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MVHIAGRRMLVTGGQRGLGAAFASELLARGADRVYVTTRTPAPSSDARIVPVALDVTDPDSVRAATEIAD DVAIVVNNAGTNGPLPVLGTDIDAMREVFETNVFGPVRVTQAFAPILARQPDSALVNVHSVFSWLGGTGA YGASKAALWSLTNSLRVELAAQDTKVIGVHLSFADTDMTAGLDVFKIAPEYAAARVLDGLERDDAEVLVD DTSRDVKAALAGPVGELVLTL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2899 | - | - | 100% (231) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_1968 | - | 1e-48 | 47.35% (226) | putative oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_1595 | - | 5e-48 | 46.88% (224) | putative oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3199 | - | 5e-47 | 43.35% (233) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_5243 | - | 2e-19 | 38.46% (156) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3174 | - | 3e-47 | 43.35% (233) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-16 | 32.45% (188) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4428 | - | 2e-61 | 53.88% (219) | short chain dehydrogenase |
| M. marinum M | MMAR_1614 | - | 3e-17 | 33.33% (180) | short chain dehydrogenase |
| M. avium 104 | MAV_4982 | - | 7e-18 | 34.87% (195) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_2589 | - | 3e-17 | 34.74% (190) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3423 | - | 1e-17 | 33.89% (180) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0234 | - | 2e-42 | 43.72% (215) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1614|M.marinum_M --------------------MSTWLITGCSTGLGRALAEAVIDAGHHTVA
MUL_3423|M.ulcerans_Agy99 --------------------MSTWLITGCSTGLGRALAEAVIDAGHHTVA
MAV_4982|M.avium_104 -------------------MPKTWFITGSSRGLGRALTTAVLDHGDHVVA
Mflv_5243|M.gilvum_PYR-GCK --------------------MATVLITGCSSGYGRATALKFLAEGWNVVA
MSMEG_2899|M.smegmatis_MC2_155 ---------------MVHIAGRRMLVTGGQRGLGAAFASELLARGADRVY
MAB_4428|M.abscessus_ATCC_1997 -----------------MIKDTVVLVTGGRRGLGAAIVDEVLNRGARKVY
Mb3199|M.bovis_AF2122/97 ---------------MTSLAERTALVTGANRGMGREYVAQLLGRKVAKVY
Rv3174|M.tuberculosis_H37Rv ---------------MTSLAERTVLVTGANRGMGREYVAQLLGRKVAKVY
Mvan_0234|M.vanbaalenii_PYR-1 ---------------MTDTEHTTALVTGANRGLGRRFAEALVARG-AKVY
TH_2589|M.thermoresistible__bu -------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
.:** * * . : .
MMAR_1614|M.marinum_M TARSVGGVA---DLVQRSPERVLPLALDITEPDQITAAVQAAQQRFGGID
MUL_3423|M.ulcerans_Agy99 TARSVGGVA---DLAQRSPERVLPLALDITEPDQITAAMQAAQQRFGGID
MAV_4982|M.avium_104 TARRPAQLD---ELVDRYGPRIRACELDVTDRAAARRAIAAAVTAFGRID
Mflv_5243|M.gilvum_PYR-GCK TMRNPR------PDVLPASDRLRVSALDVTDPE----SIASAVEAAGPLD
MSMEG_2899|M.smegmatis_MC2_155 VTTRTP--------APSSDARIVPVALDVTDPD----SVRAATEIADDVA
MAB_4428|M.abscessus_ATCC_1997 STARAP--------FEDPRAQVVTKQLEVTSAE----SVDALARDLTDVE
Mb3199|M.bovis_AF2122/97 AATRNPL------AIDVSDPRVIPLQLDVTDAV----SVAEAADLATDVG
Rv3174|M.tuberculosis_H37Rv AATRNPL------AIDVSDPRVIPLQLDVTDAV----SVAEAADLATDVG
Mvan_0234|M.vanbaalenii_PYR-1 AAARRPE------TIDI--PGVVPIQLDITDPE----SVRRAAEQATDVT
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLRALGGDAIGVPTHLGDIDACEALVRRTVDEFGGID
MLBr_01807|M.leprae_Br4923 THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
.: . . :
MMAR_1614|M.marinum_M VLVNNAGYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSG
MUL_3423|M.ulcerans_Agy99 VLVNNAGYGYRAAVEEGDDAEVRDLFETHFFGTVALIKAVLPDMRARRSG
MAV_4982|M.avium_104 VVVNNAGYANSAPVEEVSDDDFRAQVETNFFGVVNVTKAALPVLHRQRAG
Mflv_5243|M.gilvum_PYR-GCK AVVNNAGIGAVGAFEATPMSTIRELFDTNTFGVMAMTQAVVPQMRERRSG
MSMEG_2899|M.smegmatis_MC2_155 IVVNNAGTNGPLPVLGTDIDAMREVFETNVFGPVRVTQAFAPILARQPDS
MAB_4428|M.abscessus_ATCC_1997 IVVNNAGVLHPDPLLTGDFDRIDATFQTNVFGPLRIARAFAPILKANGGG
Mb3199|M.bovis_AF2122/97 ILINNAGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSG-
Rv3174|M.tuberculosis_H37Rv ILINNAGISRASSVLDKDTSALRGELETNLFGPLALASAFADRIAERSG-
Mvan_0234|M.vanbaalenii_PYR-1 VVINNAGVSTRAGLLDGTLEDIRLEMDTHYFGTLAVTRAFVPVIERNGGG
TH_2589|M.thermoresistible__bu VLVNNAANALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKTSPHA
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
:: **. . .:.: * . : :
MMAR_1614|M.marinum_M AIVNISSIAVALT-PVGSGYYAAAKAAMEGMSGALHGELAPLGISVTVVE
MUL_3423|M.ulcerans_Agy99 AIVNISSIAVALT-PVGSGYYAAAKAAMEGMSGALHGELAPLGISVTVVE
MAV_4982|M.avium_104 HIVQISSVGGRVGGSPGIAAYQASKFAVAGFSEALAAEVAPLGIKVTIAE
Mflv_5243|M.gilvum_PYR-GCK VVVNVTSSTTLAP-MPLAAAYTASKSAIEGFTGSLALELGFFGVRAKLVE
MSMEG_2899|M.smegmatis_MC2_155 ALVNVHSVFSWLG-GTGA--YGASKAALWSLTNSLRVELAAQDTKVIGVH
MAB_4428|M.abscessus_ATCC_1997 AIVNIHSVLSWLG-GAGA--YGASKAAIWSVSNTLRLELEAQHTHVLGVH
Mb3199|M.bovis_AF2122/97 AIVNVSSVLAWLP-LGMS--YGVSKAAMWSATESMRIELAPRGVQVVGVY
Rv3174|M.tuberculosis_H37Rv AIVNVSSVLAWLP-LGMS--YGVSKAAMWSATESMRIELAPRGVQVVGVY
Mvan_0234|M.vanbaalenii_PYR-1 AILNVLSVLSWLH-PPTSGAYSAAKAAGWAMTDALRAELAPRGIHVAALH
TH_2589|M.thermoresistible__bu AVLNMVSVGAFLF-SPGTAMYSAGKAALMSFTRSMAAQFAPLGIRVNALA
MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSITANVVA
: : * * ..* . . : :: :. .
MMAR_1614|M.marinum_M PGAFRTDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAA
MUL_3423|M.ulcerans_Agy99 PGAFRTDFAGRSLVQSTRMINDYAATAGQRRKENDTMHGNQPGDPAKAAA
MAV_4982|M.avium_104 PGALRTEWAGSSMAVAT-VSPDYESTVGAMNRRRAGFNRNAPGDPARAAH
Mflv_5243|M.gilvum_PYR-GCK PG--------------------YGPGTQFTSNGVERMAGLIPAEYQDFAA
MSMEG_2899|M.smegmatis_MC2_155 LS-------------------------FADTDMTAGLDVF-KIAPEYAAA
MAB_4428|M.abscessus_ATCC_1997 AA-------------------------FIDTDMVSALPVP-KTPPSAIAA
Mb3199|M.bovis_AF2122/97 VG-------------------------LVDTDMGRFADAP-KSDPADVVR
Rv3174|M.tuberculosis_H37Rv VG-------------------------LVDTDMGRFADAP-KSDPADVVR
Mvan_0234|M.vanbaalenii_PYR-1 VG-------------------------FMDTDMVSYIPADQKTDPAVVAE
TH_2589|M.thermoresistible__bu PG-------------------------PVDTDMMRNNPQE--VVDMMAGA
MLBr_01807|M.leprae_Br4923 PG-------------------------FIDTEMTRAMDSK--YQEAALQA
.
MMAR_1614|M.marinum_M AIITAVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP
MUL_3423|M.ulcerans_Agy99 AIITAVESPAPPAFLLLGPDALMAYRHIAQRRDVEITDWEQLTAGTNLTP
MAV_4982|M.avium_104 AIIEVVIADDPPLRLLLGSDALSAALAKSHQQIAEANRWAELSKSIDYPP
Mflv_5243|M.gilvum_PYR-GCK PVFEEFRSPG----MVTTPDEVADVVFQAATDTSGRLRFAAGADAVALAQ
MSMEG_2899|M.smegmatis_MC2_155 RVLDGLERDDAEVLVDDTSRDVKAALAGPVGELVLTL-------------
MAB_4428|M.abscessus_ATCC_1997 RIIDALDKGDNEVLTDDLTVQIKSQLAGPVEKLAYRPGH-----------
Mb3199|M.bovis_AF2122/97 QVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN----------
Rv3174|M.tuberculosis_H37Rv QVLDGIEAGKEDVLADEMSRQVRASLNVPARERIARLMGN----------
Mvan_0234|M.vanbaalenii_PYR-1 LALDGLFAGQPEILADELTRNVKAQLSAAPA-------------------
TH_2589|M.thermoresistible__bu TLMKRLATPDEMVGAALLLTSDAGSYITGTVLIADGGGTPR---------
MLBr_01807|M.leprae_Br4923 IPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH--------
: .
MMAR_1614|M.marinum_M -----------
MUL_3423|M.ulcerans_Agy99 -----------
MAV_4982|M.avium_104 VATPHRAARSR
Mflv_5243|M.gilvum_PYR-GCK -----------
MSMEG_2899|M.smegmatis_MC2_155 -----------
MAB_4428|M.abscessus_ATCC_1997 -----------
Mb3199|M.bovis_AF2122/97 -----------
Rv3174|M.tuberculosis_H37Rv -----------
Mvan_0234|M.vanbaalenii_PYR-1 -----------
TH_2589|M.thermoresistible__bu -----------
MLBr_01807|M.leprae_Br4923 -----------