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MGQLEGKTALVTGGNSGIGLAAAQRLAAEGAHVFLTGRNQATIDAAVASIGSRAHGIRADVSNIEDLARV ADAIAAAGRGLDVLFANAGGGEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLPLLNSGASIVLTGSTAA YNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRVNTVVPGPVETPGLKGLAPEGQEQQLLEGEAAKVPM GRLGKPAEIAAAVLFLASDQSSFMTGSEMFVDGGTEQL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0587 | - | - | 100% (248) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_2869 | - | 2e-33 | 36.99% (246) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_1952 | fabG | 3e-32 | 36.48% (244) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2788c | fabG | 5e-34 | 37.70% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 5e-37 | 37.65% (247) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv2766c | fabG | 5e-34 | 37.70% (244) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 7e-26 | 32.37% (241) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 1e-34 | 37.05% (251) | short chain dehydrogenase |
| M. avium 104 | MAV_2726 | - | 2e-61 | 50.59% (253) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6823 | - | 6e-87 | 64.92% (248) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2488 | - | 2e-38 | 42.11% (247) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2885 | - | 1e-32 | 36.59% (246) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 1e-63 | 52.38% (252) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2788c|M.bovis_AF2122/97 -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAH-VV
Rv2766c|M.tuberculosis_H37Rv -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAH-VV
MMAR_0587|M.marinum_M ---------------MGQLEGKTALVTGGNSGIGLAAAQRLAAEGAH-VF
MSMEG_6823|M.smegmatis_MC2_155 ---------------MGQLDGKTALVTGGTSGIGHAAAKRLVQEGAY-VF
MAV_2726|M.avium_104 ---------------MGLLDRKTAVITGANSGIGLATAERFLAEGVERVF
Mvan_1616|M.vanbaalenii_PYR-1 ---------------MGTLEGKTAVVTGASSGIGLAAAQRLADEGAH-VF
TH_2488|M.thermoresistible__bu ----------------MEFQGLHVLVTGGTGGIGLACARAFAEAGAE-VT
MUL_2885|M.ulcerans_Agy99 -------------MRYPDLAGKATIVTGAGAGIGLAIAERLAAEGAA-VL
Mflv_1235|M.gilvum_PYR-GCK --------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAGIN-VV
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGAN-VA
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR-VA
: :**. *** . * : * *
Mb2788c|M.bovis_AF2122/97 LTAR----RQEAADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGS
Rv2766c|M.tuberculosis_H37Rv LTAR----RQEAADEAAAQVGDRALGVGAHAVDEDAARRCVDLTLERFGS
MMAR_0587|M.marinum_M LTGR----NQATIDAAVASIGSRAHGIRADVSNIEDLARVADAIAAAGRG
MSMEG_6823|M.smegmatis_MC2_155 ITGR----DRTRAEKAAASIG--AHGVQSDVSNPDELDALAAEIAEYGKG
MAV_2726|M.avium_104 ITGR----RQRELEDAARQLGPRATAVRGDVGAPRDLDRLYGEVAAAGAG
Mvan_1616|M.vanbaalenii_PYR-1 ITGR----KKPALDAAAASLGSAATAVVGDIARAADLDQLYDAVRARGRG
TH_2488|M.thermoresistible__bu VTGR----DAG-RGAAAAGAHPRLRFIRGDLA---DLASVQNLIRYAD-A
MUL_2885|M.ulcerans_Agy99 CADI----DGASAEQAAAKIGSGAVGYQVDVSAEEQVAGMVEACVTSFGG
Mflv_1235|M.gilvum_PYR-GCK ITARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAIERHGG
MAB_0952|M.abscessus_ATCC_1997 VAARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGA
MLBr_01807|M.leprae_Br4923 VTHR------------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGP
: .
Mb2788c|M.bovis_AF2122/97 VDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
Rv2766c|M.tuberculosis_H37Rv VDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
MMAR_0587|M.marinum_M LDVLFANAGG-GEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLP-LLNS
MSMEG_6823|M.smegmatis_MC2_155 LDVVFANAGG-GDYATLAEVTPQHYRDNIDRNVGGTVFTVQKILP-LLND
MAV_2726|M.avium_104 LDIVMANAGT-TRVARLGEITDDDLDTLLGTNVKGVVYTVQKALP-LLND
Mvan_1616|M.vanbaalenii_PYR-1 LDVLFANAGL-AVLGPLAQATEADYEQNFDVNVRGTWLTVQKAAP-LLND
TH_2488|M.thermoresistible__bu VDVLVNNAAS-FPGALTVEQDAESFTRTFATNVTGTYFLTAGLIPGMLAR
MUL_2885|M.ulcerans_Agy99 LDKLVANAGV-VHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVER
Mflv_1235|M.gilvum_PYR-GCK LDIVCPNAGI-FPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDALTAS
MAB_0952|M.abscessus_ATCC_1997 LDVVCANAGI-FPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTAS
MLBr_01807|M.leprae_Br4923 VEVLVANAGI-TSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
:: : **. : *. . .
Mb2788c|M.bovis_AF2122/97 HGGAVVNTASIGG-MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
Rv2766c|M.tuberculosis_H37Rv HGGAVVNTASIGG-MHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVN
MMAR_0587|M.marinum_M G-ASIVLTGSTAA-YNGSPAFSVYAATKAAIRSFGRTWAAELVSRNIRVN
MSMEG_6823|M.smegmatis_MC2_155 G-ASIILTGSTAP-AKGTPAFGLYAASKAAIRSLGRTWAAELVDRNIRVN
MAV_2726|M.avium_104 G-ASIILTGSTTA-DRGRAGLSIYAATKAAVRSLARAWANELAHRNIRVN
Mvan_1616|M.vanbaalenii_PYR-1 G-ASVIVNSSIRA-DDGWENFGLYSASKAAVRSLARTWANELKDRGIRVN
TH_2488|M.thermoresistible__bu GRGSIVNITSMVA-TKAVPGASVYSSSKAAVESLTRSWAVEFAAHGIRVN
MUL_2885|M.ulcerans_Agy99 GGGAIVNMSSLAG-HIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSN
Mflv_1235|M.gilvum_PYR-GCK GHGRVIITSSITGPITGFPGWSHYGASKAAQLGFLRTAAIELAPKKITVN
MAB_0952|M.abscessus_ATCC_1997 GRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVN
MLBr_01807|M.leprae_Br4923 RFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRSITAN
. : * . * :*:. . : * *: : *
Mb2788c|M.bovis_AF2122/97 AICPGVVRTRLAEALWKDH---------EDPLAATIALGRIGEPADIASA
Rv2766c|M.tuberculosis_H37Rv AICPGVVRTRLAEALWKDH---------EDPLAATIALGRIGEPADIASA
MMAR_0587|M.marinum_M TVVPGPVETPGLKGLAPEG----QEQQLLEGEAAKVPMGRLGKPAEIAAA
MSMEG_6823|M.smegmatis_MC2_155 TVIPGPIRTPGLEGLAPDG----QRE--LDGWAAQVPMKRLGDPDEIATA
MAV_2726|M.avium_104 VLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHA
Mvan_1616|M.vanbaalenii_PYR-1 TVSPGAIDTPAVDKVVDPE----VASAFKAELVKGVPIGRLGRPEEVAAA
TH_2488|M.thermoresistible__bu AVAPGPTSTDGVATEWGET---------NEALGRALPIGRTADPDEIAQA
MUL_2885|M.ulcerans_Agy99 ALLPAFVDTPMQQSAMAMFD--EVLGTGGANTMIARLQGRMARPEEMARI
Mflv_1235|M.gilvum_PYR-GCK AVLPGNILTEGLVEMGQSY---------IDQMAAAVPAGKLGEVADIGNA
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVDMGEEY---------ISGMARSIPMGMLGSPVDIGHL
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKY---------QEAALQAIPLGRIGAVEEIAGA
.: .. * . ::.
Mb2788c|M.bovis_AF2122/97 VAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv VAFLVSDAASWITGETMIIDGGLLLGNALGFRAAPSTEH
MMAR_0587|M.marinum_M VLFLASDQSSFMTGSEMFVDGGTEQL-------------
MSMEG_6823|M.smegmatis_MC2_155 VLFLASNQSSFMTGAELVVDGGQIQI-------------
MAV_2726|M.avium_104 AVFLASDLSSFCTGSTVTADGGFNQV-------------
Mvan_1616|M.vanbaalenii_PYR-1 VAFLASADSSFIYGANLDIDGGEHQV-------------
TH_2488|M.thermoresistible__bu VVFLASSRASFITGAVLHVDGGGIAV-------------
MUL_2885|M.ulcerans_Agy99 VAFLLPDDSSMITGTTQIADGGTIAALW-----------
Mflv_1235|M.gilvum_PYR-GCK ALFFATDEAAYITGQSLVVDGGQILPESPEALADL----
MAB_0952|M.abscessus_ATCC_1997 AAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP-----
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH------------
. *: . :. * ***