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ALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRLRLVLLERGPTGSRLTDAGLAV VGYASPVLAAAHEFVTGVAALHSDQAPRLVVAASRTIADHRIPLWLTALRARHADVAVSLEVGNTQQVCE LVRAGGASLGFIEGPHAPTGLGGEVLGADELVIVVGPGHKWAHRRKPVTLRELAITPLLMREPGSGTRDT VWEVLSEVCQPATPAAELGSAAAIKAAAATGLAPAVLSRLIAGPELSAGTLVEVKPADGTVFTRQFRAVW RPGAPPTGAARALVDIAALVD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3458c | - | - | 100% (302) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4409 | - | 2e-16 | 26.84% (272) | hydrogen peroxide-inducible genes activator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 2e-16 | 29.97% (297) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 5e-56 | 42.35% (307) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 8e-14 | 29.14% (278) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 5e-56 | 42.35% (307) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 6e-14 | 25.32% (233) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 3e-60 | 44.59% (305) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 6e-60 | 44.63% (307) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2797 | - | 5e-57 | 43.32% (307) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 2e-07 | 23.94% (259) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2698 | - | 5e-59 | 43.93% (305) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 3e-16 | 29.08% (251) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MSMEG_2797|M.smegmatis_MC2_155 MPLSSRMPELAAFDVLLAIARTGSLGAAGRELGLTQQAVSARLASIEAQT
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_0172|M.thermoresistible__bu -------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
: : ::.. . *. : : * : :.
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGSV
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVRGAV
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MSMEG_2797|M.smegmatis_MC2_155 GVRLVQRSSRGSQLTQAGVVVAEWADQLLEVAQRVDAGLAALRSESHTRL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHG-RRLL
* * .* * : * : :
Mflv_3565|M.gilvum_PYR-GCK AIG-TVTLHPMNVAHLIAEFHADH-----PDVEITLGTATSDVLIAELGD
Mvan_3362|M.vanbaalenii_PYR-1 AIG-TVTLHPVDVARLMADFHAEH-----PGVEITLGTDTSDVLLAKLED
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MSMEG_2797|M.smegmatis_MC2_155 TVAASLTIAEQLMPRWLVSLHADARRRGVPTPEVILTAANSEDVIGAVRD
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALRARH-----ADVAVSLEVGNTQQVCELVRA
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRL-----PTLTLRVVEDQTEHLLTALRE
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFSSRA-----DDLSVELTVEPVSRFRDLLES
: :. . : : : : . :
Mflv_3565|M.gilvum_PYR-GCK GRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLEQ
Mvan_3362|M.vanbaalenii_PYR-1 GRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLKQ
MMAR_3419|M.marinum_M GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MAV_2151|M.avium_104 GSADLGFVENPGT--PKGLGSCVVGEDELVIVVPPTHKWARRSRVVTARE
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
MSMEG_2797|M.smegmatis_MC2_155 GSAELGFIESPGT--PRGLHTRVVARDELIVVVPPGHKWDRRSTPIGPAE
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHA--PTGLGGEVLGADELVIVVGPGHKWAHRRKPVTLRE
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGK-RRVPTTA
TH_0172|M.thermoresistible__bu RAVDVTLGPAVREP-GPAIVVRPFLNYQIIAVTSPSNPLAAA--TPTIAQ
. : .: . . . :
Mflv_3565|M.gilvum_PYR-GCK LSRHPLISLPAGTGLRT----RLDTACAAAGLRPRIAFEATSPAELAELA
Mvan_3362|M.vanbaalenii_PYR-1 LCEYPVISLPAGTGLRS----RLDDACAAAGLRPRIAFEATSPLELADLA
MMAR_3419|M.marinum_M LAETPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MUL_2698|M.ulcerans_Agy99 LAEMPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MAV_2151|M.avium_104 LAQTPLVAREPHSGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAV
Mb2303c|M.bovis_AF2122/97 LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
Rv2282c|M.tuberculosis_H37Rv LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
MSMEG_2797|M.smegmatis_MC2_155 LNDTPLVSREAGSGTREALSTALRRALG-DTTQAAPAIELSSAAAMRAAV
MAB_3458c|M.abscessus_ATCC_199 LAITPLLMREPGSGTRD----TVWEVLSEVCQPATPAAELGSAAAIKAAA
MLBr_02041|M.leprae_Br4923 LAQLPLLLLDEGHCLRD----QTLDICRKSGVQAELANTRAASLATAVQC
TH_0172|M.thermoresistible__bu LRAQSWMLGPSAGGIDG---DVAAMLRRLEIPEAAQRIFQSDSAAQEEVQ
* . : . .
Mflv_3565|M.gilvum_PYR-GCK RHG-LGVAILPQSMARGGSGLHALRLAP-----ELRGR-LVWAWRADGAN
Mvan_3362|M.vanbaalenii_PYR-1 RHG-LGVAILPRSMARGSAGLHPLRLSP-----ELRGR-LVWAWRTDISG
MMAR_3419|M.marinum_M LAG-AGPAAMSRLAIADDLAVGRLRAIS-IPGLDLRRQ-LRAIWVGGRVP
MUL_2698|M.ulcerans_Agy99 LAG-AGPAAMSRLAIADDLAVGRLRAIS-IPGLDLRRQ-LRAIWVGGRVP
MAV_2151|M.avium_104 LAG-AGPAAMSRLAVADDLAVGRLHAVE-IPKLDLRRK-FRAIWIGGRTP
Mb2303c|M.bovis_AF2122/97 LAG-AGPAAMSRLAIADDLAFGRLLAVD-IPALNLRRQ-LRAIWVGGRTP
Rv2282c|M.tuberculosis_H37Rv LAG-AGPAAMSRLAIADDLAFGRLLAVD-IPALNLRRQ-LRAIWVGGRTP
MSMEG_2797|M.smegmatis_MC2_155 AAG-AGPAVMSRLAVEDDLTLGRLRAVP-VAGLDLRRD-LRAVWSGTRTP
MAB_3458c|M.abscessus_ATCC_199 ATG-LAPAVLSRLIAGPELSAGTLVEVKPADGTVFTRQ-FRAVWRPG-AP
MLBr_02041|M.leprae_Br4923 VTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSA
TH_0172|M.thermoresistible__bu RIG--GVTLSIGFAVAKDLAAGRLARIK--GVQATAEWCVSTLSSAARQP
* . : * .
Mflv_3565|M.gilvum_PYR-GCK PAARVLGERARAMAVSPGSGAPAVVPGA-----------
Mvan_3362|M.vanbaalenii_PYR-1 PAARLLNARARAMIAATG--TPAVIPGA-----------
MMAR_3419|M.marinum_M PAGAIRELLSHITSGGE----------------------
MUL_2698|M.ulcerans_Agy99 PAGAIRELLSHITSGGE----------------------
MAV_2151|M.avium_104 PAGAIRDLLSHIIARTAASK-------------------
Mb2303c|M.bovis_AF2122/97 PAGAIRDLLSHITSRST----------------------
Rv2282c|M.tuberculosis_H37Rv PAGAIRDLLSHITSRST----------------------
MSMEG_2797|M.smegmatis_MC2_155 PAGAVRDLLGHIAAAR-----------------------
MAB_3458c|M.abscessus_ATCC_199 PTGAARALVDIAALVD-----------------------
MLBr_02041|M.leprae_Br4923 SYRQIAKIIGELISTEHHVRLVA----------------
TH_0172|M.thermoresistible__bu AASELVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
.