For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTEAGQPRPLRRAPGRPVGADSAQTRMHILRVGCELINERGFAALTFQGVAKRSGLSRPTLNYYFATRDE LFHALVHEGNAIVQECIAAAKQQEDPLERVCALLDAMADAWSADPCLCQFLVNARLEAGRNPALPNGIAT AIRDFLDDVVGDAIAGGALSAHTDPAPVAQLLHAMVWGVGLCLGYGGTSDPKLITKQLESAIAGGLLTES RQAS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_3177 | - | - | 100% (214) | transcriptional regulatory protein, putative |
M. smegmatis MC2 155 | MSMEG_0092 | - | 3e-27 | 37.70% (183) | transcriptional regulatory protein |
M. smegmatis MC2 155 | MSMEG_1565 | - | 7e-15 | 28.25% (177) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0149 | - | 1e-23 | 33.00% (200) | TetR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_0744 | - | 7e-32 | 40.00% (205) | TetR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0144 | - | 2e-23 | 33.00% (200) | TetR family transcriptional regulator |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4352c | - | 3e-08 | 26.75% (157) | TetR family transcriptional regulator |
M. marinum M | MMAR_0355 | - | 8e-24 | 33.50% (200) | TetR family transcriptional regulator |
M. avium 104 | MAV_5151 | - | 1e-22 | 32.20% (205) | transcriptional regulator, TetR family protein |
M. thermoresistible (build 8) | TH_3831 | - | 1e-29 | 34.39% (189) | PUTATIVE putative transcriptional regulator, TetR family |
M. ulcerans Agy99 | MUL_4765 | - | 5e-24 | 33.50% (200) | TetR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_2776 | - | 2e-29 | 39.05% (210) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV MMAR_0355|M.marinum_M -------------------------------------------------- MUL_4765|M.ulcerans_Agy99 -------------------------------------------------- MAV_5151|M.avium_104 -------------------------------------------------- Mflv_0744|M.gilvum_PYR-GCK -------------------------------------------------- TH_3831|M.thermoresistible__bu -------------------------------------------------- Mvan_2776|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_3177|M.smegmatis_MC2_155 -------------------------------------------------- MAB_4352c|M.abscessus_ATCC_199 -------------------------------------------------- Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV MMAR_0355|M.marinum_M -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV MUL_4765|M.ulcerans_Agy99 ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV Mflv_0744|M.gilvum_PYR-GCK -----------MWHN--FNVPYTASRGPGRPPAAKAAETRERILRAAREV TH_3831|M.thermoresistible__bu ----------------------------MRPARTASSDTRARILEAARRI Mvan_2776|M.vanbaalenii_PYR-1 ---------------------MPAVRRPGRPVGANSDQTRRTILCAARDV MSMEG_3177|M.smegmatis_MC2_155 --------------MTEAGQPRPLRRAPGRPVGADSAQTRMHILRVGCEL MAB_4352c|M.abscessus_ATCC_199 -------------------------MVPLR--QAQALATRQRLVDVATEL * : : ** :: .. : Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA MMAR_0355|M.marinum_M FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA MUL_4765|M.ulcerans_Agy99 FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV Mflv_0744|M.gilvum_PYR-GCK FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE TH_3831|M.thermoresistible__bu IVERGYPAATCQGIARAAGVSRPTLHYYFASREEIYDCLVEQS-RNLLAE Mvan_2776|M.vanbaalenii_PYR-1 IAEHGYRAATFQQIALRAGVSRPTLHYYFATREQLYEVLLADVRAEVARC MSMEG_3177|M.smegmatis_MC2_155 INERGFAALTFQGVAKRSGLSRPTLNYYFATRDELFHALVHEG-NAIVQE MAB_4352c|M.abscessus_ATCC_199 FALHGFTSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVAE : *: . * :: :.::* :: ::*:. : :. : Mb0149|M.bovis_AF2122/97 GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS Rv0144|M.tuberculosis_H37Rv GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS MMAR_0355|M.marinum_M GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR MUL_4765|M.ulcerans_Agy99 GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR MAV_5151|M.avium_104 GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN Mflv_0744|M.gilvum_PYR-GCK AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI TH_3831|M.thermoresistible__bu CAERAMRYDTLVERLTEFGLRLREVDSRDRSTIAFLISARLEGMRNRELG Mvan_2776|M.vanbaalenii_PYR-1 AAEATLAG-SLLRQLEVFIAEMHRLGGAEPALMGLVVTARVD-HRGVLRH MSMEG_3177|M.smegmatis_MC2_155 CIAAAKQQEDPLERVCALLDAMADAWSADPCLCQFLVNARLEAGRNPALP MAB_4352c|M.abscessus_ATCC_199 VNHSLTSIESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPMALGWSRWR :. . . :: Mb0149|M.bovis_AF2122/97 RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY Rv0144|M.tuberculosis_H37Rv RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY MMAR_0355|M.marinum_M RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY MUL_4765|M.ulcerans_Agy99 RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY MAV_5151|M.avium_104 TAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLY Mflv_0744|M.gilvum_PYR-GCK NDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFY TH_3831|M.thermoresistible__bu ---EDPAMALREFFTELLADAVAAGELPSDIDIESAVEVMYTVLWGLGFY Mvan_2776|M.vanbaalenii_PYR-1 EAATAVVATVHAFFDAVVVDAVRRGELAFDTDAHAVADLLGALFWGLVFH MSMEG_3177|M.smegmatis_MC2_155 ---NGIATAIRDFLDDVVGDAIAGGALSAHTDPAPVAQLLHAMVWGVGLC MAB_4352c|M.abscessus_ATCC_199 ALDGGRSLG---LIQDILEELYRRGELVEAVDPQMAAQLILGAINESGMY :. : : * : * .: : . : Mb0149|M.bovis_AF2122/97 IGFVGSYQRMATITDSFQQLLAGTLWRPPT------ Rv0144|M.tuberculosis_H37Rv IGFVGSYQRMATITDSFQQLLAGTLWRPPT------ MMAR_0355|M.marinum_M AGFVGSYRDMENILDTLCKMMAGTLWKPRS------ MUL_4765|M.ulcerans_Agy99 AGFVGSYRDMENILDTLCKMMAGTLWKPRS------ MAV_5151|M.avium_104 AGYVETYQEMLAVTGMLRQLLEGALWRPGS------ Mflv_0744|M.gilvum_PYR-GCK AGFVGDRSDLSAVVHKLELLLAGKLWNVAD------ TH_3831|M.thermoresistible__bu TGFVERSTDMLVLAEQLENLFASA------------ Mvan_2776|M.vanbaalenii_PYR-1 AGFISGADGAPEIARQLLRMVGFGLLDTPEPASVDA MSMEG_3177|M.smegmatis_MC2_155 LGYGG-TSDPKLITKQLESAIAGGLLTESRQAS--- MAB_4352c|M.abscessus_ATCC_199 A--AAAPSERSSRAAEQLTLLCRGLLSPRSG----- .