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M. smegmatis MC2 155 MSMEG_3177 (-)

annotation: transcriptional regulatory protein, putative
coordinates: 3252280 - 3252924
length: 214

MTEAGQPRPLRRAPGRPVGADSAQTRMHILRVGCELINERGFAALTFQGVAKRSGLSRPTLNYYFATRDE
LFHALVHEGNAIVQECIAAAKQQEDPLERVCALLDAMADAWSADPCLCQFLVNARLEAGRNPALPNGIAT
AIRDFLDDVVGDAIAGGALSAHTDPAPVAQLLHAMVWGVGLCLGYGGTSDPKLITKQLESAIAGGLLTES
RQAS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3177--100% (214)transcriptional regulatory protein, putative
M. smegmatis MC2 155MSMEG_0092-3e-2737.70% (183) transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_1565-7e-1528.25% (177) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0149-1e-2333.00% (200) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0744-7e-3240.00% (205) TetR family transcriptional regulator
M. tuberculosis H37RvRv0144-2e-2333.00% (200) TetR family transcriptional regulator
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4352c-3e-0826.75% (157) TetR family transcriptional regulator
M. marinum MMMAR_0355-8e-2433.50% (200) TetR family transcriptional regulator
M. avium 104MAV_5151-1e-2232.20% (205) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_3831-1e-2934.39% (189) PUTATIVE putative transcriptional regulator, TetR family
M. ulcerans Agy99MUL_4765-5e-2433.50% (200) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_2776-2e-2939.05% (210) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0149|M.bovis_AF2122/97            MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv         MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M               --------------------------------------------------
MUL_4765|M.ulcerans_Agy99           --------------------------------------------------
MAV_5151|M.avium_104                --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3831|M.thermoresistible__bu      --------------------------------------------------
Mvan_2776|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_3177|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4352c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb0149|M.bovis_AF2122/97            ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv         ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MMAR_0355|M.marinum_M               -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV
MUL_4765|M.ulcerans_Agy99           ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV
MAV_5151|M.avium_104                -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
Mflv_0744|M.gilvum_PYR-GCK          -----------MWHN--FNVPYTASRGPGRPPAAKAAETRERILRAAREV
TH_3831|M.thermoresistible__bu      ----------------------------MRPARTASSDTRARILEAARRI
Mvan_2776|M.vanbaalenii_PYR-1       ---------------------MPAVRRPGRPVGANSDQTRRTILCAARDV
MSMEG_3177|M.smegmatis_MC2_155      --------------MTEAGQPRPLRRAPGRPVGADSAQTRMHILRVGCEL
MAB_4352c|M.abscessus_ATCC_199      -------------------------MVPLR--QAQALATRQRLVDVATEL
                                                                 *   : :  **  :: ..  :

Mb0149|M.bovis_AF2122/97            FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv         FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MMAR_0355|M.marinum_M               FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MUL_4765|M.ulcerans_Agy99           FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MAV_5151|M.avium_104                FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
Mflv_0744|M.gilvum_PYR-GCK          FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
TH_3831|M.thermoresistible__bu      IVERGYPAATCQGIARAAGVSRPTLHYYFASREEIYDCLVEQS-RNLLAE
Mvan_2776|M.vanbaalenii_PYR-1       IAEHGYRAATFQQIALRAGVSRPTLHYYFATREQLYEVLLADVRAEVARC
MSMEG_3177|M.smegmatis_MC2_155      INERGFAALTFQGVAKRSGLSRPTLNYYFATRDELFHALVHEG-NAIVQE
MAB_4352c|M.abscessus_ATCC_199      FALHGFTSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVAE
                                    :   *: . *   ::  :.::* :: ::*:.   :   :.      :   

Mb0149|M.bovis_AF2122/97            GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
Rv0144|M.tuberculosis_H37Rv         GIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELS
MMAR_0355|M.marinum_M               GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MUL_4765|M.ulcerans_Agy99           GVERARSVQTLLGQLCTFVMVAKEADASHPATTAFLATAVLESQRHPELR
MAV_5151|M.avium_104                GIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWN
Mflv_0744|M.gilvum_PYR-GCK          AIARAHEHTSLIERLSAFLTVATQAESDDRSAAAFLVTSVLESQRHPELI
TH_3831|M.thermoresistible__bu      CAERAMRYDTLVERLTEFGLRLREVDSRDRSTIAFLISARLEGMRNRELG
Mvan_2776|M.vanbaalenii_PYR-1       AAEATLAG-SLLRQLEVFIAEMHRLGGAEPALMGLVVTARVD-HRGVLRH
MSMEG_3177|M.smegmatis_MC2_155      CIAAAKQQEDPLERVCALLDAMADAWSADPCLCQFLVNARLEAGRNPALP
MAB_4352c|M.abscessus_ATCC_199      VNHSLTSIESPAERFLAIGSAVLDVLAREPIVQRIVFVEAPMALGWSRWR
                                                 :.  .        .       ::              

Mb0149|M.bovis_AF2122/97            RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
Rv0144|M.tuberculosis_H37Rv         RTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFY
MMAR_0355|M.marinum_M               RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MUL_4765|M.ulcerans_Agy99           RSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGVGFY
MAV_5151|M.avium_104                TAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLY
Mflv_0744|M.gilvum_PYR-GCK          NDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGMGFY
TH_3831|M.thermoresistible__bu      ---EDPAMALREFFTELLADAVAAGELPSDIDIESAVEVMYTVLWGLGFY
Mvan_2776|M.vanbaalenii_PYR-1       EAATAVVATVHAFFDAVVVDAVRRGELAFDTDAHAVADLLGALFWGLVFH
MSMEG_3177|M.smegmatis_MC2_155      ---NGIATAIRDFLDDVVGDAIAGGALSAHTDPAPVAQLLHAMVWGVGLC
MAB_4352c|M.abscessus_ATCC_199      ALDGGRSLG---LIQDILEELYRRGELVEAVDPQMAAQLILGAINESGMY
                                                :.   : :    * :    *    .: :   .    : 

Mb0149|M.bovis_AF2122/97            IGFVGSYQRMATITDSFQQLLAGTLWRPPT------
Rv0144|M.tuberculosis_H37Rv         IGFVGSYQRMATITDSFQQLLAGTLWRPPT------
MMAR_0355|M.marinum_M               AGFVGSYRDMENILDTLCKMMAGTLWKPRS------
MUL_4765|M.ulcerans_Agy99           AGFVGSYRDMENILDTLCKMMAGTLWKPRS------
MAV_5151|M.avium_104                AGYVETYQEMLAVTGMLRQLLEGALWRPGS------
Mflv_0744|M.gilvum_PYR-GCK          AGFVGDRSDLSAVVHKLELLLAGKLWNVAD------
TH_3831|M.thermoresistible__bu      TGFVERSTDMLVLAEQLENLFASA------------
Mvan_2776|M.vanbaalenii_PYR-1       AGFISGADGAPEIARQLLRMVGFGLLDTPEPASVDA
MSMEG_3177|M.smegmatis_MC2_155      LGYGG-TSDPKLITKQLESAIAGGLLTESRQAS---
MAB_4352c|M.abscessus_ATCC_199      A--AAAPSERSSRAAEQLTLLCRGLLSPRSG-----
                                                        .