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LPRGNRRPGRPPAAKADETRQRIIQAARLVFSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVM DETNEFVIGVGIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQRHPEWNTAENDSVRIA REFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGVGLYAGYVETYQEMLAVTGMLRQLLEGALWRPGS *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5151 | - | - | 100% (211) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1159 | - | 5e-09 | 40.62% (64) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5267 | - | 2e-08 | 24.10% (166) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 2e-73 | 65.02% (203) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0744 | - | 3e-56 | 52.97% (202) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 2e-73 | 65.02% (203) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-05 | 32.43% (74) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 3e-10 | 27.32% (194) | transcriptional regulator TetR |
| M. marinum M | MMAR_0355 | - | 7e-64 | 56.31% (206) | TetR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0092 | - | 2e-58 | 54.19% (203) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1278 | - | 5e-32 | 45.45% (143) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_4765 | - | 5e-64 | 56.31% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0103 | - | 2e-47 | 50.54% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MMAR_0355|M.marinum_M --------------------------------------------------
MUL_4765|M.ulcerans_Agy99 --------------------------------------------------
MAV_5151|M.avium_104 --------------------------------------------------
Mflv_0744|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0103|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0092|M.smegmatis_MC2_155 --------------------------------------------------
TH_1278|M.thermoresistible__bu --------------------------------------------------
MAB_2290|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 -------------------------------------------------M
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MMAR_0355|M.marinum_M -------------------MQLTASRGPGRPPAAKADDTRRRIVGAAREV
MUL_4765|M.ulcerans_Agy99 ------------------MMQLTASRGPGRPPAAKADDTRRRIVGAAREV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
Mflv_0744|M.gilvum_PYR-GCK -------------MWHNFNVPYTASRGPGRPPAAKAAETRERILRAAREV
Mvan_0103|M.vanbaalenii_PYR-1 -------------------------------------------MRAAREI
MSMEG_0092|M.smegmatis_MC2_155 -------------------MAHIASRGPGRPPAAKAAETRERILSAAREV
TH_1278|M.thermoresistible__bu --------------------------------------------------
MAB_2290|M.abscessus_ATCC_1997 ----------------------MSESKPGRR-ERYAALTRSAIVEAARML
MLBr_00815|M.leprae_Br4923 NNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASDV
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVA
MMAR_0355|M.marinum_M FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MUL_4765|M.ulcerans_Agy99 FSERGYDGATFQAIAVSADLTRPAINHYFASKQALYREVVVQTNELVVAA
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDETNEFVIGV
Mflv_0744|M.gilvum_PYR-GCK FSELGYDAATFQAIAIRADLTRPAINHYFASKGVLWAEVVEQTNATIVSE
Mvan_0103|M.vanbaalenii_PYR-1 FSELGYDAATFQAIAVRADLTRPAINHYFSSKRVLWAEVVEQTYASVVGV
MSMEG_0092|M.smegmatis_MC2_155 FSELGYDAATFQAIAIRADLTRPAINHYFGSKRVLYREVVEQTNATVIAA
TH_1278|M.thermoresistible__bu ---------------------------------VLYQEVVQQTNSLVVAE
MAB_2290|M.abscessus_ATCC_1997 FVERGFDDTSVDDIAEAAQVSKGAIYHHFKDKQEIFIDVYRDATKGVIEN
MLBr_00815|M.leprae_Br4923 FVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVSS
:: * ::
Mb0149|M.bovis_AF2122/97 GIERARREPT-LMGRLAVVVDFAMEADAQYPASTAFL--ATTVLESQRHP
Rv0144|M.tuberculosis_H37Rv GIERARREPT-LMGRLAVVVDFAMEADAQYPASTAFL--ATTVLESQRHP
MMAR_0355|M.marinum_M GVERARSVQT-LLGQLCTFVMVAKEADASHPATTAFL--ATAVLESQRHP
MUL_4765|M.ulcerans_Agy99 GVERARSVQT-LLGQLCTFVMVAKEADASHPATTAFL--ATAVLESQRHP
MAV_5151|M.avium_104 GIKEADRETT-LVGRLTAFISAAVKANAENPAGSAFI--IGGVLESQRHP
Mflv_0744|M.gilvum_PYR-GCK AIARAHEHTS-LIERLSAFLTVATQAESDDRSAAAFL--VTSVLESQRHP
Mvan_0103|M.vanbaalenii_PYR-1 GIARAHEQTS-LLNRLMAFLSVATQVDTDDRSAAAFL--VTSVLESQRHP
MSMEG_0092|M.smegmatis_MC2_155 GVARAREATS-LLGRLSAFFAAAMDAESADRSSAAFL--VTSVLESQRHP
TH_1278|M.thermoresistible__bu GMERAKRETT-LLGRLSAFFTAAMQAESEDRSTAAFL--VISVLESQRHP
MAB_2290|M.abscessus_ATCC_1997 VVKVLIDVPAGSWNRIEAAASAVIKGYTDNREPRVLVRQVMGVLGAERTQ
MLBr_00815|M.leprae_Br4923 -VQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
: : :: . . :: : ..
Mb0149|M.bovis_AF2122/97 ELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGV
Rv0144|M.tuberculosis_H37Rv ELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGV
MMAR_0355|M.marinum_M ELRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGV
MUL_4765|M.ulcerans_Agy99 ELRRSDHDAVAATREFLDTAVRDAIQRGELEAGVDASQLAEALLLLLCGV
MAV_5151|M.avium_104 EWNTAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVMCGV
Mflv_0744|M.gilvum_PYR-GCK ELINDEHDSLKNSRRFVSAAVSDAIERGELSADTDVTHLVEMLVAVVWGM
Mvan_0103|M.vanbaalenii_PYR-1 ELADDDHDSLTNSRAFVSWAVNDAVARGELSADTDVNHLVEMLVAVVWGM
MSMEG_0092|M.smegmatis_MC2_155 DLVSEEQDALLNSRKFVAWAVNDAIERGELTTDTDIPAIVEMLVAVMWGM
TH_1278|M.thermoresistible__bu ELTIDEFDALKNSRAFVTWAVNDAIERGELTTNTDVSKIVEMLVAVLWGM
MAB_2290|M.abscessus_ATCC_1997 ALEG------ELALPLIRTLLTEAEENGELR-DLSIEKASQLIFRVLCES
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALIS-------ADSRLDPHRARMVAVGLVGISVDCA
:: ..: : :
Mb0149|M.bovis_AF2122/97 GFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT--------
Rv0144|M.tuberculosis_H37Rv GFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT--------
MMAR_0355|M.marinum_M GFYAGFVGSYRDMENILDTLCKMMAGTLWKPRS--------
MUL_4765|M.ulcerans_Agy99 GFYAGFVGSYRDMENILDTLCKMMAGTLWKPRS--------
MAV_5151|M.avium_104 GLYAGYVETYQEMLAVTGMLRQLLEGALWRPGS--------
Mflv_0744|M.gilvum_PYR-GCK GFYAGFVGDRSDLSAVVHKLELLLAGKLWNVAD--------
Mvan_0103|M.vanbaalenii_PYR-1 GFYAGFVGDRSDFGAVMHKLELLLANKLWNLGE--------
MSMEG_0092|M.smegmatis_MC2_155 GFYAGYVGRSEELAAIVDKFEMLMANKLWQLRD--------
TH_1278|M.thermoresistible__bu GFYAGYVGRQEDLKTVVEQFELLLANKLWQLKS--------
MAB_2290|M.abscessus_ATCC_1997 SLLIANSADYAEAAQEVETVMLCMFAGLRKPPAATRGRRKS
MLBr_00815|M.leprae_Br4923 RYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL------
.