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VEARDRVAWRLNIKVAQQAQKLVYRYATRRLKDDDVVFLNYGYEEDPPMGIPLSESDELNRYSIQLYHST AAQADVEGKRVLEVGCGHGGGASYLARTFRPATYTGLDLNSDGINFCRRRHNIAGLEFVQGDAQDLPFPD KNFDAVLNVESSHLYPRFDVFLTEVARVLRPGGYFLYTDARPRYDIPEWERALADAPLQMLSQRAINFEV VRGMEKNLDALESVVDRVAPALLRDWIQKYGPARRAYEELRENTTEYRMYCFVKPAE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0393 | - | - | 100% (267) | Fmt protein |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 9e-10 | 38.00% (100) | hypothetical protein MSMEG_2350 |
| M. smegmatis MC2 155 | MSMEG_0098 | - | 5e-08 | 36.89% (103) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2976 | - | 7e-75 | 55.95% (252) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4060 | - | 2e-08 | 35.71% (98) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv2952 | - | 7e-75 | 55.95% (252) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_00130 | - | 1e-70 | 50.19% (257) | hypothetical protein MLBr_00130 |
| M. abscessus ATCC 19977 | MAB_4103c | - | 1e-102 | 67.68% (263) | methyltransferase |
| M. marinum M | MMAR_1766 | - | 8e-77 | 55.38% (260) | methyltransferase |
| M. avium 104 | MAV_2988 | - | 5e-10 | 37.00% (100) | ubiquinone/menaquinone biosynthesis methyltransferases |
| M. thermoresistible (build 8) | TH_1636 | - | 1e-106 | 68.91% (267) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_2377 | - | 2e-75 | 57.26% (248) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0109 | - | 2e-09 | 36.46% (96) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0393|M.smegmatis_MC2_155 ---MEARDRVAWRLNIKVAQQAQKLVYRYATRRLKDDDVVFLNYGYEEDP
TH_1636|M.thermoresistible__bu --VRESRDQVFRKLNEKLTQHGQKFIYSYASRRLDDDDVVFLNYGYEEDP
MAB_4103c|M.abscessus_ATCC_199 --MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEEEP
Mb2976|M.bovis_AF2122/97 MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDP
Rv2952|M.tuberculosis_H37Rv MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDP
MLBr_00130|M.leprae_Br4923 MAFTRIHSFLASAGNTSMYKRVWRFWYPLMTHKLGTDEIMFINWAYEEDP
MUL_2377|M.ulcerans_Agy99 MAFSPAHRLLARLGSTSIYKRVWRYWYPLMTRGLGADKIAFLNWAYEEDP
MMAR_1766|M.marinum_M MALSRTHRVVAGVAHTRVYKKIWKYWYPLMTRGLGADELVFINWAYEEDP
MAV_2988|M.avium_104 ------------MGQVTDHWRAARLASALYDTAAMHDRVAAVG----AKA
Mflv_4060|M.gilvum_PYR-GCK ----------------------MATVDNEDDRALKAKHRALWASGDYPAV
Mvan_0109|M.vanbaalenii_PYR-1 -MTHTVLRMTERLLIDPPEHPDTSKGYLDLLGDEPDSNRGAIQALWASRL
.
MSMEG_0393|M.smegmatis_MC2_155 PMGIPLSESDELNRYSIQLYHSTAAQADVEGKRVLEVGCGHGGGASYLAR
TH_1636|M.thermoresistible__bu PMGLPLSETDEPNRYSIQLYHRTAGQADLTGKRVLEVGCGHGGGASYLMR
MAB_4103c|M.abscessus_ATCC_199 AMGVPLSASDEPDRYSIQLYHSTATQADLGGQRVLEVGCGHGGGASYLVR
Mb2976|M.bovis_AF2122/97 PMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTR
Rv2952|M.tuberculosis_H37Rv PMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTR
MLBr_00130|M.leprae_Br4923 PMALPLEASDEPNRAHINLYHRTATQVNLSGKRILEVSCGHGGGASYLTR
MUL_2377|M.ulcerans_Agy99 PIDLTLEVSDEPNRDHINMYHRTATHVELSGKRVLEVSCGHGGGASYLTR
MMAR_1766|M.marinum_M PMDLPLEATDEPDRCHINLYHRTATQADLSGKRVLEVSCGHGGGASYLTR
MAV_2988|M.avium_104 LWGLALRDLLAEVR---------HVGAAPPGAYVLDIPCG-GGFAFRGLR
Mflv_4060|M.gilvum_PYR-GCK AAELIPSLGPELVR----------ACGVRSGDRVLDVAAGSGNAS--IPA
Mvan_0109|M.vanbaalenii_PYR-1 GSMFYDNAQTLARRLMTAWQQPTEWLNVPVGGTALDVGSGPGNVTGALGR
. * * *:: .* *. :
MSMEG_0393|M.smegmatis_MC2_155 TFRP-ATYTGLDLNSDGINFCRRRHNIAG----LEFVQGDAQDLPFPDKN
TH_1636|M.thermoresistible__bu TLGP-MSYVGLDLNPAGIEFCRKKHRLPG----LEFVVGDAQDLPFGAES
MAB_4103c|M.abscessus_ATCC_199 ALQP-ASYTGLDLNPDGISFCRRRHDLPG----LEFVQGDAEDLPFPDES
Mb2976|M.bovis_AF2122/97 TLHP-ASYTGLDLNQAGIKLCKKRHRLPG----LDFVRGDAENLPFDDES
Rv2952|M.tuberculosis_H37Rv TLHP-ASYTGLDLNQAGIKLCKKRHRLPG----LDFVRGDAENLPFDDES
MLBr_00130|M.leprae_Br4923 ALHP-ASYTGLDLNPAGIKLCQKRHQLPG----LEFVRGDAENLPFDNES
MUL_2377|M.ulcerans_Agy99 TLHP-ASYTGLDLNRAGIKLCQRRHNLPG----LDFVRGDAENLPFEDES
MMAR_1766|M.marinum_M TLGP-ASYTALDLNPAGIKFCQQRHHLPG----LDFVQGDAEDLPFEDES
MAV_2988|M.avium_104 AGQD-CRYVAADISSDMLRRARSRATRFGVANLMEFTEADITCLPFPDNT
Mflv_4060|M.gilvum_PYR-GCK AAAG-AVVTASDLTPELFDAGRRIAAERG--VAVEWVEADAEALPFPDDS
Mvan_0109|M.vanbaalenii_PYR-1 AVGPGGLALGVDISEPMLARAVRAEAGPN----VGFIRADAQHLPFRDES
: . *:. : . : : .* *** ..
MSMEG_0393|M.smegmatis_MC2_155 FDAVLNVESSHLYPRFDVFLTEVARVLRPGGYFLYTDARPRYDIPEWERA
TH_1636|M.thermoresistible__bu FDAVINIESSHLYPRFSRFLSEVARVLRPGGHFLYADARQPHEFAEWEAA
MAB_4103c|M.abscessus_ATCC_199 FDAVINVESSHLYPHFPVFLTEVARVLRPGGNFLYTDARSVQDVAGWKVA
Mb2976|M.bovis_AF2122/97 FDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEAD
Rv2952|M.tuberculosis_H37Rv FDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEAD
MLBr_00130|M.leprae_Br4923 FDVVINIEASHCYPHFPRFLAEVVRVLRPGGHLAYADLRPSNKVGEWEVD
MUL_2377|M.ulcerans_Agy99 FDVVLKVEASHCYPHFSRFLAEVVRVLRPGGYLLYTDLRPSNEIAEWEAD
MMAR_1766|M.marinum_M FDVVLNVEASHCYPRFPVFLEEVKRVLRPGGYFAYADIRPCTEIAEWEAA
MAV_2988|M.avium_104 FDLALTFNGLHCLPDPRAAVFELARVLKPGGILRGTTCVRGR---GWRQ-
Mflv_4060|M.gilvum_PYR-GCK FDVVMSCVGAMFAPHHQATADEIVRVTRPGGTLGLISWTPEGFIGHLFAT
Mvan_0109|M.vanbaalenii_PYR-1 FDAVVSIAMLQLIPDPAVALAEMVRVLRPGRRMAVMVPTAGPAAGLLRYL
** .:. * *: ** :** :
MSMEG_0393|M.smegmatis_MC2_155 LA---------DAPLQMLSQRAINFEVVRGMEKNLDALESVVDRVAPALL
TH_1636|M.thermoresistible__bu LA---------AAPLDMVSARVINAEVVRGMEQILPVWEDVIERVAPAFL
MAB_4103c|M.abscessus_ATCC_199 LA---------NAPLRMVSERGINAEVRRGMEKNLARWRYVIDRATPAPL
Mb2976|M.bovis_AF2122/97 LA---------ATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFL
Rv2952|M.tuberculosis_H37Rv LA---------ATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFL
MLBr_00130|M.leprae_Br4923 FA---------NSRLQQLSQREINAEVLRGIASNSQKSRDLVDRHLPAFL
MUL_2377|M.ulcerans_Agy99 LA---------GSPLRQLSQREINAEVVRGIEKNSHTSRVLVDRNLPAFL
MMAR_1766|M.marinum_M LA---------AAGLQQISHREINAEVLRGIDINTPKSRELVKRHLPIFL
MAV_2988|M.avium_104 -------------------DRFVTALQAAGFFGNTPGAGDVSR-------
Mflv_4060|M.gilvum_PYR-GCK MKPYAPPPPPGASPPPMWGSENHVEALFGDRVRDLTMRRQTVRFDHCASP
Mvan_0109|M.vanbaalenii_PYR-1 PN---------------AGAHAFGDDELGDTFESLGLAG-----------
. .
MSMEG_0393|M.smegmatis_MC2_155 RDWIQKY-GPARRAYEELR-ENTTEYRMYCFVKPAE--------------
TH_1636|M.thermoresistible__bu RRRVREF-APARRAWEELRTEGSTEYRMYCFTKPPEHADIP---------
MAB_4103c|M.abscessus_ATCC_199 RGIVRRF-APAQRAYDDLRAGGSVEYRMYRFVKA----------------
Mb2976|M.bovis_AF2122/97 RFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD----------------
Rv2952|M.tuberculosis_H37Rv RFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD----------------
MLBr_00130|M.leprae_Br4923 RFAGREFIGVQGTQLSRYLEGGELSYRMYSFAKD----------------
MUL_2377|M.ulcerans_Agy99 RFADR----AVGRQLSRYLEGGELSYRMYCFTKDFAASR-----------
MMAR_1766|M.marinum_M RAAGRNYIGATGTPLYRLMQSGDISYRMYCFVKE----------------
MAV_2988|M.avium_104 ------WLGEAGLEIVAARHSGSVELFEAVRPSA----------------
Mflv_4060|M.gilvum_PYR-GCK LDFREYWKRNYGPTLAAYRFNEDRPERLAELDAAFLDFLTTWNQADGTDG
Mvan_0109|M.vanbaalenii_PYR-1 ---------------VRINTVGTIQWVRGRKS------------------
MSMEG_0393|M.smegmatis_MC2_155 ---------------
TH_1636|M.thermoresistible__bu ---------------
MAB_4103c|M.abscessus_ATCC_199 ---------------
Mb2976|M.bovis_AF2122/97 ---------------
Rv2952|M.tuberculosis_H37Rv ---------------
MLBr_00130|M.leprae_Br4923 ---------------
MUL_2377|M.ulcerans_Agy99 ---------------
MMAR_1766|M.marinum_M ---------------
MAV_2988|M.avium_104 ---------------
Mflv_4060|M.gilvum_PYR-GCK TAYDAEYLLVTATKR
Mvan_0109|M.vanbaalenii_PYR-1 ---------------