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IDAVAASAERSGFETLWFGDQVVMADEDGPHHPYRDDGEIPASAQTDWLDPLIALSFAAAATNRIELATG VLVLPERNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRGARLAEYVGAMRTLWRDDDA SFAGRYVAFDGVRANPKPQGRSIPVVLGGNSDAALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCREF GRDPTELKLSVALHDPVPADAVRLADAGIDELVLVAGPPADPIAAEAWIADLAGQWMRVRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4839 | - | - | 100% (272) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_4097 | - | 3e-31 | 34.73% (262) | luciferase family protein |
| M. gilvum PYR-GCK | Mflv_1590 | - | 3e-31 | 42.17% (166) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3099c | - | 5e-33 | 62.75% (102) | hypothetical protein Mb3099c |
| M. tuberculosis H37Rv | Rv3072c | - | 5e-33 | 62.75% (102) | hypothetical protein Rv3072c |
| M. leprae Br4923 | MLBr_00348 | - | 9e-11 | 28.86% (149) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 6e-33 | 34.85% (264) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1586 | - | 1e-88 | 60.59% (269) | oxidoreductase |
| M. avium 104 | MAV_2935 | - | 4e-38 | 38.82% (255) | hypothetical protein MAV_2935 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 2e-88 | 58.21% (268) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_2146 | - | 3e-34 | 36.11% (252) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3448 | - | 3e-88 | 60.22% (269) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 7e-31 | 35.00% (240) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3099c|M.bovis_AF2122/97 MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM
Rv3072c|M.tuberculosis_H37Rv MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM
MMAR_1586|M.marinum_M --------MQLGLHALGIGAGADRSMIDAVACAADDAGFATLWAGEHVVM
MUL_3448|M.ulcerans_Agy99 --------MQLGLHALEIGAGADRSMIDAVACAADDAGFATLWAGEHVVM
MSMEG_2811|M.smegmatis_MC2_155 --------MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVM
Mflv_4839|M.gilvum_PYR-GCK -------------------------MIDAVAASAERSGFETLWFGDQVVM
MAB_0366|M.abscessus_ATCC_1997 -------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVV
MAV_2935|M.avium_104 ------------MAPVADGVTADPDWMVAFARHLEACGFESIVAVEHTVL
TH_2146|M.thermoresistible__bu ---------------MRFAFTYPMDSHPYHPDLATGAAVARVAATAETAG
Mvan_2248|M.vanbaalenii_PYR-1 ---------------MQFAITHPMHSHPYNPELVTGTGIAQVAQAAEKAG
MLBr_00348|M.leprae_Br4923 ---------------------------MVERANAMKLGLQLGYWAAQPPG
.. .
Mb3099c|M.bovis_AF2122/97 VDRPASRYPYSRDGVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLLL
Rv3072c|M.tuberculosis_H37Rv VDRPASRYPYSRDGVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLLL
MMAR_1586|M.marinum_M VDRHTSRYPYSEDGVIAIPPQADWLDPMIALSFAAAASSRITVATGVLLL
MUL_3448|M.ulcerans_Agy99 VDRHTSRYPYSEDGVIAIPPQADWLDPMIALSFAAASSSRITVATGVLLL
MSMEG_2811|M.smegmatis_MC2_155 VDRPRSRYPYSADGRIAVAADADWLDPMIALSFAAAATSTIRIATGVLLL
Mflv_4839|M.gilvum_PYR-GCK ADEDGPHHPYRDDGEIPASAQTDWLDPLIALSFAAAATNRIELATGVLVL
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLVL
MAV_2935|M.avium_104 LTRYDSVYPYDSSGRVGLAPDCPIPDPLDLLAFLAGHTTRLGLATGVLVL
TH_2146|M.thermoresistible__bu FSGFGFTDHPAPTQKWLDHGGHDTLDPFVAMGFAAAHTTTLRLIPHIVVL
Mvan_2248|M.vanbaalenii_PYR-1 FGGFGFTDHPAPTQRWLEAGGHDALDPFVAMGFAAAHTSTLRLIPNIVVL
MLBr_00348|M.leprae_Br4923 NAAELVAAAEGAGFDAVFTGEAWGSDAYTPLAWWGSSTQRVRLGTSVVQL
*. :.: .. : : : . :: *
Mb3099c|M.bovis_AF2122/97 PEHNPVIVAKEAASLDRLSGRRLTLGVAS---------------------
Rv3072c|M.tuberculosis_H37Rv PEHNPVIVAKEAASLDRLSGRRLTLGVAS---------------------
MMAR_1586|M.marinum_M PEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRAGRT
MUL_3448|M.ulcerans_Agy99 PEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGRT
MSMEG_2811|M.smegmatis_MC2_155 PEHNPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRGART
Mflv_4839|M.gilvum_PYR-GCK PERNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRGARL
MAB_0366|M.abscessus_ATCC_1997 PDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRAA
MAV_2935|M.avium_104 PNHHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNRGRRA
TH_2146|M.thermoresistible__bu PYRNPFVVAKAGASVDLLSGGRFTLGVGVGYLKREFAALGVDFEERAALF
Mvan_2248|M.vanbaalenii_PYR-1 PYRNPFVVAKAGATLDLISEGRFTLAVGVGYLKREFTALGVDFDERAELF
MLBr_00348|M.leprae_Br4923 SARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRT
. : * * ::* :: * : .
