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ARPTQRSPDGARADPEDRTARFMRSALAILGETGRTDFTVLEVVERSKTSLRSFYQHFSSKDELLLALID RIMAESAQRWRADTEALPGPEALRVLVEKITAPASSSTQDSINRGLTYYNDHLAESLPREYARVLAPLHD LIRGIVRRGIDAGDFHSGVEVDTTSALILQSVLGAMRLRSLGVELNGTPIEGPHIYEFCVRSLSNPPTPD DQAFPRRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2995 | - | - | 100% (219) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4847 | - | 5e-21 | 33.65% (208) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1611 | - | 2e-05 | 24.48% (192) | transcriptional regulator, TetR family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-05 | 28.26% (184) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_3791 | - | 8e-76 | 65.85% (205) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 1e-05 | 28.26% (184) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | MLBr_01070 | - | 8e-06 | 30.00% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1576 | - | 3e-06 | 24.87% (197) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3987 | - | 4e-62 | 58.33% (204) | putative transcriptional regulatory protein |
| M. avium 104 | MAV_1626 | - | 4e-63 | 58.08% (198) | hypothetical protein MAV_1626 |
| M. thermoresistible (build 8) | TH_0537 | - | 1e-68 | 63.26% (215) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3848 | - | 7e-62 | 56.07% (214) | putative transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2603 | - | 2e-73 | 62.80% (207) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3860c|M.bovis_AF2122/97 -MVRPPQ-----------TARSER----TREALRQAALVRFLAQGVEATS
Rv3830c|M.tuberculosis_H37Rv -MVRPPQ-----------TARSER----TREALRQAALVRFLAQGVEATS
Mflv_3791|M.gilvum_PYR-GCK -MSAKAQPD---PTVRQDPAVRQDRAQSRAGRFMRSALDILGETGRTDFT
Mvan_2603|M.vanbaalenii_PYR-1 -MSAKAQPS---PTAQRDGAQQE----SRASRFMRSALDILGETGRTDFT
MSMEG_2995|M.smegmatis_MC2_155 -MARPTQRS---PDGAR--ADPE----DRTARFMRSALAILGETGRTDFT
TH_0537|M.thermoresistible__bu -MANPTS------------ADTE----SRADRFLRSALTILGETGRTDFT
MMAR_3987|M.marinum_M -MAGPSE-------------QVEA---TRADRFIKTAVEILGETGRTDFT
MUL_3848|M.ulcerans_Agy99 -MAGPSE-------------QVEA---TRADRFIKTAVEILGETGRTDFT
MAV_1626|M.avium_104 -MAEPNE-------------DVEI---TRGDRFIKTAVAILGETGRTDFT
MAB_1576|M.abscessus_ATCC_1997 -MTRPGAPLGKLMARAVRGLGSHPEPDDIETRLLDAAIEVLSERGTQTAT
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
: . : * : :
Mb3860c|M.bovis_AF2122/97 AEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESI
Rv3830c|M.tuberculosis_H37Rv AEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESI
Mflv_3791|M.gilvum_PYR-GCK VLEVVERSKTSLRAFYQHFSTKDELLLALVEKIMAEATERWRAETEQLAG
Mvan_2603|M.vanbaalenii_PYR-1 VLEVVERSKTSLRAFYQHFATKDELLLALVERVMVDATERWRAETDRMTS
MSMEG_2995|M.smegmatis_MC2_155 VLEVVERSKTSLRSFYQHFSSKDELLLALIDRIMAESAQRWRADTEALPG
TH_0537|M.thermoresistible__bu VLEVVERSKTSLRSFYQHFSTKDELLLALIDTIMAESAARWRAELEGLPA
MMAR_3987|M.marinum_M VQEVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGLDS
MUL_3848|M.ulcerans_Agy99 VQEVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGLDS
MAV_1626|M.avium_104 VQEVVARSKTSLRAFYQHFSSKDELLLALFDRTIAQSAQTWRAETAGLDS
MAB_1576|M.abscessus_ATCC_1997 IDEVARRAKVGRATVFRRFSSKDQLFERALAQEMRKFLDELQARAGEFDD
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
::. : . :.: * :*. :: *
Mb3860c|M.bovis_AF2122/97 IDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQ
Rv3830c|M.tuberculosis_H37Rv IDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQ
Mflv_3791|M.gilvum_PYR-GCK PDALRVLIDRISAPAQSSTQDSINRGLTYYNDHLLETRPKEFATVLAPLH
Mvan_2603|M.vanbaalenii_PYR-1 DDALRLLIERISAPAESSTQDSINRGLTYYNDHLLETRPKEFAKVLAPLH
MSMEG_2995|M.smegmatis_MC2_155 PEALRVLVEKITAPASSSTQDSINRGLTYYNDHLAESLPREYARVLAPLH
TH_0537|M.thermoresistible__bu AQALRTLIERICTPAGSSRQDYINRGLTSYNDRLADTLPREYARVLAPLH
MMAR_3987|M.marinum_M TAALKLVIDRISAQPESSTQDSLNRALSLYNQHLAETRPREYARVLSPLH
MUL_3848|M.ulcerans_Agy99 TAALKLVIDRISAQPESSTQDSLNRALSLYNQHLAETRPREYARVLSPLH
MAV_1626|M.avium_104 TAALKLVIDRVSQQPESSTQDSLNRALTLYNQHLAETRPREYARVLSPLH
MAB_1576|M.abscessus_ATCC_1997 IG--ERVAEGFAVCIEIVNHPLLRGDSLVARMTAVEAITQGDPAPIELAR
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVR-RLWSTVMQQWI
: . .
Mb3860c|M.bovis_AF2122/97 AQLRRRNCDIAGAPDAR------------LHIAVTARCVAAAVFGAMEAW
Rv3830c|M.tuberculosis_H37Rv AQLRRRNCDIAGAPDAR------------LHIAVTARCVAAAVFGAMEAW
Mflv_3791|M.gilvum_PYR-GCK RLLGDILRRGIAEGSFR----------ADLDVDTDAAILMQTVLGTLRLR
Mvan_2603|M.vanbaalenii_PYR-1 RLVADILRRGIDEGTFR----------ADLDVDTDAAILMHTVLGVLRLR
MSMEG_2995|M.smegmatis_MC2_155 DLIRGIVRRGIDAGDFH----------SGVEVDTTSALILQSVLGAMRLR
TH_0537|M.thermoresistible__bu QLIVDILRRGVAEGAFRGPGETAPDGGVDADLDAVAALIMQTALGAMRLR
MMAR_3987|M.marinum_M RLIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGALRLR
MUL_3848|M.ulcerans_Agy99 RLIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGALRLR
MAV_1626|M.avium_104 RLIRDIVGQGITEGVFN----------PGLDVGAAAAIVMQTMMGAQRLH
MAB_1576|M.abscessus_ATCC_1997 NYLAAQIDQMREEGRIP-----------PGDSRRQVDVLIHLVLGYLAAP
MLBr_01070|M.leprae_Br4923 DYNTAAIQAERKCGVAP-----------DTIPAEDLAVALQLMTERVMAA
Mb3860c|M.bovis_AF2122/97 MLGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS-------------
Rv3830c|M.tuberculosis_H37Rv MLGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS-------------
Mflv_3791|M.gilvum_PYR-GCK ELGADLNGIPIEGSHVHTFCLRGLTPP-----------------------
Mvan_2603|M.vanbaalenii_PYR-1 DLGAELNGVPIVGDHVHTFCVRGLTG------------------------
MSMEG_2995|M.smegmatis_MC2_155 SLGVELNGTPIEGPHIYEFCVRSLSNPPTPDDQAFPRRP-----------
TH_0537|M.thermoresistible__bu ALGAELGGAPIDAELIYTFCLHGLARTTDS--------------------
MMAR_3987|M.marinum_M WLGTELNATPIDAGELYEFCSRALGVRDAEESA-ASSLTELFAQIGMRQE
MUL_3848|M.ulcerans_Agy99 WLGTELNAMPIDAGELYEFCSRALGVRDTEESA-ASSLTELFAQIGMRQE
MAV_1626|M.avium_104 WLGAELNGTPVDAGQLYDFCSRALGIRDTDEDAGAPSLAELFGQIGMRPG
MAB_1576|M.abscessus_ATCC_1997 ATTIDLGNTEEVRALARETFAPILLTPNVPLKAP----------------
MLBr_01070|M.leprae_Br4923 TFSDEKPLIPDKKVIDTLVHIWLASIYGS---------------------
:
Mb3860c|M.bovis_AF2122/97 --------------------------------------------------
Rv3830c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3791|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155 --------------------------------------------------
TH_0537|M.thermoresistible__bu --------------------------------------------------
MMAR_3987|M.marinum_M PSHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYLPPGAA
MUL_3848|M.ulcerans_Agy99 PSHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYLPPGAA
MAV_1626|M.avium_104 -TRNGQFAMTMPVSPAVVNTSGALQGGLIATLVDVAGGQFGLDYLRPGTT
MAB_1576|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
Mb3860c|M.bovis_AF2122/97 --------------------------------------------------
Rv3830c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_3791|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155 --------------------------------------------------
TH_0537|M.thermoresistible__bu --------------------------------------------------
MMAR_3987|M.marinum_M MTTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSADELAAT
MUL_3848|M.ulcerans_Agy99 MTTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSADELAAT
MAV_1626|M.avium_104 MTTADLFVRYLRPVRQGSAFAVPRMLRSGRRAMVMQVDIFGDGDDELLAT
MAB_1576|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
Mb3860c|M.bovis_AF2122/97 ----------------------
Rv3830c|M.tuberculosis_H37Rv ----------------------
Mflv_3791|M.gilvum_PYR-GCK ----------------------
Mvan_2603|M.vanbaalenii_PYR-1 ----------------------
MSMEG_2995|M.smegmatis_MC2_155 ----------------------
TH_0537|M.thermoresistible__bu ----------------------
MMAR_3987|M.marinum_M ATVNFAIIDRNDTTETG-----
MUL_3848|M.ulcerans_Agy99 ATVNFAIIDRNDTTETG-----
MAV_1626|M.avium_104 ATVNFAIIN-GDTPSSGLPPAE
MAB_1576|M.abscessus_ATCC_1997 ----------------------
MLBr_01070|M.leprae_Br4923 ----------------------