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VELRHLRYFAAVADTCHFGQAAEQLHVAQPALSYAIRQLETELDVTLFYRTTRQVSLTPAGEFLRAEAAR ILAGVDDAERGVRRIARGRGGLLRLGLTGTAAFSHLPRIARIVKREMPDVALEIHADMLTPVQCDSLRSG ALDLGVLRPPAVGDGVELTVIDAESLVLAVSADHRLAAEPVVSMADLRAEPFVGYASRDSAVNDAVLRSC RSAGFVPDRAHTAPGTAVLLALVAADLGVAVVPESVRALPLDGVVFRDLLDGGTVELALAWRRAADRDSH ANPLVGSVVDILAPAPSRESVPSLEERL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1909 | - | - | 100% (308) | putative HTH-type transcriptional regulator YnfL |
| M. smegmatis MC2 155 | MSMEG_1895 | - | 3e-54 | 44.71% (255) | HTH-type transcriptional regulator AlsR |
| M. smegmatis MC2 155 | MSMEG_5654 | - | 2e-45 | 38.73% (284) | transcriptional regulator, LysR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0121 | oxyS | 1e-15 | 31.13% (257) | oxidative stress response regulatory protein OXYS |
| M. gilvum PYR-GCK | Mflv_1356 | - | 1e-126 | 75.24% (307) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0117 | oxyS | 1e-15 | 31.13% (257) | oxidative stress response regulatory protein OXYS |
| M. leprae Br4923 | MLBr_02041 | oxyR | 4e-20 | 31.20% (250) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 1e-28 | 36.75% (283) | LysR family transcriptional regulator |
| M. marinum M | MMAR_4157 | - | 1e-23 | 33.07% (254) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_1538 | - | 2e-26 | 31.40% (293) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 8e-19 | 28.16% (277) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_4020 | - | 9e-24 | 33.07% (254) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 3e-39 | 37.23% (274) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1909|M.smegmatis_MC2_155 --------------------------MELRHLRYFAAVADTCHFGQAAEQ
Mflv_1356|M.gilvum_PYR-GCK MVSAVTGRPTNDPPHTWRHRTIKEPPMELRHLRYFLAVAETCHFGQAAEQ
Mvan_1027|M.vanbaalenii_PYR-1 -------------------------MFSLARLSCFVAVAEELHFGRAAER
MMAR_4157|M.marinum_M --------------------------MELYQLRYFQAVAECGTLRGASEQ
MUL_4020|M.ulcerans_Agy99 --------------------------MELYQLRYFQAVAECGTLRGASEQ
Mb0121|M.bovis_AF2122/97 --------------------------MLFRQLEYFVAVAQERHFARAAEK
Rv0117|M.tuberculosis_H37Rv --------------------------MLFRQLEYFVAVAQERHFARAAEK
MAB_2238|M.abscessus_ATCC_1997 --------------------------MEIHQLRYLLAVADTSSFTKAAAA
MAV_1538|M.avium_104 --------------------------MAVGDYEWFITLAELQHVTAAAEQ
TH_3504|M.thermoresistible__bu ---------------------VPSPKIDLRRLAQFVAVAELGSFTRAAAT
MLBr_02041|M.leprae_Br4923 -------------------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASF
. : ::.: . *:
MSMEG_1909|M.smegmatis_MC2_155 LHVAQPALSYAIRQLETELDVTLFYRTTRQVSLTPAGEFLRAEAARILAG
Mflv_1356|M.gilvum_PYR-GCK LHIAQPALSYAIRQLENSLDATLFTRTTRHVALTPAGEFLRVEATRILNG
Mvan_1027|M.vanbaalenii_PYR-1 LHMTQPPLSRQVQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQL
MMAR_4157|M.marinum_M LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
MUL_4020|M.ulcerans_Agy99 LLVSQSAVSRAITLLEAEIGVQLFTRRGRTNELNRYGQALLVGSRLAQRS
Mb0121|M.bovis_AF2122/97 CYVSQPALSSAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAE
Rv0117|M.tuberculosis_H37Rv CYVSQPALSSAIAKLERELNVTLINRGHSFEGLTREGERLVVWAKRILAE
MAB_2238|M.abscessus_ATCC_1997 LHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAA
MAV_1538|M.avium_104 LHVAQPTLTRMLARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLE
TH_3504|M.thermoresistible__bu LHLSQQALSSAVRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAA
MLBr_02041|M.leprae_Br4923 LGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEA
: * :: : ** :. *: * :. * . .
