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MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRCVAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELL NATATEIEEIVLPRLHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENADQTGGGRRTYPG SKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALTRGLTEQAANLGPQSYDVTLDSAKQLLRGSLFA GAKPTATRRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4876 | - | - | 100% (220) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4875 | - | 3e-49 | 50.49% (206) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4765 | - | 1e-14 | 26.77% (198) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0149 | - | 5e-17 | 28.79% (198) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 9e-16 | 30.50% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0144 | - | 5e-17 | 28.79% (198) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 3e-06 | 28.32% (113) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3372 | - | 3e-09 | 36.19% (105) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0237 | - | 1e-111 | 99.51% (205) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5151 | - | 9e-13 | 26.77% (198) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 2e-21 | 31.05% (190) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3831 | - | 5e-09 | 28.40% (169) | PUTATIVE putative transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_2776 | - | 9e-12 | 29.08% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4876|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0237|M.marinum_M --------------------------------------------------
Mb0149|M.bovis_AF2122/97 MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
Rv0144|M.tuberculosis_H37Rv MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSV
MAV_5151|M.avium_104 --------------------------------------------------
TH_3831|M.thermoresistible__bu --------------------------------------------------
Mflv_3637|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2776|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1565|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3372|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01733|M.leprae_Br4923 -----------------------------MTRRSIHTRKPLKWSGCAGQH
MUL_4876|M.ulcerans_Agy99 ----------------MTVPTFSTRSQLGRPVGARGEQTRQRIITAAMRC
MMAR_0237|M.marinum_M -------------------------------MGARGEQTRQRIITAAMRC
Mb0149|M.bovis_AF2122/97 ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
Rv0144|M.tuberculosis_H37Rv ASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQV
MAV_5151|M.avium_104 -------------------MLPRGNRRPGRPPAAKADETRQRIIQAARLV
TH_3831|M.thermoresistible__bu ----------------------------MRPARTASSDTRARILEAARRI
Mflv_3637|M.gilvum_PYR-GCK --------------MENETLSVSAGRKRGRPVAADSEQTRRTVLAAARDI
Mvan_2776|M.vanbaalenii_PYR-1 ---------------------MPAVRRPGRPVGANSDQTRRTILCAARDV
MSMEG_1565|M.smegmatis_MC2_155 -----------------MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRC
MAB_3372|M.abscessus_ATCC_1997 -------MAILAFGEGFDIMSSSRLQPRKQPRQDRAEATRRRILEAAAHV
MLBr_01733|M.leprae_Br4923 VRSGKVFDVGRISLSYPSMKPGVKIDARSERWREHRKKVRGEIVDAAFRA
.* :: **
MUL_4876|M.ulcerans_Agy99 VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEI--EEIVL
MMAR_0237|M.marinum_M VAEAGPAQASIREIAKAADMTSGSLYHYFPNKSELLNATATEI--EEIVL
Mb0149|M.bovis_AF2122/97 FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQT--HELVI
Rv0144|M.tuberculosis_H37Rv FSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQT--HELVI
MAV_5151|M.avium_104 FSERGYDGATFQAIAARADLTRPAINHYFSSKRALYQEVMDET--NEFVI
TH_3831|M.thermoresistible__bu IVERGYPAATCQGIARAAGVSRPTLHYYFASREEIYDCLVEQS--RNLLA
Mflv_3637|M.gilvum_PYR-GCK IAERGYQATTFQQIAQRAGVSRPTLHYYFATREDLYDALLADV--CERLG
Mvan_2776|M.vanbaalenii_PYR-1 IAEHGYRAATFQQIALRAGVSRPTLHYYFATREQLYEVLLADV--RAEVA
MSMEG_1565|M.smegmatis_MC2_155 FAQFGYGPATNNQIAEMAGVTAGSVYYHFGTKNKLFEAVCDDV--YGKIL
MAB_3372|M.abscessus_ATCC_1997 FADFGYAAGTTNRIAERAEISIGSLYQYFPNKDAILVELMTAHTHRGFAL
MLBr_01733|M.leprae_Br4923 LDRLG-PEVSVREIAEEAGTAKPKIYRHFTDKSDLFEAIGIRLR-DMLWA
. * : . ** * : : :* : :
MUL_4876|M.ulcerans_Agy99 PRLHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENA----
MMAR_0237|M.marinum_M PRLHAAAASSDDIVDRLDAVLDESKRLMRDYPYLAGFLRAVRAENA----
Mb0149|M.bovis_AF2122/97 VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQ----
Rv0144|M.tuberculosis_H37Rv VAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQ----
MAV_5151|M.avium_104 GVGIKEADRETTLVGRLTAFISAAVKANAENPAGSAFIIGGVLESQ----
TH_3831|M.thermoresistible__bu EC-AERAMRYDTLVERLTEFGLRLREVDSRDRSTIAFLISARLEGM----
Mflv_3637|M.gilvum_PYR-GCK RCAAAAAGQ-DSLRGQLAAFMAEMNRLAVAEPAMMKLVVTARIDHHGARI
Mvan_2776|M.vanbaalenii_PYR-1 RCAAEATLA-GSLLRQLEVFIAEMHRLGGAEPALMGLVVTARVDHRGVLR
MSMEG_1565|M.smegmatis_MC2_155 TRVMLAVSGSHSVVGLLRAVLTESMRINHESPELAGFVATAPIDAR----
MAB_3372|M.abscessus_ATCC_1997 IHQHLAAGLPDTIEDTVRVFVGSAIANHRDSPRLHRVLFEEAPRPP----
MLBr_01733|M.leprae_Br4923 AIFPAIDLATDSAREIIRRSVDEYVSLVDKHPNVLRVFIQGRFSAQS---
: ..
MUL_4876|M.ulcerans_Agy99 DQTGGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALT
MMAR_0237|M.marinum_M DQTGGGRRTYPGSKALRDVITEIVDDARGRGVLSAGIAPGAAVDAICALT
Mb0149|M.bovis_AF2122/97 RHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVL
Rv0144|M.tuberculosis_H37Rv RHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVL
MAV_5151|M.avium_104 RHPEWNTAENDSVRIAREFLIRVVNDAIEHGEVAADIDASALVETLLVVM
TH_3831|M.thermoresistible__bu RNRELG---EDPAMALREFFTELLADAVAAGELPSDIDIESAVEVMYTVL
Mflv_3637|M.gilvum_PYR-GCK GTGEGRGAATDIVSTVHDFYDAVVLAAAARGELPAGHDPHAVADMLAAVF
Mvan_2776|M.vanbaalenii_PYR-1 -----HEAATAVVATVHAFFDAVVVDAVRRGELAFDTDAHAVADLLGALF
MSMEG_1565|M.smegmatis_MC2_155 RHRELAESFATQGARMADALTDAVRSGQDAGDIAADLDPVRVARLISAVV
MAB_3372|M.abscessus_ATCC_1997 ---EFLAMLHRSEDAVIAAAEAVLAAHPEVRVTETDTAARMVVATIESLV
MLBr_01733|M.leprae_Br4923 ---EATVRTLDEGREITLTMAEMFNNELREMELNRAASELAAFAAFGSVA
. : :
MUL_4876|M.ulcerans_Agy99 RGLTEQAANLGP----QSYDVTLDSAKQLLRGSLFAGAKPTATRRT----
MMAR_0237|M.marinum_M RGLTEQAANLGP----QSYDVTLDSAKQLLRGSLFAGAKPTATHRT----
Mb0149|M.bovis_AF2122/97 CGVGFYIGFVGS---YQRMATITDSFQQLLAGTLWRPPT-----------
Rv0144|M.tuberculosis_H37Rv CGVGFYIGFVGS---YQRMATITDSFQQLLAGTLWRPPT-----------
MAV_5151|M.avium_104 CGVGLYAGYVET---YQEMLAVTGMLRQLLEGALWRPGS-----------
TH_3831|M.thermoresistible__bu WGLGFYTGFVER---STDMLVLAEQLENLFASA-----------------
Mflv_3637|M.gilvum_PYR-GCK WGLGFHARMLTADIGVDGVPEVARQLLSVLDSGLLDGALRAPADA-----
Mvan_2776|M.vanbaalenii_PYR-1 WGLVFHAGFIS---GADGAPEIARQLLRMVGFGLLDTPEPASVDA-----
MSMEG_1565|M.smegmatis_MC2_155 DGFAHAAVSADP----DEMDNMNELFQSLLLDTT----------------
MAB_3372|M.abscessus_ATCC_1997 HRLIAGPRPIDP-------QLFEDQLVDMLTRYLTG--------------
MLBr_01733|M.leprae_Br4923 SATEWWLGPEPDSPRRMPREQFVAHLTIIMMAVIVGTAETLGISMNPDRP
:.
MUL_4876|M.ulcerans_Agy99 ------------
MMAR_0237|M.marinum_M ------------
Mb0149|M.bovis_AF2122/97 ------------
Rv0144|M.tuberculosis_H37Rv ------------
MAV_5151|M.avium_104 ------------
TH_3831|M.thermoresistible__bu ------------
Mflv_3637|M.gilvum_PYR-GCK ------------
Mvan_2776|M.vanbaalenii_PYR-1 ------------
MSMEG_1565|M.smegmatis_MC2_155 ------------
MAB_3372|M.abscessus_ATCC_1997 ------------
MLBr_01733|M.leprae_Br4923 IHDAVPLDRSAS