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MKFGMALPQYGPALGSAKDLARFATRLEELGYDTLWAAERLVMPLKIHSDVPVGDDDTWASYLDMIGAFG DPFSLVAAAAAVTDRIRFNFGTLNAPLHQPIRLAQTLTTLDVLSDGRIDAGFGLSWVRDEYDVSGLDWSS RGRRLDDTLDFLRVWWTENPVEYASPFISLPPSRVDLRPAQAGGPPVYLGGSSNAALARVGRRAAGWIGF DQLPDDVMKSLWSTARRAAEEADRDPDALRKIVRVNGEPGESVSHIADRLARQVDEGADEVMVDLVFTYK TIDERLDAAERLMHRKTW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0196 | - | - | 100% (298) | putative dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3609 | - | 3e-45 | 36.27% (295) | hydride transferase 1 |
| M. smegmatis MC2 155 | MSMEG_4398 | - | 4e-30 | 31.54% (298) | hypothetical protein MSMEG_4398 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 3e-22 | 31.44% (194) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4839 | - | 7e-26 | 29.34% (259) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 3e-22 | 31.44% (194) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 3e-12 | 24.51% (253) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 1e-25 | 31.25% (240) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1377 | - | 9e-27 | 31.41% (277) | hypothetical protein MMAR_1377 |
| M. avium 104 | MAV_2935 | - | 8e-26 | 33.07% (257) | hypothetical protein MAV_2935 |
| M. thermoresistible (build 8) | TH_4081 | - | 1e-32 | 28.23% (294) | PUTATIVE putative hydride transferase 1 |
| M. ulcerans Agy99 | MUL_2792 | - | 3e-27 | 33.17% (208) | hypothetical protein MUL_2792 |
| M. vanbaalenii PYR-1 | Mvan_5819 | - | 8e-25 | 31.96% (219) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 -----MQFGVLTFVTDEG----IGPAELGAALEHRGFESLFLAEHTHIPV
Rv3079c|M.tuberculosis_H37Rv -----MQFGVLTFVTDEG----IGPAELGAALEHRGFESLFLAEHTHIPV
MUL_2792|M.ulcerans_Agy99 -----MKFGISTFVNDDS----IDPVSLARAIEERGFSSLVIAEHTHIPA
Mvan_5819|M.vanbaalenii_PYR-1 -----MKFGIATFVNDTT----IDPVALARAVEDRGFGSLAVAEHTHIPA
MAB_0366|M.abscessus_ATCC_1997 -MKIGVVAPVELGVTAEP----DKILEFARAAERLGFSEISVVEHAVVIG
MAV_2935|M.avium_104 ------MAPVADGVTADP----DWMVAFARHLEACGFESIVAVEHTVLLT
Mflv_4839|M.gilvum_PYR-GCK -----------------------MIDAVAASAERSGFETLWFGDQVVMAD
MMAR_1377|M.marinum_M MTSVQLSMGIPSFSAEPPP-SWEHLTDWAQLLEGCGFDRVLVSEHIAFGA
MSMEG_0196|M.smegmatis_MC2_155 -----MKFGMALPQYGPALGSAKDLARFATRLEELGYDTLWAAERLVMPL
TH_4081|M.thermoresistible__bu -----VKFGISLFPLRPR-----QMVDVAVAAERLGYDSVWLGEHVVTPI
MLBr_00131|M.leprae_Br4923 --MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALV
* ::
Mb3106c|M.bovis_AF2122/97 NTQSPYPG-------GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIA
Rv3079c|M.tuberculosis_H37Rv NTQSPYPG-------GGPIPEKYYRTLDPFVALAAAAATTQSLVLGTGIA
MUL_2792|M.ulcerans_Agy99 SRETPYPG-------GDELPGVYYRTLDPFVTLAAAAAVTSKIELFTGIA
Mvan_5819|M.vanbaalenii_PYR-1 SRESAYPL-------GGELPSIYYRTLDPFVTLAAAAAVTTSIELVTGIA
MAB_0366|M.abscessus_ATCC_1997 DTQSTYPYSPT----GQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVL
MAV_2935|M.avium_104 RYDSVYPYDSS----GRVGLAPDCPIPDPLDLLAFLAGHTTRLGLATGVL
Mflv_4839|M.gilvum_PYR-GCK EDGPHHPYRDD----GEIPASAQTDWLDPLIALSFAAAATNRIELATGVL
MMAR_1377|M.marinum_M HMDAYANPATGGTAGGRQPTGPDGHWLEPLTTLTYLAARTERIRLGTNIL
MSMEG_0196|M.smegmatis_MC2_155 KIHSDVPVGDD--DTWASYLDMIGAFGDPFSLVAAAAAVTDRIRFNFGTL
TH_4081|M.thermoresistible__bu HSDSTFPYAED---DAHAAFHGQLPFYDPFAALGYLAAQTSTLRLVLSIS
MLBr_00131|M.leprae_Br4923 PRSVATPKYLG---VAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVC
:* : *. . : .
Mb3106c|M.bovis_AF2122/97 LIPE--RDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVR
Rv3079c|M.tuberculosis_H37Rv LIPE--RDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVR
MUL_2792|M.ulcerans_Agy99 LLIQ--RDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRDHGTDPKTR
Mvan_5819|M.vanbaalenii_PYR-1 LLIQ--RDPIITAKEAASIDLISNGRFVFGVGAGWNLEELRHHGTDPKTR
MAB_0366|M.abscessus_ATCC_1997 VLPD--HHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRR
MAV_2935|M.avium_104 VLPN--HHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNR
Mflv_4839|M.gilvum_PYR-GCK VLPE--RNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASR
MMAR_1377|M.marinum_M LAAL--RPAAVLAKTLATMDVLSGGRIDIGVGVGWQREEYEAAGADFDRR
MSMEG_0196|M.smegmatis_MC2_155 NAPL--HQPIRLAQTLTTLDVLSDGRIDAGFGLSWVRDEYDVSGLDWSSR
TH_4081|M.thermoresistible__bu IVPV--HDPFHLARSVTTLDLFSEGRFWFGMGAGWLREEFEILQKPFDGR
MLBr_00131|M.leprae_Br4923 VTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGE-REGNEPYGVEWTKP
: . *: ::. .: *: * . :
Mb3106c|M.bovis_AF2122/97 GRVIDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVTKPYPPLY
Rv3079c|M.tuberculosis_H37Rv GRVIDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVTKPYPPLY
MUL_2792|M.ulcerans_Agy99 GALLDERIEAIKALWTD---EPAEYHGKYVDFPPSYSRPKPVRQPHPPIY
Mvan_5819|M.vanbaalenii_PYR-1 GALLDERIEAIKALWTA---EPAEYHGKYVDFDASYLRPKPVQKPHPPIL
MAB_0366|M.abscessus_ATCC_1997 GRAADEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPVRPQGVPLY
MAV_2935|M.avium_104 GRRADEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPVAAERFPVH
Mflv_4839|M.gilvum_PYR-GCK GARLAEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQG-RSIPVV
MMAR_1377|M.marinum_M GAVLDQALEVCQRLWRE---NEVSFESVGLNFERIHQMPKPTQPGGVPIW
MSMEG_0196|M.smegmatis_MC2_155 GRRLDDTLDFLRVWWTEN---PVEYASPFISLPPSRVDLRPAQAGGPPVY
TH_4081|M.thermoresistible__bu GRILDETIDIMNRLFTQ---DVTTYRGRHFTVPPVGLQPKPLTRPHPPYL
MLBr_00131|M.leprae_Br4923 VARFQEALATIRALWDSN-GELVSRESQFFPLHNALFDLPPYRGKWPEIW
: : : . . . *
Mb3106c|M.bovis_AF2122/97 VGGGP--ANFPRIARLNAGWIAISPSPQRLSGPLQRLRAMAGGDVP----
Rv3079c|M.tuberculosis_H37Rv VGGGP--ANFPRIARLNAGWIAISPSPQRLSGPLQRLRAMAGGDVP----
MUL_2792|M.ulcerans_Agy99 IGGNSD-ATVKRVVRHDAGWISNPLPVHQLTQRVDQLRSAAGHDVP----
Mvan_5819|M.vanbaalenii_PYR-1 IGGDSD-AAVKRIIRHEAGWISNPLPVDTLRRRVDQIRAGARHEVP----
MAB_0366|M.abscessus_ATCC_1997 IGGHSK-AAARRAGRLGSGFQPLGLVGDDLTAAVG-VMRAAAVDAG----
MAV_2935|M.avium_104 IGGHSR-AAARRAGRFGDGFQPLGVTGARLASLIG-LMRDEAVAAG----
Mflv_4839|M.gilvum_PYR-GCK LGGNSD-AALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCREFG----
MMAR_1377|M.marinum_M VSGTVNRAVARRLARFGAGWIPWGPDARDVAAGIARMRAAVAHAGGDP--
MSMEG_0196|M.smegmatis_MC2_155 LGGSSN-AALARVGRRAAGWIGFDQLPDDVMKSLWSTARRAAEEAD----
TH_4081|M.thermoresistible__bu FGGHSR-KALERAAARGQGWLSSGMSPERNAEAIAFLRRERRRLGVD---
MLBr_00131|M.leprae_Br4923 VAAHGP-RMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPM
... .:
Mb3106c|M.bovis_AF2122/97 --------------------------------------------------
Rv3079c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_2792|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5819|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0366|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2935|M.avium_104 --------------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_1377|M.marinum_M ------------------------------------------------NG
MSMEG_0196|M.smegmatis_MC2_155 ------------------------------------------------RD
TH_4081|M.thermoresistible__bu -------------------------------------------------D
MLBr_00131|M.leprae_Br4923 SITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMG
Mb3106c|M.bovis_AF2122/97 VTVCQWGEAAAKDLEGYRHLGVERVLLELPTEPRD------PTLRYLDK-
Rv3079c|M.tuberculosis_H37Rv VTVCQWGEAAAKDLEGYRHLGVERVLLELPTEPRD------PTLRYLDK-
MUL_2792|M.ulcerans_Agy99 LAMFGT-RNKPDYWRAAQDLGFGPAGAAAAHLPAGGVPAAARRIRCPGGS
Mvan_5819|M.vanbaalenii_PYR-1 LSMFGT-PVKPEYWQAAEDLGFGQLNLLLPTKPRD------ESLRLLDG-
MAB_0366|M.abscessus_ATCC_1997 RDPRGLDLVLGHGLHRVDQAALDQAAHAGAGRMLLSASRRATTLEAVLEE
MAV_2935|M.avium_104 RDPAALEVSLGHSVSKIDAERAARLADQGADRLVLAMPP-TSDIEQAKDM
Mflv_4839|M.gilvum_PYR-GCK RDP--TELKLSVALHDPVPADAVRLADAGIDELVLVAGPPADPIAAEAWI
MMAR_1377|M.marinum_M FGVAGALRVKADADGRPDLADVAERAKTLRDAGVTELRMTHWPLAPESRE
MSMEG_0196|M.smegmatis_MC2_155 PDALRKIVRVNGEPGESVSHIADRLARQVDEGADEVMVDLVFTYKTIDER
TH_4081|M.thermoresistible__bu QPFECSTHLVGPVDRGLVDAYREAGVDRLVVRPWRKGGQAVEAITRLADD
MLBr_00131|M.leprae_Br4923 ADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEW
Mb3106c|M.bovis_AF2122/97 ------------LQAELARLA-----------------------------
Rv3079c|M.tuberculosis_H37Rv ------------LQAELARLA-----------------------------
MUL_2792|M.ulcerans_Agy99 IPPVEVPGGPSFLREPLARVSCASRRKIAPRFAAQCDFASARGGRLRVGS
Mvan_5819|M.vanbaalenii_PYR-1 ------------YAEQVARY------------------------------
MAB_0366|M.abscessus_ATCC_1997 MA----------GCATRLELG---GPR-----------------------
MAV_2935|M.avium_104 LS----------ACAQRLSLRPVSGP------------------------
Mflv_4839|M.gilvum_PYR-GCK AD----------LAGQWMRVRT----------------------------
MMAR_1377|M.marinum_M RD----------ISAVVEAVRAATGG------------------------
MSMEG_0196|M.smegmatis_MC2_155 LD----------AAERLMHRKTW---------------------------
TH_4081|M.thermoresistible__bu LG-----------VTRTDRVTDCSTHTI----------------------
MLBr_00131|M.leprae_Br4923 RDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL----------
Mb3106c|M.bovis_AF2122/97 ---
Rv3079c|M.tuberculosis_H37Rv ---
MUL_2792|M.ulcerans_Agy99 RPR
Mvan_5819|M.vanbaalenii_PYR-1 ---
MAB_0366|M.abscessus_ATCC_1997 ---
MAV_2935|M.avium_104 ---
Mflv_4839|M.gilvum_PYR-GCK ---
MMAR_1377|M.marinum_M ---
MSMEG_0196|M.smegmatis_MC2_155 ---
TH_4081|M.thermoresistible__bu ---
MLBr_00131|M.leprae_Br4923 ---