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WHNFNVPYTASRGPGRPPAAKAAETRERILRAAREVFSELGYDAATFQAIAIRADLTRPAINHYFASKGV LWAEVVEQTNATIVSEAIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELINDEH DSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFYAGFVGDRSDLSAVVHKLELLLAGK LWNVAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0744 | - | - | 100% (217) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 4e-20 | 33.33% (195) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0297 | - | 4e-10 | 30.61% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 4e-62 | 55.14% (214) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 4e-62 | 55.14% (214) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 33.33% (78) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1149 | - | 6e-08 | 34.25% (73) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0355 | - | 3e-60 | 55.88% (204) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 3e-56 | 52.97% (202) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0092 | - | 5e-84 | 72.51% (211) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1278 | - | 2e-49 | 66.21% (145) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4765 | - | 2e-60 | 55.88% (204) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0103 | - | 2e-83 | 80.75% (187) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0744|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0103|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155 --------------------------------------------------
TH_1278|M.thermoresistible__bu --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M --------------------------------------------------
MUL_4765|M.ulcerans_Agy99 --------------------------------------------------
MAV_5151|M.avium_104 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 -------------------------------------------------M
MAB_1149|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK -------------MWHNFNVPYTASRGPGRPP--AAKAAETRERILRAAR
Mvan_0103|M.vanbaalenii_PYR-1 ---------------------------------------------MRAAR
MSMEG_0092|M.smegmatis_MC2_155 -------------------MAHIASRGPGRPP--AAKAAETRERILSAAR
TH_1278|M.thermoresistible__bu --------------------------------------------------
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPP--AAKADETRKRILHAAR
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPP--AAKADETRKRILHAAR
MMAR_0355|M.marinum_M -------------------MQLTASRGPGRPP--AAKADDTRRRIVGAAR
MUL_4765|M.ulcerans_Agy99 ------------------MMQLTASRGPGRPP--AAKADDTRRRIVGAAR
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPP--AAKADETRQRIIQAAR
MLBr_00815|M.leprae_Br4923 NNLAKAAQRRTVRPIDRGRLSDDIATPNQRSN--RLSRDKRRGQLLIVAS
MAB_1149|M.abscessus_ATCC_1997 ------------------MAVPSRPDVPGRTPRVRMAGSERRRQLIDVAR
Mflv_0744|M.gilvum_PYR-GCK EVFSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIV
Mvan_0103|M.vanbaalenii_PYR-1 EIFSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVV
MSMEG_0092|M.smegmatis_MC2_155 EVFSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVI
TH_1278|M.thermoresistible__bu -----------------------------------VLYQEVVQQTNSLVV
Mb0149|M.bovis_AF2122/97 QVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVI
Rv0144|M.tuberculosis_H37Rv QVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVI
MMAR_0355|M.marinum_M EVFSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVV
MUL_4765|M.ulcerans_Agy99 EVFSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVV
MAV_5151|M.avium_104 LVFSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVI
MLBr_00815|M.leprae_Br4923 DVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
MAB_1149|M.abscessus_ATCC_1997 SLFAERGYEATSIEEIAQRAGVSKPVVYEHFGGKEGLYAVVVDREMSVLL
*: *: . ::
Mflv_0744|M.gilvum_PYR-GCK SEAIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPE
Mvan_0103|M.vanbaalenii_PYR-1 GVGIARAHEQTSLLNRLMAFLSVATQVDTDDRSAAAFLVTSVLESQRHPE
MSMEG_0092|M.smegmatis_MC2_155 AAGVARAREATSLLGRLSAFFAAAMDAESADRSSAAFLVTSVLESQRHPD
TH_1278|M.thermoresistible__bu AEGMERAKRETTLLGRLSAFFTAAMQAESEDRSTAAFLVISVLESQRHPE
Mb0149|M.bovis_AF2122/97 VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
Rv0144|M.tuberculosis_H37Rv VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPE
MMAR_0355|M.marinum_M AAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPE
MUL_4765|M.ulcerans_Agy99 AAGVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPE
MAV_5151|M.avium_104 GVGIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPE
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFE--NDNITEPR
MAB_1149|M.abscessus_ATCC_1997 DGITSSLTSYRS-RVRLEQVALALLSYIEERTDGFRILIRDSPPGVSSGT
. :* . :: .
Mflv_0744|M.gilvum_PYR-GCK LINDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMG
Mvan_0103|M.vanbaalenii_PYR-1 LADDDHDSLTNSRAFVSWAVNDAVARGELSADTDVNHLVEMLVAVVWGMG
MSMEG_0092|M.smegmatis_MC2_155 LVSEEQDALLNSRKFVAWAVNDAIERGELTTDTDIPAIVEMLVAVMWGMG
TH_1278|M.thermoresistible__bu LTIDEFDALKNSRAFVTWAVNDAIERGELTTNTDVSKIVEMLVAVLWGMG
Mb0149|M.bovis_AF2122/97 LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
Rv0144|M.tuberculosis_H37Rv LSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVG
MMAR_0355|M.marinum_M LRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVG
MUL_4765|M.ulcerans_Agy99 LRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVG
MAV_5151|M.avium_104 WNTAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVG
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCAR---
MAB_1149|M.abscessus_ATCC_1997 YSSLLNDAVS----QVSSILAGDFQRRGLDAEMAPLYAQALVGQVSMTAQ
: : : :
Mflv_0744|M.gilvum_PYR-GCK FYAGFVGDRSDLSAVVHKLELLLAGKLWNVAD------
Mvan_0103|M.vanbaalenii_PYR-1 FYAGFVGDRSDFGAVMHKLELLLANKLWNLGE------
MSMEG_0092|M.smegmatis_MC2_155 FYAGYVGRSEELAAIVDKFEMLMANKLWQLRD------
TH_1278|M.thermoresistible__bu FYAGYVGRQEDLKTVVEQFELLLANKLWQLKS------
Mb0149|M.bovis_AF2122/97 FYIGFVGSYQRMATITDSFQQLLAGTLWRPPT------
Rv0144|M.tuberculosis_H37Rv FYIGFVGSYQRMATITDSFQQLLAGTLWRPPT------
MMAR_0355|M.marinum_M FYAGFVGSYRDMENILDTLCKMMAGTLWKPRS------
MUL_4765|M.ulcerans_Agy99 FYAGFVGSYRDMENILDTLCKMMAGTLWKPRS------
MAV_5151|M.avium_104 LYAGYVETYQEMLAVTGMLRQLLEGALWRPGS------
MLBr_00815|M.leprae_Br4923 YWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----
MAB_1149|M.abscessus_ATCC_1997 WWLDAREP-KKEVVAAHIVNLCWHGLKHLEADPQLHEE
: . . .