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MAGPSEQVEATRADRFIKTAVEILGETGRTDFTVQEVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQT AQLWRAEAAGLDSTAALKLVIDRISAQPESSTQDSLNRALSLYNQHLAETRPREYARVLSPLHRLIRDIV GQGITEGMFNPGLDVGAAAAIVMQTVLGALRLRWLGTELNATPIDAGELYEFCSRALGVRDAEESAASSL TELFAQIGMRQEPSHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYLPPGAAMTTADLFI RYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSADELAATATVNFAIIDRNDTTETG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3987 | - | - | 100% (339) | putative transcriptional regulatory protein |
| M. marinum M | MMAR_4752 | - | 2e-20 | 33.86% (189) | transcriptional regulatory protein |
| M. marinum M | MMAR_3144 | - | 1e-06 | 28.14% (199) | AcrR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 8e-05 | 23.90% (205) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_3791 | - | 4e-61 | 61.50% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3830c | - | 8e-05 | 23.90% (205) | transcriptional regulatory protein TetR-family |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2494c | - | 2e-07 | 28.22% (163) | putative transcriptional regulator |
| M. avium 104 | MAV_1626 | - | 1e-152 | 81.82% (341) | hypothetical protein MAV_1626 |
| M. smegmatis MC2 155 | MSMEG_2995 | - | 8e-62 | 58.33% (204) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0537 | - | 5e-58 | 56.52% (207) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3848 | - | 0.0 | 99.41% (339) | putative transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2603 | - | 8e-61 | 61.38% (189) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3987|M.marinum_M -----MAGPSE------QVEA---TRADRFIKTAVEILGET-GRTDFTVQ
MUL_3848|M.ulcerans_Agy99 -----MAGPSE------QVEA---TRADRFIKTAVEILGET-GRTDFTVQ
MAV_1626|M.avium_104 -----MAEPNE------DVEI---TRGDRFIKTAVAILGET-GRTDFTVQ
Mflv_3791|M.gilvum_PYR-GCK MSAKAQPDPTVRQD-PAVRQDRAQSRAGRFMRSALDILGET-GRTDFTVL
Mvan_2603|M.vanbaalenii_PYR-1 MSAKAQPSPTAQRD-GAQQE----SRASRFMRSALDILGET-GRTDFTVL
TH_0537|M.thermoresistible__bu -----MANPTS-----ADTE----SRADRFLRSALTILGET-GRTDFTVL
MSMEG_2995|M.smegmatis_MC2_155 MARPTQRSPDGAR---ADPE----DRTARFMRSALAILGET-GRTDFTVL
Mb3860c|M.bovis_AF2122/97 -----MVRPPQ----TARSER----TREALRQAALVRFLAQ-GVEATSAE
Rv3830c|M.tuberculosis_H37Rv -----MVRPPQ----TARSER----TREALRQAALVRFLAQ-GVEATSAE
MAB_2494c|M.abscessus_ATCC_199 -----MSSPAGRSYSGLPADERLARRRQRLLEVGLDILGTPDGSGDLTLR
* : : . .: : * :
MMAR_3987|M.marinum_M EVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGLDSTA
MUL_3848|M.ulcerans_Agy99 EVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGLDSTA
MAV_1626|M.avium_104 EVVARSKTSLRAFYQHFSSKDELLLALFDRTIAQSAQTWRAETAGLDSTA
Mflv_3791|M.gilvum_PYR-GCK EVVERSKTSLRAFYQHFSTKDELLLALVEKIMAEATERWRAETEQLAGPD
Mvan_2603|M.vanbaalenii_PYR-1 EVVERSKTSLRAFYQHFATKDELLLALVERVMVDATERWRAETDRMTSDD
TH_0537|M.thermoresistible__bu EVVERSKTSLRSFYQHFSTKDELLLALIDTIMAESAARWRAELEGLPAAQ
MSMEG_2995|M.smegmatis_MC2_155 EVVERSKTSLRSFYQHFSSKDELLLALIDRIMAESAQRWRADTEALPGPE
Mb3860c|M.bovis_AF2122/97 QIAEDAGVSLRTFYRHFRSKHDLLFADYD----AGLHWFRAALDARPADE
Rv3830c|M.tuberculosis_H37Rv QIAEDAGVSLRTFYRHFRSKHDLLFADYD----AGLHWFRAALDARPADE
MAB_2494c|M.abscessus_ATCC_199 TVCQRSGLAQRYFYESFADKDEYAAAIFDWAIEGLAATVEAEVAAAHPRL
: : : * **. * *.: * : .*
MMAR_3987|M.marinum_M ALKLVIDRISAQPESSTQD-SLNRALSLYNQHLAETRPREYARVLSPLHR
MUL_3848|M.ulcerans_Agy99 ALKLVIDRISAQPESSTQD-SLNRALSLYNQHLAETRPREYARVLSPLHR
MAV_1626|M.avium_104 ALKLVIDRVSQQPESSTQD-SLNRALTLYNQHLAETRPREYARVLSPLHR
Mflv_3791|M.gilvum_PYR-GCK ALRVLIDRISAPAQSSTQD-SINRGLTYYNDHLLETRPKEFATVLAPLHR
Mvan_2603|M.vanbaalenii_PYR-1 ALRLLIERISAPAESSTQD-SINRGLTYYNDHLLETRPKEFAKVLAPLHR
TH_0537|M.thermoresistible__bu ALRTLIERICTPAGSSRQD-YINRGLTSYNDRLADTLPREYARVLAPLHQ
