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VVRLGSVRAAATELGLSDAGVSMHVAALRKELDDPLFTRTGAGLAFTPGGLRLASGAVEILGLQQQTAIE VTEAAHGRRLLRIAASSTFAEHAAPGLIELFSSRADDLSVELSVHPTSQFRDLICARAVDIAIGPASESS IGSDTSLFVRPFLKYQIITVVAPNSPLAVGIPTPSLLRQQQWMLGPPAGSVAGEIATMLRDLAIPESQQR IFQSDAAALEEVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAGEWCVATLPPAARQPAVSELVRFI TTPRCIQAMIRGSGVGVTRFRPKMHVTLWS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0119 | - | - | 100% (310) | LysR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_2698 | - | 7e-15 | 27.80% (295) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 1e-159 | 92.26% (310) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1833 | - | 5e-07 | 26.67% (165) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 1e-158 | 91.94% (310) | LysR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3458c | - | 7e-11 | 26.25% (259) | LysR family transcriptional regulator |
| M. marinum M | MMAR_0653 | - | 1e-170 | 99.03% (310) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2151 | - | 9e-12 | 24.83% (298) | LysR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0742 | - | 1e-128 | 77.74% (310) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0172 | - | 1e-121 | 71.61% (310) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 4e-07 | 28.37% (141) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0119|M.ulcerans_Agy99 ------------------MVRLGSVRAAATELGLSDAGVSMHVAALRKEL
MMAR_0653|M.marinum_M --MTP-----AQLRAYSAVVRLGSVRAAATELGLSDAGVSMHVAALRKEL
Mb0384|M.bovis_AF2122/97 --MTP-----AQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
Rv0377|M.tuberculosis_H37Rv --MTP-----AQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALRKEL
MSMEG_0742|M.smegmatis_MC2_155 --MTP-----AQLRAFSAVVRLGSVRAAAEELGVSDAGVSMHVAQLRKEL
TH_0172|M.thermoresistible__bu --MTP-----AQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLRKEL
MAB_3458c|M.abscessus_ATCC_199 MALPPGTPDLGVLDLLVSVAETGSLGAAARQHGISQPAASMRIRALERRL
MAV_2151|M.avium_104 MPLSPRMPELASFEAFLAIAETGSLGRAARELGLTQQAISRRLATMEAQI
Mflv_1833|M.gilvum_PYR-GCK --MDT-----HRLKYFLRIAEEGSITRAASLLGMAQPALSRQLQLLEEDL
Mvan_3401|M.vanbaalenii_PYR-1 --MDT-----RRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDT
: . **: .* :: * :: :
MUL_0119|M.ulcerans_Agy99 DDPLFTRTGAGLAFTPGGLRLASGAVEILGLQQQTAIEVTEAAHG-RRLL
MMAR_0653|M.marinum_M DDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLL
Mb0384|M.bovis_AF2122/97 DDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLL
Rv0377|M.tuberculosis_H37Rv DDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLL
MSMEG_0742|M.smegmatis_MC2_155 DDPLFTRTASGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHG-RRLL
TH_0172|M.thermoresistible__bu DDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHG-RRLL
MAB_3458c|M.abscessus_ATCC_199 RLVLLERGPTGSRLTDAGLAVVGYASPVLAAAHEFVTGVAALHSDQAPRL
MAV_2151|M.avium_104 GVTLAVRTTRGSQLTPAGLIVADWAARLLEVAHEIDAGLGSLRKEGRERI
Mflv_1833|M.gilvum_PYR-GCK GVALFRRNRRGVELTDAGERLRSSTAAPLRQLELAVQYAAFPLARLKRAM
Mvan_3401|M.vanbaalenii_PYR-1 GAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDPDAEP-AGTV
* :* .* : . : * :
MUL_0119|M.ulcerans_Agy99 RIAASSTFAEHAAPGLIELFSSR-----ADDLSVELSVHPTSQFRDLICA
MMAR_0653|M.marinum_M RIAASSTFAEHAAPGLIELFSSR-----ADDLSVELSVHPTSQFRDLICS
Mb0384|M.bovis_AF2122/97 RIAASSAFAEHAAPGLIELFSSR-----ADDLSVELSVHPTSRFRELICS
Rv0377|M.tuberculosis_H37Rv RIAASSAFAEHAAPGLIELFSSR-----ADDLSVELSVHPTSRFRELICS
MSMEG_0742|M.smegmatis_MC2_155 RIAASSAFAEHAAPGLIELFSSR-----ADDLSVELSVHPARQFGHLITS
TH_0172|M.thermoresistible__bu RIAASHAFAEHAAPGLIDLFSSR-----ADDLSVELTVEPVSRFRDLLES
MAB_3458c|M.abscessus_ATCC_199 VVAASRTIADHRIPLWLTALRAR-----HADVAVSLEVGNTQQVCELVRA
MAV_2151|M.avium_104 RVAASQTISEQLMPHWLLSLQAEATRRGEAAPQVILTATNSEHAIASVRD
Mflv_1833|M.gilvum_PYR-GCK LIGIPESAIDVLAAPLMTRLGSA-----FPDAQFAVTVGSTDHLVEAMLK
Mvan_3401|M.vanbaalenii_PYR-1 RVGGFATGIRVSLLPIVADLAVR-----YPEVDVVISEYEPVEAFKLLTA
:. : : : . : . :
MUL_0119|M.ulcerans_Agy99 RAVDIAIGPASESSIGSDTSLFVRPFLKYQIITVVAPNSPLAVG--IPTP
MMAR_0653|M.marinum_M RAVDIAIGPASESSIGSDTSLFVRPFLKYQIITVVAPNSPLAVG--IPTP
Mb0384|M.bovis_AF2122/97 RAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAG--IPMP
Rv0377|M.tuberculosis_H37Rv RAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAG--IPMP
MSMEG_0742|M.smegmatis_MC2_155 RAVDIALGPAAP----ADPNLVVRAFLKYQIITVTTPDNALLER--GVTP
TH_0172|M.thermoresistible__bu RAVDVTLGPAVRE---PGPAIVVRPFLNYQIIAVTSPSNPLAAA--TPTI
MAB_3458c|M.abscessus_ATCC_199 GGASLGFIEGPHAPTGLGGEVLG----ADELVIVVGPGHKWAHRRKPVTL
MAV_2151|M.avium_104 GSADLGFVENPGTPKGLGSCVVG----EDELVIVVPPTHKWARRSRVVTA
Mflv_1833|M.gilvum_PYR-GCK GSVDIALINPVP-----DDRVFYREILTEEFVLVGGPDSPLEPE-KPLQF
Mvan_3401|M.vanbaalenii_PYR-1 DDLDLALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSGTAADR----GL
.: : . : *
MUL_0119|M.ulcerans_Agy99 SLLRQQQWMLGPPAGSVAG----EIATMLRDLAIPESQQRIFQSDAAALE
MMAR_0653|M.marinum_M SLLRQQQWMLGPPAGSVAG----EIATMLRDLAIPESQQRIFQSDAAALE
Mb0384|M.bovis_AF2122/97 ALLRHQQWMLGPSAGSVDG----EIATMLRGLAIPESQQRIFQSDAAALE
Rv0377|M.tuberculosis_H37Rv ALLRHQQWMLGPSAGSVDG----EIATMLRGLAIPESQQRIFQSDAAALE
MSMEG_0742|M.smegmatis_MC2_155 ASLREQPWQLGPSGGNADG----EIAAMLRALAIPEARQRIFQSDAAALE
TH_0172|M.thermoresistible__bu AQLRAQSWMLGPSAGGIDG----DVAAMLRRLEIPEAAQRIFQSDSAAQE
MAB_3458c|M.abscessus_ATCC_199 RELAITPLLMREPGSGTRD----TVWEVLSEVCQPATPAAELGSAAAIKA
MAV_2151|M.avium_104 RELAQTPLVAREPHSGIRDSLTVALRKVLGEDMQQAAPVLELTSAAAMRA
Mflv_1833|M.gilvum_PYR-GCK ADLVELPLVVPRSTTGLGQ----ALYNAALRAKVTIDYRITTDSTRVMVC
Mvan_3401|M.vanbaalenii_PYR-1 MTFADSTWIVNSRNTADET----AVRTLASLAGFTPTIAHQIDSLDLVED
: : *
MUL_0119|M.ulcerans_Agy99 EVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAGEWCVATLPPAARQ
MMAR_0653|M.marinum_M EVMRVGGATLTIGFAVAKDLAAGRLVHVTSPGLDKAGEWCVATLPPAARQ
Mb0384|M.bovis_AF2122/97 EVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQ
Rv0377|M.tuberculosis_H37Rv EVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQ
MSMEG_0742|M.smegmatis_MC2_155 EVRRVGGVTPTIGFAVAKDLAGGRLAQVKGPGLQVGGEWFATTLPASARQ
TH_0172|M.thermoresistible__bu EVQRIGGVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSAARQ
MAB_3458c|M.abscessus_ATCC_199 AAATGLAPAVLSRLIAGPELSAGTLVEVKPADGTVFTRQFRAVWRPG-AP
MAV_2151|M.avium_104 AVLAGAGPAAMSRLAVADDLAVGRLHAVEIPK-LDLRRKFRAIWIGGRTP
Mflv_1833|M.gilvum_PYR-GCK LIESGLAYGVLPLSACGREFAESRLRYSRICEPVLTQQLGVAATEQLDLP
Mvan_3401|M.vanbaalenii_PYR-1 LIVAGFGVGLLP---LGRPTSPGVTVLPLQNPDVTLTAYAVTRRGRSAWS
. . : . :
MUL_0119|M.ulcerans_Agy99 PAVSELVRFITTPRCIQAMIRGSGVGVTRFRPKMHVTLWS
MMAR_0653|M.marinum_M PAVSELVRFITTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Mb0384|M.bovis_AF2122/97 PAVSELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv PAVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
MSMEG_0742|M.smegmatis_MC2_155 PAVSELLRFITTPRCTQAMIRGSGVGVSRFRPKVHVTLWS
TH_0172|M.thermoresistible__bu PAASELVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
MAB_3458c|M.abscessus_ATCC_199 PTG-----------AARALVD--IAALVD-----------
MAV_2151|M.avium_104 PAG-----------AIRDLLSHIIARTAASK---------
Mflv_1833|M.gilvum_PYR-GCK RELVVKVG-NALREEIAALIRSGSWRADLLSPEPWSPRRV
Mvan_3401|M.vanbaalenii_PYR-1 PLRAILDR----MRPPAGLLQHPTWPRPEAAVANQSA---
::