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VDTALRRAMDLLIDPPAEPDFSKGYLDLLGRGDSTAPKNTGLIQKAWASPLGSKLYDRAQLLNRRLVAST RPPVEWLRIPPGGTVLDIGCGPGNITAQLARAAGLDGLALGVDISEPMLARAVAAEAGRQVGFVRADAQQ LPFRDEVFDAATSLAVFQLIPDPVAAVSEIVRVLKPGGRVAIMVPTAGAVKPVTFLARGGARIFGDDELG DIFENVGLVGVRVKTHGFIQWVRGTKL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0098 | - | - | 100% (237) | methyltransferase |
| M. smegmatis MC2 155 | MSMEG_6483 | - | 4e-14 | 34.90% (149) | methyltransferase type 11 |
| M. smegmatis MC2 155 | MSMEG_1115 | ubiE | 2e-12 | 41.51% (106) | ubiquinone/menaquinone biosynthesis methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0862 | - | 9e-14 | 42.31% (104) | hypothetical protein Mb0862 |
| M. gilvum PYR-GCK | Mflv_0738 | - | 3e-72 | 58.90% (236) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv0839 | - | 1e-13 | 42.31% (104) | hypothetical protein Rv0839 |
| M. leprae Br4923 | MLBr_02273 | ubiE | 2e-12 | 41.51% (106) | ubiquinone/menaquinone biosynthesis methyltransferase |
| M. abscessus ATCC 19977 | MAB_4018 | - | 1e-24 | 32.10% (243) | similarity with UbiE/COQ5 methyltransferase |
| M. marinum M | MMAR_4497 | - | 3e-31 | 37.12% (229) | methyltransferase |
| M. avium 104 | MAV_5229 | - | 2e-80 | 64.10% (234) | methyltransferase type 11 |
| M. thermoresistible (build 8) | TH_3395 | - | 2e-14 | 45.71% (105) | PUTATIVE putative ubiquinone/menaquinone biosynthesis |
| M. ulcerans Agy99 | MUL_4668 | - | 4e-31 | 37.12% (229) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0109 | - | 3e-78 | 62.98% (235) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0738|M.gilvum_PYR-GCK MTES------ALRMAERLLADPPEHPDVSKGYLDLLGDRPAGDA------
Mvan_0109|M.vanbaalenii_PYR-1 MTHT------VLRMTERLLIDPPEHPDTSKGYLDLLGDEPDSNR------
MAV_5229|M.avium_104 MTDVHTSLPPALRRALDLLIDPPADPDVSKGYLDLLGGAADEDAGVPRNT
MSMEG_0098|M.smegmatis_MC2_155 MDT-------ALRRAMDLLIDPPAEPDFSKGYLDLLGRGDSTAP---KNT
MMAR_4497|M.marinum_M MSATP-----DPRE--VTRGLLTEPCDLRRGFLDVLGESTSSPVPT----
MUL_4668|M.ulcerans_Agy99 MSATP-----DPRE--VTRGLLTEPGDLRHGFLDVLGESTSSPVPT----
MAB_4018|M.abscessus_ATCC_1997 MLHHP-----TLADSLIDPARIDHPPRRDHGYLDVLGPESDEPVS-----
Mb0862|M.bovis_AF2122/97 -----------MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVP
Rv0839|M.tuberculosis_H37Rv -----------MNDKRRAIYTHGYHESVLRSHRRRTAENSAGYLLPYLVP
TH_3395|M.thermoresistible__bu --------------MADVAANWAGRGGRFAGGLYDFG-------------
MLBr_02273|M.leprae_Br4923 --------------MPPGSVDVVSRAALDKDPRDVVAMFDDVAH------
. .
Mflv_0738|M.gilvum_PYR-GCK GAIQALWASRLGSLFYDNAQTVMRR---------VLTAWHEPTEWLNLPV
Mvan_0109|M.vanbaalenii_PYR-1 GAIQALWASRLGSMFYDNAQTLARR---------LMTAWQQPTEWLNVPV
MAV_5229|M.avium_104 GPIQAAWASPIGSLLYDNAQALSRR---------WISAWQLPLEWLQIPR
MSMEG_0098|M.smegmatis_MC2_155 GLIQKAWASPLGSKLYDRAQLLNRR---------LVASTRPPVEWLRIPP
MMAR_4497|M.marinum_M -VAQRAMNSRFVATVYERLWRPAAF--YLASGVTTRAEQHRAAAALHLST
MUL_4668|M.ulcerans_Agy99 -VAQRAMNSRFVATVYERLWRPAAF--YLASGVTTRAEQHRAAAALHLST
MAB_4018|M.abscessus_ATCC_1997 -VANRFMQSPLLAAIYERAWRPMFTRGFSYGGKSTLKAHTALMDEIAGRG
Mb0862|M.bovis_AF2122/97 GLSVLDVGCGPGTITVDLAARVVPG---------SVTGVEPTDDALSLAR
Rv0839|M.tuberculosis_H37Rv GLSVLDVGCGPGTITVDLAARVVPG---------SVTGVEPTDDALSLAR
TH_3395|M.thermoresistible__bu -VEREVLARPAGLLMWGTDTRLLFD---------------SIRRIGDLPD
MLBr_02273|M.leprae_Br4923 ---RYDLTNTVLSLGQDRYWRRATR------------------SALRIGP
Mflv_0738|M.gilvum_PYR-GCK GGVALDVGSGPGNVTAALGRAVGPGGLALGVDVSEPMLARAVAAEAGP--
Mvan_0109|M.vanbaalenii_PYR-1 GGTALDVGSGPGNVTGALGRAVGPGGLALGVDISEPMLARAVRAEAGP--
MAV_5229|M.avium_104 GGVALDVGSGPGNVTASLARAAGPDGLALGIDISEPMLARAVRNEAGP--
MSMEG_0098|M.smegmatis_MC2_155 GGTVLDIGCGPGNITAQLARAAGLDGLALGVDISEPMLARAVAAEAGR--
MMAR_4497|M.marinum_M AHRLLDVACGPGNFTAPLVKQLPAGSLAVGLDISEPMLTRAVLDNSGP--
MUL_4668|M.ulcerans_Agy99 AHRLLDVACGPGNFTAPLVKQLPAGSLAVGLDISEPMLTRAVLDNSGP--
MAB_4018|M.abscessus_ATCC_1997 DHKILDVACGPGLYTRELAAQLGTAGVCIGLDLSGPMLRRAVRDNSAE--
Mb0862|M.bovis_AF2122/97 AEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQ--
Rv0839|M.tuberculosis_H37Rv AEAQLHRLSNISFTTSDVHKLDFPDDAFDVVHAHQVLQHVADPVRALQ--
TH_3395|M.thermoresistible__bu GTAVLDIPCGGGLALRGLRHGRRLR--YVAADISADMLARAQRRAATLGR
MLBr_02273|M.leprae_Br4923 GQKVLDLAAGTAVSTAELSK---SGAWCVAADFSVRMLATGGARKVPK--
*. .. . : . : .
Mflv_0738|M.gilvum_PYR-GCK -NVGFLRADAQDLPLSDESVDGVVSIAMLQLIPEPARAVAEMVRVLR---
Mvan_0109|M.vanbaalenii_PYR-1 -NVGFIRADAQHLPFRDESFDAVVSIAMLQLIPDPAVALAEMVRVLR---
MAV_5229|M.avium_104 -QVGFIKADAQRLPLRDNTVDAAVSTAVLQLVPNPQAALVEIARVLR---
MSMEG_0098|M.smegmatis_MC2_155 -QVGFVRADAQQLPFRDEVFDAATSLAVFQLIPDPVAAVSEIVRVLK---
MMAR_4497|M.marinum_M -QTCYVRGDARMLPFDDETFDAVCCFGALYLMPEPFRIAREMVRVLG---
MUL_4668|M.ulcerans_Agy99 -QTCYVRGDARMLPFDDETFDAVCCFGALYLMPEPFRIAREMVRVLG---
MAB_4018|M.abscessus_ATCC_1997 -RVDYIRGSAHSLPFADATFDTVVCLAALYLIPDPEQAVRELCRVAG---
Mb0862|M.bovis_AF2122/97 -EMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEP
Rv0839|M.tuberculosis_H37Rv -EMRRVCTPGGIVAARDADYSGFIWFPKLPALDRWLDLYERAARANGGEP
TH_3395|M.thermoresistible__bu TDVRFVVADIERMPFGDGEFDCCVTFNGLHCVPDPAAAVAEIARCVK---
MLBr_02273|M.leprae_Br4923 -----VAADATQLPFSDGVFDAVTISFGLRNIADYQAALREMARVTR---
: :. * . : : . *
Mflv_0738|M.gilvum_PYR-GCK -SGRRVAVMVPTAG-----------------PAAAALRYLPHAG----AH
Mvan_0109|M.vanbaalenii_PYR-1 -PGRRMAVMVPTAG-----------------PAAGLLRYLPNAG----AH
MAV_5229|M.avium_104 -PGGRLAVMVPTAG-----------------RLARYWRLLPNVG----AH
MSMEG_0098|M.smegmatis_MC2_155 -PGGRVAIMVPTAG------------------AVKPVTFLARGG----AR
MMAR_4497|M.marinum_M -PGGRIAILTTYSG-----------------QRAPIRHALDAAAGAIGLT
MUL_4668|M.ulcerans_Agy99 -PGGRIAILTTYSG-----------------QRAPIRHALDAAAGAIGLT
MAB_4018|M.abscessus_ATCC_1997 -PDGQIVVFTSLR------------------TRAASLPGVTTAMRIGGFR
Mb0862|M.bovis_AF2122/97 DAGRRLLSWARAAGF------------DDVTPTASVWCFATASAREWWGL
Rv0839|M.tuberculosis_H37Rv DAGRRLLSWARAAGF------------DDVTPTASVWCFATASAREWWGL
TH_3395|M.thermoresistible__bu -PGGRLIGDAVVRG--------------AGRRQDALIAVFRRAG------
MLBr_02273|M.leprae_Br4923 -PGGQLVVCEFSTPTNALVANVYTEYLMRALPQVARLVSSNPDAYIYLAE
.. ::
Mflv_0738|M.gilvum_PYR-GCK SFGD----DELADVFEGLGLTSVRAN--TVGTIQWVRGKKP---------
Mvan_0109|M.vanbaalenii_PYR-1 AFGD----DELGDTFESLGLAGVRIN--TVGTIQWVRGRKS---------
MAV_5229|M.avium_104 AFDD----DEIGDILEENGFASVRVK--NFGTFQWVRAKLS---------
MSMEG_0098|M.smegmatis_MC2_155 IFGD----DELGDIFENVGLVGVRVK--THGFIQWVRGTKL---------
MMAR_4497|M.marinum_M MFDQ----DSFVDLFSSAGLVDIDQQ--TQRGLQFVVAAKPK--------
MUL_4668|M.ulcerans_Agy99 MFDQ----DSFVDLFSSAGLVDIDQQ--TQRGLQFVVAAKPK--------
MAB_4018|M.abscessus_ATCC_1997 AFGR----DEVTGWLRAQGWTDIDQT--VTGQGQFIRARRAVALRVAT--
Mb0862|M.bovis_AF2122/97 VWADRILQSDLAHQLVDSGLATAAQL--EEISTAWREWAAAPDGWLAIPH
Rv0839|M.tuberculosis_H37Rv VWADRILQSDLAHQLVDSGLATAAQL--EEISTAWREWAAAPDGWLAIPH
TH_3395|M.thermoresistible__bu VFGPGGTTDELQGWLTRAGFEVEDFR--RSGAVAHFTAVRS---------
MLBr_02273|M.leprae_Br4923 SIRAWPDQVTLACQLSRTGWASPRWRNLTGGIVALHAADKPVR-------
. : *
Mflv_0738|M.gilvum_PYR-GCK -------
Mvan_0109|M.vanbaalenii_PYR-1 -------
MAV_5229|M.avium_104 -------
MSMEG_0098|M.smegmatis_MC2_155 -------
MMAR_4497|M.marinum_M -------
MUL_4668|M.ulcerans_Agy99 -------
MAB_4018|M.abscessus_ATCC_1997 -------
Mb0862|M.bovis_AF2122/97 GEILCRA
Rv0839|M.tuberculosis_H37Rv GEILCRA
TH_3395|M.thermoresistible__bu -------
MLBr_02273|M.leprae_Br4923 -------