Mb3099c|M.bovis_AF2122/97 --------------------------------------------------
Rv3072c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1586|M.marinum_M AEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPV----------RD
MUL_3448|M.ulcerans_Agy99 AEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPV----------RD
MSMEG_2811|M.smegmatis_MC2_155 AEYVEAMRTLWRQ---DVADFTGEFAAFDAVRLHPKPS----------AG
Mflv_4839|M.gilvum_PYR-GCK AEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQ----------GR
MAB_0366|M.abscessus_ATCC_1997 DEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPV----------RP
MAV_2935|M.avium_104 DEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPV----------AA
TH_2146|M.thermoresistible__bu EEALEVIRAIWTT---DNVSYTGRHFTADGITAHPHPV----------TK
Mvan_2248|M.vanbaalenii_PYR-1 EESLQVIRDAWTT---DDITFEGKHFSAKGITAHPRPV----------ST
MLBr_00348|M.leprae_Br4923 REYIDIVRQVWAR--EAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLR
Mb3099c|M.bovis_AF2122/97 --------------------------------------------------
Rv3072c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1586|M.marinum_M RRVPVMVGGNSDAALRRVAAWADGWYGF----------------------
MUL_3448|M.ulcerans_Agy99 RRVPVMVGGNSDAALRRVAAWADGWYGF----------------------
MSMEG_2811|M.smegmatis_MC2_155 -SIPIIVGGNGDRALARVASWGDGWYGF----------------------
Mflv_4839|M.gilvum_PYR-GCK -SIPVVLGGNSDAALRRVAEWGDGWYGF----------------------
MAB_0366|M.abscessus_ATCC_1997 QGVPLYIGGHSKAAARRAGRLGSGFQPL----------------------
MAV_2935|M.avium_104 ERFPVHIGGHSRAAARRAGRFGDGFQPL----------------------
TH_2146|M.thermoresistible__bu PHPPIWIGGNTGAARQRVADHGAGWCPFPAPAVLAQTA------------
Mvan_2248|M.vanbaalenii_PYR-1 PHPPIWVGGNTSAARARVARYAQGWCPFRAPAVLAQTA------------
MLBr_00348|M.leprae_Br4923 ADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTG
Mb3099c|M.bovis_AF2122/97 --------------------DGP-----RRSSTRSECHSSGAQS------
Rv3072c|M.tuberculosis_H37Rv --------------------DGP-----RRSSTRSECHSSGAQS------
MMAR_1586|M.marinum_M ------------------NLDGVGAVRERVGTLDRLCAESGRNRDELRLS
MUL_3448|M.ulcerans_Agy99 ------------------NLDGVGAVRERVGTLDRLCAESGRNRDELRLS
MSMEG_2811|M.smegmatis_MC2_155 ------------------NLDGVAAVGERMDMLRRLCARAGRDVDDLHCA
Mflv_4839|M.gilvum_PYR-GCK ------------------DLADVEEAAFRASKLRSMCREFGRDPTELKLS
MAB_0366|M.abscessus_ATCC_1997 ------------------GLVGDD-LTAAVGVMRAAAVDAGRDPRGLDLV
MAV_2935|M.avium_104 ------------------GVTGAR-LASLIGLMRDEAVAAGRDPAALEVS
TH_2146|M.thermoresistible__bu ---------------RTAAMDSAEALAAGITDLHRRLEATGRDPADVDVV
Mvan_2248|M.vanbaalenii_PYR-1 ---------------RTAALETVEHLKAGIDDLRRRLEGTGRDPFDIDIT
MLBr_00348|M.leprae_Br4923 ARRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHAD
* :
Mb3099c|M.bovis_AF2122/97 ------------------------------------------APPNTSLQ
Rv3072c|M.tuberculosis_H37Rv ------------------------------------------APPNTSLQ
MMAR_1586|M.marinum_M V----------------ALRCPQPCDVDALAELGIDELVLVETPPEAADA
MUL_3448|M.ulcerans_Agy99 V----------------ALRCPQPCDVDALAELGIDELVLVETPPEAADA
MSMEG_2811|M.smegmatis_MC2_155 V----------------ALQAPAVGDIPALVDLGVDELVIVESPPQDPDV
Mflv_4839|M.gilvum_PYR-GCK V----------------ALHDPVPADAVRLADAGIDELVLVAGPPADPIA
MAB_0366|M.abscessus_ATCC_1997 LGH--------------GLHRVDQAALDQAAHAGAGRMLLSASRRATTLE
MAV_2935|M.avium_104 LGH--------------SVSKIDAERAARLADQGADRLVLAMPP-TSDIE
TH_2146|M.thermoresistible__bu FS---------------NLTGGTPGRADFNADAYLDGVAKLGALGVTWLQ
Mvan_2248|M.vanbaalenii_PYR-1 FT---------------NDAGGSPGAADFNADEFLSGAAELERAGVTWIQ
MLBr_00348|M.leprae_Br4923 VYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVCKQ
Mb3099c|M.bovis_AF2122/97 CAHYGATTSHRSTATVGS-----------
Rv3072c|M.tuberculosis_H37Rv CAHYGATTSHRSTATVGS-----------
MMAR_1586|M.marinum_M AQNWVSALAERWLSTVWVR----------
MUL_3448|M.ulcerans_Agy99 AQNWVSALAERWLSTVWVR----------
MSMEG_2811|M.smegmatis_MC2_155 AADWVDALADRWITCI-------------
Mflv_4839|M.gilvum_PYR-GCK AEAWIADLAGQWMRVRT------------
MAB_0366|M.abscessus_ATCC_1997 AVLEEMAGCATRLELG---GPR-------
MAV_2935|M.avium_104 QAKDMLSACAQRLSLRPVSGP--------
TH_2146|M.thermoresistible__bu VPIPGDSLNHALEAIEAFGSEVIGKL---
Mvan_2248|M.vanbaalenii_PYR-1 VTVPGDSLAHTLEAIEEFGGSVIGRP---
MLBr_00348|M.leprae_Br4923 IAAWSAAGVTMMMVSASSVEQVRDLAGLF