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GKLDGKVAVITGGSSGLALATAKLFVDEGAHVFITGRRRHALDEAVASIGRNVTAVQGDAANLDDLDRLF DTVKREKGSIDILFASAGTGGQARRLGEITEQDFDTVFGLNTRATLFTVQKALPLFNDGGSILMTGSIAS VKGWPDYSVYSASKAALRSFARTWLNELKDRRIRVNVLSPGQVATPIQEKMFDAETKRQFESLIPRGTMG RPEEIATAALFLASDDSSYVNGVELAVDGGTSAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1242 | - | - | 100% (245) | short-chain dehydrogenase/reductase SDR |
| M. avium 104 | MAV_2726 | - | 5e-55 | 47.84% (255) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_0886 | - | 1e-30 | 32.68% (257) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 2e-31 | 35.39% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 2e-33 | 34.43% (244) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 2e-31 | 35.39% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-24 | 31.06% (235) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 3e-29 | 33.33% (246) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_0587 | - | 1e-59 | 47.39% (249) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 3e-56 | 48.36% (244) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3420 | - | 6e-32 | 35.02% (257) | PUTATIVE oxidoreductase, short chain dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0336 | - | 8e-27 | 30.23% (258) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 1e-65 | 51.43% (245) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1242|M.avium_104 ---------------MGKLDGKVAVITGGSSGLALATAKLFVDEGAHVFI
Mvan_1616|M.vanbaalenii_PYR-1 ---------------MGTLEGKTAVVTGASSGIGLAAAQRLADEGAHVFI
MMAR_0587|M.marinum_M ---------------MGQLEGKTALVTGGNSGIGLAAAQRLAAEGAHVFL
MSMEG_6823|M.smegmatis_MC2_155 ---------------MGQLDGKTALVTGGTSGIGHAAAKRLVQEGAYVFI
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MAB_0833|M.abscessus_ATCC_1997 -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
TH_3420|M.thermoresistible__bu -----------VTERAGELAGKVAVVTGGAAGLGAGLARRFVAEGAKVLI
MUL_0336|M.ulcerans_Agy99 --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
Mflv_1235|M.gilvum_PYR-GCK --------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAGINVVI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: :**. *:. . . * * :
MAV_1242|M.avium_104 TGRRRHALDEAVASIGR---NVTAVQGDAANLDDLDRLFDTVKREKGSID
Mvan_1616|M.vanbaalenii_PYR-1 TGRKKPALDAAAASLGS---AATAVVGDIARAADLDQLYDAVRARGRGLD
MMAR_0587|M.marinum_M TGRNQATIDAAVASIGS---RAHGIRADVSNIEDLARVADAIAAAGRGLD
MSMEG_6823|M.smegmatis_MC2_155 TGRDRTRAEKAAASIG-----AHGVQSDVSNPDELDALAAEIAEYGKGLD
Mb2788c|M.bovis_AF2122/97 TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
Rv2766c|M.tuberculosis_H37Rv TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
MAB_0833|M.abscessus_ATCC_1997 ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
TH_3420|M.thermoresistible__bu GDVDTGNGAKLAAELG---ADAEFVEADVADLDQVSGLVSTAVERFGGLH
MUL_0336|M.ulcerans_Agy99 ADVEEERGESLAAALG---ADAMFCRTDVSQPEQVAAVVAAAVDNFGGLH
Mflv_1235|M.gilvum_PYR-GCK TARTQDDIDATVADLAGLAGTVTGVAADVTSPEDCRRVVETAIERHGGLD
MLBr_01807|M.leprae_Br4923 THRASVVPD-----------WFFGVECDVTDNDAIGAAFKAVEEHQGPVE
. :.
MAV_1242|M.avium_104 ILFASAGTGGQAR-RLGEITEQDFDTVFGLNTRATLFTVQKALPLFN--D
Mvan_1616|M.vanbaalenii_PYR-1 VLFANAGLAVLG--PLAQATEADYEQNFDVNVRGTWLTVQKAAPLLN--D
MMAR_0587|M.marinum_M VLFANAGGGEFV--LLGDITIEHFTNGFMTNVAGTLFTVQTMLPLLN--S
MSMEG_6823|M.smegmatis_MC2_155 VVFANAGGGDYA--TLAEVTPQHYRDNIDRNVGGTVFTVQKILPLLN--D
Mb2788c|M.bovis_AF2122/97 ILINNAGTNPAYG-PLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
Rv2766c|M.tuberculosis_H37Rv ILINNAGTNPAYG-PLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGEH
MAB_0833|M.abscessus_ATCC_1997 IVVNNA-ANALTE-PVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVASP
TH_3420|M.thermoresistible__bu VMVNNAGISGTMHRSLLDDDLADFDRVMRINVRAVMAGTRDAARHMAEHG
MUL_0336|M.ulcerans_Agy99 VMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
Mflv_1235|M.gilvum_PYR-GCK IVCPNAGIFPSGR--IADLTPDDIEQVLGVNFKGTVYIVQAALDALTASG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDML--IMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
:: .* . : * . .
