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TLRQLRYFAVLGHELNYRRAAEKLFITQPALSTAIKQLEHQFGVVLFHRNTREVALTDLGAAWLPQVQQA LSGVDAVVDNLIMLSGTRRGVLRVGYLIGTGADLLFRLVRHFEAAYPDVTVEPIEFDFADPTAGLADGTT EVAIIRPPVDLPEHRMLILDSESWVACLPRDHRLAERREVEIAELLDDPIVCAPLTAGTWRDYWLAMDVR GNRPPTIAAVAATYEAETTAIARGLGISFTTSSVARFYDRPGIVYVPICDRPPSHTALAWNPADLTPQAD ALVRHVQSQWSFGDGDNADHG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4518 | - | - | 100% (302) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 3e-24 | 28.33% (300) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0328 | - | 7e-22 | 30.17% (295) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 2e-09 | 33.33% (126) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_1346 | - | 7e-28 | 31.94% (288) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 2e-09 | 33.33% (126) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02041 | oxyR | 7e-15 | 26.02% (246) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 1e-24 | 29.15% (271) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 3e-16 | 28.74% (254) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2789 | - | 2e-16 | 31.29% (278) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_1909 | - | 3e-29 | 33.68% (291) | putative HTH-type transcriptional regulator YnfL |
| M. thermoresistible (build 8) | TH_3504 | - | 3e-14 | 23.67% (245) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 5e-16 | 30.93% (194) | LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4157|M.marinum_M ----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSR
MUL_4020|M.ulcerans_Agy99 ----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVSR
Mb0121|M.bovis_AF2122/97 ----------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSS
Rv0117|M.tuberculosis_H37Rv ----------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALSS
MAB_2238|M.abscessus_ATCC_1997 ----------------MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSA
Mflv_1346|M.gilvum_PYR-GCK ----------------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQ
MSMEG_1909|M.smegmatis_MC2_155 ----------------MELRHLRYFAAVADTCHFGQAAEQLHVAQPALSY
Mvan_4518|M.vanbaalenii_PYR-1 ----------------MTLRQLRYFAVLGHELNYRRAAEKLFITQPALST
TH_3504|M.thermoresistible__bu -----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSS
MLBr_02041|M.leprae_Br4923 ---------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQ
MAV_2789|M.avium_104 MKDLCSSGMDVVQAGRVELRHLRAFEAVARLESFTLAAQELSITQPALSR
: * : .: *: : * :*
MMAR_4157|M.marinum_M AITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRE
MUL_4020|M.ulcerans_Agy99 AITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVRE
Mb0121|M.bovis_AF2122/97 AIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDA
Rv0117|M.tuberculosis_H37Rv AIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVDA
MAB_2238|M.abscessus_ATCC_1997 QIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVREAADE
Mflv_1346|M.gilvum_PYR-GCK QIRQLEREVGADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARR
MSMEG_1909|M.smegmatis_MC2_155 AIRQLETELDVTLFYRTTRQVSLTPAGEFLRAEAARILAGVDDAERGVRR
Mvan_4518|M.vanbaalenii_PYR-1 AIKQLEHQFGVVLFHRNTREVALTDLGAAWLPQVQQALSGVDAVVDNLIM
TH_3504|M.thermoresistible__bu AVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQ
MLBr_02041|M.leprae_Br4923 ALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAG
MAV_2789|M.avium_104 TIKQLEDALEASLLDRTSRHVATTPAGRVFLGHVERILTELGRGVDAVRQ
: ** . *: * . *
MMAR_4157|M.marinum_M LAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQRSGQGVLS
MUL_4020|M.ulcerans_Agy99 LAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQRSGQGVLS
Mb0121|M.bovis_AF2122/97 VRSGITGTLRLGTVPTASTTAS-LVLSAFCSAHPLAKVQVCSRLAATELY
Rv0117|M.tuberculosis_H37Rv VRSGITGTLRLGTVPTASTTAS-LVLSAFCSAHPLAKVQVCSRLAATELY
MAB_2238|M.abscessus_ATCC_1997 IGGLIRGHIAFGTVTSHGADLS-SLLSAFHRDHPAISITLT-EAGCEELV
