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MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRCFAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFE AVCDDVYGKILTRVMLAVSGSHSVVGLLRAVLTESMRINHESPELAGFVATAPIDARRHRELAESFATQG ARMADALTDAVRSGQDAGDIAADLDPVRVARLISAVVDGFAHAAVSADPDEMDNMNELFQSLLLDTT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1565 | - | - | 100% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0092 | - | 3e-16 | 26.24% (202) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3177 | - | 6e-15 | 28.25% (177) | transcriptional regulatory protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 2e-18 | 26.09% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0744 | - | 6e-17 | 27.47% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 2e-18 | 26.09% (207) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 9e-07 | 41.54% (65) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0647 | - | 5e-11 | 29.34% (167) | transcriptional regulator TetR |
| M. marinum M | MMAR_0237 | - | 1e-18 | 29.78% (178) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 4e-16 | 28.65% (171) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0251 | - | 3e-11 | 25.00% (184) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_4876 | - | 1e-21 | 31.05% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2776 | - | 3e-18 | 33.70% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MAV_5151|M.avium_104 --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2776|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0237|M.marinum_M --------------------------------------------------
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00316|M.leprae_Br4923 --------------------------------------------------
MAB_0647|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1565|M.smegmatis_MC2_155 --------------------------------------------------
TH_0251|M.thermoresistible__bu --------------------------------------------------
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
Mflv_0744|M.gilvum_PYR-GCK -----------MWHN--FNVPYTASRGPGRPPAAKAAETRERILRAAREV
Mvan_2776|M.vanbaalenii_PYR-1 ---------------------MPAVRRPGRPVGANSDQTRRTILCAARDV
MMAR_0237|M.marinum_M -------------------------------MGARGEQTRQRIITAAMRC
MUL_4876|M.ulcerans_Agy99 ----------------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRC
MLBr_00316|M.leprae_Br4923 -------------MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEA
MAB_0647|M.abscessus_ATCC_1997 ------------------------MDQPARPLRADAARNRARVLEVAYQT
MSMEG_1565|M.smegmatis_MC2_155 -----------------MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRC
TH_0251|M.thermoresistible__bu ------------------------------VTDDHLAARRRQILDGARRC
* :: *
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
Mflv_0744|M.gilvum_PYR-GCK FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
Mvan_2776|M.vanbaalenii_PYR-1 IAEHGYRAATFQQIALRAGVSRPTLHYYFATREQLYEVLLADVRAEVARC
MMAR_0237|M.marinum_M VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPR
MUL_4876|M.ulcerans_Agy99 VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPR
MLBr_00316|M.leprae_Br4923 FATEGLS-VPIDEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDD
MAB_0647|M.abscessus_ATCC_1997 FAEEGLG-VPIDEIARRAGVGAGTVYRHFPAKEDLYRAIAEDRMGSVIDK
MSMEG_1565|M.smegmatis_MC2_155 FAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAVCDDVYGKILTR
TH_0251|M.thermoresistible__bu FAEYGYEQATVRRLEQATGLSRGAIFHHFKDKDTLFFELAREDAERMAEV
.: * .. : :.: :: :* : * : :
Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MAV_5151|M.avium_104 GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN
Mflv_0744|M.gilvum_PYR-GCK AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI
Mvan_2776|M.vanbaalenii_PYR-1 AAEATLAG-SLLRQLEVFIAEMHRLGGAEPALMGLVVTARVD-HRGVLRH
MMAR_0237|M.marinum_M LHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGG
MUL_4876|M.ulcerans_Agy99 LHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGG
MLBr_00316|M.leprae_Br4923 GYVLLKSAGPGEALFTYLRSLVLHWGATDRG-----LVDALAGAGGIDIL
MAB_0647|M.abscessus_ATCC_1997 GRELLAAVDPGEALFEFLRS-MMDWGGTDQG-----LVDALSGAG-IDVQ
MSMEG_1565|M.smegmatis_MC2_155 VMLAVSGSHSVVGLLRAVLTESMRINHESPELAGFVATAPIDARRHRELA
TH_0251|M.thermoresistible__bu AS-----REGLIQVMRDLIAAPEQYDWLTTR-----LEIARKLRNDPEFH
: .
Mb0149|M.bovis_AF2122/97 RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
Rv0144|M.tuberculosis_H37Rv RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
MAV_5151|M.avium_104 TAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLY
Mflv_0744|M.gilvum_PYR-GCK NDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFY
Mvan_2776|M.vanbaalenii_PYR-1 EAATAVVATVHAFFDAVVVDAVRRGELAFDTDAHAVADLLGALFWGLVFH
MMAR_0237|M.marinum_M RRTYPGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQ
MUL_4876|M.ulcerans_Agy99 RRTYPGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQ
MLBr_00316|M.leprae_Br4923 GVAPDAEDAFLTILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAYN
MAB_0647|M.abscessus_ATCC_1997 ALIPHIEESFYAVLGDLLRAAQQAGTVRSDVGVHEVKALLVGCQAMQSYN
MSMEG_1565|M.smegmatis_MC2_155 ESFATQGARMADALTDAVRSGQDAGDIAADLDPVRVARLISAVVDGFAHA
TH_0251|M.thermoresistible__bu RGWSELSAELAAATTARLRRQKQAGRLRDDVPGEVLRTYLELVLDGLVAR
: * . :
Mb0149|M.bovis_AF2122/97 IGFVGSYQRMATITDSFQQLLAGTLWRPPT-------
Rv0144|M.tuberculosis_H37Rv IGFVGSYQRMATITDSFQQLLAGTLWRPPT-------
MAV_5151|M.avium_104 AGYVETYQEMLAVTGMLRQLLEGALWRPGS-------
Mflv_0744|M.gilvum_PYR-GCK AGFVGDRSDLSAVVHKLELLLAGKLWNVAD-------
Mvan_2776|M.vanbaalenii_PYR-1 AGFISGADGAPEIARQLLRMVGFGLLDTPEPASVDA-
MMAR_0237|M.marinum_M AANLGP-QSYDVTLDSAKQLLRGSLFAGAKPTATHRT
MUL_4876|M.ulcerans_Agy99 AANLGP-QSYDVTLDSAKQLLRGSLFAGAKPTATRRT
MLBr_00316|M.leprae_Br4923 S----------ALAERVTDVVVDGLRAAR--------
MAB_0647|M.abscessus_ATCC_1997 K----------DVSRQVTDVVFDGLRPRP--------
MSMEG_1565|M.smegmatis_MC2_155 AVSADP-----DEMDNMNELFQSLLLDTT--------
TH_0251|M.thermoresistible__bu LASGDD----PEKLSAVLDLVEASVRHQGSE------
:. :