MAV_1242|M.avium_104 GGSILMTGSIAS-VKGWPDYSVYSASKAALRSFARTWLNELKDRRIRVNV
Mvan_1616|M.vanbaalenii_PYR-1 GASVIVNSSIRA-DDGWENFGLYSASKAAVRSLARTWANELKDRGIRVNT
MMAR_0587|M.marinum_M GASIVLTGSTAA-YNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRVNT
MSMEG_6823|M.smegmatis_MC2_155 GASIILTGSTAP-AKGTPAFGLYAASKAAIRSLGRTWAAELVDRNIRVNT
Mb2788c|M.bovis_AF2122/97 GGAVVNTASIGG-MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
Rv2766c|M.tuberculosis_H37Rv GGAVVNTASIGG-MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
MAB_0833|M.abscessus_ATCC_1997 HAAVLNVVSVGA-FMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNA
TH_3420|M.thermoresistible__bu GGSIINLTSIGG-IQAGGGVQTYRASKAAVIQFTKSAAIELAHHEIRVNA
MUL_0336|M.ulcerans_Agy99 GGSIVNLTSIGG-IQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNA
Mflv_1235|M.gilvum_PYR-GCK HGRVIITSSITGPITGFPGWSHYGASKAAQLGFLRTAAIELAPKKITVNA
MLBr_01807|M.leprae_Br4923 FGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
. : * * *:*.. : ** : .*.
MAV_1242|M.avium_104 LSPGQVATPIQEKMFD-------AETKRQFESLIPR----GTMGRPEEIA
Mvan_1616|M.vanbaalenii_PYR-1 VSPGAIDTPAVDKVVD-------PEVASAFKAELVKGVPIGRLGRPEEVA
MMAR_0587|M.marinum_M VVPGPVETPGLKGLAP-------EGQEQQLLEGEAAKVPMGRLGKPAEIA
MSMEG_6823|M.smegmatis_MC2_155 VIPGPIRTPGLEGLAP-------DGQRE--LDGWAAQVPMKRLGDPDEIA
Mb2788c|M.bovis_AF2122/97 ICPGVVRTRLAEALWK-------DHEDP-----LAATIALGRIGEPADIA
Rv2766c|M.tuberculosis_H37Rv ICPGVVRTRLAEALWK-------DHEDP-----LAATIALGRIGEPADIA
MAB_0833|M.abscessus_ATCC_1997 LAPGAIDTDMVRKTPP-------AEVER-----MANTNHLKRLGLPDEMV
TH_3420|M.thermoresistible__bu LAPGNIRTAIVRKSATGADLERLERFEARIRQQMRDDRPLKREGTVEDVA
MUL_0336|M.ulcerans_Agy99 IAPGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIA
Mflv_1235|M.gilvum_PYR-GCK VLPGNILT------------EGLVEMGQSYIDQMAAAVPAGKLGEVADIG
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDS------------KYQEAALQAIPLGRIGAVEEIA
: ** : * * ::
MAV_1242|M.avium_104 TAALFLASDDSSYVNGVELAVDGGTSAI-------------
Mvan_1616|M.vanbaalenii_PYR-1 AAVAFLASADSSFIYGANLDIDGGEHQV-------------
MMAR_0587|M.marinum_M AAVLFLASDQSSFMTGSEMFVDGGTEQL-------------
MSMEG_6823|M.smegmatis_MC2_155 TAVLFLASNQSSFMTGAELVVDGGQIQI-------------
Mb2788c|M.bovis_AF2122/97 SAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv SAVAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MAB_0833|M.abscessus_ATCC_1997 GTALLLTSDAGSYITGQTIIADGGLVAR-------------
TH_3420|M.thermoresistible__bu EAALYFAGDRSRYVTGTVLPIDGGTVAGKVIARKSHAE---
MUL_0336|M.ulcerans_Agy99 EAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR------
Mflv_1235|M.gilvum_PYR-GCK NAALFFATDEAAYITGQSLVVDGGQILPESPEALADL----
MLBr_01807|M.leprae_Br4923 GAVSFLASEDAGYISGAVIPVDGGLGMGH------------
:. :. . :: * : ***