Mflv_1346|M.gilvum_PYR-GCK IGTGAEGRLVVGCVGSATYSLLPRLVRELRAALPAVDLRVRGEMLAPEQL
MSMEG_1909|M.smegmatis_MC2_155 IARGRGGLLRLGLTGTAAFSHLPRIARIVKREMPDVALEIHADMLTPVQC
Mvan_4518|M.vanbaalenii_PYR-1 LSGTRRGVLRVGYLIGTGADLLFRLVRHFEAAYPDVTVEPIEFDFADPTA
TH_3504|M.thermoresistible__bu TEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLR-QLYPDALT
MLBr_02041|M.leprae_Br4923 ESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVV-EDQTEHLL
MAV_2789|M.avium_104 QAS-----IRLGFSWLLPDPWAQDTVARFERTTRTTVSLIR----TDDAL
.*
MMAR_4157|M.marinum_M DLVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRLIR
MUL_4020|M.ulcerans_Agy99 DLVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRLIR
Mb0121|M.bovis_AF2122/97 RRLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTSTLV
Rv0117|M.tuberculosis_H37Rv RRLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTSTLV
MAB_2238|M.abscessus_ATCC_1997 AGLREGRLDGAIVALGAQRLAGLGLQVIDDQPLVAAVAADDLLATRRTIT
Mflv_1346|M.gilvum_PYR-GCK AALHAKDIDLALMRPPVDD-PALTAVSLRRDRLLVALPAGHRCADRDEVS
MSMEG_1909|M.smegmatis_MC2_155 DSLRSGALDLGVLRPPAVG-DGVELTVIDAESLVLAVSADHRLAAEPVVS
Mvan_4518|M.vanbaalenii_PYR-1 G-LADGTTEVAIIRP-PVDLPEHRMLILDSESWVACLPRDHRLAERREVE
TH_3504|M.thermoresistible__bu DAVFDGTVQLG-LRRGVVPTPELATAVIGYHRVRVAFVDSHPLAARESVD
MLBr_02041|M.leprae_Br4923 TALREGALDAAMIALPVET-AGIAEIPIYDEDFVLALPPGHPLSGKRRVP
MAV_2789|M.avium_104 GAVQQGRVDIALVRGHVTS-TAVRIVHLFDEPRVAVCSVHSPLAKRAKLD
: . : . . :
MMAR_4157|M.marinum_M FPELAAYPFVVLDRDHT--LRRIVDAACARHGIDPTLAFEGTD-VGTLRG
MUL_4020|M.ulcerans_Agy99 FPELAAYPFVVLDRDHT--LRRIVDAACARHGIDPTPAFEGTD-VGTLRG
Mb0121|M.bovis_AF2122/97 WRDAAQLPLALLTADMR--DRQVIDAAFADHAVSAIPQVETDS-VASLFA
Rv0117|M.tuberculosis_H37Rv WRDAAQLPLALLTADMR--DRQVIDAAFADHAVSAIPQVETDS-VASLFA
MAB_2238|M.abscessus_ATCC_1997 LQRLCEHTLICLPTGSG--VRSILESECRSLGLSPNVAFEASS-PRALVS
Mflv_1346|M.gilvum_PYR-GCK LADLRDEDFISHAGGGRSRMSALLAALCADAGFSPRIRDEVDE-TSTLVT
MSMEG_1909|M.smegmatis_MC2_155 MADLRAEPFVGYASRDSAVNDAVLRS-CRSAGFVPDRAHTAPG-TAVLLA
Mvan_4518|M.vanbaalenii_PYR-1 IAELLDDPIVCAPLTAG-TWRDYWLAMDVRGNRPPTIAAVAAT-YEAETT
TH_3504|M.thermoresistible__bu ITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQ-GAATVA
MLBr_02041|M.leprae_Br4923 TTALAQLPLLLLDEGHC--LRDQTLDICRKSGVQAELANTRAASLATAVQ
MAV_2789|M.avium_104 WAEVPRWPLVINTASGT------TGPWSWPAGDGPETIVETTN-FDEWIE
. .
MMAR_4157|M.marinum_M LIGANLGVGVLPQATARPADIIEIAIDDAQLVRPIAIGWIADRCLPSSAV
MUL_4020|M.ulcerans_Agy99 LIGANLGVGVLPQATARPADIIEIAIDDAQLVRPIAIGWIADRCLPSSAV
Mb0121|M.bovis_AF2122/97 QVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNAL
Rv0117|M.tuberculosis_H37Rv QVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNAL
MAB_2238|M.abscessus_ATCC_1997 LVEQGLGIAVVPAPYVRNR--AGVLALDIR------PALRGRLALAWRLD
Mflv_1346|M.gilvum_PYR-GCK LVAGGLGVALVPEP-TAALEIGGVTYRPLAAKAGATIELLAVYR-SAD--
MSMEG_1909|M.smegmatis_MC2_155 LVAADLGVAVVPES-VRALPLDGVVFRDLLD--GGTVELALAWRRAADRD
Mvan_4518|M.vanbaalenii_PYR-1 AIARGLGISFTTSSVARFYDRPGIVYVPICDRPPSHTALAWNPADLTPQA
TH_3504|M.thermoresistible__bu APLTTGGIAFVTAAAGPTMN-GRVQVVDLTPPLLVPVQALWQRHTLSAIR
MLBr_02041|M.leprae_Br4923 CVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRS
MAV_2789|M.avium_104 SVAADRGIGVIPDVAIRRNVHPGVRFVALRDAPDIPVALAFVKRASGPVL
. .
MMAR_4157|M.marinum_M AFRETALGCYGHRVSAAGV---------------
MUL_4020|M.ulcerans_Agy99 AFRETAFGCYGHRDSAAGV---------------
Mb0121|M.bovis_AF2122/97 GPGSPVARALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv GPGSPVARALITCAQALALNEFFDTQLRGITRRR
MAB_2238|M.abscessus_ATCC_1997 GPVGPAARAFLERARAVL----------------
Mflv_1346|M.gilvum_PYR-GCK --ASPLTAKVVDVLRATV----------------
MSMEG_1909|M.smegmatis_MC2_155 SHANPLVGSVVDILAPAPSRESVPSLEERL----
Mvan_4518|M.vanbaalenii_PYR-1 DALVRHVQSQWSFGDGDNADHG------------
TH_3504|M.thermoresistible__bu DRILEGLG--------------------------
MLBr_02041|M.leprae_Br4923 ASYRQIAKIIGELISTEHHVRLVA----------
MAV_2789|M.avium_104 RRFIEAAVDAAANQ--------------------