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GARGEQTRQRIITAAMRCVAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPRLH AAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPGSKALRDVITEIVDDAR GRGVLSAGIAPGAAVDAICALTRGLTEQAANLGPQSYDVTLDSAKQLLRGSLFAGAKPTATHRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0237 | - | - | 100% (205) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0238 | - | 1e-44 | 48.99% (198) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0355 | - | 1e-12 | 25.91% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 3e-15 | 27.98% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 1e-13 | 29.44% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 3e-15 | 27.98% (193) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 3e-06 | 31.52% (92) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3372 | - | 4e-09 | 37.00% (100) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 5e-11 | 25.91% (193) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 1e-18 | 29.78% (178) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4573 | - | 7e-09 | 22.70% (163) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4876 | - | 1e-111 | 99.51% (205) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4204 | - | 1e-10 | 28.07% (171) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0237|M.marinum_M --------------------------------------------------
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MAV_5151|M.avium_104 --------------------------------------------------
Mflv_3637|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1565|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3372|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4573|M.thermoresistible__bu --------------------------------------------------
MLBr_02677|M.leprae_Br4923 --------------------------------------------------
Mvan_4204|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0237|M.marinum_M -------------------------------MGARGEQTRQRIITAAMRC
MUL_4876|M.ulcerans_Agy99 ----------------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRC
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
Mflv_3637|M.gilvum_PYR-GCK --------------MENETLSVSAGRKRGRPVAADSEQTRRTVLAAARDI
MSMEG_1565|M.smegmatis_MC2_155 -----------------MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRC
MAB_3372|M.abscessus_ATCC_1997 -------MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHV
TH_4573|M.thermoresistible__bu ---------------------MATQRATADVEEQHESDRRDQILEAANAC
MLBr_02677|M.leprae_Br4923 ------------------------MESQRRTQEERSTATRDALTLARHRL
Mvan_4204|M.vanbaalenii_PYR-1 -----------MSAPESAASDLGNAKRPYATLFAKGEDRRQRILAVAERL
* : .
MMAR_0237|M.marinum_M VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPR
MUL_4876|M.ulcerans_Agy99 VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEIEEIVLPR
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
Mflv_3637|M.gilvum_PYR-GCK IAERGYQATTFQQIAQRAGVSRPTLHYYFATREDLYDALLADVCER-LGR
MSMEG_1565|M.smegmatis_MC2_155 FAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAVCDDVYGKILTR
MAB_3372|M.abscessus_ATCC_1997 FADFGYAAGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFAL
TH_4573|M.thermoresistible__bu FAQLGIHRTSVQDVARAANVSRGTVYRYFEDRTILIEAAIEYGAQKFYQE
MLBr_02677|M.leprae_Br4923 WRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQ
Mvan_4204|M.vanbaalenii_PYR-1 LARNGWRSTSLAQIAREAGVTPAGLLHHFESKEQLLNAVLDARDAD--DD
* :* * : : * : :
MMAR_0237|M.marinum_M LHAAAAS--SDDIVDRLDAVLDESKRLMRD----------YPYLAGFLRA
MUL_4876|M.ulcerans_Agy99 LHAAAAS--SDDIVDRLDAVLDESKRLMRD----------YPYLAGFLRA
Mb0149|M.bovis_AF2122/97 GIERARR--EPTLMGRLAVVVDFAMEADAQ----------YPASTAFLAT
Rv0144|M.tuberculosis_H37Rv GIERARR--EPTLMGRLAVVVDFAMEADAQ----------YPASTAFLAT
MAV_5151|M.avium_104 GIKEADR--ETTLVGRLTAFISAAVKANAE----------NPAGSAFIIG
Mflv_3637|M.gilvum_PYR-GCK CAAAAAG--QDSLRGQLAAFMAEMNRLAVA----------EPAMMKLVVT
MSMEG_1565|M.smegmatis_MC2_155 VMLAVSG--SHSVVGLLRAVLTESMRINHE----------SPELAGFVAT
MAB_3372|M.abscessus_ATCC_1997 IHQHLAAGLPDTIEDTVRVFVGSAIANHRD----------SPRLHRVLFE
TH_4573|M.thermoresistible__bu IAAAMAK--KSTLAEQLGAMAETHAKILLD----------HRTRNRLMTD
MLBr_02677|M.leprae_Br4923 IASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAF
Mvan_4204|M.vanbaalenii_PYR-1 AHADRSG-------DLIAELTRVPKRFERS-----------PELVGTFMV
:
MMAR_0237|M.marinum_M VRAENA----DQTGGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPG
MUL_4876|M.ulcerans_Agy99 VRAENA----DQTGGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPG
Mb0149|M.bovis_AF2122/97 TVLESQ----RHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVS
Rv0144|M.tuberculosis_H37Rv TVLESQ----RHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVS
MAV_5151|M.avium_104 GVLESQ----RHPEWNTAENDSVRIAREFLIRVVNDAIEHGEVAADIDAS
Mflv_3637|M.gilvum_PYR-GCK ARIDHHGARIGTGEGRGAATDIVSTVHDFYDAVVLAAAARGELPAGHDPH
MSMEG_1565|M.smegmatis_MC2_155 APIDAR----RHRELAESFATQGARMADALTDAVRSGQDAGDIAADLDPV
MAB_3372|M.abscessus_ATCC_1997 EAPRPP-------EFLAMLHRSEDAVIAAAEAVLAAHPEVRVTETDTAAR
TH_4573|M.thermoresistible__bu DAELMR-------HMIADADAAVRRTTEFLMPYVQQAKERGEVGSGVDVK
MLBr_02677|M.leprae_Br4923 RDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYESAMAIRRHHR
Mvan_4204|M.vanbaalenii_PYR-1 LLAENLAP---DAPLHDRLHQRYRAAADIIKDLITRGQQKGLYRKDFDAA
:
MMAR_0237|M.marinum_M AAVDAICALTRGLTEQAANLGP-QSYDVTLDSAKQLL--------RGSLF
MUL_4876|M.ulcerans_Agy99 AAVDAICALTRGLTEQAANLGP-QSYDVTLDSAKQLL--------RGSLF
Mb0149|M.bovis_AF2122/97 SLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLL--------AGTLW
Rv0144|M.tuberculosis_H37Rv SLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLL--------AGTLW
MAV_5151|M.avium_104 ALVETLLVVMCGVGLYAGYVETYQEMLAVTGMLRQLL--------EGALW
Mflv_3637|M.gilvum_PYR-GCK AVADMLAAVFWGLGFHARMLTADIGVDGVPEVARQLLSVLDSGLLDGALR
MSMEG_1565|M.smegmatis_MC2_155 RVARLISAVVDGFAHAAVSADP-DEMDNMNELFQSLL-----------LD
MAB_3372|M.abscessus_ATCC_1997 MVVATIESLVHRLIAGPRPIDPQLFEDQLVDMLTRYLTG-----------
TH_4573|M.thermoresistible__bu AASEWLARIIYSFTTVNEGLTFDMSKPATVRRYVERFAVN-------GLR
MLBr_02677|M.leprae_Br4923 LPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKRGEL
Mvan_4204|M.vanbaalenii_PYR-1 TKATEILAFINGMEIQ-WLLDPSIPLTEVYQGYAESLAR--------DLA
MMAR_0237|M.marinum_M AGAKPTATHRT
MUL_4876|M.ulcerans_Agy99 AGAKPTATRRT
Mb0149|M.bovis_AF2122/97 RPPT-------
Rv0144|M.tuberculosis_H37Rv RPPT-------
MAV_5151|M.avium_104 RPGS-------
Mflv_3637|M.gilvum_PYR-GCK APADA------
MSMEG_1565|M.smegmatis_MC2_155 TT---------
MAB_3372|M.abscessus_ATCC_1997 -----------
TH_4573|M.thermoresistible__bu -----------
MLBr_02677|M.leprae_Br4923 LPRAATSSLL-
Mvan_4204|M.vanbaalenii_PYR-1 AQPSPT-----