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M. thermoresistible (build 8) TH_0251 ()

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
coordinates: 552179 - 552742
length: 188

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0251-100% (188)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. thermoresistible (build 8)TH_4497-1e-0725.90% (166) PUTATIVE putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_4573-3e-0737.10% (62) PUTATIVE putative transcriptional regulator, TetR family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1510c-3e-8381.32% (182) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3666-3e-9089.56% (182) TetR family transcriptional regulator
M. tuberculosis H37RvRv1474c-3e-8381.32% (182) transcriptional regulatory protein
M. leprae Br4923MLBr_01070-2e-0624.40% (168) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_2731-3e-7877.47% (182) TetR family transcriptional regulator
M. marinum MMMAR_2281-1e-8381.87% (182) transcriptional regulatory protein
M. avium 104MAV_3305-2e-8380.65% (186) HTH-type transcriptional repressor AcnR
M. smegmatis MC2 155MSMEG_3142-1e-8886.96% (184) HTH-type transcriptional repressor AcnR
M. ulcerans Agy99MUL_1483-4e-8482.42% (182) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2744-4e-9087.50% (184) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_0251|M.thermoresistible__bu      --------------------VTDDHLAARRRQILDGARRCFAEYGYEQAT
MSMEG_3142|M.smegmatis_MC2_155      -----------------MPRVTDDHLAARRRQILDGARRCFAKYGYESAT
Mflv_3666|M.gilvum_PYR-GCK          -----------------MPRVTDDHLAARRRQILDGARRCFAEYGYESAT
Mvan_2744|M.vanbaalenii_PYR-1       -----------------MPRVTDDHLAARRRQILDGARRCFAEYGYDRAT
Mb1510c|M.bovis_AF2122/97           -----------------MPKVSEDHLAARRRQILDGARRCFAEYGYDKAT
Rv1474c|M.tuberculosis_H37Rv        -----------------MPKVSEDHLAARRRQILDGARRCFAEYGYDKAT
MMAR_2281|M.marinum_M               -----------------MPKVSEDHLAARRRQILDGARRCFAEYGYDKAT
MUL_1483|M.ulcerans_Agy99           -----------------MPKVSEDHLAARRRQILDGARRCFAEYGYDKAT
MAV_3305|M.avium_104                -----------------MPKVSEDHLAARRRQILDGARRCFAEFGYDKAT
MAB_2731|M.abscessus_ATCC_1997      -----------------MPRVSEDHLAARRRQILDGARRCFAEYGYDGAT
MLBr_01070|M.leprae_Br4923          MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
                                                         ::     *.: **  *.* :*:      :

TH_0251|M.thermoresistible__bu      VRRLEQATGLSRGAIFHHFKDKDTLFFELAREDAER----MAEVASREGL
MSMEG_3142|M.smegmatis_MC2_155      VRRLEETIGLSRGAIFHHFKDKDTLFFELAREDAER----MAEVAAREGL
Mflv_3666|M.gilvum_PYR-GCK          VRRLEQTIGLSRGAIFHHFRDKDTLFFELAREDAER----MADVAAREGL
Mvan_2744|M.vanbaalenii_PYR-1       VRRLEQTIGLSRGAIFHHFRDKDTLFFELAREDAER----MADVAAREGL
Mb1510c|M.bovis_AF2122/97           VRRLEQAIGMSRGAIFHHFRDKDALFFALAREDTER----MAAVASREGL
Rv1474c|M.tuberculosis_H37Rv        VRRLEQAIGMSRGAIFHHFRDKDALFFALAREDTER----MAAVASREGL
MMAR_2281|M.marinum_M               VRRLEQAIGMSRGAIFHHFRDKDALFFALAHEDAER----MADVASREGL
MUL_1483|M.ulcerans_Agy99           VRRLEQAIGMSRGAIFHHFRDKDALFFALAHEDAER----MADVASREGL
MAV_3305|M.avium_104                VRRLEQAIGMSRGAIFHHFRDKDALFFALAHEDAER----MAEVASRAGL
MAB_2731|M.abscessus_ATCC_1997      VRRLEHTIGMSRGAIFHHFRDKDTLFFALAREDAER----MANVASREGL
MLBr_01070|M.leprae_Br4923          VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
                                    * .* .  *:** :::.:* .*::::: *  :   :    :  :* :   

TH_0251|M.thermoresistible__bu      IQVMRDLIAAPEQYDWLTTRLEIARK----LRNDPEFHRGWSELSAELAA
MSMEG_3142|M.smegmatis_MC2_155      IQVMRDLLAAPEQYDWLATRLEIARK----LRNDPDFHRGWAERSAELTA
Mflv_3666|M.gilvum_PYR-GCK          IQVMRDMLAAPDQFDWLATRLEIARK----LRNDPAFSQGWAERSAELSA
Mvan_2744|M.vanbaalenii_PYR-1       IQVMRDMLAAPDQFNWLATRLEIARK----LRNDPAFSRGWAERSAELSA
Mb1510c|M.bovis_AF2122/97           IGVMRDMLAAPDQFDWLATRLEIARK----LRNDPDFSRGWAERSAELAA
Rv1474c|M.tuberculosis_H37Rv        IGVMRDMLAAPDQFDWLATRLEIARK----LRNDPDFSRGWAERSAELAA
MMAR_2281|M.marinum_M               IQVMRDMLAAPDQFDWLATRLEIARK----LRNDPEFSRGWAERSAELAA
MUL_1483|M.ulcerans_Agy99           IQVMRDMLAAPEQFDWLATRLEIARK----LRNDPEFSRGWAERSAELAA
MAV_3305|M.avium_104                IQVMRDMLAAPDQFDWLATRLEIARK----LRNDPAFSRGWAERSAELAA
MAB_2731|M.abscessus_ATCC_1997      VQVMRDMLADPSQFDWLATRLEIARK----LRNDPEFRRGWNQRSEELNT
MLBr_01070|M.leprae_Br4923          DPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLWSTVMQQWID
                                      .     * .  ::   *:  :*        ..* . : *     :   

TH_0251|M.thermoresistible__bu      ATTARLRRQKQAGRLRDDVPGEVLRTYLELVLDGLVARLASGD-----DP
MSMEG_3142|M.smegmatis_MC2_155      ATTERLRRQKQAGRLRDDVPSAVLHIYLDVVLDGLVARLASGE-----DS
Mflv_3666|M.gilvum_PYR-GCK          ATTERLRRQKQAGRLRDDVDGEVLRTYLELVLDGLVARLASGD-----DP
Mvan_2744|M.vanbaalenii_PYR-1       ATTERLRRQKRAGRLRDDVPGDVLRTYLELVLDGLVARLASGD-----DP
Mb1510c|M.bovis_AF2122/97           ATTDRLRRQKQANRVRDDVPSDVLRCYLDLVLDGLLARLASGE-----DP
Rv1474c|M.tuberculosis_H37Rv        ATTDRLRRQKQANRVRDDVPSDVLRCYLDLVLDGLLARLASGE-----DP
MMAR_2281|M.marinum_M               ATTDRLRRQKQANRVRDDVPNEVLQCYLDLVLDGLVARLASGE-----DP
MUL_1483|M.ulcerans_Agy99           ATTDRLRRQKQANRVRDDVPNEVLQCYLDLVLDGLVARLASGE-----DP
MAV_3305|M.avium_104                ATTDRLRRQTEAHRVRDDVPGDVLQCYLELVLDGLVARLASGE-----DP
MAB_2731|M.abscessus_ATCC_1997      ATLARLQRQKKAGRLREDVPSEVILGYLDLVLDGLVARLAAGE-----ST
MLBr_01070|M.leprae_Br4923          YNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPDK
                                     .   :: : ..    : :    :   *::: : ::*   :.:     . 

TH_0251|M.thermoresistible__bu      EKLSAVLDLVEASVRHQGSE--------------
MSMEG_3142|M.smegmatis_MC2_155      KNLSAVLDLVEASVRQQPKPAPAVSTDHSFSDES
Mflv_3666|M.gilvum_PYR-GCK          EKLSAVLDLVEASVRQP-----------------
Mvan_2744|M.vanbaalenii_PYR-1       EKLGAVLDLVEASVRQQ-----------------
Mb1510c|M.bovis_AF2122/97           QRLAAVLDLVENSVRRS-----------------
Rv1474c|M.tuberculosis_H37Rv        QRLAAVLDLVENSVRRS-----------------
MMAR_2281|M.marinum_M               QRLTDVLDLVENSLRRS-----------------
MUL_1483|M.ulcerans_Agy99           QRLTDVLDLVENSLRRS-----------------
MAV_3305|M.avium_104                QRLSAVLDLVENSVRRNDSRPG------------
MAB_2731|M.abscessus_ATCC_1997      ESLSRVLDLVEDSVRRADHA--------------
MLBr_01070|M.leprae_Br4923          KVIDTLVHIWLASIYGS-----------------
                                    : :  ::.:   *: