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MEWTLRELRVFVTAADTGSFTDAAAQLHVSQAAVSRTIAGLEKIVGDRLLRRVPRGCELTAAGQQILPLA RRVLAEAESFTEFLHSRHGVLRLGYAWAAVGRHTARLQRDWAQRQADIELELVRHNSPTAGLAEGLCDVA VIRRPTDEKRFASVIVGLERRLVAFASDDEQWSGRRQLSMAEIADRTVIIDPRIGTTSSELWEGSGHVPQ FIVSTDVDTWLDAIAAGRGVGTTAEATAHHHPRHGVTYRPIKDGPRIAVRLAWWRDHRPRGLDELVDAVT RLYST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0471 | - | - | 100% (285) | transcriptional regulator LysR family protein |
| M. smegmatis MC2 155 | MSMEG_5654 | - | 5e-19 | 28.62% (276) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_1909 | - | 1e-17 | 28.94% (273) | putative HTH-type transcriptional regulator YnfL |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-11 | 29.56% (203) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1356 | - | 2e-18 | 29.62% (287) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 2e-11 | 29.56% (203) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 6e-10 | 24.35% (193) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 2e-16 | 27.76% (281) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 9e-11 | 30.08% (256) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2789 | - | 4e-23 | 28.95% (266) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-13 | 27.27% (275) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 1e-11 | 29.96% (247) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4518 | - | 9e-26 | 31.14% (289) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4157|M.marinum_M --------------------------MELYQLRYFQAVAECGTLRGASEQ
MUL_4020|M.ulcerans_Agy99 --------------------------MELYQLRYFQAVAECGTLRGASEQ
Mb2303c|M.bovis_AF2122/97 -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
Rv2282c|M.tuberculosis_H37Rv -------------------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARE
MAB_2238|M.abscessus_ATCC_1997 --------------------------MEIHQLRYLLAVADTSSFTKAAAA
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
MAV_2789|M.avium_104 ----------MKDLCSSGMDVVQAGRVELRHLRAFEAVARLESFTLAAQE
MSMEG_0471|M.smegmatis_MC2_155 ------------------------MEWTLRELRVFVTAADTGSFTDAAAQ
Mvan_4518|M.vanbaalenii_PYR-1 --------------------------MTLRQLRYFAVLGHELNYRRAAEK
TH_3504|M.thermoresistible__bu ---------------------VPSPKIDLRRLAQFVAVAELGSFTRAAAT
MLBr_02041|M.leprae_Br4923 -------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASF
: : : . *:
MMAR_4157|M.marinum_M LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
MUL_4020|M.ulcerans_Agy99 LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
Mb2303c|M.bovis_AF2122/97 LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
Rv2282c|M.tuberculosis_H37Rv LGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
MAB_2238|M.abscessus_ATCC_1997 LHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAA
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
MAV_2789|M.avium_104 LSITQPALSRTIKQLEDALEASLLDRTSRHVATTPAGRVFLGHVERILTE
MSMEG_0471|M.smegmatis_MC2_155 LHVSQAAVSRTIAGLEKIVGDRLLRRVPRGCELTAAGQQILPLARRVLAE
Mvan_4518|M.vanbaalenii_PYR-1 LFITQPALSTAIKQLEHQFGVVLFHRNTREVALTDLGAAWLPQVQQALSG
TH_3504|M.thermoresistible__bu LHLSQQALSSAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAA
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
* : * :* : :* . * * * . *
MMAR_4157|M.marinum_M VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR--
MUL_4020|M.ulcerans_Agy99 VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIR-LHHSRFPQAR--
Mb2303c|M.bovis_AF2122/97 ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
Rv2282c|M.tuberculosis_H37Rv ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTV
MAB_2238|M.abscessus_ATCC_1997 VDGVREAADEIGGLIRGHIAFGTVTSHGADLSS--LLSAFHRDHPAIS--
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIAR-IVRQELPAVALD
MAV_2789|M.avium_104 LGRGVDAVRQQAS-----IRLGFSWLLPDPWAQDTVARFERTTRTTVS--
MSMEG_0471|M.smegmatis_MC2_155 AESFTEFLHSRHGVLRLGYAWAAVGRHTARLQRDWAQRQADIELELVR--
Mvan_4518|M.vanbaalenii_PYR-1 VDAVVDNLIMLSGTRRGVLRVGYLIGTGADLLFRLVRHFEAAYPDVTVEP
TH_3504|M.thermoresistible__bu ARTVAEHVRQTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFT-
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLR-
MMAR_4157|M.marinum_M --FELHQRSGQGVLSDLVSGVTDVS-LSFPAA-FEGYGEIAWQTLFTQQL
MUL_4020|M.ulcerans_Agy99 --FELHQRSGQGVLSDLVSGVTDVS-LSFPAA-FEGYGEIAWQTLFTQQL
Mb2303c|M.bovis_AF2122/97 PEVILTATNSEHAIAAVRDGIADLGFIENPCP-PTGLGSVVVAR---DEL
Rv2282c|M.tuberculosis_H37Rv PEVILTATNSEHAIAAVRDGIADLGFIENPCP-PTGLGSVVVAR---DEL
MAB_2238|M.abscessus_ATCC_1997 --ITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVIDD---QPL
Mflv_1356|M.gilvum_PYR-GCK ---IHADLLTPDQCEGLRTGALDVGVLRPPAV----GGDVATRTIAAEPL
MAV_2789|M.avium_104 ------LIRTDDALGAVQQGRVDIALVRGHVT----STAVRIVHLFDEPR
MSMEG_0471|M.smegmatis_MC2_155 ---------HNSPTAGLAEGLCDVAVIRRPTD---EKRFASVIVGLERRL
Mvan_4518|M.vanbaalenii_PYR-1 -----IEFDFADPTAGLADGTTEVAIIRPPVD----LPEHRMLILDSESW
TH_3504|M.thermoresistible__bu ----LRQLYPDALTDAVFDGTVQLGLRRGVVP----TPELATAVIGYHRV
MLBr_02041|M.leprae_Br4923 ----VVEDQTEHLLTALREGALDAAMIALPVE----TAGIAEIPIYDEDF
: * : .
MMAR_4157|M.marinum_M YAVVSTDHPLAGR-RLIRFPELAAYPFVVLD--RDHTLRRIVDAACARHG
MUL_4020|M.ulcerans_Agy99 YAVVSTDHPLAGR-RLIRFPELAAYPFVVLD--RDHTLRRIVDAACARHG
Mb2303c|M.bovis_AF2122/97 VVVVPPGHKWARRSRVVSARELAQTPLVTRE--PNSGIRDSLTAALRDTL
Rv2282c|M.tuberculosis_H37Rv VVVVPPGHKWARRSRVVSARELAQTPLVTRE--PNSGIRDSLTAALRDTL
MAB_2238|M.abscessus_ATCC_1997 VAAVAADDLLATR-RTITLQRLCEHTLICLP--TGSGVRSILESECRSLG
Mflv_1356|M.gilvum_PYR-GCK VLAVSADHRLAAE-PVVSLADLRSEPFIGYTG-QDSAVNDAVTRSCRAAG
MAV_2789|M.avium_104 VAVCSVHSPLAKR-AKLDWAEVPRWPLVINT------ASGTTGPWSWPAG
MSMEG_0471|M.smegmatis_MC2_155 VAFASDDEQWSGR-RQLSMAEIADRTVIIDP-----RIGTTSSELWEGSG
Mvan_4518|M.vanbaalenii_PYR-1 VACLPRDHRLAER-REVEIAELLDDPIVCAP-----LTAGTWRDYWLAMD
TH_3504|M.thermoresistible__bu RVAFVDSHPLAAR-ESVDITELAREQVALWAPPGTSYYSDFLMGACRRAG
MLBr_02041|M.leprae_Br4923 VLALPPGHPLSGK-RRVPTTALAQLPLLLLD--EGHCLRDQTLDICRKSG
: . : : .
MMAR_4157|M.marinum_M ----IDPTLAFEGTDVGTLRGLIGANLGVGVLPQATARP------ADIIE
MUL_4020|M.ulcerans_Agy99 ----IDPTPAFEGTDVGTLRGLIGANLGVGVLPQATARP------ADIIE
Mb2303c|M.bovis_AF2122/97 GEDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLA--FGRLLA
Rv2282c|M.tuberculosis_H37Rv GEDMQQAPPVLELSSAAAVRAAVLAGAGPAAMSRLAIADDLA--FGRLLA
MAB_2238|M.abscessus_ATCC_1997 ----LSPNVAFEASSPRALVSLVEQGLGIAVVPAPYVRN-----RAGVLA
Mflv_1356|M.gilvum_PYR-GCK ----FVPHREHSAPGTAVLLALVAADLGVSVVP-ASVRALPL--HGVVFR
MAV_2789|M.avium_104 ----DGPETIVETTNFDEWIESVAADRGIGVIPDVAIRRNVH--PGVRFV
MSMEG_0471|M.smegmatis_MC2_155 -----HVPQFIVSTDVDTWLDAIAAGRGVGTTAEATAHHHPR--HGVTYR
Mvan_4518|M.vanbaalenii_PYR-1 VRGNRPPTIAAVAATYEAETTAIARGLGISFTTSSVARFYDR--PGIVYV
TH_3504|M.thermoresistible__bu ----FEPDYVVSRVQGAATVAAPLTTGGIAFVTAAAGPTMN---GRVQVV
MLBr_02041|M.leprae_Br4923 ---VQAELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQ
* .
MMAR_4157|M.marinum_M IAIDDAQLVRPIAIGWIADRCLPSSAVAFRETALGCYGHRVSAAGV
MUL_4020|M.ulcerans_Agy99 IAIDDAQLVRPIAIGWIADRCLPSSAVAFRETAFGCYGHRDSAAGV
Mb2303c|M.bovis_AF2122/97 VDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST-------
Rv2282c|M.tuberculosis_H37Rv VDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST-------
MAB_2238|M.abscessus_ATCC_1997 LDIR-PALRGRLALAWRLDGPVGPAARAFLERARAVL---------
Mflv_1356|M.gilvum_PYR-GCK DLVDGGTVDLALAWRDGVDNPVVDAVVAVLAGALTSLDHPALQEQS
MAV_2789|M.avium_104 ALRDAPDIPVALAFVKRASGPVLRRFIEAAVDAAANQ---------
MSMEG_0471|M.smegmatis_MC2_155 PIKDGPRIAVRLAWWRDHRPRGLDELVDAVTRLYST----------
Mvan_4518|M.vanbaalenii_PYR-1 PICDRPPSHTALAWNPADLTPQADALVRHVQSQWSFGDGDNADHG-
TH_3504|M.thermoresistible__bu DLTPPLLVPVQALWQRHTLSAIRDRILEGLG---------------
MLBr_02041|M.leprae_Br4923 FAAPCPGRRIGLAFRSASGRSASYRQIAKIIGELISTEHHVRLVA-