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KFGIATFVNDTTIDPVALARAVEDRGFGSLAVAEHTHIPASRESAYPLGGELPSIYYRTLDPFVTLAAAA AVTTSIELVTGIALLIQRDPIITAKEAASIDLISNGRFVFGVGAGWNLEELRHHGTDPKTRGALLDERIE AIKALWTAEPAEYHGKYVDFDASYLRPKPVQKPHPPILIGGDSDAAVKRIIRHEAGWISNPLPVDTLRRR VDQIRAGARHEVPLSMFGTPVKPEYWQAAEDLGFGQLNLLLPTKPRDESLRLLDGYAEQVARY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5819 | - | - | 100% (274) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 5e-45 | 38.87% (283) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 4e-31 | 37.38% (206) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 3e-72 | 51.27% (275) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_1017 | - | 1e-137 | 85.40% (274) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 3e-72 | 51.27% (275) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 9e-05 | 21.90% (210) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1059c | - | 6e-46 | 38.52% (283) | hypothetical protein MAB_1059c |
| M. marinum M | MMAR_3559 | - | 1e-129 | 80.66% (274) | hypothetical protein MMAR_3559 |
| M. avium 104 | MAV_1077 | - | 2e-46 | 39.56% (273) | hypothetical protein MAV_1077 |
| M. smegmatis MC2 155 | MSMEG_1996 | - | 1e-123 | 77.37% (274) | N5,N10- methylenetetrahydromethanopterin reductase-related |
| M. thermoresistible (build 8) | TH_2750 | - | 1e-127 | 78.10% (274) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2792 | - | 1e-116 | 80.08% (246) | hypothetical protein MUL_2792 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 -----------MQFGVLTFVTDEGIGPAELGAALEHR----GFESLFLAE
Rv3079c|M.tuberculosis_H37Rv -----------MQFGVLTFVTDEGIGPAELGAALEHR----GFESLFLAE
Mvan_5819|M.vanbaalenii_PYR-1 -----------MKFGIATFVNDTTIDPVALARAVEDR----GFGSLAVAE
Mflv_1017|M.gilvum_PYR-GCK -----------MKFGISTFPNEDTIDPVSLARAVEER----GFAALAVAE
TH_2750|M.thermoresistible__bu -----------MRFGISTFVNDDTIDPVSLATAIEER----GFDALTVAE
MMAR_3559|M.marinum_M -----------MKFGISTFVNDDSIDPVSLARAIEER----GFSSLVIAE
MUL_2792|M.ulcerans_Agy99 -----------MKFGISTFVNDDSIDPVSLARAIEER----GFSSLVIAE
MSMEG_1996|M.smegmatis_MC2_155 MHTVINSQGTGMKIGISTFVNDDTIDAVTLARAIEER----GFHSLVIAE
MAB_1059c|M.abscessus_ATCC_199 -----------MDYGLVLFTSDRGISPAIAAKAAEDG----GFSTFYVPE
MAV_1077|M.avium_104 ----------------MLFTSDRGISPAAAAKLADDH----GFATFYVPE
MLBr_00131|M.leprae_Br4923 --------MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGD
. : . . * : : :
Mb3106c|M.bovis_AF2122/97 HTHIPVNTQSPYP---GGGPIP-EKYYRTLDPFVALA--AAAATTQSLVL
Rv3079c|M.tuberculosis_H37Rv HTHIPVNTQSPYP---GGGPIP-EKYYRTLDPFVALA--AAAATTQSLVL
Mvan_5819|M.vanbaalenii_PYR-1 HTHIPASRESAYP---LGGELP-SIYYRTLDPFVTLA--AAAAVTTSIEL
Mflv_1017|M.gilvum_PYR-GCK HTHIPASRESAYP---LGGELP-KIYYRTLDPFVTLA--AAAAVTSEIEL
TH_2750|M.thermoresistible__bu HTHIPASRESPYP---EGGELP-SVYYRTLDPFVTLA--AAAAVTSRIQL
MMAR_3559|M.marinum_M HTHIPASRETPYP---GGGELP-GVYYRTLDPFVTLA--AAAAVTSKIEL
