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MARLTDKTALVIGGARGLGHAIAERFTDEGAETYVTSRSRTDLEEAVEVIGAGAHAVVADPNRRADLVAA VEVIRARSGHLDVLVVNAGTGEPAGLDKITEDHVDRIVGLNVRSLLFAVQSALPLMGPGGSIILIGSAAG DMGFPGFSVYAATKAAVRSFARTWTLELAPRAIRVNVISPGPIDTAMHRRASEEVRQWLVSHVPLGRAGR PEEVAAAALFLAADESSFVAGVDLGVDGGMAQV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5802 | - | - | 100% (243) | oxidoreductase, short chain dehydrogenase/reductase family protein |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 1e-49 | 44.53% (247) | short-chain dehydrogenase/reductase SDR |
| M. smegmatis MC2 155 | MSMEG_3367 | - | 8e-49 | 42.28% (246) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 9e-33 | 35.00% (240) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 1e-38 | 38.75% (240) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1350 | fabG | 1e-32 | 35.00% (240) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-29 | 31.36% (236) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 6e-34 | 37.35% (249) | short chain dehydrogenase |
| M. marinum M | MMAR_0587 | - | 5e-54 | 47.18% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1242 | - | 3e-56 | 46.94% (245) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3693 | - | 7e-36 | 37.08% (240) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 2e-34 | 35.90% (234) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 4e-51 | 45.97% (248) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 --------------MASLLNAR---TAVITGGAQGLGLAIGQRFVAEGAR
Rv1350|M.tuberculosis_H37Rv --------------MASLLNAR---TAVITGGAQGLGLAIGQRFVAEGAR
MUL_3898|M.ulcerans_Agy99 --------------MCGAHRDRGYVYPVVTGGAQGLGLAIAERFVSEGAR
Mflv_4369|M.gilvum_PYR-GCK ---------------MSLLTGQ---TAVITGGAQGLGFAIAQRFVDEGAR
TH_3693|M.thermoresistible__bu ---------------VSLLAGQ---TAVVTGGARGLGYAIAERFIAEGAR
MAV_1242|M.avium_104 ---------------MGKLDGK---VAVITGGSSGLALATAKLFVDEGAH
Mvan_1616|M.vanbaalenii_PYR-1 ---------------MGTLEGK---TAVVTGASSGIGLAAAQRLADEGAH
MMAR_0587|M.marinum_M ---------------MGQLEGK---TALVTGGNSGIGLAAAQRLAAEGAH
MSMEG_5802|M.smegmatis_MC2_155 ---------------MARLTDK---TALVIGGARGLGHAIAERFTDEGAE
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSAR---SVLVTGGTKGIGRGIATVFARAGAN
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSR---SILVTGGNRGIGLAVARRLVADGHR
: :: *. *:. . . : * .
Mb1385|M.bovis_AF2122/97 VVLGDVNLEATEVAAKRLGGDD--VALAVRCDVTQADDVDILIRTAVERF
Rv1350|M.tuberculosis_H37Rv VVLGDVNLEATEVAAKRLGGDD--VALAVRCDVTQADDVDILIRTAVERF
MUL_3898|M.ulcerans_Agy99 VVLGDVNLEATEAAAKQLGGGE--VAVAVRCDVTKADEVETLLQAALERF
Mflv_4369|M.gilvum_PYR-GCK VVLGDVNLEATQEAAEKLGGAD--VAHAVRCDVTSSAEVDALVAAAVDTF
TH_3693|M.thermoresistible__bu VVIGDIDESATRAAADSLGGAD--VAVGMRCDVTRSDEVEALVGAAVKRF
MAV_1242|M.avium_104 VFITGRRRHALDEAVASIGRN----VTAVQGDAANLDDLDRLFDTVKREK
Mvan_1616|M.vanbaalenii_PYR-1 VFITGRKKPALDAAAASLGSA----ATAVVGDIARAADLDQLYDAVRARG
MMAR_0587|M.marinum_M VFLTGRNQATIDAAVASIGSR----AHGIRADVSNIEDLARVADAIAAAG
MSMEG_5802|M.smegmatis_MC2_155 TYVTSRSRTDLEEAVEVIGAG----AHAVVADPNRRADLVAAVEVIRARS
MAB_0952|M.abscessus_ATCC_1997 VAVAARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAF
MLBr_01807|M.leprae_Br4923 VAVTHRASVVPDWFFG------------VECDVTDNDAIGAAFKAVEEHQ
. : : * .
Mb1385|M.bovis_AF2122/97 GGLDVMVNNAG-ITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMR
Rv1350|M.tuberculosis_H37Rv GGLDVMVNNAG-ITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAIMR
MUL_3898|M.ulcerans_Agy99 GGLDIMVNNAG-ITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMR
Mflv_4369|M.gilvum_PYR-GCK GALDIMVNNAG-ITRDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMR
TH_3693|M.thermoresistible__bu GSLDVMVNNAG-ITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMR
MAV_1242|M.avium_104 GSIDILFASAGTGGQARRLGEITEQDFDTVFGLNTRATLFTVQKALPLFN
Mvan_1616|M.vanbaalenii_PYR-1 RGLDVLFANAGLAVLG-PLAQATEADYEQNFDVNVRGTWLTVQKAAPLLN
MMAR_0587|M.marinum_M RGLDVLFANAG-GGEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLPLLN
MSMEG_5802|M.smegmatis_MC2_155 GHLDVLVVNAG-TGEPAGLDKITEDHVDRIVGLNVRSLLFAVQSALPLMG
MAB_0952|M.abscessus_ATCC_1997 GALDVVCANAG-IFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLT
MLBr_01807|M.leprae_Br4923 GPVEVLVANAG-ITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
:::: .** : : . . : . : :
Mb1385|M.bovis_AF2122/97 ER-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIR
Rv1350|M.tuberculosis_H37Rv ER-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIR
MUL_3898|M.ulcerans_Agy99 EN-KRGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHVGVR
Mflv_4369|M.gilvum_PYR-GCK EN-KRGVIVNMSSISGKVGMIGQTNYSAAKAGIVGMTKAASKELAYLGVR
TH_3693|M.thermoresistible__bu EQ-KRGAIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVR
MAV_1242|M.avium_104 D---GGSILMTGSIASVKGWPDYSVYSASKAALRSFARTWLNELKDRRIR
Mvan_1616|M.vanbaalenii_PYR-1 D---GASVIVNSSIRADDGWENFGLYSASKAAVRSLARTWANELKDRGIR
MMAR_0587|M.marinum_M S---GASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIR
MSMEG_5802|M.smegmatis_MC2_155 P---GGSIILIGSAAGDMGFPGFSVYAATKAAVRSFARTWTLELAPRAIR
MAB_0952|M.abscessus_ATCC_1997 ASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVT
MLBr_01807|M.leprae_Br4923 KQ-RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSIT
: . * *.*:*:. .: :: ** :
Mb1385|M.bovis_AF2122/97 VNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASVAV
Rv1350|M.tuberculosis_H37Rv VNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASVAV
MUL_3898|M.ulcerans_Agy99 VNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASVAL
Mflv_4369|M.gilvum_PYR-GCK VNAIQPGLIRSAMTEAMP-----QRIWDSKVAEVPLGRAGEPDEVAKVAL
TH_3693|M.thermoresistible__bu VNAIQPGLIRSAMTEAMP-----QRIWDEKLAEIPMGRAGEPEEVAKVAL
MAV_1242|M.avium_104 VNVLSPGQVATPIQEKMFDAETKRQFESLIPR----GTMGRPEEIATAAL
Mvan_1616|M.vanbaalenii_PYR-1 VNTVSPGAIDTPAVDKVVDPEVASAFKAELVKGVPIGRLGRPEEVAAAVA
MMAR_0587|M.marinum_M VNTVVPGPVETPGLKGLAPEGQEQQLLEGEAAKVPMGRLGKPAEIAAAVL
MSMEG_5802|M.smegmatis_MC2_155 VNVISPGPIDT-AMHRRASEEVRQWLVSHVPL----GRAGRPEEVAAAAL
MAB_0952|M.abscessus_ATCC_1997 VNAILPGNILTEGLVDMG-----EEYISGMARSIPMGMLGSPVDIGHLAA
MLBr_01807|M.leprae_Br4923 ANVVAPGFIDTEMTRAMD-----SKYQEAALQAIPLGRIGAVEEIAGAVS
.*.: ** : : * * ::. .
Mb1385|M.bovis_AF2122/97 FLASDLSSYMTGTVLDVTGGRFI---------
Rv1350|M.tuberculosis_H37Rv FLASDLSSYMTGTVLDVTGGRFI---------
MUL_3898|M.ulcerans_Agy99 FLACDLSSYMTGTVLDVTGGRFI---------
Mflv_4369|M.gilvum_PYR-GCK FLASDLSSYMTGTVLEVTGGRHL---------
TH_3693|M.thermoresistible__bu FLASDLSSYMTGTVLEVTGGRHL---------
MAV_1242|M.avium_104 FLASDDSSYVNGVELAVDGGTSAI--------
Mvan_1616|M.vanbaalenii_PYR-1 FLASADSSFIYGANLDIDGGEHQV--------
MMAR_0587|M.marinum_M FLASDQSSFMTGSEMFVDGGTEQL--------
MSMEG_5802|M.smegmatis_MC2_155 FLAADESSFVAGVDLGVDGGMAQV--------
MAB_0952|M.abscessus_ATCC_1997 FLATDEAGYITGQAIVVDGGQVLPESPDAVNP
MLBr_01807|M.leprae_Br4923 FLASEDAGYISGAVIPVDGGLGMGH-------
*** :.:: * : : **