For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRRRPDVTLAQLRYFVKAATYLSMTKAADELHIAQSAVSAAISQLEQQIGTQLFIRHRARGLALTAAGEE MLHDTRALLAHLDEVLDNATGRVDRVHGTVRLACFVTLTPFVLPRLLPDLGTRHPDLEVEVIETSADAVR TVLRNGTAELALTYDLALGAGVDAEYLGVAAPYVALPPDHRLADRKSIRLTELAEEPMVLLDLPDSRDYF ESMLAKAGVTPRIRYRSASYEAVRGLVARGHGFSILNQIPAHRGTYDGGEVSVVPIRDELPGLPIVLARL RSVRSTARARAVADAAREIFADRPGRRAGPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1678 | - | - | 100% (311) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_0817 | - | 2e-50 | 35.10% (302) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0708 | - | 1e-23 | 28.42% (278) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 2e-10 | 28.30% (265) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 5e-22 | 31.50% (254) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-10 | 28.30% (265) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 1e-22 | 31.30% (246) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0055c | - | 8e-23 | 29.41% (289) | DNA-binding transcriptional regulator CynR |
| M. marinum M | MMAR_4157 | - | 6e-23 | 31.85% (248) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2838 | - | 3e-25 | 33.74% (243) | hydrogen peroxide-inducible genes activator |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-16 | 27.73% (220) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 2e-22 | 31.85% (248) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4518 | - | 1e-26 | 33.71% (267) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1678|M.smegmatis_MC2_155 -MRRRPDVTLAQLRYFVKAATYLSMTKAADELHIAQSAVSAAISQLEQQI
Mvan_4518|M.vanbaalenii_PYR-1 -------MTLRQLRYFAVLGHELNYRRAAEKLFITQPALSTAIKQLEHQF
MMAR_4157|M.marinum_M -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
MUL_4020|M.ulcerans_Agy99 -------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSRAITLLEAEI
Mflv_3565|M.gilvum_PYR-GCK -------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLERSV
MAB_0055c|M.abscessus_ATCC_199 -------MELRHIRYLLAVADHANFTRAAESLHISQPTLSQQIKQLERTL
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
MAV_2838|M.avium_104 MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGL
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
: : : *: : * ::* : :* .
MSMEG_1678|M.smegmatis_MC2_155 GTQLFIRHRARGLALTAAGEEMLHDTRALLAHLDEVLDNATGRVDRVHGT
Mvan_4518|M.vanbaalenii_PYR-1 GVVLFHRN-TREVALTDLGAAWLPQVQQALSGVDAVVDNLIMLSGTRRGV
MMAR_4157|M.marinum_M GVQLFTRR-GRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGT
MUL_4020|M.ulcerans_Agy99 GVQLFTRR-GRTNELNRYGQALLVGSRLAQRSVSSAIDNVRELAGVSGGT
Mflv_3565|M.gilvum_PYR-GCK GQPLLTRT-SREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLRGS
MAB_0055c|M.abscessus_ATCC_199 GVILLDRS-GRAVRLTDAGEAYAQHARLALRDLDAGERAVHDMHDLSRGH
MLBr_02041|M.leprae_Br4923 GVQLIERS-TRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGG
MAV_2838|M.avium_104 GTQLVERS-TRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAG
Mb2303c|M.bovis_AF2122/97 GVRLAIRT-TRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQR
Rv2282c|M.tuberculosis_H37Rv GVRLAIRT-TRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQR
TH_3504|M.thermoresistible__bu GADLFTRD-GRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAH
* * * * :. *
MSMEG_1678|M.smegmatis_MC2_155 VRLACFVTLTPFVLPRLLPDLGTRHPD-----LEVEVIETSADAVRTVLR
Mvan_4518|M.vanbaalenii_PYR-1 LRVGYLIGTGADLLFRLVRHFEAAYPD-----VTVEPIEFDFADPTAGLA
MMAR_4157|M.marinum_M VALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLV
MUL_4020|M.ulcerans_Agy99 VALGFLHSLGMQTVPHLIRLHHSRFPQ-----ARFELHQRSGQGVLSDLV
Mflv_3565|M.gilvum_PYR-GCK VAIG-TVTLHPMNVAHLIAEFHADHPD-----VEITLGTATSDVLIAELG
MAB_0055c|M.abscessus_ATCC_199 LRIAMTPTFTAYFIGPLVHRFHSAHPG-----ITLTVRETTQDRIEADLL
MLBr_02041|M.leprae_Br4923 MRLGLIPTVAPYVLPTMLTGLTHRLPT-----LTLRVVEDQTEHLLTALR
MAV_2838|M.avium_104 MRLGLIPTVAPYVLPTVLAGIAERRPG-----LTLRVTEDQTERLLAVLR
Mb2303c|M.bovis_AF2122/97 IRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVR
Rv2282c|M.tuberculosis_H37Rv IRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVR
TH_3504|M.thermoresistible__bu YVIGHTPALSGAEAYALIEPAVTAYPS-----TSFTLRQLYPDALTDAVF
: : . :
MSMEG_1678|M.smegmatis_MC2_155 NGTAELALTYDLALG--AGVDAEYLGVAAPYVALPPDHRLADR-KSIRLT
Mvan_4518|M.vanbaalenii_PYR-1 DGTTEVAIIRPPVDL--PEHRMLILDSESWVACLPRDHRLAER-REVEIA
MMAR_4157|M.marinum_M SGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP
MUL_4020|M.ulcerans_Agy99 SGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGR-RLIRFP
Mflv_3565|M.gilvum_PYR-GCK DGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR-RSLSLE
MAB_0055c|M.abscessus_ATCC_199 ADRLDLGIA--FAGPHPAGIDHCALFTETLRLVVGTGHRLAMRHRSLPVA
MLBr_02041|M.leprae_Br4923 EGALDAAMIALPVET--AGIAEIPIYDEDFVLALPPGHPLSGK-RRVPTT
MAV_2838|M.avium_104 EGALDAALIALPAET--AGVTAIPIYDEDFVLALPPGHPLAGK-RRVPAT
Mb2303c|M.bovis_AF2122/97 DGIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKWARRSRVVSAR
Rv2282c|M.tuberculosis_H37Rv DGIADLGFIENPCPP--TGLGSVVVARDELVVVVPPGHKWARRSRVVSAR
TH_3504|M.thermoresistible__bu DGTVQLGLRRGVVPT--PELATAVIGYHRVRVAFVDSHPLAAR-ESVDIT
. : .: : . .* : : . :
MSMEG_1678|M.smegmatis_MC2_155 ELAEEPMVLLDLPD---SRDYFESMLAK---AGVTPRIR-YRSASYEAVR
Mvan_4518|M.vanbaalenii_PYR-1 ELLDDPIVCAPLTAG-TWRDYWLAMDVR---GNRPPTIA-AVAATYEAET
MMAR_4157|M.marinum_M ELAAYPFVVLDRDH--TLRRIVDAACAR---HGIDPTLA-FEGTDVGTLR
MUL_4020|M.ulcerans_Agy99 ELAAYPFVVLDRDH--TLRRIVDAACAR---HGIDPTPA-FEGTDVGTLR
Mflv_3565|M.gilvum_PYR-GCK QLSRHPLISLPAGT--GLRTRLDTACAA---AGLRPRIA-FEATSPAELA
MAB_0055c|M.abscessus_ATCC_199 QLSREALGLLSPDF--ATRQDIDAYFAG---LGVAPHIA-VEANSISALL
MLBr_02041|M.leprae_Br4923 ALAQLPLLLLDEGH--CLRDQTLDICRK---SGVQAELANTRAASLATAV
MAV_2838|M.avium_104 ALADLPLLLLDEGH--CLRDQALDVCHK---AGVRAELANTRAASLATAV
Mb2303c|M.bovis_AF2122/97 ELAQTPLVTREPNS--GIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVR
Rv2282c|M.tuberculosis_H37Rv ELAQTPLVTREPNS--GIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVR
TH_3504|M.thermoresistible__bu ELAREQVALWAPPGTSYYSDFLMGACRR---AGFEPDYVVSRVQGAATVA
* . .
MSMEG_1678|M.smegmatis_MC2_155 GLVARGHGFSILNQIPAHRGTYDGGEVSVVPIRDELPGLPIVLARLRSVR
Mvan_4518|M.vanbaalenii_PYR-1 TAIARGLGISFTTSSVAR--FYDRPGIVYVPICDRPPSHTALAWNPADLT
MMAR_4157|M.marinum_M GLIGANLGVGVLPQATAR-----PADIIEIAIDDAQLVRPIAIGWIADRC
MUL_4020|M.ulcerans_Agy99 GLIGANLGVGVLPQATAR-----PADIIEIAIDDAQLVRPIAIGWIADRC
Mflv_3565|M.gilvum_PYR-GCK ELARHGLGVAILPQSMAR----GGSGLHALRLAPELRGRLVWAWRADGAN
MAB_0055c|M.abscessus_ATCC_199 EFVKRGSLATVLPDAIAH----EHSDLHLVPLSPPLPIRTVELLRRSSAY
MLBr_02041|M.leprae_Br4923 QCVTGGLGVTLLPQSAAP-VESVRSKLGLAQFAAPCPGRRIGLAFRSASG
MAV_2838|M.avium_104 QCVTGGLGVTLIPQSAVP-VEASRSRLGLAQFAAPRPGRRIGLVFRSSSG
Mb2303c|M.bovis_AF2122/97 AAVLAGAGPAAMSRLAIA-DDLAFGRLLAVDIPALNLRRQLRAIWVGGRT
Rv2282c|M.tuberculosis_H37Rv AAVLAGAGPAAMSRLAIA-DDLAFGRLLAVDIPALNLRRQLRAIWVGGRT
TH_3504|M.thermoresistible__bu APLTTG-GIAFVTAAAGP---TMNGRVQVVDLTPPLLVPVQALWQR----
. : :
MSMEG_1678|M.smegmatis_MC2_155 STARARAVADAAREIFADRPGRRAGPT-
Mvan_4518|M.vanbaalenii_PYR-1 PQADALVRHVQSQWSFGDGDNADHG---
MMAR_4157|M.marinum_M LPSSAVAFRETALGCYGHRVSAAGV---
MUL_4020|M.ulcerans_Agy99 LPSSAVAFRETAFGCYGHRDSAAGV---
Mflv_3565|M.gilvum_PYR-GCK PAARVLGERARAMAVSPGSGAPAVVPGA
MAB_0055c|M.abscessus_ATCC_199 HSA-----AARAFTEMVHAGARGR----
MLBr_02041|M.leprae_Br4923 RSASYRQIAKIIGELISTEHHVRLVA--
MAV_2838|M.avium_104 RDDSYRELAGLIGELISSQHQVRLVK--
Mb2303c|M.bovis_AF2122/97 PPAG------AIRDLLSHITSRST----
Rv2282c|M.tuberculosis_H37Rv PPAG------AIRDLLSHITSRST----
TH_3504|M.thermoresistible__bu ----------HTLSAIRDRILEGLG---