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VAPVADGVTADPDWMVAFARHLEACGFESIVAVEHTVLLTRYDSVYPYDSSGRVGLAPDCPIPDPLDLLA FLAGHTTRLGLATGVLVLPNHHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNRGRRADE QLAVLRALWAHRPDGASFHGEFFTFDNVMCYPKPVAAERFPVHIGGHSRAAARRAGRFGDGFQPLGVTGA RLASLIGLMRDEAVAAGRDPAALEVSLGHSVSKIDAERAARLADQGADRLVLAMPPTSDIEQAKDMLSAC AQRLSLRPVSGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2935 | - | - | 100% (292) | hypothetical protein MAV_2935 |
| M. avium 104 | MAV_2659 | - | 3e-30 | 35.06% (231) | hypothetical protein MAV_2659 |
| M. avium 104 | MAV_3045 | - | 7e-30 | 37.56% (197) | hypothetical protein MAV_3045 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 8e-29 | 34.80% (273) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_4839 | - | 4e-38 | 38.82% (255) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 8e-29 | 34.80% (273) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 3e-11 | 26.47% (204) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 3e-83 | 53.82% (288) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1586 | - | 3e-47 | 39.50% (281) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 2e-44 | 37.77% (278) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_4081 | - | 6e-32 | 34.13% (252) | PUTATIVE putative hydride transferase 1 |
| M. ulcerans Agy99 | MUL_3448 | - | 3e-47 | 39.50% (281) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3368 | - | 3e-31 | 35.09% (265) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 ---------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHIPV
Rv3079c|M.tuberculosis_H37Rv ---------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHTHIPV
MAV_2935|M.avium_104 ----------MAPVADGVTADPDWMVAFARHLEACGFESIVAVEHTVLLT
MAB_0366|M.abscessus_ATCC_1997 -----MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVVIG
MMAR_1586|M.marinum_M ------MQLGLHALGIGAGADRSMIDAVACAADDAGFATLWAGEHVVMVD
MUL_3448|M.ulcerans_Agy99 ------MQLGLHALEIGAGADRSMIDAVACAADDAGFATLWAGEHVVMVD
MSMEG_2811|M.smegmatis_MC2_155 ------MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVMVD
Mflv_4839|M.gilvum_PYR-GCK -----------------------MIDAVAASAERSGFETLWFGDQVVMAD
TH_4081|M.thermoresistible__bu ----------VKFGISLFPLRPRQMVDVAVAAERLGYDSVWLGEHVVTPI
Mvan_3368|M.vanbaalenii_PYR-1 MSTPVVVQTPAMASPWEGGADIEDVARIAEVADSLGFDYLTCSEHVAVPV
MLBr_00131|M.leprae_Br4923 --MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALV
* ::
Mb3106c|M.bovis_AF2122/97 NTQSPYPG---GGPIPEK-YYRTLDPFVALAAAAATT--QSLVLGTGIAL
Rv3079c|M.tuberculosis_H37Rv NTQSPYPG---GGPIPEK-YYRTLDPFVALAAAAATT--QSLVLGTGIAL
MAV_2935|M.avium_104 RYDSVYPYDSSGRVGLAP-DCPIPDPLDLLAFLAGHT--TRLGLATGVLV
MAB_0366|M.abscessus_ATCC_1997 DTQSTYPYSPTGQSHLPD-DIDIPDPLELLSFVAAAT--TTLGLSTGVLV
MMAR_1586|M.marinum_M RHTSRYPYSEDGVIAIPP-QADWLDPMIALSFAAAAS--SRITVATGVLL
MUL_3448|M.ulcerans_Agy99 RHTSRYPYSEDGVIAIPP-QADWLDPMIALSFAAASS--SRITVATGVLL
MSMEG_2811|M.smegmatis_MC2_155 RPRSRYPYSADGRIAVAA-DADWLDPMIALSFAAAAT--STIRIATGVLL
Mflv_4839|M.gilvum_PYR-GCK EDGPHHPYRDDGEIPASA-QTDWLDPLIALSFAAAAT--NRIELATGVLV
TH_4081|M.thermoresistible__bu HSDSTFPYAEDDAHAAFHGQLPFYDPFAALGYLAAQT--STLRLVLSISI
Mvan_3368|M.vanbaalenii_PYR-1 DEAG-----------LRG--AVYWDPLATLGFLAART--SRIRLATSVLV
MLBr_00131|M.leprae_Br4923 PRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTD
:* *. *. . : : :
Mb3106c|M.bovis_AF2122/97 IPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRV
Rv3079c|M.tuberculosis_H37Rv IPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRV
MAV_2935|M.avium_104 LPNHHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNRGRR
MAB_0366|M.abscessus_ATCC_1997 LPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRA
MMAR_1586|M.marinum_M LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRAGR
MUL_3448|M.ulcerans_Agy99 LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGR
MSMEG_2811|M.smegmatis_MC2_155 LPEHNPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRGAR
Mflv_4839|M.gilvum_PYR-GCK LPERNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRGAR
TH_4081|M.thermoresistible__bu VPVHDPFHLARSVTTLDLFSEGRFWFGMGAGWLREEFEILQKPFDGRGRI
Mvan_3368|M.vanbaalenii_PYR-1 LGYHHPLEIAKRYGTLDRVSGGRLVLGVGVGSLRAEFEMLSAPWEDRGVR
MLBr_00131|M.leprae_Br4923 AGRRNPAVTAQAAATLHLLTRGKAMLGIGVGE-REGNEPYGVEWTKPVAR
:.* *: ::. .: *: : * *
Mb3106c|M.bovis_AF2122/97 IDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
Rv3079c|M.tuberculosis_H37Rv IDERLRAIIEIWTQ---EQAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGG
MAV_2935|M.avium_104 ADEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPVAAERFPVHIGG
MAB_0366|M.abscessus_ATCC_1997 ADEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPVRPQGVPLYIGG
MMAR_1586|M.marinum_M TAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPVRDRRVPVMVGG
MUL_3448|M.ulcerans_Agy99 TAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPVRDRRVPVMVGG
MSMEG_2811|M.smegmatis_MC2_155 TAEYVEAMRTLWRQ---DVADFTGEFAAFDAVRLHPKPSAG-SIPIIVGG
Mflv_4839|M.gilvum_PYR-GCK LAEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQGR-SIPVVLGG
TH_4081|M.thermoresistible__bu LDETIDIMNRLFTQ---DVTTYRGRHFTVPPVGLQPKPLTRPHPPYLFGG
Mvan_3368|M.vanbaalenii_PYR-1 ADDAIRALRSSLSVS---APSYHGEFHRYQAMMVEPHAVQP-RVPIWVGG
MLBr_00131|M.leprae_Br4923 FQEALATIRALWDSN-GELVSRESQFFPLHNALFDLPPYRGKWPEIWVAA
: : : . . . ...
Mb3106c|M.bovis_AF2122/97 -GPANFPRIARLNAGWIAISPSP----QRLSGPLQRLRAMAGGDVP----
Rv3079c|M.tuberculosis_H37Rv -GPANFPRIARLNAGWIAISPSP----QRLSGPLQRLRAMAGGDVP----
MAV_2935|M.avium_104 HSRAAARRAGRFGDGFQPLGVTG-ARLASLIGLMRDEAVAAGRDPAAL--
MAB_0366|M.abscessus_ATCC_1997 HSKAAARRAGRLGSGFQPLGLVG-DDLTAAVGVMRAAAVDAGRDPRGL--
MMAR_1586|M.marinum_M NSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGRNRD----
MUL_3448|M.ulcerans_Agy99 NSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGRNRD----
MSMEG_2811|M.smegmatis_MC2_155 NGDRALARVASWGDGWYGFNLDGVAAVGERMDMLRRLCARAGRDVD----
Mflv_4839|M.gilvum_PYR-GCK NSDAALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCREFGRDPT----
TH_4081|M.thermoresistible__bu HSRKALERAAARGQGWLSSGMSP-ERNAEAIAFLRRERRRLGVDDQP---
Mvan_3368|M.vanbaalenii_PYR-1 RTARSLRRAVGLADGWMPFGLTP----ARIAEMLAAVDIPDDFDIVLA--
MLBr_00131|M.leprae_Br4923 HGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITP
.: : . :
Mb3106c|M.bovis_AF2122/97 ---------------------------VTVCQWGEAAAKDLEGYRHLGVE
Rv3079c|M.tuberculosis_H37Rv ---------------------------VTVCQWGEAAAKDLEGYRHLGVE
MAV_2935|M.avium_104 -------------------------EVSLGHSVSKIDAERAARLADQGAD
MAB_0366|M.abscessus_ATCC_1997 -------------------------DLVLGHGLHRVDQAALDQAAHAGAG
MMAR_1586|M.marinum_M -------------------------ELRLSVALRCPQPCDVDALAELGID
MUL_3448|M.ulcerans_Agy99 -------------------------ELRLSVALRCPQPCDVDALAELGID
MSMEG_2811|M.smegmatis_MC2_155 -------------------------DLHCAVALQAPAVGDIPALVDLGVD
Mflv_4839|M.gilvum_PYR-GCK -------------------------ELKLSVALHDPVPADAVRLADAGID
TH_4081|M.thermoresistible__bu -------------------------FECSTHLVGPVDRGLVDAYREAGVD
Mvan_3368|M.vanbaalenii_PYR-1 -------------------------VGPLDPRARDECLNRLRALRDVGAT
MLBr_00131|M.leprae_Br4923 AAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFA
.
Mb3106c|M.bovis_AF2122/97 R-VLLELPTEPRDPTLRYLDKLQAELARLA--------------------
Rv3079c|M.tuberculosis_H37Rv R-VLLELPTEPRDPTLRYLDKLQAELARLA--------------------
MAV_2935|M.avium_104 RLVLAMPP-TSDIEQAKDMLSACAQRLSLRPVSGP---------------
MAB_0366|M.abscessus_ATCC_1997 RMLLSASRRATTLEAVLEEMAGCATRLELG---GPR--------------
MMAR_1586|M.marinum_M ELVLVETPPEAADAAQNWVSALAERWLSTVWVR-----------------
MUL_3448|M.ulcerans_Agy99 ELVLVETPPEAADAAQNWVSALAERWLSTVWVR-----------------
MSMEG_2811|M.smegmatis_MC2_155 ELVIVESPPQDPDVAADWVDALADRWITCI--------------------
Mflv_4839|M.gilvum_PYR-GCK ELVLVAGPPADPIAAEAWIADLAGQWMRVRT-------------------
TH_4081|M.thermoresistible__bu RLVVRPWRKGGQAVEAITRLADDLGVTRTDRVTDCSTHTI----------
Mvan_3368|M.vanbaalenii_PYR-1 AVTCSLSASSAEHYCDQLASLRDLVDEL----------------------
MLBr_00131|M.leprae_Br4923 GVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHG
Mb3106c|M.bovis_AF2122/97 ------------------------------------
Rv3079c|M.tuberculosis_H37Rv ------------------------------------
MAV_2935|M.avium_104 ------------------------------------
MAB_0366|M.abscessus_ATCC_1997 ------------------------------------
MMAR_1586|M.marinum_M ------------------------------------
MUL_3448|M.ulcerans_Agy99 ------------------------------------
MSMEG_2811|M.smegmatis_MC2_155 ------------------------------------
Mflv_4839|M.gilvum_PYR-GCK ------------------------------------
TH_4081|M.thermoresistible__bu ------------------------------------
Mvan_3368|M.vanbaalenii_PYR-1 ------------------------------------
MLBr_00131|M.leprae_Br4923 LKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL