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TPAQLRAFSAVVRLGSVRAAAEELGVSDAGVSMHVAQLRKELDDPLFTRTASGLAFTPGGLRLASRAVEI LGLQQQTAIEVTEAAHGRRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPARQFGHLITSRAVD IALGPAAPADPNLVVRAFLKYQIITVTTPDNALLERGVTPASLREQPWQLGPSGGNADGEIAAMLRALAI PEARQRIFQSDAAALEEVRRVGGVTPTIGFAVAKDLAGGRLAQVKGPGLQVGGEWFATTLPASARQPAVS ELLRFITTPRCTQAMIRGSGVGVSRFRPKVHVTLWS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0742 | - | - | 100% (317) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_3260 | - | 1e-11 | 26.05% (215) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3972 | - | 8e-11 | 32.37% (139) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 1e-134 | 78.19% (321) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 9e-08 | 28.80% (191) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 1e-133 | 77.88% (321) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 4e-05 | 29.93% (137) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3458c | - | 5e-10 | 25.19% (262) | LysR family transcriptional regulator |
| M. marinum M | MMAR_0653 | - | 1e-135 | 79.13% (321) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 2e-11 | 26.09% (299) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0172 | - | 1e-128 | 74.21% (318) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0119 | - | 1e-128 | 77.74% (310) | LysR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 2e-08 | 23.75% (261) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0384|M.bovis_AF2122/97 ---------------------MTP-----AQLRAYSAVVRLGSVRAAAAE
Rv0377|M.tuberculosis_H37Rv ---------------------MTP-----AQLRAYSAVVRLGSVRAAAAE
MMAR_0653|M.marinum_M ---------------------MTP-----AQLRAYSAVVRLGSVRAAATE
MUL_0119|M.ulcerans_Agy99 -------------------------------------MVRLGSVRAAATE
MSMEG_0742|M.smegmatis_MC2_155 ---------------------MTP-----AQLRAFSAVVRLGSVRAAAEE
TH_0172|M.thermoresistible__bu ---------------------MTP-----AQLRAFSAVVRLGSVRAAAQE
MAB_3458c|M.abscessus_ATCC_199 -------------------MALPPGTPDLGVLDLLVSVAETGSLGAAARQ
MAV_2151|M.avium_104 -------------------MPLSPRMPELASFEAFLAIAETGSLGRAARE
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
MLBr_02041|M.leprae_Br4923 -------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASF
Mvan_3401|M.vanbaalenii_PYR-1 --------------------------MDTRRLELLLALSRLGSMRAVADA
: . . .*
Mb0384|M.bovis_AF2122/97 LGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGL
Rv0377|M.tuberculosis_H37Rv LGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGL
MMAR_0653|M.marinum_M LGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGL
MUL_0119|M.ulcerans_Agy99 LGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASGAVEILGL
MSMEG_0742|M.smegmatis_MC2_155 LGVSDAGVSMHVAQLRKELDDPLFTRTASGLAFTPGGLRLASRAVEILGL
TH_0172|M.thermoresistible__bu LGMSDAGISMHIAQLRKELDDPLFHRTKNGLSFTPGGLRLASRAVDILGL
MAB_3458c|M.abscessus_ATCC_199 HGISQPAASMRIRALERRLRLVLLERGPTGSRLTDAGLAVVGYASPVLAA
MAV_2151|M.avium_104 LGLTQQAISRRLATMEAQIGVTLAVRTTRGSQLTPAGLIVADWAARLLEV
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
Mvan_3401|M.vanbaalenii_PYR-1 HHLTTSTVSQQIAALARDTGAALIEPEGRRVRLTPAGKRLADHAVTILAA
: * : : * .* * : * :
Mb0384|M.bovis_AF2122/97 QQQTAIEVTEAAHG-RRLLRIAASSAFAEHAAPGLIELFSSR-----ADD
Rv0377|M.tuberculosis_H37Rv QQQTAIEVTEAAHG-RRLLRIAASSAFAEHAAPGLIELFSSR-----ADD
MMAR_0653|M.marinum_M QQQTAIEVTEAAHG-RRLLRIAASSTFAEHAAPGLIELFSSR-----ADD
MUL_0119|M.ulcerans_Agy99 QQQTAIEVTEAAHG-RRLLRIAASSTFAEHAAPGLIELFSSR-----ADD
MSMEG_0742|M.smegmatis_MC2_155 QQQTAIEVTEAAHG-RRLLRIAASSAFAEHAAPGLIELFSSR-----ADD
TH_0172|M.thermoresistible__bu QRQTAIEVTEAAHG-RRLLRIAASHAFAEHAAPGLIDLFSSR-----ADD
MAB_3458c|M.abscessus_ATCC_199 AHEFVTGVAALHSDQAPRLVVAASRTIADHRIPLWLTALRAR-----HAD
MAV_2151|M.avium_104 AHEIDAGLGSLRKEGRERIRVAASQTISEQLMPHWLLSLQAEATRRGEAA
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELP---AVA
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHR-----LPT
Mvan_3401|M.vanbaalenii_PYR-1 VDRARLDLDPDAEP-AGTVRVGGFATGIRVSLLPIVADLAVR-----YPE
: :. : . .
Mb0384|M.bovis_AF2122/97 LSVELSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQ
Rv0377|M.tuberculosis_H37Rv LSVELSVHPTSRFRELICSRAVDIAIG-PASESSIGSDGSIFLRPFLKYQ
MMAR_0653|M.marinum_M LSVELSVHPTSQFRDLICSRAVDIAIG-PASESSIGSDTSLFVRPFLKYQ
MUL_0119|M.ulcerans_Agy99 LSVELSVHPTSQFRDLICARAVDIAIG-PASESSIGSDTSLFVRPFLKYQ
MSMEG_0742|M.smegmatis_MC2_155 LSVELSVHPARQFGHLITSRAVDIALG-PAAP----ADPNLVVRAFLKYQ
TH_0172|M.thermoresistible__bu LSVELTVEPVSRFRDLLESRAVDVTLG-PAVRE---PGPAIVVRPFLNYQ
MAB_3458c|M.abscessus_ATCC_199 VAVSLEVGNTQQVCELVRAGGASLGFI-EGPHAPTGLGGEVLG----ADE
MAV_2151|M.avium_104 PQVILTATNSEHAIASVRDGSADLGFV-ENPGTPKGLGSCVVG----EDE
Mflv_1356|M.gilvum_PYR-GCK LDIHADLLTPDQCEG-LRTGALDVGVL-RPPA----VGGDVATRTIAAEP
MLBr_02041|M.leprae_Br4923 LTLRVVEDQTEHLLTALREGALDAAMI-ALPVET----AGIAEIPIYDED
Mvan_3401|M.vanbaalenii_PYR-1 VDVVISEYEPVEAFKLLTADDLDLALTYDYNLAPASPGADLDAVPLWSIG
: . : . . :
Mb0384|M.bovis_AF2122/97 IITVVAPNSPLAAG--IPMPALLRHQQWMLGPSAGSVDG----EIATMLR
Rv0377|M.tuberculosis_H37Rv IITVVAPNSPLAAG--IPMPALLRHQQWMLGPSAGSVDG----EIATMLR
MMAR_0653|M.marinum_M IITVVAPNSPLAVG--IPTPSLLRQQQWMLGPPAGSVAG----EIATMLR
MUL_0119|M.ulcerans_Agy99 IITVVAPNSPLAVG--IPTPSLLRQQQWMLGPPAGSVAG----EIATMLR
MSMEG_0742|M.smegmatis_MC2_155 IITVTTPDNALLER--GVTPASLREQPWQLGPSGGNADG----EIAAMLR
TH_0172|M.thermoresistible__bu IIAVTSPSNPLAAA--TPTIAQLRAQSWMLGPSAGGIDG----DVAAMLR
MAB_3458c|M.abscessus_ATCC_199 LVIVVGPGHKWAHRRKPVTLRELAITPLLMREPGSGTRD----TVWEVLS
MAV_2151|M.avium_104 LVIVVPPTHKWARRSRVVTARELAQTPLVAREPHSGIRDSLTVALRKVLG
Mflv_1356|M.gilvum_PYR-GCK LVLAVSADHRLAAEP-VVSLADLRSEPFIGYTGQDSAVN-------DAVT
MLBr_02041|M.leprae_Br4923 FVLALPPGHPLSGKR-RVPTTALAQLPLLLLDEGHCLRD----QTLDICR
Mvan_3401|M.vanbaalenii_PYR-1 WGLGVPSGTAADRG-----LMTFADSTWIVNSRNTADET--------AVR
. :
Mb0384|M.bovis_AF2122/97 GLAIPESQQRIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTG
Rv0377|M.tuberculosis_H37Rv GLAIPESQQRIFQSDAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTG
MMAR_0653|M.marinum_M DLAIPESQQRIFQSDAAALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTS
MUL_0119|M.ulcerans_Agy99 DLAIPESQQRIFQSDAAALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTS
MSMEG_0742|M.smegmatis_MC2_155 ALAIPEARQRIFQSDAAALEEVRRVGGVTPTIGFAVAKDLAGGRLAQVKG
TH_0172|M.thermoresistible__bu RLEIPEAAQRIFQSDSAAQEEVQRIGGVTLSIGFAVAKDLAAGRLARIKG
MAB_3458c|M.abscessus_ATCC_199 EVCQPATPAAELGSAAAIKAAAATGLAPAVLSRLIAGPELSAGTLVEVKP
MAV_2151|M.avium_104 EDMQQAAPVLELTSAAAMRAAVLAGAGPAAMSRLAVADDLAVGRLHAVEI
Mflv_1356|M.gilvum_PYR-GCK RSCRAAGFVPHREHSAPGTAVLLALVAADLGVSVVPASVRALPLHGVVFR
MLBr_02041|M.leprae_Br4923 KSGVQAELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQ
Mvan_3401|M.vanbaalenii_PYR-1 TLASLAGFTPTIAHQIDSLDLVEDLIVAGFGVGLLPLGRPTSPGVTVLPL
: :
Mb0384|M.bovis_AF2122/97 PGLDRAGEWCVATLAPSARQPAVSELVGFISTPRCIQAMIRGSGVGVTRF
Rv0377|M.tuberculosis_H37Rv PGLDRAGEWCVATLAPSARQPAVSELVGFISTPRCIQAMIPGSGVGVTRF
MMAR_0653|M.marinum_M PGLDKAGEWCVATLPPAARQPAVSELVRFITTPRCIQAMIRGSGVGVTRF
MUL_0119|M.ulcerans_Agy99 PGLDKAGEWCVATLPPAARQPAVSELVRFITTPRCIQAMIRGSGVGVTRF
MSMEG_0742|M.smegmatis_MC2_155 PGLQVGGEWFATTLPASARQPAVSELLRFITTPRCTQAMIRGSGVGVSRF
TH_0172|M.thermoresistible__bu --VQATAEWCVSTLSSAARQPAASELVRFITTPRCTQAMIRGTSEGVTRF
MAB_3458c|M.abscessus_ATCC_199 ADGTVFTRQFRAVWRPG-APPTG-----------AARALVD--IAALVD-
MAV_2151|M.avium_104 PK-LDLRRKFRAIWIGGRTPPAG-----------AIRDLLSHIIARTAAS
Mflv_1356|M.gilvum_PYR-GCK DLVDGGTVDLALAWRDGVDNPVVD----------AVVAVLAGALTSLDHP
MLBr_02041|M.leprae_Br4923 FAAPCPGRRIGLAFRSASGRSASYR---------QIAKIIGELISTEHHV
Mvan_3401|M.vanbaalenii_PYR-1 QNPDVTLTAYAVTRRGRSAWSPLRAILDR---MRPPAGLLQHPTWPRPEA
. ::
Mb0384|M.bovis_AF2122/97 RPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv RPKVHVTLWS
MMAR_0653|M.marinum_M RPKVHVTLWS
MUL_0119|M.ulcerans_Agy99 RPKMHVTLWS
MSMEG_0742|M.smegmatis_MC2_155 RPKVHVTLWS
TH_0172|M.thermoresistible__bu RPKVHVTLWS
MAB_3458c|M.abscessus_ATCC_199 ----------
MAV_2151|M.avium_104 K---------
Mflv_1356|M.gilvum_PYR-GCK ALQEQS----
MLBr_02041|M.leprae_Br4923 RLVA------
Mvan_3401|M.vanbaalenii_PYR-1 AVANQSA---