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M. thermoresistible (build 8) TH_0537 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 1154784 - 1155425
length: 214

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0537--100% (214)transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_2023-1e-1836.00% (200) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3488-9e-1830.10% (196) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0281c-3e-0525.98% (204) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_3791-7e-6865.66% (198) TetR family transcriptional regulator
M. tuberculosis H37RvRv0275c-5e-0525.98% (204) TetR family transcriptional regulator
M. leprae Br4923MLBr_01070-9e-0532.47% (77) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_0835c-5e-0629.59% (98) TetR family transcriptional regulator
M. marinum MMMAR_3987-4e-5856.52% (207) putative transcriptional regulatory protein
M. avium 104MAV_1626-2e-5855.87% (213) hypothetical protein MAV_1626
M. smegmatis MC2 155MSMEG_2995-2e-6863.26% (215) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_3848-3e-5856.52% (207) putative transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2603-3e-6661.17% (206) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0281c|M.bovis_AF2122/97           ---------MTRSDRPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAE
Rv0275c|M.tuberculosis_H37Rv        ---------MTRSDRPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAE
Mflv_3791|M.gilvum_PYR-GCK          ----MSAKAQPDPTVRQDPAVRQDRAQSRAGRFMRSALDILG--ETGRTD
Mvan_2603|M.vanbaalenii_PYR-1       ----MSAKAQPSPTAQRDGAQQE----SRASRFMRSALDILG--ETGRTD
TH_0537|M.thermoresistible__bu      ---------MANPTS----ADTE----SRADRFLRSALTILG--ETGRTD
MSMEG_2995|M.smegmatis_MC2_155      ----MARPTQRSPDGAR--ADPE----DRTARFMRSALAILG--ETGRTD
MMAR_3987|M.marinum_M               ---------MAGPSE-----QVEA---TRADRFIKTAVEILG--ETGRTD
MUL_3848|M.ulcerans_Agy99           ---------MAGPSE-----QVEA---TRADRFIKTAVEILG--ETGRTD
MAV_1626|M.avium_104                ---------MAEPNE-----DVEI---TRGDRFIKTAVAILG--ETGRTD
MAB_0835c|M.abscessus_ATCC_199      ---------MTDTSAETTILTEDS----TDQRLLNAAERLFA--ERGVDA
MLBr_01070|M.leprae_Br4923          MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLA--ERPLGD
                                                                     :  .  ::.  :     

Mb0281c|M.bovis_AF2122/97           LTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAV
Rv0275c|M.tuberculosis_H37Rv        LTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAV
Mflv_3791|M.gilvum_PYR-GCK          FTVLEVVERSKTSLRAFYQHFSTKDELLLALVEKIMAEATERWRAETEQL
Mvan_2603|M.vanbaalenii_PYR-1       FTVLEVVERSKTSLRAFYQHFATKDELLLALVERVMVDATERWRAETDRM
TH_0537|M.thermoresistible__bu      FTVLEVVERSKTSLRSFYQHFSTKDELLLALIDTIMAESAARWRAELEGL
MSMEG_2995|M.smegmatis_MC2_155      FTVLEVVERSKTSLRSFYQHFSSKDELLLALIDRIMAESAQRWRADTEAL
MMAR_3987|M.marinum_M               FTVQEVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGL
MUL_3848|M.ulcerans_Agy99           FTVQEVVTRSKTSLRAFYQHFSSKDELLLALFDRTMSQTAQLWRAEAAGL
MAV_1626|M.avium_104                FTVQEVVARSKTSLRAFYQHFSSKDELLLALFDRTIAQSAQTWRAETAGL
MAB_0835c|M.abscessus_ATCC_199      VSLRAIMAAAGTNVASVHYHFGSKERLIEALLDRYLDQIEKRRFALLDVA
MLBr_01070|M.leprae_Br4923          FSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQL
                                    .::  :   :  .   .:  *  *: .:  :.:    .      *     

Mb0281c|M.bovis_AF2122/97           PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRA--ESSALF
Rv0275c|M.tuberculosis_H37Rv        PAREQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRA--ESSALF
Mflv_3791|M.gilvum_PYR-GCK          AGPDALRVLIDRISAPAQSSTQDSINRGLTYYNDHLLETRPK--EFATVL
Mvan_2603|M.vanbaalenii_PYR-1       TSDDALRLLIERISAPAESSTQDSINRGLTYYNDHLLETRPK--EFAKVL
TH_0537|M.thermoresistible__bu      PAAQALRTLIERICTPAGSSRQDYINRGLTSYNDRLADTLPR--EYARVL
MSMEG_2995|M.smegmatis_MC2_155      PGPEALRVLVEKITAPASSSTQDSINRGLTYYNDHLAESLPR--EYARVL
MMAR_3987|M.marinum_M               DSTAALKLVIDRISAQPESSTQDSLNRALSLYNQHLAETRPR--EYARVL
MUL_3848|M.ulcerans_Agy99           DSTAALKLVIDRISAQPESSTQDSLNRALSLYNQHLAETRPR--EYARVL
MAV_1626|M.avium_104                DSTAALKLVIDRVSQQPESSTQDSLNRALTLYNQHLAETRPR--EYARVL
MAB_0835c|M.abscessus_ATCC_199      ETARTLRAIAEAIVTPLSEIAEEGSTAWLSTLGKLLISGHPALIPMSVSF
MLBr_01070|M.leprae_Br4923          P-ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRR--LWSTVM
                                                :                    .            :  :

Mb0281c|M.bovis_AF2122/97           AMLSGQHAVDTLHAPANDHVK--------AVAHFAVGGVGQTISAWLAGD
Rv0275c|M.tuberculosis_H37Rv        AMLSGQHAVDTLHAPANDHVK--------AVAHFAVGGVGQTISAWLAGD
Mflv_3791|M.gilvum_PYR-GCK          APLHRLLGDILRRGIAEGSFR----------ADLDVDTDAAILMQTVLGT
Mvan_2603|M.vanbaalenii_PYR-1       APLHRLVADILRRGIDEGTFR----------ADLDVDTDAAILMHTVLGV
TH_0537|M.thermoresistible__bu      APLHQLIVDILRRGVAEGAFRGPGETAPDGGVDADLDAVAALIMQTALGA
MSMEG_2995|M.smegmatis_MC2_155      APLHDLIRGIVRRGIDAGDFH----------SGVEVDTTSALILQSVLGA
MMAR_3987|M.marinum_M               SPLHRLIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGA
MUL_3848|M.ulcerans_Agy99           SPLHRLIRDIVGQGITEGMFN----------PGLDVGAAAAIVMQTVLGA
MAV_1626|M.avium_104                SPLHRLIRDIVGQGITEGVFN----------PGLDVGAAAAIVMQTMMGA
MAB_0835c|M.abscessus_ATCC_199      QPQAARLQELILRLRPDATLP-----------SIRFGVTHAVTLTCVVLG
MLBr_01070|M.leprae_Br4923          QQWIDYNTAAIQAERKCGVAP-------------DTIPAEDLAVALQLMT
                                                                                      

Mb0281c|M.bovis_AF2122/97           VRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQP
Rv0275c|M.tuberculosis_H37Rv        VRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQP
Mflv_3791|M.gilvum_PYR-GCK          LRLR-ELGADLNGIPIEGSHVHTFCLRGLTPP------------------
Mvan_2603|M.vanbaalenii_PYR-1       LRLR-DLGAELNGVPIVGDHVHTFCVRGLTG-------------------
TH_0537|M.thermoresistible__bu      MRLR-ALGAELGGAPIDAELIYTFCLHGLARTTDS---------------
MSMEG_2995|M.smegmatis_MC2_155      MRLR-SLGVELNGTPIEGPHIYEFCVRSLSNPPTPDDQAFPRRP------
MMAR_3987|M.marinum_M               LRLR-WLGTELNATPIDAGELYEFCSRALGVRDAEESA-ASSLTELFAQI
MUL_3848|M.ulcerans_Agy99           LRLR-WLGTELNAMPIDAGELYEFCSRALGVRDTEESA-ASSLTELFAQI
MAV_1626|M.avium_104                QRLH-WLGAELNGTPVDAGQLYDFCSRALGIRDTDEDAGAPSLAELFGQI
MAB_0835c|M.abscessus_ATCC_199      DIAHTNRLMSLSGTYLDDGQMNAQLIDMVTAILAGPPDES----------
MLBr_01070|M.leprae_Br4923          ERVMAATFSDEKPLIPDKKVIDTLVHIWLASIYGS---------------
                                             .                  :                     

Mb0281c|M.bovis_AF2122/97           PSSARPARRS----------------------------------------
Rv0275c|M.tuberculosis_H37Rv        PSSARPARRS----------------------------------------
Mflv_3791|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0537|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3987|M.marinum_M               GMRQEPSHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYL
MUL_3848|M.ulcerans_Agy99           GMRQEPSHDDGFAMTMPVSPQVVNTSGALQGGLIATLADVAGGQLGLQYL
MAV_1626|M.avium_104                GMRPG-TRNGQFAMTMPVSPAVVNTSGALQGGLIATLVDVAGGQFGLDYL
MAB_0835c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01070|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0281c|M.bovis_AF2122/97           --------------------------------------------------
Rv0275c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_3791|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2603|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_0537|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2995|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3987|M.marinum_M               PPGAAMTTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSAD
MUL_3848|M.ulcerans_Agy99           PPGAAMTTADLFIRYLRPIRQGAARAVPRMLRAGRRALVMQVDIFGDSAD
MAV_1626|M.avium_104                RPGTTMTTADLFVRYLRPVRQGSAFAVPRMLRSGRRAMVMQVDIFGDGDD
MAB_0835c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_01070|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0281c|M.bovis_AF2122/97           ---------------------------
Rv0275c|M.tuberculosis_H37Rv        ---------------------------
Mflv_3791|M.gilvum_PYR-GCK          ---------------------------
Mvan_2603|M.vanbaalenii_PYR-1       ---------------------------
TH_0537|M.thermoresistible__bu      ---------------------------
MSMEG_2995|M.smegmatis_MC2_155      ---------------------------
MMAR_3987|M.marinum_M               ELAATATVNFAIIDRNDTTETG-----
MUL_3848|M.ulcerans_Agy99           ELAATATVNFAIIDRNDTTETG-----
MAV_1626|M.avium_104                ELLATATVNFAIIN-GDTPSSGLPPAE
MAB_0835c|M.abscessus_ATCC_199      ---------------------------
MLBr_01070|M.leprae_Br4923          ---------------------------