MUL_2792|M.ulcerans_Agy99 HTHIPASRETPYP---GGDELP-GVYYRTLDPFVTLA--AAAAVTSKIEL
MSMEG_1996|M.smegmatis_MC2_155 HSHIPASRESAYP---GGDELP-QKYYRTLDPFVTLA--AAAAVTTKIEL
MAB_1059c|M.abscessus_ATCC_199 HTHIPVKREAAHPG-TGGAELPDDRYMRTLDPWVSLG--AACAVTSKIRL
MAV_1077|M.avium_104 HTHIPIKREAAHPT-TGDASLPDDRYMRTLDPWVSLG--AACAVTSRVRL
MLBr_00131|M.leprae_Br4923 HLNALVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRL
* : . . * . :*:. *. ** : *
Mb3106c|M.bovis_AF2122/97 GTGIALIPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDP
Rv3079c|M.tuberculosis_H37Rv GTGIALIPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDP
Mvan_5819|M.vanbaalenii_PYR-1 VTGIALLIQRDPIITAKEAASIDLISNGRFVFGVGAGWNLEELRHHGTDP
Mflv_1017|M.gilvum_PYR-GCK ITGIALLIQRDPIITAKEAASIDVISGGRFVFGVGAGWNIEELRHHGTDP
TH_2750|M.thermoresistible__bu ITGIALLIQRDPIITAKEAASIDLISDGRFVFGVGAGWNLEEMRHHGTDP
MMAR_3559|M.marinum_M FTGIALLIQRDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRDHGTDP
MUL_2792|M.ulcerans_Agy99 FTGIALLIQRDPITTAKEAASIDLISGGRFVFGVGAGWNIEELRDHGTDP
MSMEG_1996|M.smegmatis_MC2_155 FTGVALLIQRDVIHTAKEAASVDLISNGRFVFGVGAGWNLEEMRNHGTDP
MAB_1059c|M.abscessus_ATCC_199 ATAVAIPVEHDPITLAKSIATLDHMSGGRVTVGVGYGWNTDELADHHVPA
MAV_1077|M.avium_104 STAVALPVEHDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHGVPA
MLBr_00131|M.leprae_Br4923 GVCVTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGE-REGNEPYGVEW
. :: .:: *: *::. :: *: .*:* * : : .
Mb3106c|M.bovis_AF2122/97 AVRGRVIDERLRAIIEIWTQ--EQAEFHGTYVDFDPIYCWPKPVTKPYPP
Rv3079c|M.tuberculosis_H37Rv AVRGRVIDERLRAIIEIWTQ--EQAEFHGTYVDFDPIYCWPKPVTKPYPP
Mvan_5819|M.vanbaalenii_PYR-1 KTRGALLDERIEAIKALWTA--EPAEYHGKYVDFDASYLRPKPVQKPHPP
Mflv_1017|M.gilvum_PYR-GCK KTRGALLDERIEAIKVLWTQ--EPAEYHGRFVDFDASYQRPKPVRKPHPP
TH_2750|M.thermoresistible__bu RTRGALLDERIEAVKALWTD--EPAEYHGRFVDFGPSYLRPKPVQKPHPP
MMAR_3559|M.marinum_M KTRGALLDERIEAIKALWTD--EPAEYHGKYVDFPPSYSRPKPVRQPHPP
MUL_2792|M.ulcerans_Agy99 KTRGALLDERIEAIKALWTD--EPAEYHGKYVDFPPSYSRPKPVRQPHPP
MSMEG_1996|M.smegmatis_MC2_155 KTRGRLLDEQIEAIKALWTQ--EPAEYHGKYVDIESSYMRPKPVQKPHPP
MAB_1059c|M.abscessus_ATCC_199 GRRRTMLREYIEAMRRLWEE--EEASYSGEFVNFGPSWAWPKTVQKHVPV
MAV_1077|M.avium_104 GRRRTMLREYLEAMRALWTQ--EEAAYDGEFVKFGPSWAWPKPVQPHIPV
MLBr_00131|M.leprae_Br4923 TKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPE
: * : :: :* * . . :. : . *
Mb3106c|M.bovis_AF2122/97 LYVGGGP-ANFPRIARLNAGWIAIS--PSPQR--LSGPLQRLRAMAGGD-
Rv3079c|M.tuberculosis_H37Rv LYVGGGP-ANFPRIARLNAGWIAIS--PSPQR--LSGPLQRLRAMAGGD-
Mvan_5819|M.vanbaalenii_PYR-1 ILIGGDSDAAVKRIIRHEAGWISNP--LPVDT--LRRRVDQIRAGARHE-
Mflv_1017|M.gilvum_PYR-GCK ILIGGDSDATVRRIIRHGAGWIANP--LPIDH--LSRRIEQIREGAGGD-
TH_2750|M.thermoresistible__bu IVVGGNSDATVRRIIRHGAGWMSNP--HPPEM--LKRRVQQIRDGAGHD-
MMAR_3559|M.marinum_M IYIGGNSDATVKRVVRHDAGWISNP--LPVRQ--LTQRVDQLRGAAGHD-
MUL_2792|M.ulcerans_Agy99 IYIGGNSDATVKRVVRHDAGWISNP--LPVHQ--LTQRVDQLRSAAGHD-
MSMEG_1996|M.smegmatis_MC2_155 IYIGGASEATVKRVIRHDAGWISNP--LPVDF--LSKFVTQMRDGLGHE-
MAB_1059c|M.abscessus_ATCC_199 IVGAGGTEKNFTWIAKNADGWMSTPRDEDIAG--KIVALKEAWKAAGRDG
MAV_1077|M.avium_104 LVGAAGNEKNFKWIARSADGWITTPRDFDIDE--PVKLLQDTWAAAGRDG
MLBr_00131|M.leprae_Br4923 IWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDP
: .. . : .*:. : :
Mb3106c|M.bovis_AF2122/97 VPVTVCQWG-----EAAAKDLEGYRHLGVE---RVLLELPTE--------
Rv3079c|M.tuberculosis_H37Rv VPVTVCQWG-----EAAAKDLEGYRHLGVE---RVLLELPTE--------
Mvan_5819|M.vanbaalenii_PYR-1 VPLSMFGT------PVKPEYWQAAEDLGFG---QLNLLLPTK--------
Mflv_1017|M.gilvum_PYR-GCK VPLCQFGT------PVKPEYWQAAEELGFG---QLNLLLPTK--------
TH_2750|M.thermoresistible__bu VLLTTFGT------PVDPGYWEVLEELGYQ---QANLLLPTR--------
MMAR_3559|M.marinum_M VPLAMFGT------PNKPDYWRAAQDLGFG---QLALLLPT---------
MUL_2792|M.ulcerans_Agy99 VPLAMFGT------RNKPDYWRAAQDLGFGPAGAAAAHLPAGGVPAAARR
MSMEG_1996|M.smegmatis_MC2_155 VPLAQFGT------PADPEYWGAVEELGFG---QIALLLPT---------
MAB_1059c|M.abscessus_ATCC_199 DPLIYVLAG-----KPDPEQLAAWRELGVT---EAIFGMPDR--------
MAV_1077|M.avium_104 APQIVALDF-----KPDAEKLARWAELGVT---EVLFGLPDK--------
MLBr_00131|M.leprae_Br4923 MSITPAAVRGIITGRTRDDVDEALDSVLVR---MIALGVPGEAWARHGVE
: :*
Mb3106c|M.bovis_AF2122/97 ---PRD---------------PTLRYLDKLQAELARLA------------
Rv3079c|M.tuberculosis_H37Rv ---PRD---------------PTLRYLDKLQAELARLA------------
Mvan_5819|M.vanbaalenii_PYR-1 ---PRD---------------ESLRLLDGYAEQVARY-------------
Mflv_1017|M.gilvum_PYR-GCK ---SRD---------------VSLRLLDDYAEQVARYIG-----------
TH_2750|M.thermoresistible__bu ---PRD---------------ESLRMLDQFAERVAGYRG-----------
MMAR_3559|M.marinum_M --CPRD---------------ESLRLLDEYAALVAQYHR-----------
MUL_2792|M.ulcerans_Agy99 IRCPGGSI-------PPVEVPGGPSFLREPLARVSCASRRKIAPRFAAQC
MSMEG_1996|M.smegmatis_MC2_155 --LPTD---------------ESLRMLDDYATAVEKYRG-----------
MAB_1059c|M.abscessus_ATCC_199 ---SEE---------------EVRAYIDRLSGKLAAFA------------
MAV_1077|M.avium_104 ---SED---------------EVAAYVERLAGKLAALV------------
MLBr_00131|M.leprae_Br4923 HPMGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQ
:
Mb3106c|M.bovis_AF2122/97 --------------------------------------------
Rv3079c|M.tuberculosis_H37Rv --------------------------------------------
Mvan_5819|M.vanbaalenii_PYR-1 --------------------------------------------
Mflv_1017|M.gilvum_PYR-GCK --------------------------------------------
TH_2750|M.thermoresistible__bu --------------------------------------------
MMAR_3559|M.marinum_M --------------------------------------------
MUL_2792|M.ulcerans_Agy99 DFASARGGRLRVGSRPR---------------------------
MSMEG_1996|M.smegmatis_MC2_155 --------------------------------------------
MAB_1059c|M.abscessus_ATCC_199 --------------------------------------------
MAV_1077|M.avium_104 --------------------------------------------
MLBr_00131|M.leprae_Br4923 VAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL