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MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARA ALAAVDGVREAADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAISITLTEAGCEELVAGLREGRL DGAIVALGAQRLAGLGLQVIDDQPLVAAVAADDLLATRRTITLQRLCEHTLICLPTGSGVRSILESECRS LGLSPNVAFEASSPRALVSLVEQGLGIAVVPAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARA FLERARAVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2238 | - | - | 100% (289) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3208c | - | 4e-56 | 44.32% (273) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0055c | - | 1e-36 | 35.86% (290) | DNA-binding transcriptional regulator CynR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 4e-21 | 28.33% (293) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_3565 | - | 4e-72 | 49.48% (289) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 4e-21 | 28.33% (293) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-23 | 31.73% (271) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 3e-25 | 29.86% (288) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_4979 | - | 4e-26 | 31.60% (288) | transcriptional regulator, LysR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 3e-72 | 50.35% (286) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-20 | 28.67% (279) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 4e-25 | 29.86% (288) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 6e-73 | 50.34% (290) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3565|M.gilvum_PYR-GCK -----------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVS
Mvan_3362|M.vanbaalenii_PYR-1 -----------------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVS
MSMEG_3840|M.smegmatis_MC2_155 -----------------MELRQLEYFVAVAEEANFTRAAQRIHVAQPAVS
MAB_2238|M.abscessus_ATCC_1997 -----------------MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVS
MMAR_4157|M.marinum_M -----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVS
MUL_4020|M.ulcerans_Agy99 -----------------MELYQLRYFQAVAECGTLRGASEQLLVSQSAVS
Mb0121|M.bovis_AF2122/97 -----------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALS
Rv0117|M.tuberculosis_H37Rv -----------------MLFRQLEYFVAVAQERHFARAAEKCYVSQPALS
MLBr_02041|M.leprae_Br4923 ----------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLS
MAV_4979|M.avium_104 MLLAVSAVGGPESRCVMATLLQLKAFLAVVDQGGFTAASRSLGMSQPAVS
TH_3504|M.thermoresistible__bu ------------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALS
: * : *:.: : *: : * :*
Mflv_3565|M.gilvum_PYR-GCK AQIRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVD
Mvan_3362|M.vanbaalenii_PYR-1 AQIRRLERQVGQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVD
MSMEG_3840|M.smegmatis_MC2_155 ASIRQLERELGQPLFDRSRREVRLTAAGEAVLPHAHAALRSVAAARTAVA
MAB_2238|M.abscessus_ATCC_1997 AQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVREAAD
MMAR_4157|M.marinum_M RAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVR
MUL_4020|M.ulcerans_Agy99 RAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRSVSSAIDNVR
Mb0121|M.bovis_AF2122/97 SAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVD
Rv0117|M.tuberculosis_H37Rv SAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAEHAAFKAEVD
MLBr_02041|M.leprae_Br4923 QALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAA
MAV_4979|M.avium_104 RAVAGLERELGSPLLIRHRDRILLNAPGKRALAHARSAVRHLDQMRAEVS
TH_3504|M.thermoresistible__bu SAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVR
: ** :. *: * :. * : .: .
Mflv_3565|M.gilvum_PYR-GCK DVAGLLRGSVAIGTVTLHPMN-VAHLIAEFHADHPDVEITLGT-ATSDVL
Mvan_3362|M.vanbaalenii_PYR-1 DVANLVRGAVAIGTVTLHPVD-VARLMADFHAEHPGVEITLGT-DTSDVL
MSMEG_3840|M.smegmatis_MC2_155 EVSGLVRGSVVVGTVTAHDFD-MAGLLAEFHGAHQLVDITLGT-DESDAL
MAB_2238|M.abscessus_ATCC_1997 EIGGLIRGHIAFGTVTSHGAD-LSSLLSAFHRDHPAISITLTE-AGCEEL
MMAR_4157|M.marinum_M ELAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQ-RSGQGV
MUL_4020|M.ulcerans_Agy99 ELAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFELHQ-RSGQGV
Mb0121|M.bovis_AF2122/97 AVRSGITGTLRLGTVPTASTT-ASLVLSAFCSAHPLAKVQVCSRLAATEL
Rv0117|M.tuberculosis_H37Rv AVRSGITGTLRLGTVPTASTT-ASLVLSAFCSAHPLAKVQVCSRLAATEL
MLBr_02041|M.leprae_Br4923 GESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVE-DQTEHL
MAV_4979|M.avium_104 -AAAKLRGTLRIASLPYTTELLIAPQLQKFSERHPSVEIRVLE-GGEPEI
TH_3504|M.thermoresistible__bu QTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLRQ-LYPDAL
. .. : . : :
Mflv_3565|M.gilvum_PYR-GCK IAELGDGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHRRS
Mvan_3362|M.vanbaalenii_PYR-1 LAKLEDGRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARRKS
MSMEG_3840|M.smegmatis_MC2_155 IDGLLAGRLDAAIISVGSG-LPEGLAAEVVTDQRIVAAVGDGHPWRRRRR
MAB_2238|M.abscessus_ATCC_1997 VAGLREGRLDGAIVALGAQ-RLAGLGLQVIDDQPLVAAVAADDLLATRRT
MMAR_4157|M.marinum_M LSDLVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRL
MUL_4020|M.ulcerans_Agy99 LSDLVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVSTDHPLAGRRL
Mb0121|M.bovis_AF2122/97 YRRLREFELDAVIVHPETQ-DSDDVDLVPLYEEQYVLLSPADMLPPGTST
Rv0117|M.tuberculosis_H37Rv YRRLREFELDAVIVHPETQ-DSDDVDLVPLYEEQYVLLSPADMLPPGTST
MLBr_02041|M.leprae_Br4923 LTALREGALDAAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGKRR
MAV_4979|M.avium_104 RDWLDLGAADAGVISLPAT----GLSAAFLAAQDMVAVLPSEHRLAAFSE
TH_3504|M.thermoresistible__bu TDAVFDGTVQLGLRRGVVP--TPELATAVIGYHRVRVAFVDSHPLAARES
: : : : : .
Mflv_3565|M.gilvum_PYR-GCK LSLEQLS--RHPLISLPAGTGLRTRLDTACAAAGLRPRIA-FEATSPAEL
Mvan_3362|M.vanbaalenii_PYR-1 LSLKQLC--EYPVISLPAGTGLRSRLDDACAAAGLRPRIA-FEATSPLEL
MSMEG_3840|M.smegmatis_MC2_155 IALTDLA--GVPLITLPRGTGIRRQLDRACRAAGVDVRVA-FEATTPGAL
MAB_2238|M.abscessus_ATCC_1997 ITLQRLC--EHTLICLPTGSGVRSILESECRSLGLSPNVA-FEASSPRAL
MMAR_4157|M.marinum_M IRFPELA--AYPFVVLDRDHTLRRIVDAACARHGIDPTLA-FEGTDVGTL
MUL_4020|M.ulcerans_Agy99 IRFPELA--AYPFVVLDRDHTLRRIVDAACARHGIDPTPA-FEGTDVGTL
Mb0121|M.bovis_AF2122/97 LVWRDAA--QLPLALLTADMRDRQVIDAAFADHAVSAIPQ-VETDSVASL
Rv0117|M.tuberculosis_H37Rv LVWRDAA--QLPLALLTADMRDRQVIDAAFADHAVSAIPQ-VETDSVASL
MLBr_02041|M.leprae_Br4923 VPTTALA--QLPLLLLDEGHCLRDQTLDICRKSGVQAELANTRAASLATA
MAV_4979|M.avium_104 VHYADLA--KEPFIRSTG--GCAHVFMAVADQVGVEFDVA-FEAHGLMAV
TH_3504|M.thermoresistible__bu VDITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATV
: . .. .. .
Mflv_3565|M.gilvum_PYR-GCK AELARHGLGVAILPQSMARGG--------SGLHALRLAPELRGRLVWAWR
Mvan_3362|M.vanbaalenii_PYR-1 ADLARHGLGVAILPRSMARGS--------AGLHPLRLSPELRGRLVWAWR
MSMEG_3840|M.smegmatis_MC2_155 ADLAERGLGAAVLPESVARAR--------AALHPLPITPELRGRLVFAWR
MAB_2238|M.abscessus_ATCC_1997 VSLVEQGLGIAVVPAPYVRNR--------AGVLALDIRPALRGRLALAWR
MMAR_4157|M.marinum_M RGLIGANLGVGVLPQATARPA--------DIIEIAIDDAQLVRPIAIGWI
MUL_4020|M.ulcerans_Agy99 RGLIGANLGVGVLPQATARPA--------DIIEIAIDDAQLVRPIAIGWI
Mb0121|M.bovis_AF2122/97 FAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATN
Rv0117|M.tuberculosis_H37Rv FAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATN
MLBr_02041|M.leprae_Br4923 VQCVTGGLGVTLLPQSAAPVESVR----SKLGLAQFAAPCPGRRIGLAFR
MAV_4979|M.avium_104 LEIVTAGLGVSIVPVAAVARPR-------AGIAVKRLVPKTTRNLAVAVS
TH_3504|M.thermoresistible__bu AAPLTTG-GIAFVTAAAGPTMN-------GRVQVVDLTPPLLVPVQALWQ
. .:. . . :
Mflv_3565|M.gilvum_PYR-GCK ADGAN-PAARVLGERARAMAVSPGSGAPAVVPGA--
Mvan_3362|M.vanbaalenii_PYR-1 TDISG-PAARLLNARARAMIAATG--TPAVIPGA--
MSMEG_3840|M.smegmatis_MC2_155 ATGPMSPAARALVTMARRRLGLGD---PDRVGGHE-
MAB_2238|M.abscessus_ATCC_1997 LDGPVGPAARAFLERARAVL----------------
MMAR_4157|M.marinum_M ADRCLPSSAVAFRETALGCYGHRVSAAGV-------
MUL_4020|M.ulcerans_Agy99 ADRCLPSSAVAFRETAFGCYGHRDSAAGV-------
Mb0121|M.bovis_AF2122/97 ALGPGSPVARALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv ALGPGSPVARALITCAQALALNEFFDTQLRGITRRR
MLBr_02041|M.leprae_Br4923 SASGRSASYRQIAKIIGELISTEHHVRLVA------
MAV_4979|M.avium_104 ASAGS--AARAFLEQIAALDGSERAGA---------
TH_3504|M.thermoresistible__bu RHTLSAIRDRILEGLG--------------------
: