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VRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWF RAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRN CDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3830c | - | - | 100% (209) | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| M. tuberculosis H37Rv | Rv3173c | - | 8e-06 | 36.14% (83) | TetR/ACRR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1963c | mce3R | 3e-05 | 28.16% (103) | transcriptional repressor (probably TETR-family) MCE3R |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3860c | - | 1e-116 | 100.00% (209) | transcriptional regulatory protein TetR-family |
| M. gilvum PYR-GCK | Mflv_1676 | - | 1e-72 | 70.00% (200) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3837 | - | 3e-09 | 23.96% (192) | transcriptional regulatory protein TetR |
| M. marinum M | MMAR_5384 | - | 5e-89 | 79.13% (206) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0197 | - | 8e-90 | 81.25% (208) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1420 | - | 4e-08 | 23.94% (188) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_3524 | - | 1e-11 | 32.12% (193) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_5004 | - | 1e-87 | 78.16% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5077 | - | 2e-72 | 69.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1676|M.gilvum_PYR-GCK -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETTAEQIAADAGVSLRT
Mvan_5077|M.vanbaalenii_PYR-1 -MVRPAQTARS-ERTREALRQAAVVRFLAQGVEDTSAEQIAADAGVSLRT
Rv3830c|M.tuberculosis_H37Rv -MVRPPQTARS-ERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
Mb3860c|M.bovis_AF2122/97 -MVRPPQTARS-ERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRT
MAV_0197|M.avium_104 -MVRPAQTARS-ERTREALRQAALVRFLAQGVEDTSAEQIAADAGVSLRT
MMAR_5384|M.marinum_M -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
MUL_5004|M.ulcerans_Agy99 -MVRPAQTVRS-ERTREALRQAAVVRFLAQGVEETSAEQIAADAGVSLRT
MAB_3837|M.abscessus_ATCC_1997 MNAQPARVGRRPSTTRDEITAVAMTLFAQHGFDEVSVDDIAAAAGIARRT
MSMEG_1420|M.smegmatis_MC2_155 -MSEGSRAGRRRSTTQDHIAGVAIDLFAARGFDAVSVDDVAAAAGISRRT
TH_3524|M.thermoresistible__bu --------VRG-HRNREALIAAAIDLFTVNGYEQTTVEQIAEAAGVAPRT
* .:: : .*: * .* : .:.:::* **:: **
Mflv_1676|M.gilvum_PYR-GCK FYRHFASKHDLLFADYDAGLHWFRAALATRSPEDPILDTVQAAIMAAP-Y
Mvan_5077|M.vanbaalenii_PYR-1 FYRHFASKHDLLFADYDAGLHWFRSALAARSPEESIFESVQSAIMASP-Y
Rv3830c|M.tuberculosis_H37Rv FYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP-Y
Mb3860c|M.bovis_AF2122/97 FYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFP-Y
MAV_0197|M.avium_104 FYRHFRSKHDLLFADY-TGLHWFRAALDARPADEPIIDSVQAAIFSFP-Y
MMAR_5384|M.marinum_M FYRHFRSKHDLLFADY-TGLHWFRAALDARPVDETIIDSVQTAIFAFP-Y
MUL_5004|M.ulcerans_Agy99 FYRHFRSKHDLLFADY-TGLHWFRAALDARPVDEAIIDSVQTAIFAFP-Y
MAB_3837|M.abscessus_ATCC_1997 VFRYYSSKNAIVWGDFDSHLGVMRALLDETADTVDTSTALRQAVLTFNDF
MSMEG_1420|M.smegmatis_MC2_155 LFRYYASKSAIPWGDFDSHLQHLQNLLRTLSSEVSLGDALREALLTFNTY
TH_3524|M.thermoresistible__bu FFRHFAAKEDILFHGYADRLAEATRRFRAARSG-SLWKALAEASEAVATA
.:*:: :* : : .: * : :: * :
Mflv_1676|M.gilvum_PYR-GCK DDWAVTKIAAMRSQELDAGRIVRHIRQVEADFADAIDEHLARADGASPGT
Mvan_5077|M.vanbaalenii_PYR-1 EDWAVTKIAAMRAKELDTGRIVRHIRQVEADFAEAVEQHMAAAGAAAPGT
Rv3830c|M.tuberculosis_H37Rv DVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAGA
Mb3860c|M.bovis_AF2122/97 DVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAGA
MAV_0197|M.avium_104 DVDAVTKIAALRHEELDPGRIVRHIRDVQADFAEAIAAQLQRRGRG-AGA
MMAR_5384|M.marinum_M DVEAVAKIATLRGGELDPSRIVRHIQEVQADFAEVIAAQLRRRSCAAAGT
MUL_5004|M.ulcerans_Agy99 DVEAVAKIATLRGGELDPSRIVRHIQEVQADFAEVIAAQLLRRSCAAAGT
MAB_3837|M.abscessus_ATCC_1997 PVDETPRHRMRMRMILEVPALQAYSMLMYTGWRDVIAQFVARRSGTDP--
MSMEG_1420|M.smegmatis_MC2_155 ADHEMAEHRQRMRVILETEELQAYSMTMYAGWRTVIAEYVADRLGMST--
TH_3524|M.thermoresistible__bu IAENPGIFLVRARMYGELPALRATMLRINDDWIDQMTTEVARWLGSDAAV
: : : .: : : .
Mflv_1676|M.gilvum_PYR-GCK D-----ERMRTTVTARCIAAAVFGAMEVWMLGEDSSLPELDRLCRHALDL
Mvan_5077|M.vanbaalenii_PYR-1 D-----ERMRTTVTARCIAAAVFGAMEVWMLGEDRSLPELDRLCRQALTL
Rv3830c|M.tuberculosis_H37Rv P----DARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALES
Mb3860c|M.bovis_AF2122/97 P----DARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALES
MAV_0197|M.avium_104 PTA--DQRVRAAVTARCIAAAVFGAMEVWMVGDERSLGELARLCHAALES
MMAR_5384|M.marinum_M SAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRSLGELARVCQLALET
MUL_5004|M.ulcerans_Agy99 SAQTPDARVRTAVTARCIAAAVFGAMEVWMLGEDRSLGELARVCQLALET
MAB_3837|M.abscessus_ATCC_1997 ------GSLLPQTVAWTLLGVALAAYEQWLADESS---KLTTLLGKGFDA
MSMEG_1420|M.smegmatis_MC2_155 ------TDLMPQTVAWLMLGVALSAYENWLADESV---SLRGAIAAAFEV
TH_3524|M.thermoresistible__bu D-------VRPRLAATVINGANRTAIDLWVSADGK--GDLVELMADAVRL
: .* : .. * : *: . .* ..
Mflv_1676|M.gilvum_PYR-GCK LRTGIADPA----------------
Mvan_5077|M.vanbaalenii_PYR-1 LRSGIEDPVG---------------
Rv3830c|M.tuberculosis_H37Rv LRVGISDTWTTLT---VSS------
Mb3860c|M.bovis_AF2122/97 LRVGISDTWTTLT---VSS------
MAV_0197|M.avium_104 LRAGITDSWSTATAPQVSS------
MMAR_5384|M.marinum_M LRAGLTNTWCPDRPRTVSS------
MUL_5004|M.ulcerans_Agy99 SRAGLTNTWCPDRPRTVSS------
MAB_3837|M.abscessus_ATCC_1997 AEVGLRALR----------------
MSMEG_1420|M.smegmatis_MC2_155 ARPGLDALQPAH-------------
TH_3524|M.thermoresistible__bu VRPTLDRIERESRTVANPVRRRDVV
. :