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VKYTPGWQPTPVDWASTRGRILLAASQLFAARGYFGTSTRDIADAVSIRQPSLFHHFTAKQEIFRTLVEL DLGPSIDRVRQRLAEESTWAEKLHLTVACDVREILAQPFDARGLYQDAVLAMPEFDEERRGIDLFHDLVE TLIRSGTDAGEFVDFEASFVLRAANGVMFETLREQGGPAGRMRVQRPLQAADFVLRAVMVDPTDLPRIRA VTENRLVKGVLPAGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1611 | - | - | 100% (225) | transcriptional regulator, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_4300 | - | 1e-12 | 35.65% (115) | transcription regulator AmtR |
| M. smegmatis MC2 155 | MSMEG_5718 | - | 3e-09 | 33.94% (109) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3185c | - | 3e-15 | 31.19% (202) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0719 | - | 8e-09 | 25.26% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3160c | - | 3e-15 | 31.19% (202) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-09 | 27.66% (94) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4574c | - | 7e-10 | 27.08% (192) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4832 | - | 2e-09 | 30.60% (134) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 5e-09 | 28.06% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2975 | - | 3e-14 | 36.75% (117) | PUTATIVE putative transcription regulator AmtR |
| M. ulcerans Agy99 | MUL_4731 | - | 1e-08 | 28.00% (175) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 1e-09 | 27.84% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0603|M.avium_104 ----------------------------MTG----PANSRRDELLELAAA
Mvan_5283|M.vanbaalenii_PYR-1 ----------------------------MSSGQAPQANTRRDELLQLAAT
Mflv_0719|M.gilvum_PYR-GCK -------------------------------------MSRREELLAVATK
MUL_4731|M.ulcerans_Agy99 -------------------------------MPSETGLSRREELLAVATK
MAB_4574c|M.abscessus_ATCC_199 --------------------MQPVPEASKAGSSSQRRAGRREELVAVASK
Mb3185c|M.bovis_AF2122/97 -----------------------------MPRQAGRWSPTALRILGAAAE
Rv3160c|M.tuberculosis_H37Rv -----------------------------MPRQAGRWSPTALRILGAAAE
MSMEG_1611|M.smegmatis_MC2_155 -----------------------MKYTPGWQPTPVDWASTRGRILLAASQ
TH_2975|M.thermoresistible__bu -----------VTAGGHPAAAPVTCGRPRSQERRRPGATARDEVLDAAAE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MMAR_4832|M.marinum_M ---------------------------------MRKIPAQISERLPAAAE
. : *:
MAV_0603|M.avium_104 MFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLFA
Mvan_5283|M.vanbaalenii_PYR-1 MFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRGFLDWLFD
Mflv_0719|M.gilvum_PYR-GCK LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
MUL_4731|M.ulcerans_Agy99 LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MAB_4574c|M.abscessus_ATCC_199 LFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIYFKAAEETLA
Mb3185c|M.bovis_AF2122/97 LIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLE
Rv3160c|M.tuberculosis_H37Rv LIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLE
MSMEG_1611|M.smegmatis_MC2_155 LFAARGYFGTSTRDIADAVSIRQPSLFHHFTAKQEIFRTLVELDLGPSID
TH_2975|M.thermoresistible__bu LFTTLGVAATSTRQIAESVGVRQASLYHHFRTKDEILATLLDATVAPSVT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MMAR_4832|M.marinum_M LFAERGLNDTKIEDVAATTGIAKATLYYYFAGKEEILAFLLEDVLQHVAD
::. * : ::* .: . :: :: * : :
MAV_0603|M.avium_104 RYR-EIIDSESNPLERLKGLFMASFEAIEHRHAQVVIYQDEAKRLLSQPR
Mvan_5283|M.vanbaalenii_PYR-1 RYQ-QIVATEPNPLERLKGLFMASFEAIETRHAEVVIYQDEAKRLSAQGR
Mflv_0719|M.gilvum_PYR-GCK ALHDDPTASARETIYHFTRRLLVGIASDIERAAVYFQEGPYISEWFTEEQ
MUL_4731|M.ulcerans_Agy99 ALHAEPSWTAREALYQYTVRLLTGIADNPERAAVYFQEQPYIAEWFTPEQ
MAB_4574c|M.abscessus_ATCC_199 CLQDDPRWSARESLYQCTSRMLALIFSNREQGAVYFQENPFLSEWLSPEQ
Mb3185c|M.bovis_AF2122/97 LFG-HITAMPVPAVVKLHRWLTESLD--HLHASPYVLVSILITPDLHQES
Rv3160c|M.tuberculosis_H37Rv LFG-HITAMPVPAVVKLHRWLTESLD--HLHASPYVLVSILITPDLHQES
MSMEG_1611|M.smegmatis_MC2_155 RVR---QRLAEESTWAEKLHLTVACDVREILAQPFDARGLYQDAVLAMPE
TH_2975|M.thermoresistible__bu AAR---RLRGRPEPPAVLLHALVWLDARLLWDSPHNLGILYLLPEVRDRR
MLBr_00815|M.leprae_Br4923 SVQ-QALRTTTNNRQRLHAAVQAFFDFIEHDGQGYR--LIFENDNITEPR
MMAR_4832|M.marinum_M EVT-AIVEADGTAAQRLHTVINAQLRVMAQRPAVCRALIGELGRAARMPA
MAV_0603|M.avium_104 FSYIEDMNRQQRKMWLEVLNQGVDEGYFRPDL-DVDLVYRFIRDTTWVSV
Mvan_5283|M.vanbaalenii_PYR-1 FAYVEERNKEQRKMWVDVLTQGIDEGYFRPDV-DVDLVYRFIRDTTWVSV
Mflv_0719|M.gilvum_PYR-GCK VDYIREKEAQVYEHVRDVIDRGIASGEFNDCD-SHVLALGYIG-MTLGSY
MUL_4731|M.ulcerans_Agy99 VAEVREKEAQVHEHVHGLIDRGIASGEFYECD-SHVVALGYIG-MTLGSY
MAB_4574c|M.abscessus_ATCC_199 VAEIRTREDMVQERVQNIIERGIASGEFVECD-SHVMALGYIG-MVLGSY
Mb3185c|M.bovis_AF2122/97 FVAERELVAEMERALVGLIETGQGEGDVRAMH-PLSAAR----LVQALFD
Rv3160c|M.tuberculosis_H37Rv FVAERELVAEMERALVGLIETGQGEGDVRAMH-PLSAAR----LVQALFD
MSMEG_1611|M.smegmatis_MC2_155 FDEERRGIDLFHDLVETLIRSGTDAGEFVDFE-ASFVLRAANGVMFETLR
TH_2975|M.thermoresistible__bu FGGFHRRRSELRAAYRDLAERVAAAGATPSSV-PDVVIDPDVVFRLVETL
MLBr_00815|M.leprae_Br4923 VAAQVRVATES--CIDAVFALISADSRLDPHR-ARMVAVGLVGISVDCAR
MMAR_4832|M.marinum_M IADMIT--TAYFEPVETLLRAGAADGSLVALDKPRAAAIALFGAVTISAL
. : .
MAV_0603|M.avium_104 RWYQPGGPLTAE---QVGQQYLAIVLGGITVDAKKD--------------
Mvan_5283|M.vanbaalenii_PYR-1 RWYQPGGPLTAQ---QVGRQYLSIVLGGITAEPTSKESTNG---------
Mflv_0719|M.gilvum_PYR-GCK RWLRPHGRRTAQ---EIAVEFSSALLRGLIRDETVRATSPLGVGIDVTAK
MUL_4731|M.ulcerans_Agy99 RWLRPHGRRTAR---EIAAEFSTALLRGLIRDESIRNQSPLGS-------
MAB_4574c|M.abscessus_ATCC_199 RWLNPSGRRSAQ---EIAVEFSTTLLRGLIRDEATRINDPLGVASATSLD
Mb3185c|M.bovis_AF2122/97 ALALPEFAVSPD---EIVEFAMTALLSDPDRLAEIRAAADALEIQTAPPD
Rv3160c|M.tuberculosis_H37Rv ALALPEFAVSPD---EIVEFAMTALLSDPDRLAEIRAAADALEIQTAPPD
MSMEG_1611|M.smegmatis_MC2_155 EQGGPAGRMRVQRPLQAADFVLRAVMVDPTDLPRIRAVTENRLVKGVLPA
TH_2975|M.thermoresistible__bu PNLRMDGLGEPDQP-RRTADLAVHVLGWRGDWPRLRSESATVAAAVGDCR
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKS---DAVEGTVQFAWGGLSHVPLTRL-------------
MMAR_4832|M.marinum_M TYLITDDALNEE---LIARTIHDVAFIGLRPR------------------
MAV_0603|M.avium_104 ---
Mvan_5283|M.vanbaalenii_PYR-1 ---
Mflv_0719|M.gilvum_PYR-GCK Q--
MUL_4731|M.ulcerans_Agy99 ---
MAB_4574c|M.abscessus_ATCC_199 GAR
Mb3185c|M.bovis_AF2122/97 RGL
Rv3160c|M.tuberculosis_H37Rv RGL
MSMEG_1611|M.smegmatis_MC2_155 GR-
TH_2975|M.thermoresistible__bu ---
MLBr_00815|M.leprae_Br4923 ---
MMAR_4832|M.marinum_M ---