MSMEG_2995|M.smegmatis_MC2_155 ALRVLVEKITAPASSSTQD-SINRGLTYYNDHLAESLPREYARVLAPLHD
Mb3860c|M.bovis_AF2122/97 SIIDSVQAAIFSFPYDVDA-VTKIASLRRGELEPSRIVRHMREVEADFAD
Rv3830c|M.tuberculosis_H37Rv SIIDSVQAAIFSFPYDVDA-VTKIASLRRGELEPSRIVRHMREVEADFAD
MAB_2494c|M.abscessus_ATCC_199 QVRAGITSVVRAVSADRRIGQLLYSRHQVNPVLVRRRFDATAMFVSLFAQ
: : . . . . : :
MMAR_3987|M.marinum_M LIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGALRLRW
MUL_3848|M.ulcerans_Agy99 LIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGALRLRW
MAV_1626|M.avium_104 LIRDIVGQGITEGVFN----------PGLDVGAAAAIVMQTMMGAQRLHW
Mflv_3791|M.gilvum_PYR-GCK LLGDILRRGIAEGSFR----------ADLDVDTDAAILMQTVLGTLRLRE
Mvan_2603|M.vanbaalenii_PYR-1 LVADILRRGIDEGTFR----------ADLDVDTDAAILMHTVLGVLRLRD
TH_0537|M.thermoresistible__bu LIVDILRRGVAEGAFRGPGETAPDGGVDADLDAVAALIMQTALGAMRLRA
MSMEG_2995|M.smegmatis_MC2_155 LIRGIVRRGIDAGDFH----------SGVEVDTTSALILQSVLGAMRLRS
Mb3860c|M.bovis_AF2122/97 AIQAQLRRRNCDIAGAP--------DARLHIAVTARCVAAAVFGAMEAWM
Rv3830c|M.tuberculosis_H37Rv AIQAQLRRRNCDIAGAP--------DARLHIAVTARCVAAAVFGAMEAWM
MAB_2494c|M.abscessus_ATCC_199 HLHDWFRR---------------------DDQGNLPVLAHFIVGGVGQAV
: . : . : .*
MMAR_3987|M.marinum_M LGTELNATPIDAGELYEFCSRALGVRDAEESA-ASSLTELFAQIGMRQEP
MUL_3848|M.ulcerans_Agy99 LGTELNAMPIDAGELYEFCSRALGVRDTEESA-ASSLTELFAQIGMRQEP
MAV_1626|M.avium_104 LGAELNGTPVDAGQLYDFCSRALGIRDTDEDAGAPSLAELFGQIGMRPG-
Mflv_3791|M.gilvum_PYR-GCK LGADLNGIPIEGSHVHTFCLRGLTPP------------------------
Mvan_2603|M.vanbaalenii_PYR-1 LGAELNGVPIVGDHVHTFCVRGLTG-------------------------
TH_0537|M.thermoresistible__bu LGAELGGAPIDAELIYTFCLHGLARTTDS---------------------
MSMEG_2995|M.smegmatis_MC2_155 LGVELNGTPIEGPHIYEFCVRSLSNPPTPDDQAFPRRP------------
Mb3860c|M.bovis_AF2122/97 LGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS--------------
Rv3830c|M.tuberculosis_H37Rv LGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS--------------
MAB_2494c|M.abscessus_ATCC_199 TAWLHQEVTISEDELIEQLVDMLLAHGPAGSGQR----------------
. : :
MMAR_3987|M.marinum_M SHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYLPPGAAM
MUL_3848|M.ulcerans_Agy99 SHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYLPPGAAM
MAV_1626|M.avium_104 TRNGQFAMTMPVSPAVVNTSGALQGGLIATLVDVAGGQFGLDYLRPGTTM
Mflv_3791|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0537|M.thermoresistible__bu --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155 --------------------------------------------------
Mb3860c|M.bovis_AF2122/97 --------------------------------------------------
Rv3830c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2494c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3987|M.marinum_M TTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSADELAATA
MUL_3848|M.ulcerans_Agy99 TTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSADELAATA
MAV_1626|M.avium_104 TTADLFVRYLRPVRQGSAFAVPRMLRSGRRAMVMQVDIFGDGDDELLATA
Mflv_3791|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0537|M.thermoresistible__bu --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155 --------------------------------------------------
Mb3860c|M.bovis_AF2122/97 --------------------------------------------------
Rv3830c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_2494c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3987|M.marinum_M TVNFAIIDRNDTTETG-----
MUL_3848|M.ulcerans_Agy99 TVNFAIIDRNDTTETG-----
MAV_1626|M.avium_104 TVNFAIIN-GDTPSSGLPPAE
Mflv_3791|M.gilvum_PYR-GCK ---------------------
Mvan_2603|M.vanbaalenii_PYR-1 ---------------------
TH_0537|M.thermoresistible__bu ---------------------
MSMEG_2995|M.smegmatis_MC2_155 ---------------------
Mb3860c|M.bovis_AF2122/97 ---------------------
Rv3830c|M.tuberculosis_H37Rv ---------------------
MAB_2494c|M.abscessus_ATCC_199 ---------------------