELR---APMEQATPLRRLGDPVDIAAA
Rv0927c|M.tuberculosis_H37Rv VRVNAIAPGSILTSALEVVAANDELR---APMEQATPLRRLGDPVDIAAA
MSMEG_6823|M.smegmatis_MC2_155 IRVNTVIPGPIRTPGLEGLAPDGQRE--LDGWAAQVPMKRLGDPDEIATA
MMAR_0587|M.marinum_M IRVNTVVPGPVETPGLKGLAPEGQEQQLLEGEAAKVPMGRLGKPAEIAAA
MAV_1242|M.avium_104 IRVNVLSPGQVATPIQEKMFDAETKRQFESLIPR----GTMGRPEEIATA
Mvan_1616|M.vanbaalenii_PYR-1 IRVNTVSPGAIDTPAVDKVVDPEVASAFKAELVKGVPIGRLGRPEEVAAA
TH_2488|M.thermoresistible__bu IRVNAVAPGPTSTDGVATEWGETN-----EALGRALPIGRTADPDEIAQA
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTRAMDSKYQE-----AALQAIPLGRIGAVEEIAGA
MUL_1037|M.ulcerans_Agy99 IRVNSIHPGFIRTPMTANLP----------DDMVTIPLGRPAESREVSTF
: .* : ** * . ::.
Mflv_1235|M.gilvum_PYR-GCK ALFFATDEAAYITGQSLVVDGGQILPESPEALADL
MAB_0952|M.abscessus_ATCC_1997 AAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP-
Mb0950c|M.bovis_AF2122/97 AVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL
Rv0927c|M.tuberculosis_H37Rv AVYLASPAGSFLTGKTLEVDGGLTFPNLDLPIPDL
MSMEG_6823|M.smegmatis_MC2_155 VLFLASNQSSFMTGAELVVDGGQIQI---------
MMAR_0587|M.marinum_M VLFLASDQSSFMTGSEMFVDGGTEQL---------
MAV_1242|M.avium_104 ALFLASDDSSYVNGVELAVDGGTSAI---------
Mvan_1616|M.vanbaalenii_PYR-1 VAFLASADSSFIYGANLDIDGGEHQV---------
TH_2488|M.thermoresistible__bu VVFLASSRASFITGAVLHVDGGGIAV---------
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH--------
MUL_1037|M.ulcerans_Agy99 VVFLASDDASYATGSEFVMDGGLVTDVPHKQF---
. ::*: ..: * : :***