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DTRQRIQEVARELFAEKGVVRTSLQDIADRLGITKPALYYHFRSREELIRSILQPLIDEGEAFVAEQERK RAADRASARELLEGYFDFHYRHRADLVLIVSELTTLVDLGLIDQLLAWRARLGALVFGRTPTLEQSTRAV IAFGGLQDCCLQFPDVPAEQLRTATVNGAMAALGL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5718 | - | - | 100% (176) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6537 | - | 4e-17 | 31.43% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0227 | - | 3e-12 | 37.36% (91) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 3e-09 | 31.48% (108) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0973 | - | 2e-17 | 34.97% (183) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 3e-09 | 31.48% (108) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-08 | 30.23% (86) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2677c | - | 1e-40 | 50.00% (172) | putative trancscriptional regulator,TetR |
| M. marinum M | MMAR_4674 | - | 3e-66 | 72.57% (175) | transcriptional regulator |
| M. avium 104 | MAV_0985 | - | 9e-60 | 71.15% (156) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2336 | - | 9e-18 | 44.55% (101) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0293 | - | 8e-65 | 72.00% (175) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0170 | - | 2e-16 | 36.18% (152) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4674|M.marinum_M --------------------------------MTKPRSDTRRRIQEVARE
MUL_0293|M.ulcerans_Agy99 -------------------------------MVTKPRSDTRRRIQEVARE
MAV_0985|M.avium_104 --------------------------------------------------
MSMEG_5718|M.smegmatis_MC2_155 -------------------------------------MDTRQRIQEVARE
MAB_2677c|M.abscessus_ATCC_199 -----------------------------MLSDAAVAPGTRERIQTVARD
Mflv_0973|M.gilvum_PYR-GCK --------------------------MSGDSTRAGGP--TRRRLIDVAIE
TH_2336|M.thermoresistible__bu ------------VSGVGKPISREAALLTSRASAGTGP--TRQRLIEVAIE
Mvan_0170|M.vanbaalenii_PYR-1 --------------------------MTTASSAQMPPQSARQRVLDVALA
Mb3587c|M.bovis_AF2122/97 -----------------------------MDRVAGQVNSRRGELLELAAA
Rv3557c|M.tuberculosis_H37Rv -----------------------------MDRVAGQVNSRRGELLELAAA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MMAR_4674|M.marinum_M LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
MUL_0293|M.ulcerans_Agy99 LFLRQGVRGTSLQDIADRLGITKPALYYHFASREDLVRSIVVPLIEEGER
MAV_0985|M.avium_104 ------MQRTSLQDIADRLGITKPALYYHFPSREDLVRSILVPLIEEGER
MSMEG_5718|M.smegmatis_MC2_155 LFAEKGVVRTSLQDIADRLGITKPALYYHFRSREELIRSILQPLIDEGEA
MAB_2677c|M.abscessus_ATCC_199 LFAERGLRNTSLQDIASRLKITKPALYYHFSSRDELVRSIVQPMVDDLQT
Mflv_0973|M.gilvum_PYR-GCK LFKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVAE
TH_2336|M.thermoresistible__bu LFKQHSVAGTSLQMISDALGLTKSAIYHHFRTRDELLTAVMEPLISEVAE
Mvan_0170|M.vanbaalenii_PYR-1 LFTRHGYAGTSLQMIADEMGVTKGSLYYHFRAREDLLRALVGPLIEQLRA
Mb3587c|M.bovis_AF2122/97 MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
Rv3557c|M.tuberculosis_H37Rv MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: : *:. : . :* ** :: :: :: :
MMAR_4674|M.marinum_M FVAERERL---ADGNVRGLLEGYFDFHYRHRQDLMLVVVELTLLSDLGLI
MUL_0293|M.ulcerans_Agy99 FVAERERL---ADGNVRGLLEGYFDFHYRHRQDLMLVVVELTLLSDLGLI
MAV_0985|M.avium_104 FVAEHESR---EHTEARELLEGYFDFHYRHRRDLVLLLTELSTLIDLDLI
MSMEG_5718|M.smegmatis_MC2_155 FVAEQERKRAADRASARELLEGYFDFHYRHRADLVLIVSELTTLVDLGLI
MAB_2677c|M.abscessus_ATCC_199 FLATNNAG------DRRQLLEDYFDVLWTHRVVLGIIVRDLAALGQLELG
Mflv_0973|M.gilvum_PYR-GCK IVDAAEEQRT-PHARADHMLVGYASIAARHRTLIPLLSGDPGVVALLRTR
TH_2336|M.thermoresistible__bu IVSAAEARRG-ARTRADHFLRGYAALAAAHREVISLLTGDPGVVALLRTR
Mvan_0170|M.vanbaalenii_PYR-1 IVEHAEAQRS-PSVRAEHVLTGYARLAAANRALVAVTSGDPSVVEVIHAD
Mb3587c|M.bovis_AF2122/97 RYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF
Rv3557c|M.tuberculosis_H37Rv RYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
. . : :
MMAR_4674|M.marinum_M DTVLAWRERLGRLVFGAAPT------LGQATRAVLAFGGLQDCC-MQFP-
MUL_0293|M.ulcerans_Agy99 DTVLARRERLGRLVFGAAPT------LGQATRAVLAFGGLQDCC-MQFP-
MAV_0985|M.avium_104 DTVLAWRERLARLVFGKRPT------LAQSTRAVVAFGGLQDCC-VQFP-
MSMEG_5718|M.smegmatis_MC2_155 DQLLAWRARLGALVFGRTPT------LEQSTRAVIAFGGLQDCC-LQFP-
MAB_2677c|M.abscessus_ATCC_199 EWMMGWRRRLIVLLAGGKPS------AAQMIQATVALGGLSDCT-IEYA-
Mflv_0973|M.gilvum_PYR-GCK SEWGDLVRRQLALFSEVEPG------LGGQVKAALAMSGIASAAGVDYGG
TH_2336|M.thermoresistible__bu PDWAEVVQRQMALLGDVQPG------PGGRVKAAVVMAGIAAAAGVDYG-
Mvan_0170|M.vanbaalenii_PYR-1 PDWADLIDRQIGLLAAVQPG------LAGRVRATIVMAGIAATAAPGVV-
Mb3587c|M.bovis_AF2122/97 SYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
Rv3557c|M.tuberculosis_H37Rv SYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSR----LDPHRARMVAVGLVGISVDCARYW
: :. :
MMAR_4674|M.marinum_M DEPYAQLRQYSVEAALAALGV------------
MUL_0293|M.ulcerans_Agy99 DEPYAQLRQYSVEAALAALGV------------
MAV_0985|M.avium_104 DAPQAELRDKSVAAALDALGERPRR--------
MSMEG_5718|M.smegmatis_MC2_155 DVPAEQLRTATVNGAMAALGL------------
MAB_2677c|M.abscessus_ATCC_199 DRPHRQVKKTAVAAAIAALES------------
Mflv_0973|M.gilvum_PYR-GCK DVDDDTLRDQLIAAGRRALGLRNSRTGAVTARR
TH_2336|M.thermoresistible__bu DLDEAALRDELLAAGRRTLGLR-----APHARG
Mvan_0170|M.vanbaalenii_PYR-1 EADEAELCRQLIDAGRRTLGLR-----APRA--
Mb3587c|M.bovis_AF2122/97 YRPGGPLTAQQVGQQYLAIVLGGITKEGV----
Rv3557c|M.tuberculosis_H37Rv YRPGGPLTAQQVGQQYLAIVLGGITKEGV----
MLBr_00815|M.leprae_Br4923 LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-
: :