MSMEG_1909|M.smegmatis_MC2_155 VDDAERGVRRIARGRGGLLRLGLTGTAAFSHLPRIARIVKREMPDVALEI
Mflv_1356|M.gilvum_PYR-GCK VDAAQRGVRRIAAGRSGLLRLGLTGTAAFSHLPKIARIVRQELPAVALDI
Mvan_1027|M.vanbaalenii_PYR-1 AEGAAQTVKRIPAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVKLDL
MMAR_4157|M.marinum_M VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFEL
MUL_4020|M.ulcerans_Agy99 VSSAIDNVRELAGVSGGTVALGFLHSLGMQTVPHLIRLHHSRFPQARFEL
Mb0121|M.bovis_AF2122/97 HAAFKAEVDAVRSGITGTLRLGTVPTASTTAS-LVLSAFCSAHPLAKVQV
Rv0117|M.tuberculosis_H37Rv HAAFKAEVDAVRSGITGTLRLGTVPTASTTAS-LVLSAFCSAHPLAKVQV
MAB_2238|M.abscessus_ATCC_1997 VDGVREAADEIGGLIRGHIAFGTVTSHG-ADLSSLLSAFHRDHPAISITL
MAV_1538|M.avium_104 LDSARRAIADLADPAVGEIRLAYLSSFGSTVVPRLIARFKESSPRVTFTL
TH_3504|M.thermoresistible__bu ARTVAEHVRQTEAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTL
MLBr_02041|M.leprae_Br4923 MDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRV
. .. : . : * . :
MSMEG_1909|M.smegmatis_MC2_155 HADMLTPVQCDSLRSGALDLGVLRPPAVG--DGVELTVIDAESLVLAVSA
Mflv_1356|M.gilvum_PYR-GCK HADLLTPDQCEGLRTGALDVGVLRPPAVG--GDVATRTIAAEPLVLAVSA
Mvan_1027|M.vanbaalenii_PYR-1 R-EMVTAAQIEGLMTGELDLGMARPPLKR--PGLVSRPLLHEQLLAALPE
MMAR_4157|M.marinum_M HQRSGQGVLSD-LVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVST
MUL_4020|M.ulcerans_Agy99 HQRSGQGVLSD-LVSGVTDVSLSFPAAFEGYGEIAWQTLFTQQLYAVVST
Mb0121|M.bovis_AF2122/97 CSRLAATELYRRLREFELDAVIVHPETQDS-DDVDLVPLYEEQYVLLSPA
Rv0117|M.tuberculosis_H37Rv CSRLAATELYRRLREFELDAVIVHPETQDS-DDVDLVPLYEEQYVLLSPA
MAB_2238|M.abscessus_ATCC_1997 T-EAGCEELVAGLREGRLDGAIVALGAQR-LAGLGLQVIDDQPLVAAVAA
MAV_1538|M.avium_104 E-EGAAESIADRVRSGGVDIGVVSPRPVER--TLAWRSLFRQRLGVAVPD
TH_3504|M.thermoresistible__bu R-QLYPDALTDAVFDGTVQLGLRRGVVPTP--ELATAVIGYHRVRVAFVD
MLBr_02041|M.leprae_Br4923 V-EDQTEHLLTALREGALDAAMIALPVET--AGIAEIPIYDEDFVLALPP
: : : : : .
MSMEG_1909|M.smegmatis_MC2_155 DHRLAAEP-VVSMADLRAEPFVGYASRDS-AVNDAVLRSCRSAGFVPDRA
Mflv_1356|M.gilvum_PYR-GCK DHRLAAEP-VVSLADLRSEPFIGYTGQDS-AVNDAVTRSCRAAGFVPHRE
Mvan_1027|M.vanbaalenii_PYR-1 GHPLADMTRELTLIDLDGQDFVMYSPVQARYFNELLISTFTIAGTTPRYV
MMAR_4157|M.marinum_M DHPLAGRR-LIRFPELAAYPFVVLDRDHT--LRRIVDAACARHGIDPTLA
MUL_4020|M.ulcerans_Agy99 DHPLAGRR-LIRFPELAAYPFVVLDRDHT--LRRIVDAACARHGIDPTPA
Mb0121|M.bovis_AF2122/97 DMLPPGTS-TLVWRDAAQLPLALLTADMR--DRQVIDAAFADHAVSAIPQ
Rv0117|M.tuberculosis_H37Rv DMLPPGTS-TLVWRDAAQLPLALLTADMR--DRQVIDAAFADHAVSAIPQ
MAB_2238|M.abscessus_ATCC_1997 DDLLATRR-TITLQRLCEHTLICLPTGSG--VRSILESECRSLGLSPNVA
MAV_1538|M.avium_104 GHRFARGA-AVSMVDLADEPFVTMHPGFG--MRRLLDELCAAAQFRPRVA
TH_3504|M.thermoresistible__bu SHPLAARE-SVDITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYV
MLBr_02041|M.leprae_Br4923 GHPLSGKR-RVPTTALAQLPLLLLDEGHC--LRDQTLDICRKSGVQAELA
. . : . .
MSMEG_1909|M.smegmatis_MC2_155 HTAPG-TAVLLALVAADLGVAVVP-ESVRALPLDGVVFRDL--LDGGTVE
Mflv_1356|M.gilvum_PYR-GCK HSAPG-TAVLLALVAADLGVSVVP-ASVRALPLHGVVFRDL--VDGGTVD
Mvan_1027|M.vanbaalenii_PYR-1 QYVTQ-VHTMLVLVRSGIGIALVP-ASAATLHPEGVVFRTIGAFRERPVE
MMAR_4157|M.marinum_M FEGTD-VGTLRGLIGANLGVGVLPQATARPADIIEIAIDDA----QLVRP
MUL_4020|M.ulcerans_Agy99 FEGTD-VGTLRGLIGANLGVGVLPQATARPADIIEIAIDDA----QLVRP
Mb0121|M.bovis_AF2122/97 VETDS-VASLFAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPV
Rv0117|M.tuberculosis_H37Rv VETDS-VASLFAQVATGNWASIVPHTWLWAMPMSGPTGGEIRAVELVDPV
MAB_2238|M.abscessus_ATCC_1997 FEASS-PRALVSLVEQGLGIAVVPAPYVRNR--AGVLALDIR--PALRGR
MAV_1538|M.avium_104 LQAPN-LTTAASLVAAGLGISLVPIDGSSYPSGVSVKPLAD---ADAYRD
TH_3504|M.thermoresistible__bu VSRVQ-GAATVAAPLTTGGIAFVTAAAGPTMNGRVQVVDLT---PPLLVP
MLBr_02041|M.leprae_Br4923 NTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRR
.:.
MSMEG_1909|M.smegmatis_MC2_155 LALAWRRAADRDSHANPLVGSVVDILAPAPSRESVPSLEERL----
Mflv_1356|M.gilvum_PYR-GCK LALAWRDGVD-----NPVVDAVVAVLAGALTSLDHPALQEQS----
Mvan_1027|M.vanbaalenii_PYR-1 LDAVWRGDSTN--------PALLRVLKDVLPQQEWTT---------
MMAR_4157|M.marinum_M IAIGWIADRCLP-------SSAVAFRETALGCYGHRVSAAGV----
MUL_4020|M.ulcerans_Agy99 IAIGWIADRCLP-------SSAVAFRETAFGCYGHRDSAAGV----
Mb0121|M.bovis_AF2122/97 LKAQIALATNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR
Rv0117|M.tuberculosis_H37Rv LKAQIALATNALGPGSPVARALITCAQALALNEFFDTQLRGITRRR
MAB_2238|M.abscessus_ATCC_1997 LALAWRLDGPVG-------PAARAFLERARAVL-------------
MAV_1538|M.avium_104 VGMIWDSGRPLP-------RSARDFIAGAAAVGHGGW---------
TH_3504|M.thermoresistible__bu VQALWQRHTLS---------AIRDRILEGLG---------------
MLBr_02041|M.leprae_Br4923 IGLAFRSASGRS----ASYRQIAKIIGELISTEHHVRLVA------
: