For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTRPGAPLGKLMARAVRGLGSHPEPDDIETRLLDAAIEVLSERGTQTATIDEVARRAKVGRATVFRRFSS KDQLFERALAQEMRKFLDELQARAGEFDDIGERVAEGFAVCIEIVNHPLLRGDSLVARMTAVEAITQGDP APIELARNYLAAQIDQMREEGRIPPGDSRRQVDVLIHLVLGYLAAPATTIDLGNTEEVRALARETFAPIL LTPNVPLKAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1576 | - | - | 100% (220) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1024 | - | 4e-17 | 27.81% (187) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4647 | - | 2e-11 | 27.72% (202) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 6e-07 | 37.29% (59) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0059 | - | 1e-14 | 30.61% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 6e-07 | 37.29% (59) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 4e-06 | 29.69% (64) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0287 | - | 3e-13 | 26.09% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_5227 | - | 8e-14 | 28.72% (188) | TetR-family protein transcriptional regulator, putative |
| M. smegmatis MC2 155 | MSMEG_0962 | - | 7e-10 | 26.13% (199) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4364 | - | 4e-11 | 38.46% (104) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4837 | - | 2e-13 | 26.09% (184) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0855 | - | 1e-12 | 29.38% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0287|M.marinum_M --------MQSRMGTETSTDGVESITDLDRTILDTARAVFETYGVRRANI
MUL_4837|M.ulcerans_Agy99 ------------MGTETSTDGVESITDLDRTILDTAHAVFETYGVRRANI
MAV_5227|M.avium_104 ------------MQSHRADAAAGERTDLDRLILDTARGVFETYGVRRANI
Mflv_0059|M.gilvum_PYR-GCK ---------------------MSGPDPASEQILDAAVVEFERHGFRRVAL
Mvan_0855|M.vanbaalenii_PYR-1 ---------------------MRGTD-ATEHILDAAVVEFERHGFRRVAL
MSMEG_0962|M.smegmatis_MC2_155 ---------------------MPGPDAASRAILDAALVEFERYGFRRVAL
Mb0068c|M.bovis_AF2122/97 -------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPV
Rv0067c|M.tuberculosis_H37Rv -------------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPV
MAB_1576|M.abscessus_ATCC_1997 MTRPGAPLGKLMARAVRGLGSHPEPDDIETRLLDAAIEVLSERGTQTATI
TH_4364|M.thermoresistible__bu -----------MRTHGWRGTPPRSDDEAVERILAATHRCVAERGGQ-TTI
MLBr_02568|M.leprae_Br4923 ---------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSM
:* .: . * . :
MMAR_0287|M.marinum_M EDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR
MUL_4837|M.ulcerans_Agy99 EDVATRAGVSRSTIYRRFPTKDELFERVVRREAELFFAALNQATNGHNPR
MAV_5227|M.avium_104 DDVAARAGVSRSTIYRRFPTKKNLFGQVVRREAELFFSTLDQATAGCDPQ
Mflv_0059|M.gilvum_PYR-GCK EDVARRAGVSRTTIYRRFANKDQLVGAVIERENVALFSDIATELKQAGPQ
Mvan_0855|M.vanbaalenii_PYR-1 DDVARRAGVSRTTIYRRFANKDELVGAVIERENIQLFADIAAELKTAGPQ
MSMEG_0962|M.smegmatis_MC2_155 DDVARRAGVSRTTIYRRFANRDDLVGAVIERENVSLFADIAAELKDAKPQ
Mb0068c|M.bovis_AF2122/97 DEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPG
Rv0067c|M.tuberculosis_H37Rv DEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPG
MAB_1576|M.abscessus_ATCC_1997 DEVARRAKVGRATVFRRFSSKDQLFERALAQEMRKFLDELQARAGEFDDI
TH_4364|M.thermoresistible__bu AHVAAELGVSRATVYRYFPSTSALLQAAAVEGTRRFLHRMAERLGRIDDV
MLBr_02568|M.leprae_Br4923 DAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSP
:* . :. :: : . . *. ::
MMAR_0287|M.marinum_M -EAVIEAFTLGVRLIQDSPLYSRIAESEP-ELFGMFSRSHVFPIGQFADG
MUL_4837|M.ulcerans_Agy99 -EAVIEAFTLGVRLIRDSPLYSRIAESEP-ELFGMFSRSHVFPIGQFADG
MAV_5227|M.avium_104 -QAVIEAFALGVRLVKNSALYSRIAESEP-ELFGLFSRSQVFPIRQFADG
Mflv_0059|M.gilvum_PYR-GCK SNYYVEAFTLSILKFRGHRVLHRMITEEPGLVLELASLYYRAAIERMAEA
Mvan_0855|M.vanbaalenii_PYR-1 SNYYVEAFTLSILKFRRHRVLHQMIIDEPGLVLELAGRYHRAAIDRMAAA
MSMEG_0962|M.smegmatis_MC2_155 SNIYVEAFTLSILRFRRHRVLNQMMKDEPALVLELAHRHYGAAIERMAAA
Mb0068c|M.bovis_AF2122/97 --DALFAFLRSMVLQWG-ATDRGLVEALAGVGIEISS-AAPEAEADFLDL
Rv0067c|M.tuberculosis_H37Rv --DALFAFLRSMVLQWG-ATDRGLVEALAGVGIEISS-AAPEAEADFLDL
MAB_1576|M.abscessus_ATCC_1997 GERVAEGFAVCIEIVNH-PLLRGDSLVARMTAVEAITQGDPAPIELARNY
TH_4364|M.thermoresistible__bu ADAIIEGVVQTVAAVPNEPYLRLLLDEPSHVLLRDVTSESAREIGKSMLL
MLBr_02568|M.leprae_Br4923 -KDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITEL
. .
MMAR_0287|M.marinum_M IAHTLRRCGADAP-DADLANIADILLRV--AVGIIMFPTER-LDTSDDAA
MUL_4837|M.ulcerans_Agy99 IAHTLRRCGADAP-DADLANIADILLRV--AVGIIMFPTER-LDTSDDAA
MAV_5227|M.avium_104 IAHTLRRCGAEQA-EPDLDNIADILLRV--ALGIIVFPTDR-LDTADPAA
Mflv_0059|M.gilvum_PYR-GCK LRVIFPPGFAERIGADAVDELADTILRY--ATMVLLLPSAQPLETADD--
Mvan_0855|M.vanbaalenii_PYR-1 LRVIFPPGFAERIGPAAVDELADCILRY--AAMVLLLPSAQPLETADD--
MSMEG_0962|M.smegmatis_MC2_155 LRVIFPEGFADRIGEAAVNDLADTILRY--ALMALLIPSVEPLETADD--
Mb0068c|M.bovis_AF2122/97 LTDLLRAAQRAGTVRPDVDVLEVKTLLV--GCQAMQSYNAELAAKVTDVA
Rv0067c|M.tuberculosis_H37Rv LTDLLRAAQRAGTVRPDVDVLEVKTLLV--GCQAMQSYNAELAAKVTDVA
MAB_1576|M.abscessus_ATCC_1997 LAAQIDQMREEGRIPPGDSRRQVDVLIH--LVLGYLAAPATTIDLGNTEE
TH_4364|M.thermoresistible__bu ESTSVDWAR-LRPAAEIVDELDELIEWS--LRIVQSFLTDPGDPPRSPDA
MLBr_02568|M.leprae_Br4923 VAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAELM
.
MMAR_0287|M.marinum_M VREYAARYLIPIITL---------------
MUL_4837|M.ulcerans_Agy99 VREYAARYLIPIITL---------------
MAV_5227|M.avium_104 VRDYAARYLVPIIGR---------------
Mflv_0059|M.gilvum_PYR-GCK IRAFARHHFLPSLPEALRSVPA--------
Mvan_0855|M.vanbaalenii_PYR-1 VRAFARQHFLPSLPAALRTVPA--------
MSMEG_0962|M.smegmatis_MC2_155 IRSFATRHFLPSLPVSLRVVPA--------
Mb0068c|M.bovis_AF2122/97 LDGLRANRK---------------------
Rv0067c|M.tuberculosis_H37Rv LDGLRANRK---------------------
MAB_1576|M.abscessus_ATCC_1997 VRALARETFAPILLTPNVPLKAP-------
TH_4364|M.thermoresistible__bu LRAHLHRWLGPAIREWVASVGIDAEQSPPE
MLBr_02568|M.leprae_Br4923 INLFWHGLKGAPADRDFGPSIVAG------
: