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MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQIGVTLAVRTTRGSQLTPAGLI VADWAARLLEVAHEIDAGLGSLRKEGRERIRVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATN SEHAIASVRDGSADLGFVENPGTPKGLGSCVVGEDELVIVVPPTHKWARRSRVVTARELAQTPLVAREPH SGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAVLAGAGPAAMSRLAVADDLAVGRLHAVEIPKLD LRRKFRAIWIGGRTPPAGAIRDLLSHIIARTAASK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2151 | - | - | 100% (315) | LysR-family protein transcriptional regulator |
| M. avium 104 | MAV_2838 | - | 3e-19 | 27.74% (274) | hydrogen peroxide-inducible genes activator |
| M. avium 104 | MAV_1538 | - | 1e-12 | 25.25% (301) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-138 | 80.71% (311) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 1e-12 | 26.05% (215) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-138 | 80.71% (311) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 3e-17 | 26.67% (255) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 7e-60 | 44.63% (307) | LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 1e-142 | 83.71% (307) | LysR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2797 | - | 1e-110 | 65.70% (309) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 7e-10 | 24.06% (266) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-142 | 83.71% (307) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 7e-14 | 26.09% (299) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
Mvan_1027|M.vanbaalenii_PYR-1 -------------------------MFSLARLSCFVAVAEELHFGRAAER
Mb2303c|M.bovis_AF2122/97 -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
Rv2282c|M.tuberculosis_H37Rv -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
MMAR_3419|M.marinum_M -------------------MPLSPRMPELGSFEIFLAIAQTGSLGAAARE
MUL_2698|M.ulcerans_Agy99 -------------------MPLSPRMPELASFEIFLAIAQTGSLGAAARE
MAV_2151|M.avium_104 -------------------MPLSPRMPELASFEAFLAIAETGSLGRAARE
MSMEG_2797|M.smegmatis_MC2_155 -------------------MPLSSRMPELAAFDVLLAIARTGSLGAAGRE
MAB_3458c|M.abscessus_ATCC_199 -------------------MALPPGTPDLGVLDLLVSVAETGSLGAAARQ
MLBr_02041|M.leprae_Br4923 -------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASF
TH_0172|M.thermoresistible__bu --------------------------MTPAQLRAFSAVVRLGSVRAAAQE
: : ::.. . *.
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
Mvan_1027|M.vanbaalenii_PYR-1 LHMTQPPLSRQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQL
Mb2303c|M.bovis_AF2122/97 LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
Rv2282c|M.tuberculosis_H37Rv LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
MMAR_3419|M.marinum_M LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MUL_2698|M.ulcerans_Agy99 LGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIVSEWAARLLEV
MAV_2151|M.avium_104 LGLTQQAISRRLATMEAQIGVTLAVRTTRGSQLTPAGLIVADWAARLLEV
MSMEG_2797|M.smegmatis_MC2_155 LGLTQQAVSARLASIEAQTGVRLVQRSSRGSQLTQAGVVVAEWADQLLEV
MAB_3458c|M.abscessus_ATCC_199 HGISQPAASMRIRALERRLRLVLLERGPTGSRLTDAGLAVVGYASPVLAA
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
TH_0172|M.thermoresistible__bu LGMSDAGISMHIAQLRKELDDPLFHRTKNGLSFTPGGLRLASRAVDILGL
: : * : :. * * .* * . * :
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELPAVALDI
Mvan_1027|M.vanbaalenii_PYR-1 AEGAAQTVKRIPAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVKLDL
Mb2303c|M.bovis_AF2122/97 ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
Rv2282c|M.tuberculosis_H37Rv ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
MMAR_3419|M.marinum_M AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MUL_2698|M.ulcerans_Agy99 AQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTA
MAV_2151|M.avium_104 AHEIDAGLGSLRKEGRERIRVAASQTISEQLMPHWLLSLQAEATRRGEAA
MSMEG_2797|M.smegmatis_MC2_155 AQRVDAGLAALRSESHTRLTVAASLTIAEQLMPRWLVSLHADARRRGVPT
MAB_3458c|M.abscessus_ATCC_199 AHEFVTGVAALHSDQAPRLVVAASRTIADHRIPLWLTALRARH-----AD
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLP-----T
TH_0172|M.thermoresistible__bu QRQTAIEVTEAAHG-RRLLRIAASHAFAEHAAPGLIDLFSSRAD-----D
: : : : *
Mflv_1356|M.gilvum_PYR-GCK HADLLTPDQ----CEGLRTGALDVGVLRPPAVG-GDVATRTIAAEPLVLA
Mvan_1027|M.vanbaalenii_PYR-1 R-EMVTAAQ----IEGLMTGELDLGMARPPLKR-PGLVSRPLLHEQLLAA
Mb2303c|M.bovis_AF2122/97 PEVILTATNSEHAIAAVRDGIADLGFIENPCPP-TGLGSVVVARDELVVV
Rv2282c|M.tuberculosis_H37Rv PEVILTATNSEHAIAAVRDGIADLGFIENPCPP-TGLGSVVVARDELVVV
MMAR_3419|M.marinum_M PQVILTATNSDHAIAAVRDGTADLGFVENPGPP-TGLGSRVVGHDDLVVV
MUL_2698|M.ulcerans_Agy99 PQVILTATNSDHAIAAVRDGTADLGFVENPGPP-TGLGSRVVGHDDLVVV
MAV_2151|M.avium_104 PQVILTATNSEHAIASVRDGSADLGFVENPGTP-KGLGSCVVGEDELVIV
MSMEG_2797|M.smegmatis_MC2_155 PEVILTAANSEDVIGAVRDGSAELGFIESPGTP-RGLHTRVVARDELIVV
MAB_3458c|M.abscessus_ATCC_199 VAVSLEVGNTQQVCELVRAGGASLGFIEGPHAP-TGLGGEVLGADELVIV
MLBr_02041|M.leprae_Br4923 LTLRVVEDQTEHLLTALREGALDAAMIALPVET-AGIAEIPIYDEDFVLA
TH_0172|M.thermoresistible__bu LSVELTVEPVSRFRDLLESRAVDVTLGPAVREPGPAIVVRPFLNYQIIAV
: : . . : . :: .
Mflv_1356|M.gilvum_PYR-GCK VSADHRLAAEP-VVSLADLRSEPFIGYT---GQDSAVNDAVTRSCRAAGF
Mvan_1027|M.vanbaalenii_PYR-1 LPEGHPLADMTRELTLIDLDGQDFVMYSP--VQARYFNELLISTFTIAGT
Mb2303c|M.bovis_AF2122/97 VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQ
Rv2282c|M.tuberculosis_H37Rv VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQ
MMAR_3419|M.marinum_M VPPGHKWTRRPSPVTARELAETPLVTREPRSGIRDSLTVALRQVLGEDMV
MUL_2698|M.ulcerans_Agy99 VPPGHKWTRRPSPVTARELAEMPLVTREPRSGIRDSLTVALRQVLGEDMV
MAV_2151|M.avium_104 VPPTHKWARRSRVVTARELAQTPLVAREPHSGIRDSLTVALRKVLGEDMQ
MSMEG_2797|M.smegmatis_MC2_155 VPPGHKWDRRSTPIGPAELNDTPLVSREAGSGTREALSTALRRALG-DTT
MAB_3458c|M.abscessus_ATCC_199 VGPGHKWAHRRKPVTLRELAITPLLMREPGSGTRD----TVWEVLSEVCQ
MLBr_02041|M.leprae_Br4923 LPPGHPLSGKRRVPTT-ALAQLPLLLLDEGHCLRDQTLDICRKSGVQAEL
TH_0172|M.thermoresistible__bu TSPSNPLAAAT--PTIAQLRAQSWMLGPSAGGIDGDVAAMLRRLEIPEAA
: * :
Mflv_1356|M.gilvum_PYR-GCK VPHREHSAPGTAVLLALVAADLGVSVVPASVRALPLHGVVFRDL----VD
Mvan_1027|M.vanbaalenii_PYR-1 TPRYVQYVTQVHTMLVLVRSGIGIALVPASAATLHPEGVVFRTIG--AFR
Mb2303c|M.bovis_AF2122/97 QAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVD-IPAL
Rv2282c|M.tuberculosis_H37Rv QAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVD-IPAL
MMAR_3419|M.marinum_M QASPVLELSSAAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAIS-IPGL
MUL_2698|M.ulcerans_Agy99 QASPVLELSSAAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAIS-IPGL
MAV_2151|M.avium_104 QAAPVLELTSAAAMRAAVLAGAGPAAMSRLAVADDLAVGRLHAVE-IPKL
MSMEG_2797|M.smegmatis_MC2_155 QAAPAIELSSAAAMRAAVAAGAGPAVMSRLAVEDDLTLGRLRAVP-VAGL
MAB_3458c|M.abscessus_ATCC_199 PATPAAELGSAAAIKAAAATGLAPAVLSRLIAGPELSAGTLVEVKPADGT
MLBr_02041|M.leprae_Br4923 AN---TRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPC
TH_0172|M.thermoresistible__bu QR----IFQSDSAAQEEVQRIGGVTLSIGFAVAKDLAAGRLARIK--GVQ
. . . : :
Mflv_1356|M.gilvum_PYR-GCK GGTVDLALAWRDGVDNPVVDAVVAVLAGALTSLDHPALQEQS--------
Mvan_1027|M.vanbaalenii_PYR-1 ERPVELDAVWRGDSTNP---ALLRVLKDVLPQQEWTT-------------
Mb2303c|M.bovis_AF2122/97 NLRRQLRAIWVGGRTPPAG-AIRDLLSHITSRST----------------
Rv2282c|M.tuberculosis_H37Rv NLRRQLRAIWVGGRTPPAG-AIRDLLSHITSRST----------------
MMAR_3419|M.marinum_M DLRRQLRAIWVGGRVPPAG-AIRELLSHITSGGE----------------
MUL_2698|M.ulcerans_Agy99 DLRRQLRAIWVGGRVPPAG-AIRELLSHITSGGE----------------
MAV_2151|M.avium_104 DLRRKFRAIWIGGRTPPAG-AIRDLLSHIIARTAASK-------------
MSMEG_2797|M.smegmatis_MC2_155 DLRRDLRAVWSGTRTPPAG-AVRDLLGHIAAAR-----------------
MAB_3458c|M.abscessus_ATCC_199 VFTRQFRAVWRPG-APPTG-AARALVDIAALVD-----------------
MLBr_02041|M.leprae_Br4923 PGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA----------
TH_0172|M.thermoresistible__bu ATAEWCVSTLSSAARQPAASELVRFITTPRCTQAMIRGTSEGVTRFRPKV
. .:
Mflv_1356|M.gilvum_PYR-GCK ------
Mvan_1027|M.vanbaalenii_PYR-1 ------
Mb2303c|M.bovis_AF2122/97 ------
Rv2282c|M.tuberculosis_H37Rv ------
MMAR_3419|M.marinum_M ------
MUL_2698|M.ulcerans_Agy99 ------
MAV_2151|M.avium_104 ------
MSMEG_2797|M.smegmatis_MC2_155 ------
MAB_3458c|M.abscessus_ATCC_199 ------
MLBr_02041|M.leprae_Br4923 ------
TH_0172|M.thermoresistible__bu HVTLWS