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PLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHTGVTLAVRTTRGSQLTPAGLIV SEWAARLLEVAQEIDAGLGSLRKEGRERIRVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNS DHAIAAVRDGTADLGFVENPGPPTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARELAETPLVTREPRS GIRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAVLAGAGPAAMSRLAIADDLAVGRLRAISIPGLDL RRQLRAIWVGGRVPPAGAIRELLSHITSGGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3419 | - | - | 100% (312) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 3e-15 | 29.19% (209) | hydrogen peroxide-inducible genes activator, OxyR |
| M. marinum M | MMAR_0653 | - | 1e-14 | 26.14% (306) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-138 | 81.23% (309) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1833 | - | 2e-13 | 29.45% (275) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-138 | 81.23% (309) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 7e-17 | 27.56% (254) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 2e-60 | 44.59% (305) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 1e-142 | 83.71% (307) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2797 | - | 1e-112 | 65.37% (309) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-09 | 27.54% (276) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 1e-171 | 99.36% (312) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 8e-12 | 27.80% (205) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3419|M.marinum_M MPLSPRMPELGSFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MUL_2698|M.ulcerans_Agy99 MPLSPRMPELASFEIFLAIAQTGSLGAAARELGLTQQAVSKRLAAMEAHT
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MSMEG_2797|M.smegmatis_MC2_155 MPLSSRMPELAAFDVLLAIARTGSLGAAGRELGLTQQAVSARLASIEAQT
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
Mvan_1027|M.vanbaalenii_PYR-1 ------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSRQVQQLENEL
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
Mflv_1833|M.gilvum_PYR-GCK -------MDTHRLKYFLRIAEEGSITRAASLLGMAQPALSRQLQLLEEDL
: :: :.. : *. : * . * : :*
MMAR_3419|M.marinum_M GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MUL_2698|M.ulcerans_Agy99 GVTLAVRTTRGSQLTPAGLIVSEWAARLLEVAQEIDAGLGSLRKEGRERI
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MSMEG_2797|M.smegmatis_MC2_155 GVRLVQRSSRGSQLTQAGVVVAEWADQLLEVAQRVDAGLAALRSESHTRL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
Mvan_1027|M.vanbaalenii_PYR-1 GVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKRIPAGDLGTV
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
Mflv_1833|M.gilvum_PYR-GCK GVALFRRNRRGVELTDAGERLRSSTAAPLRQLELAVQYAAFPLARLKRAM
* * :* * . :
MMAR_3419|M.marinum_M RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MUL_2698|M.ulcerans_Agy99 RVAASQTIAEQLMPHWLLALQDAAKRRGTTAPQVILTATNSDHAIAAVRD
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MSMEG_2797|M.smegmatis_MC2_155 TVAASLTIAEQLMPRWLVSLHADARRRGVPTPEVILTAANSEDVIGAVRD
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALRARH-----ADVAVSLEVGNTQQVCELVRA
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLP-----TLTLRVVEDQTEHLLTALRE
Mvan_1027|M.vanbaalenii_PYR-1 VVGFTAASAHAVLPRLLERARERLP-----DVKLDLREMVTAAQIEGLMT
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYP-----STSFTLRQLYPDALTDAVFD
Mflv_1833|M.gilvum_PYR-GCK LIGIPESAIDVLAAPLMTRLGSAFP-----DAQFAVTVGSTDHLVEAMLK
: : : . : . :
MMAR_3419|M.marinum_M GTADLGFVENPGPPTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARELA
MUL_2698|M.ulcerans_Agy99 GTADLGFVENPGPPTGLGSRVVGHDDLVVVVPPGHKWTRRPSPVTARELA
MAV_2151|M.avium_104 GSADLGFVENPGTPKGLGSCVVGEDELVIVVPPTHKWARRSRVVTARELA
Mb2303c|M.bovis_AF2122/97 GIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELA
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENPCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELA
MSMEG_2797|M.smegmatis_MC2_155 GSAELGFIESPGTPRGLHTRVVARDELIVVVPPGHKWDRRSTPIGPAELN
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHAPTGLGGEVLGADELVIVVGPGHKWAHRRKPVTLRELA
MLBr_02041|M.leprae_Br4923 GALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRR-VPTTALA
Mvan_1027|M.vanbaalenii_PYR-1 GELDLGMARPPLKRPGLVSRPLLHEQLLAALPEGHPLADMTRELTLIDLD
TH_3504|M.thermoresistible__bu GTVQLGLRRGVVPTPELATAVIGYHRVRVAFVDSHPLAARES-VDITELA
Mflv_1833|M.gilvum_PYR-GCK GSVDIALIN-PVPDDRVFYREILTEEFVLVGGPDSPLE-PEKPLQFADLV
* . .: : : . . . : *
MMAR_3419|M.marinum_M ETPLVTREPRSG-IRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAVL
MUL_2698|M.ulcerans_Agy99 EMPLVTREPRSG-IRDSLTVALRQVLGEDMVQASPVLELSSAAAMRAAVL
MAV_2151|M.avium_104 QTPLVAREPHSG-IRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRAAVL
Mb2303c|M.bovis_AF2122/97 QTPLVTREPNSG-IRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
Rv2282c|M.tuberculosis_H37Rv QTPLVTREPNSG-IRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
MSMEG_2797|M.smegmatis_MC2_155 DTPLVSREAGSG-TREALSTALRRALG-DTTQAAPAIELSSAAAMRAAVA
MAB_3458c|M.abscessus_ATCC_199 ITPLLMREPGSG-TRD----TVWEVLSEVCQPATPAAELGSAAAIKAAAA
MLBr_02041|M.leprae_Br4923 QLPLLLLDEGHC-LRDQTLDICRKSGVQAELANTRAASLATAVQCVTGGL
Mvan_1027|M.vanbaalenii_PYR-1 GQDFVMYSPVQARYFNELLISTFTIAGTTPRYVQYVTQVHTMLVLVRSGI
TH_3504|M.thermoresistible__bu REQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATVAAPLTTG
Mflv_1833|M.gilvum_PYR-GCK ELPLVVPRSTTGLGQALYNAALRAKVTIDYRITTDSTRVMVCLIESGLAY
.
MMAR_3419|M.marinum_M AGAGPAAMSRLAIADDLAVGRLRAIS---IPGLDLRRQLRAIWVGGRVPP
MUL_2698|M.ulcerans_Agy99 AGAGPAAMSRLAIADDLAVGRLRAIS---IPGLDLRRQLRAIWVGGRVPP
MAV_2151|M.avium_104 AGAGPAAMSRLAVADDLAVGRLHAVE---IPKLDLRRKFRAIWIGGRTPP
Mb2303c|M.bovis_AF2122/97 AGAGPAAMSRLAIADDLAFGRLLAVD---IPALNLRRQLRAIWVGGRTPP
Rv2282c|M.tuberculosis_H37Rv AGAGPAAMSRLAIADDLAFGRLLAVD---IPALNLRRQLRAIWVGGRTPP
MSMEG_2797|M.smegmatis_MC2_155 AGAGPAVMSRLAVEDDLTLGRLRAVP---VAGLDLRRDLRAVWSGTRTPP
MAB_3458c|M.abscessus_ATCC_199 TGLAPAVLSRLIAGPELSAGTLVEVKP--ADGTVFTRQFRAVWRPG-APP
MLBr_02041|M.leprae_Br4923 GVTLLPQSAAPVESVRSKLGLAQFAAP--CPGRRIGLAFRS--ASGRSAS
Mvan_1027|M.vanbaalenii_PYR-1 GIALVPASAATLHPEGVVFRTIGAFR-------ERPVELDAVWRGDSTNP
TH_3504|M.thermoresistible__bu GIAFVTAAAGPTMNGRVQVVDLTPPL---------LVPVQALWQRH----
Mflv_1833|M.gilvum_PYR-GCK GVLPLSACGREFAESRLRYSRICEPVLTQQLGVAATEQLDLPRELVVKVG
. . .
MMAR_3419|M.marinum_M AGAIRELLSHITSGGE---------------
MUL_2698|M.ulcerans_Agy99 AGAIRELLSHITSGGE---------------
MAV_2151|M.avium_104 AGAIRDLLSHIIARTAASK------------
Mb2303c|M.bovis_AF2122/97 AGAIRDLLSHITSRST---------------
Rv2282c|M.tuberculosis_H37Rv AGAIRDLLSHITSRST---------------
MSMEG_2797|M.smegmatis_MC2_155 AGAVRDLLGHIAAAR----------------
MAB_3458c|M.abscessus_ATCC_199 TGAARALVDIAALVD----------------
MLBr_02041|M.leprae_Br4923 YRQIAKIIGELISTEHHVRLVA---------
Mvan_1027|M.vanbaalenii_PYR-1 A-LLRVLKDVLPQQEWTT-------------
TH_3504|M.thermoresistible__bu --TLSAIRDRILEGLG---------------
Mflv_1833|M.gilvum_PYR-GCK NALREEIAALIRSGSWRADLLSPEPWSPRRV
: