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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_1636 | - | 100% (275) | POSSIBLE METHYLTRANSFERASE (METHYLASE) | |
| M. thermoresistible (build 8) | TH_2193 | - | 1e-10 | 36.28% (113) | CONSERVED HYPOTHETICAL PROTEIN |
| M. thermoresistible (build 8) | TH_2189 | - | 7e-09 | 33.33% (108) | CONSERVED HYPOTHETICAL PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2976 | - | 7e-80 | 59.35% (246) | methyltransferase (methylase) |
| M. gilvum PYR-GCK | Mflv_4269 | - | 8e-09 | 30.71% (140) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv2952 | - | 7e-80 | 59.35% (246) | methyltransferase (methylase) |
| M. leprae Br4923 | MLBr_00130 | - | 9e-77 | 54.90% (255) | hypothetical protein MLBr_00130 |
| M. abscessus ATCC 19977 | MAB_4103c | - | 1e-101 | 68.80% (266) | methyltransferase |
| M. marinum M | MMAR_1766 | - | 2e-81 | 60.57% (246) | methyltransferase |
| M. avium 104 | MAV_3903 | - | 1e-08 | 33.02% (106) | methyltransferase, UbiE/COQ5 family protein |
| M. smegmatis MC2 155 | MSMEG_0393 | - | 1e-106 | 68.91% (267) | Fmt protein |
| M. ulcerans Agy99 | MUL_2009 | - | 2e-77 | 62.78% (223) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_0109 | - | 2e-10 | 38.54% (96) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2976|M.bovis_AF2122/97 MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEE-D
Rv2952|M.tuberculosis_H37Rv MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEE-D
MLBr_00130|M.leprae_Br4923 MAFTRIHSFLASAGNTSMYKRVWRFWYPLMTHKLGTDEIMFINWAYEE-D
MMAR_1766|M.marinum_M MALSRTHRVVAGVAHTRVYKKIWKYWYPLMTRGLGADELVFINWAYEE-D
MUL_2009|M.ulcerans_Agy99 MALSRTHRVVAGVAHTRVYKKIWKYWYPLMTRGLGADELVFINWAYEE-D
TH_1636|M.thermoresistible__bu --VRESRDQVFRKLNEKLTQHGQKFIYSYASRRLDDDDVVFLNYGYEE-D
MSMEG_0393|M.smegmatis_MC2_155 ---MEARDRVAWRLNIKVAQQAQKLVYRYATRRLKDDDVVFLNYGYEE-D
MAB_4103c|M.abscessus_ATCC_199 --MQRSRDWVMFKLNAVFTQRVQKFIYRHATRKLETEDVVFLNYGYEE-E
Mflv_4269|M.gilvum_PYR-GCK MTETKEPGAYPDVAVPAPTPHATKEQVEAALHDTKLAQVLYHDWEAETYD
MAV_3903|M.avium_104 MTRSTD---------AVPTPHATAEQVEAARHDSKLAQVLYHDWEAETYD
Mvan_0109|M.vanbaalenii_PYR-1 MTHTVLRMTERLLIDPPEHPDTSKGYLDLLGDEPDSNRGAIQALWASR--
.
Mb2976|M.bovis_AF2122/97 PPMDLPLEA-SDEPNRAHINLYHRTATQVDLGGK-QVLEVSCGHGGGASY
Rv2952|M.tuberculosis_H37Rv PPMDLPLEA-SDEPNRAHINLYHRTATQVDLGGK-QVLEVSCGHGGGASY
MLBr_00130|M.leprae_Br4923 PPMALPLEA-SDEPNRAHINLYHRTATQVNLSGK-RILEVSCGHGGGASY
MMAR_1766|M.marinum_M PPMDLPLEA-TDEPDRCHINLYHRTATQADLSGK-RVLEVSCGHGGGASY
MUL_2009|M.ulcerans_Agy99 PPMDLPLEA-TDEPDRCHINLYHRTATQADLSGK-RVLEVSCGHGGGASY
TH_1636|M.thermoresistible__bu PPMGLPLSE-TDEPNRYSIQLYHRTAGQADLTGK-RVLEVGCGHGGGASY
MSMEG_0393|M.smegmatis_MC2_155 PPMGIPLSE-SDELNRYSIQLYHSTAAQADVEGK-RVLEVGCGHGGGASY
MAB_4103c|M.abscessus_ATCC_199 PAMGVPLSA-SDEPDRYSIQLYHSTATQADLGGQ-RVLEVGCGHGGGASY
Mflv_4269|M.gilvum_PYR-GCK DKWSISYDQRCVDYARGRFDAAVPEEVQRELPYD-RALELGCGTGFFLLN
MAV_3903|M.avium_104 EKWSISYDQRCIDYARGRFDAIVPEHVLRELPYD-RALELGCGTGFFLLN
Mvan_0109|M.vanbaalenii_PYR-1 --LGSMFYDNAQTLARRLMTAWQQPTEWLNVPVGGTALDVGSGPGNVTGA
* : :: *::..* *
Mb2976|M.bovis_AF2122/97 LTRTLHPA-SYTGLDLNQAGIKLCKKRHRLPGLDFVR--GDAENLPFDDE
Rv2952|M.tuberculosis_H37Rv LTRTLHPA-SYTGLDLNQAGIKLCKKRHRLPGLDFVR--GDAENLPFDDE
MLBr_00130|M.leprae_Br4923 LTRALHPA-SYTGLDLNPAGIKLCQKRHQLPGLEFVR--GDAENLPFDNE
MMAR_1766|M.marinum_M LTRTLGPA-SYTALDLNPAGIKFCQQRHHLPGLDFVQ--GDAEDLPFEDE
MUL_2009|M.ulcerans_Agy99 LTRTLGPA-SYTALDLNPAGIKFCQQRHHLPGLDFVQ--GDAEDLPFEDE
TH_1636|M.thermoresistible__bu LMRTLGPM-SYVGLDLNPAGIEFCRKKHRLPGLEFVV--GDAQDLPFGAE
MSMEG_0393|M.smegmatis_MC2_155 LARTFRPA-TYTGLDLNSDGINFCRRRHNIAGLEFVQ--GDAQDLPFPDK
MAB_4103c|M.abscessus_ATCC_199 LVRALQPA-SYTGLDLNPDGISFCRRRHDLPGLEFVQ--GDAEDLPFPDE
Mflv_4269|M.gilvum_PYR-GCK LIQAGVAR-RGSVTDLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYEDN
MAV_3903|M.avium_104 LIQSGVAR-RGSVTDLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYEDD
Mvan_0109|M.vanbaalenii_PYR-1 LGRAVGPGGLALGVDISEPMLARAVRAEAGPNVGFIR--ADAQHLPFRDE
* :: . *:. : . : .: : .**: :*: .
Mb2976|M.bovis_AF2122/97 SFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNN-------
Rv2952|M.tuberculosis_H37Rv SFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNN-------
MLBr_00130|M.leprae_Br4923 SFDVVINIEASHCYPHFPRFLAEVVRVLRPGGHLAYADLRPSN-------
MMAR_1766|M.marinum_M SFDVVLNVEASHCYPRFPVFLEEVKRVLRPGGYFAYADIRPCT-------
MUL_2009|M.ulcerans_Agy99 SFDVVLNVEASHCYPRFPVFLEEVKRVLRPGGYFAYADIRPCT-------
TH_1636|M.thermoresistible__bu SFDAVINIESSHLYPRFSRFLSEVARVLRPGGHFLYADARQPH-------
MSMEG_0393|M.smegmatis_MC2_155 NFDAVLNVESSHLYPRFDVFLTEVARVLRPGGYFLYTDARPRY-------
MAB_4103c|M.abscessus_ATCC_199 SFDAVINVESSHLYPHFPVFLTEVARVLRPGGNFLYTDARSVQ-------
Mflv_4269|M.gilvum_PYR-GCK TFDLVVGHAVLHHIPDVELSLREVVRVLKPGGRFVFAGEPTTVGNRYARE
MAV_3903|M.avium_104 TFDLVVGHAVLHHIPDVELSLREVIRVLRPGGRFVFAGEPTSAGDVYARE
Mvan_0109|M.vanbaalenii_PYR-1 SFDAVVSIAMLQLIPDPAVALAEMVRVLRPGRRMAVMVPTAGP-------
.** *:. : * * *: ***:** :
Mb2976|M.bovis_AF2122/97 -EIAAWEADLAATPLRQLS-QRQINAEVLRGIGNNSQKSRDLVDRHLPAF
Rv2952|M.tuberculosis_H37Rv -EIAAWEADLAATPLRQLS-QRQINAEVLRGIGNNSQKSRDLVDRHLPAF
MLBr_00130|M.leprae_Br4923 -KVGEWEVDFANSRLQQLS-QREINAEVLRGIASNSQKSRDLVDRHLPAF
MMAR_1766|M.marinum_M -EIAEWEAALAAAGLQQIS-HREINAEVLRGIDINTPKSRELVKRHLPIF
MUL_2009|M.ulcerans_Agy99 -EIAEWEAALAAAGLQQIS-HREINAEVLRGIDINTPKSRERVKRHLPIF
TH_1636|M.thermoresistible__bu -EFAEWEAALAAAPLDMVS-ARVINAEVVRGMEQILPVWEDVIERVAPAF
MSMEG_0393|M.smegmatis_MC2_155 -DIPEWERALADAPLQMLS-QRAINFEVVRGMEKNLDALESVVDRVAPAL
MAB_4103c|M.abscessus_ATCC_199 -DVAGWKVALANAPLRMVS-ERGINAEVRRGMEKNLARWRYVIDRATPAP
Mflv_4269|M.gilvum_PYR-GCK LSTLTWHAATNIMKLPMLSDWRRPQAELDESSRAAALEAVVDLHTFDPAD
MAV_3903|M.avium_104 LSTLTWRIATNVTKLPGLGSWRRPQAELDESSRAAALEAIVDLHTFTPGD
Mvan_0109|M.vanbaalenii_PYR-1 --AAGLLRYLPNAGAHAFG-----DDELGDTFESLGLAGVRINTVGTIQW
.. : *:
Mb2976|M.bovis_AF2122/97 LRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD---------------
Rv2952|M.tuberculosis_H37Rv LRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD---------------
MLBr_00130|M.leprae_Br4923 LRFAGREFIGVQGTQLSRYLEGGELSYRMYSFAKD---------------
MMAR_1766|M.marinum_M LRAAGRNYIGATGTPLYRLMQSGDISYRMYCFVKE---------------
MUL_2009|M.ulcerans_Agy99 LRAAGRNYIGATGTPPIPPDAKR---------------------------
TH_1636|M.thermoresistible__bu LRRRVREFAPAR-RAWEELRTEGSTEYRMYCFTKPPEHADIP--------
MSMEG_0393|M.smegmatis_MC2_155 LRDWIQKYGPAR-RAYEELR-ENTTEYRMYCFVKPAE-------------
MAB_4103c|M.abscessus_ATCC_199 LRGIVRRFAPAQ-RAYDDLRAGGSVEYRMYRFVKA---------------
Mflv_4269|M.gilvum_PYR-GCK LERMAANAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKFAF
MAV_3903|M.avium_104 LERMAANAGATEVRTVSEEFTAAMFGWPVRTFEASVPPGRLGWGWAKFAF
Mvan_0109|M.vanbaalenii_PYR-1 VRGRKS--------------------------------------------
:.
Mb2976|M.bovis_AF2122/97 ----------------------------------
Rv2952|M.tuberculosis_H37Rv ----------------------------------
MLBr_00130|M.leprae_Br4923 ----------------------------------
MMAR_1766|M.marinum_M ----------------------------------
MUL_2009|M.ulcerans_Agy99 ----------------------------------
TH_1636|M.thermoresistible__bu ----------------------------------
MSMEG_0393|M.smegmatis_MC2_155 ----------------------------------
MAB_4103c|M.abscessus_ATCC_199 ----------------------------------
Mflv_4269|M.gilvum_PYR-GCK GSWTTLSWVDANVWRRIVPKGWFYNVMVTGVKPS
MAV_3903|M.avium_104 NGWKTLSWVDANIWRRVVPKGWFYNVMVTGVKPT
Mvan_0109|M.vanbaalenii_PYR-1 ----------------------------------