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PLSSRMPELAAFDVLLAIARTGSLGAAGRELGLTQQAVSARLASIEAQTGVRLVQRSSRGSQLTQAGVVV AEWADQLLEVAQRVDAGLAALRSESHTRLTVAASLTIAEQLMPRWLVSLHADARRRGVPTPEVILTAANS EDVIGAVRDGSAELGFIESPGTPRGLHTRVVARDELIVVVPPGHKWDRRSTPIGPAELNDTPLVSREAGS GTREALSTALRRALGDTTQAAPAIELSSAAAMRAAVAAGAGPAVMSRLAVEDDLTLGRLRAVPVAGLDLR RDLRAVWSGTRTPPAGAVRDLLGHIAAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2797 | - | - | 100% (310) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0544 | - | e-110 | 67.32% (306) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0708 | - | 4e-19 | 28.96% (297) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-108 | 66.34% (309) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 8e-14 | 26.17% (298) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-108 | 66.34% (309) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-13 | 23.74% (257) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 4e-57 | 43.32% (307) | LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 1e-112 | 65.37% (309) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 1e-110 | 65.70% (309) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 3e-07 | 27.15% (291) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-112 | 65.37% (309) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 7e-14 | 26.07% (303) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MSMEG_2797|M.smegmatis_MC2_155 MPLSSRMPELAAFDVLLAIARTGSLGAAGRELGLTQQAVSARLASIEAQT
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
: : ::::.. : *. : * : * : :*
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MSMEG_2797|M.smegmatis_MC2_155 GVRLVQRSSRGSQLTQAGVVVAEWADQLLEVAQRVDAGLAALRSESHTRL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSV
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
* * :* * : . : .
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MSMEG_2797|M.smegmatis_MC2_155 TVAASLTIAEQLMPRWLVSLHADARRRGVPTPEVILTAANSEDVIGAVRD
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALRARH-----ADVAVSLEVGNTQQVCELVRA
Mflv_3565|M.gilvum_PYR-GCK AIG-TVTLHPMNVAHLIAEFHADH-----PDVEITLGTATSDVLIAELGD
Mvan_3362|M.vanbaalenii_PYR-1 AIG-TVTLHPVDVARLMADFHAEH-----PGVEITLGTDTSDVLLAKLED
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAY-----PSTSFTLRQLYPDALTDAVFD
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRL-----PTLTLRVVEDQTEHLLTALRE
: :: : . . : .: :
MMAR_3419|M.marinum_M GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MAV_2151|M.avium_104 GSADLGFVENPGT--PKGLGSCVVGEDELVIVVPPTHKWARRSRVVTARE
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
MSMEG_2797|M.smegmatis_MC2_155 GSAELGFIESPGT--PRGLHTRVVARDELIVVVPPGHKWDRRSTPIGPAE
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHA--PTGLGGEVLGADELVIVVGPGHKWAHRRKPVTLRE
Mflv_3565|M.gilvum_PYR-GCK GRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLEQ
Mvan_3362|M.vanbaalenii_PYR-1 GRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLKQ
TH_3504|M.thermoresistible__bu GTVQLGLRRGVVP--TPELATAVIGYHRVRVAFVDSHPLAARESVDITEL
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGK-RRVPTTA
* . .: : : . . .. * :
MMAR_3419|M.marinum_M LAETPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MUL_2698|M.ulcerans_Agy99 LAEMPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MAV_2151|M.avium_104 LAQTPLVAREPHSGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAV
Mb2303c|M.bovis_AF2122/97 LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
Rv2282c|M.tuberculosis_H37Rv LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
MSMEG_2797|M.smegmatis_MC2_155 LNDTPLVSREAGSGTREALSTALRRALG-DTTQAAPAIELSSAAAMRAAV
MAB_3458c|M.abscessus_ATCC_199 LAITPLLMREPGSGTRD----TVWEVLSEVCQPATPAAELGSAAAIKAAA
Mflv_3565|M.gilvum_PYR-GCK LSRHPLISLPAGTGLRT----RLDTACAAAGLRPRIAFEATSPAELAELA
Mvan_3362|M.vanbaalenii_PYR-1 LCEYPVISLPAGTGLRS----RLDDACAAAGLRPRIAFEATSPLELADLA
TH_3504|M.thermoresistible__bu AREQVALWAPPGTSYYS---DFLMGACRRAGFEPDYVVSRVQGAATVAAP
MLBr_02041|M.leprae_Br4923 LAQLPLLLLDEGHCLRD----QTLDICRKSGVQAELANTRAASLATAVQC
: . .
MMAR_3419|M.marinum_M LAG-AGPAAMSRLAIADDLAVGRLRAIS--IPGLDLRRQLRAIWVGGRVP
MUL_2698|M.ulcerans_Agy99 LAG-AGPAAMSRLAIADDLAVGRLRAIS--IPGLDLRRQLRAIWVGGRVP
MAV_2151|M.avium_104 LAG-AGPAAMSRLAVADDLAVGRLHAVE--IPKLDLRRKFRAIWIGGRTP
Mb2303c|M.bovis_AF2122/97 LAG-AGPAAMSRLAIADDLAFGRLLAVD--IPALNLRRQLRAIWVGGRTP
Rv2282c|M.tuberculosis_H37Rv LAG-AGPAAMSRLAIADDLAFGRLLAVD--IPALNLRRQLRAIWVGGRTP
MSMEG_2797|M.smegmatis_MC2_155 AAG-AGPAVMSRLAVEDDLTLGRLRAVP--VAGLDLRRDLRAVWSGTRTP
MAB_3458c|M.abscessus_ATCC_199 ATG-LAPAVLSRLIAGPELSAGTLVEVKP-ADGTVFTRQFRAVWRPG-AP
Mflv_3565|M.gilvum_PYR-GCK RHG-LGVAILPQSMARGGSGLHALRLAP------ELRGRLVWAWRADGAN
Mvan_3362|M.vanbaalenii_PYR-1 RHG-LGVAILPRSMARGSAGLHPLRLSP------ELRGRLVWAWRTDISG
TH_3504|M.thermoresistible__bu LTT-GGIAFVTAAAGPTMNGRVQVVDLT-----PPLLVPVQALWQRH---
MLBr_02041|M.leprae_Br4923 VTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSA
. : :. : .
MMAR_3419|M.marinum_M PAGAIRELLSHITSGGE-----------
MUL_2698|M.ulcerans_Agy99 PAGAIRELLSHITSGGE-----------
MAV_2151|M.avium_104 PAGAIRDLLSHIIARTAASK--------
Mb2303c|M.bovis_AF2122/97 PAGAIRDLLSHITSRST-----------
Rv2282c|M.tuberculosis_H37Rv PAGAIRDLLSHITSRST-----------
MSMEG_2797|M.smegmatis_MC2_155 PAGAVRDLLGHIAAAR------------
MAB_3458c|M.abscessus_ATCC_199 PTGAARALVDIAALVD------------
Mflv_3565|M.gilvum_PYR-GCK PAARVLGERARAMAVSPGSGAPAVVPGA
Mvan_3362|M.vanbaalenii_PYR-1 PAARLLNARARAMIAATG--TPAVIPGA
TH_3504|M.thermoresistible__bu TLSAIRDRILEGLG--------------
MLBr_02041|M.leprae_Br4923 SYRQIAKIIGELISTEHHVRLVA-----
.