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VQLSARMPDLMALEVLLAVARKGSLSAASRECGLTQQAISARIAALERQTGVRLVTRTKTGSRLTSSGVL AAQWADRLLDVAHEVDAGLATLRDNSKTQLRITASLTVAEQLLPRWLVSWREAVTRQGGPAPDLILTAAN SEHVLAAVRGDHADLGFIESRGAPRGLRSSVVAHDELVVVVPPGHTWARRSRPIAPEELAATPLVTREQG SGTREFLASVLKGVAGAEQVRPALELSSAAAVRAAVLADAGPAVLSRLAVADDLQLGRLRAVDVTGLDLR RALRAVWLGTRTPPAGAARDLLSHIASVCKGSPRHAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0544 | - | - | 100% (317) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2797 | - | e-110 | 67.32% (306) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 5e-16 | 27.61% (297) | LysR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-101 | 61.24% (307) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 2e-12 | 26.05% (311) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-101 | 61.24% (307) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-14 | 26.09% (253) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 8e-55 | 43.71% (302) | LysR family transcriptional regulator |
| M. marinum M | MMAR_3419 | - | 1e-100 | 59.28% (307) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 6e-98 | 59.34% (305) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 1e-07 | 25.46% (271) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-100 | 58.96% (307) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 2e-13 | 26.67% (300) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
Mvan_3362|M.vanbaalenii_PYR-1 -------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLERQV
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MSMEG_0544|M.smegmatis_MC2_155 MQLSARMPDLMALEVLLAVARKGSLSAASRECGLTQQAISARIAALERQT
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
TH_0172|M.thermoresistible__bu -------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
: : ::.. . *: : : * : :.
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAG------
Mvan_3362|M.vanbaalenii_PYR-1 GQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVAN------
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MSMEG_0544|M.smegmatis_MC2_155 GVRLVTRTKTGSRLTSSGVLAAQWADRLLDVAHEVDAGLATLRDNSKTQL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHG-RRLL
* * .* * * :
Mflv_3565|M.gilvum_PYR-GCK LLRGSVAIGTVTLHPMNVAHLIAEFHADHPDVEITLGTATSDVLIAELGD
Mvan_3362|M.vanbaalenii_PYR-1 LVRGAVAIGTVTLHPVDVARLMADFHAEHPGVEITLGTDTSDVLLAKLED
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MSMEG_0544|M.smegmatis_MC2_155 RITASLTVAEQLLPRWLVSWREAVTRQGGPAPDLILTAANSEHVLAAVRG
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALR---ARHADVA--VSLEVGNTQQVCELVRA
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLT-----HRLPTLTLRVVEDQTEHLLTALRE
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFS-----SRADDLSVELTVEPVSRFRDLLES
: :.. : : . :
Mflv_3565|M.gilvum_PYR-GCK GRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLEQ
Mvan_3362|M.vanbaalenii_PYR-1 GRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR-KSLSLKQ
MMAR_3419|M.marinum_M GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGP--PTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARE
MAV_2151|M.avium_104 GSADLGFVENPGT--PKGLGSCVVGEDELVIVVPPTHKWARRSRVVTARE
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARRSRVVSARE
MSMEG_0544|M.smegmatis_MC2_155 DHADLGFIESRGA--PRGLRSSVVAHDELVVVVPPGHTWARRSRPIAPEE
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHA--PTGLGGEVLGADELVIVVGPGHKWAHRRKPVTLRE
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGK-RRVPTTA
TH_0172|M.thermoresistible__bu RAVDVTLGPAVREP-GPAIVVRPFLNYQIIAVTSPSNPLAAA--TPTIAQ
. : .: . . . : : .
Mflv_3565|M.gilvum_PYR-GCK LSRHPLISLPAGTGLRT----RLDTACAAAGLRPRIAFEATSPAELAELA
Mvan_3362|M.vanbaalenii_PYR-1 LCEYPVISLPAGTGLRS----RLDDACAAAGLRPRIAFEATSPLELADLA
MMAR_3419|M.marinum_M LAETPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MUL_2698|M.ulcerans_Agy99 LAEMPLVTREPRSGIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAV
MAV_2151|M.avium_104 LAQTPLVAREPHSGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAV
Mb2303c|M.bovis_AF2122/97 LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
Rv2282c|M.tuberculosis_H37Rv LAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAV
MSMEG_0544|M.smegmatis_MC2_155 LAATPLVTREQGSGTREFLASVLKGVAG--AEQVRPALELSSAAAVRAAV
MAB_3458c|M.abscessus_ATCC_199 LAITPLLMREPGSGTRD----TVWEVLSEVCQPATPAAELGSAAAIKAAA
MLBr_02041|M.leprae_Br4923 LAQLPLLLLDEGHCLRD----QTLDICRKSGVQAELANTRAASLATAVQC
TH_0172|M.thermoresistible__bu LRAQSWMLGPSAGGIDGDVAAMLRRLEIPEAAQRIFQSDSAAQEEVQRIG
* . : :
Mflv_3565|M.gilvum_PYR-GCK RHG--LGVAILPQSMARGGSGLHALRLAP-----ELRGRLVWAWRADGAN
Mvan_3362|M.vanbaalenii_PYR-1 RHG--LGVAILPRSMARGSAGLHPLRLSP-----ELRGRLVWAWRTDISG
MMAR_3419|M.marinum_M LAG--AGPAAMSRLAIADDLAVGRLRAIS-IPGLDLRRQLRAIWVGGRVP
MUL_2698|M.ulcerans_Agy99 LAG--AGPAAMSRLAIADDLAVGRLRAIS-IPGLDLRRQLRAIWVGGRVP
MAV_2151|M.avium_104 LAG--AGPAAMSRLAVADDLAVGRLHAVE-IPKLDLRRKFRAIWIGGRTP
Mb2303c|M.bovis_AF2122/97 LAG--AGPAAMSRLAIADDLAFGRLLAVD-IPALNLRRQLRAIWVGGRTP
Rv2282c|M.tuberculosis_H37Rv LAG--AGPAAMSRLAIADDLAFGRLLAVD-IPALNLRRQLRAIWVGGRTP
MSMEG_0544|M.smegmatis_MC2_155 LAD--AGPAVLSRLAVADDLQLGRLRAVD-VTGLDLRRALRAVWLGTRTP
MAB_3458c|M.abscessus_ATCC_199 ATG--LAPAVLSRLIAGPELSAGTLVEVKPADGTVFTRQFRAVWRPG-AP
MLBr_02041|M.leprae_Br4923 VTGG-LGVTLLPQSAAPVESVRSKLGLAQ-FAAPCPGRRIGLAFRSASGR
TH_0172|M.thermoresistible__bu GVTLSIGFAVAKDLAAGRLARIKGVQATAEWCVSTLSSAARQPAASELVR
. : :
Mflv_3565|M.gilvum_PYR-GCK PAARVLGERARAMAVSPGSGAPAVVPGA----
Mvan_3362|M.vanbaalenii_PYR-1 PAARLLNARARAMIAATG--TPAVIPGA----
MMAR_3419|M.marinum_M PAGAIRELLSHITSGGE---------------
MUL_2698|M.ulcerans_Agy99 PAGAIRELLSHITSGGE---------------
MAV_2151|M.avium_104 PAGAIRDLLSHIIARTAASK------------
Mb2303c|M.bovis_AF2122/97 PAGAIRDLLSHITSRST---------------
Rv2282c|M.tuberculosis_H37Rv PAGAIRDLLSHITSRST---------------
MSMEG_0544|M.smegmatis_MC2_155 PAGAARDLLSHIASVCKGSPRHAP--------
MAB_3458c|M.abscessus_ATCC_199 PTGAARALVDIAALVD----------------
MLBr_02041|M.leprae_Br4923 SASYRQIAKIIGELISTEHHVRLVA-------
TH_0172|M.thermoresistible__bu FITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS