For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MQTCATQLARDIVDRYQSELPSIVPDPPAVADQLASVEASVRQIAECIDSGEGPRLLDLTPATAAIGRSG VQRNIALNDLFRSVRMAQERTWQWLFDRITASSAATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREA WLTGAAAARAAAVEDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEALTQLTRAI AAQSVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGIHLPQDVRVAIGEPGWGISGFRRTHVEASHAQ RFVSLLGDRAEVVTCYRNVAVAALAGTDRGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRSPAKA AQRLGVHPNTVSYRVHQAEELLGRTIDIGALDLSVALALLPAMRAMTQRSGGEL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4951 | - | - | 100% (404) | hypothetical protein MMAR_4951 |
| M. marinum M | MMAR_2601 | - | e-113 | 53.81% (407) | hypothetical protein MMAR_2601 |
| M. marinum M | MMAR_1603 | - | 2e-30 | 28.72% (397) | hypothetical protein MMAR_1603 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1464 | - | 2e-23 | 25.87% (402) | hypothetical protein Mb1464 |
| M. gilvum PYR-GCK | Mflv_4621 | - | 1e-29 | 30.09% (339) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1429 | - | 2e-23 | 25.87% (402) | hypothetical protein Rv1429 |
| M. leprae Br4923 | MLBr_01052 | - | 5e-22 | 26.36% (349) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 8e-27 | 29.22% (373) | hypothetical protein MAB_2657c |
| M. avium 104 | MAV_1330 | - | 7e-07 | 29.26% (188) | hypothetical protein MAV_1330 |
| M. smegmatis MC2 155 | MSMEG_6492 | - | 6e-08 | 26.10% (272) | GAF domain-containing protein |
| M. thermoresistible (build 8) | TH_2938 | - | 1e-33 | 32.09% (349) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0453 | - | 0.0 | 94.50% (382) | hypothetical protein MUL_0453 |
| M. vanbaalenii PYR-1 | Mvan_4527 | - | 3e-05 | 24.54% (273) | hypothetical protein Mvan_4527 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4951|M.marinum_M --------------------------------------------------
MUL_0453|M.ulcerans_Agy99 -----------------------------MRGRCAGSTTRLDFVDMKPRW
Mb1464|M.bovis_AF2122/97 --------------------------------------------------
Rv1429|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4621|M.gilvum_PYR-GCK --------------------------------------------------
TH_2938|M.thermoresistible__bu --------------------------------------------------
MLBr_01052|M.leprae_Br4923 --------------------------------------------------
MAB_2657c|M.abscessus_ATCC_199 ------------------------------------MNEGSERVHTQSMT
MAV_1330|M.avium_104 -------MAGVGLGQLLLALDATMVSLVDAPRGLDQPVASAALIDSDDVR
Mvan_4527|M.vanbaalenii_PYR-1 ---MVVTPAGLGLGQLLLALDRTMVTLVEAPRGLDMPVGSVALVDADDVR
MSMEG_6492|M.smegmatis_MC2_155 MTWLGALRRLSASATAEEDLSHVLAEIAETARSLLGFDFCGVLLPDEQSR
MMAR_4951|M.marinum_M ----------------------MQTCATQLARD------IVDRYQSEL--
MUL_0453|M.ulcerans_Agy99 PPFQEPSARRVWQQVLRPLAAEMQTCATQLARD------IVDRYQSEL--
Mb1464|M.bovis_AF2122/97 -------MAEAGGGPISVIARHMQLIRDDFISE------LFDKMKAEI--
Rv1429|M.tuberculosis_H37Rv -------MAEAGGGPISVIARHMQLIRDDFISE------LFDKMKAEI--
Mflv_4621|M.gilvum_PYR-GCK -MLDSSEVQDTPGHAVHHLFRDLGDLVRELPES------IHGLLIEQV--
TH_2938|M.thermoresistible__bu --------------------------VGYGPGS------RQG--------
MLBr_01052|M.leprae_Br4923 --MARQHPSPRVRELIREGARIALNPTQEWIDQ------LDRATFAAN--
MAB_2657c|M.abscessus_ATCC_199 PDQLWPDASEPVRRLIRELAEKMLARSGEVAGD------LTAASLEDPRY
MAV_1330|M.avium_104 LGLAAAAGSADVFFLLGVGDDEALRWIDTQARDRVPVAVFVKEPSDALVG
Mvan_4527|M.vanbaalenii_PYR-1 LGLAVGPGSVDLFFLLGVADVDALRWLEHHADR--PVAIFVKEPTAEAVA
MSMEG_6492|M.smegmatis_MC2_155 HLRVRGASGLSSDYVDRVNSDRPLVLHGGSPSS------RAFHTAEAVAI
MMAR_4951|M.marinum_M PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPRLLDLT---PATAAIG
MUL_0453|M.ulcerans_Agy99 PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPRLLDLT---PATAAIG
Mb1464|M.bovis_AF2122/97 RGLDYDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP---AAALAYA
Rv1429|M.tuberculosis_H37Rv RGLDYDARMADLWRASITENFVTAVHYLDRDTPQSLVEAP---AAALAYA
Mflv_4621|M.gilvum_PYR-GCK AELAADQQLKELLSDTVAANVDTWFSVVRHSIPFDRMESP---TAALEHA
TH_2938|M.thermoresistible__bu ---SGCRQLLELLRDSVEGNIDTIFSAIQHDIPIEEVAPP---TAALEYA
MLBr_01052|M.leprae_Br4923 PAIANDPVLAKVVRRASRAHLVHWATANLRDPGAPVPAHLG--PEPLTMA
MAB_2657c|M.abscessus_ATCC_199 RTIADDPVIAEVDARLTVSNLKHWLTSNISEPGHRVRPATG--SAMRTYA
MAV_1330|M.avium_104 TAVAAGSAVVAVDPRARWERLYQLVNHVLEHHGDRADAADDSGTDLFGLA
Mvan_4527|M.vanbaalenii_PYR-1 RAVALGAAVVAVDPRARWEHLYRLVNYALEHHGDRDDPSRDSGTDLFGLA
MSMEG_6492|M.smegmatis_MC2_155 RDVTAEPGFELWAGIANEQGYRSMIAVPLVARGEVLGTLNGYYGAVHTYT
MMAR_4951|M.marinum_M RSGVQRNI-----------------------ALNDLFRSVRMAQERTWQW
MUL_0453|M.ulcerans_Agy99 RSGVQRNI-----------------------ALNDLFRSVRMAQERTWQW
Mb1464|M.bovis_AF2122/97 RAAAQRDI-----------------------PLSGLVRAHRLGHARFLEV
Rv1429|M.tuberculosis_H37Rv RAAAQRDI-----------------------PLSGLVRAHRLGHARFLEV
Mflv_4621|M.gilvum_PYR-GCK RRMAQREV-----------------------PVNALLRAYRLGHQYGLNL
TH_2938|M.thermoresistible__bu RRLARHGV-----------------------EPHALLRAYRLGQQKLLDI
MLBr_01052|M.leprae_Br4923 RDLVRRGR-----------------------DVLALD-IYRVGQYTAWRR
MAB_2657c|M.abscessus_ATCC_199 RDVVLRGL-----------------------TTDDIQ-SWRAVQRVGWKW
MAV_1330|M.avium_104 QSLAERIHGMVSIENAQSQVLAYSASNDEADELRRLSILGRAGPPEHLEW
Mvan_4527|M.vanbaalenii_PYR-1 QSIADRTRGMICIEDADSRMLAYSASSEEADELRRLTILGRAGPPEHLEW
MSMEG_6492|M.smegmatis_MC2_155 RFEVERMTLLAN------HAAIAVSSARRLDELRALTASLRRQRDALTRS
: . : : *
MMAR_4951|M.marinum_M L-----FDRIT-ASSAATDHDRALDLATN---WLFGYVDVVLIRAERLYE
MUL_0453|M.ulcerans_Agy99 L-----FDRIT-ASSAATDHDRALDLATN---WLFGYVDVVLIRAERLYE
Mb1464|M.bovis_AF2122/97 A-----MQYVS--LLEPADRVSTIIELVN---RSARLVDLVADQLIVAYE
Rv1429|M.tuberculosis_H37Rv A-----MQYVS--LLEPADRVSTIIELVN---RSARLVDLVADQLIVAYE
Mflv_4621|M.gilvum_PYR-GCK I-----IAGLRSADLPPEEKLALIEHITR---VSFRYIDWMSEQVLETYQ
TH_2938|M.thermoresistible__bu V-----LHEIRSLDWEREVSLEFVVGVTN---ATFGYIDGISQRVVEVYQ
MLBr_01052|M.leprae_Br4923 W-----MEIAFTLTSDPQELREILNVSAQ---SINEYVAATLEAIATHMQ
MAB_2657c|M.abscessus_ATCC_199 W-----LAACFQVTDDKEQLCELIEVTSN---SLTTFVDDSIAELAEHVR
MAV_1330|M.avium_104 IGQWGIFDALRSGTQVVRVAERPELGLRP---RLAVGIHQPDPDARRPPV
Mvan_4527|M.vanbaalenii_PYR-1 IGQWGIFDALRAGPDVVRVAERPELGLRP---RLAVGIHLP-ADTRHAPR
MSMEG_6492|M.smegmatis_MC2_155 EQIHDRLLAVTLRSGGLDGIAAVLQGLIGRPILIDDIQHEVLACSVVTTD
:
MMAR_4951|M.marinum_M VEREAWLTGAAA--------------------------------------
MUL_0453|M.ulcerans_Agy99 VEREAWLTGAAA--------------------------------------
Mb1464|M.bovis_AF2122/97 HEHDRWLSRRSG--------------------------------------
Rv1429|M.tuberculosis_H37Rv HEHDRWLSRRSG--------------------------------------
Mflv_4621|M.gilvum_PYR-GCK TERAEWDERRRS--------------------------------------
TH_2938|M.thermoresistible__bu QERERWLENRNS--------------------------------------
MLBr_01052|M.leprae_Br4923 LERDELTRSTHA--------------------------------------
MAB_2657c|M.abscessus_ATCC_199 RVREELAGGSQL--------------------------------------
MAV_1330|M.avium_104 FAGTIWVQQGAQ--------------------------------------
Mvan_4527|M.vanbaalenii_PYR-1 FAGTIWLQQGSS--------------------------------------
MSMEG_6492|M.smegmatis_MC2_155 FPDTTWRAAAEAGTGSSPVPVGQFDGTTYLASAVHLGDEVAARIWFPETS
MMAR_4951|M.marinum_M -----ARAAAVEDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDA
MUL_0453|M.ulcerans_Agy99 -----ARAAAVEDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDA
Mb1464|M.bovis_AF2122/97 -----LQQQWVSELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPI
Rv1429|M.tuberculosis_H37Rv -----LQQQWVSELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPI
Mflv_4621|M.gilvum_PYR-GCK -----LRAQAIRDILNGRDVDLTEASSAMRYFLGATHVALMVWLDRDAGA
TH_2938|M.thermoresistible__bu -----LRAMRVRELLDGGEVDVDTASATVGYPLRRTHLAVCVWTP-DGSA
MLBr_01052|M.leprae_Br4923 -----ERLEVVDLILEGAPVTQERAEARLGYRLGLTHTAAVIWSDDLDGD
MAB_2657c|M.abscessus_ATCC_199 -----QRYATVELLLQGADIAPARAEAQLGYALTGSHIGAVVWVDSEK-E
MAV_1330|M.avium_104 -----PLADDAEQILRGAAVLAARIMARLAARPSTQARRLQQLLGVTDSE
Mvan_4527|M.vanbaalenii_PYR-1 -----ALADDAEEILRGGSVLAARIMSRLATAPSQHAARLQQLLGLTG--
MSMEG_6492|M.smegmatis_MC2_155 IDLDPIMVRAVEHASIVTALELLRCQTAAEVEQRLRGELLSDVLSSGAAL
MMAR_4951|M.marinum_M CAGPVTLTEA--------------------------------LTQLTRAI
MUL_0453|M.ulcerans_Agy99 CAGPVTLTEA--------------------------------LTQLTRAI
Mb1464|M.bovis_AF2122/97 GDVVAQFDQVRCLL----------------------------AGELGPEL
Rv1429|M.tuberculosis_H37Rv GDVVAQFDQVRCLL----------------------------AGELGPEL
Mflv_4621|M.gilvum_PYR-GCK DTDEFIAMER---F----------------------------MQHAVSAT
TH_2938|M.thermoresistible__bu GDNELDRLQR---Y----------------------------VRGLAEAL
MLBr_01052|M.leprae_Br4923 HGYLDQAAEA-----------------------------------FSHVV
MAB_2657c|M.abscessus_ATCC_199 IAALERASEQ-----------------------------------VMRAC
MAV_1330|M.avium_104 TLAPVDLTAIAAELGLAADGCAALVGWAAAEGASRHTRLTDVIALSASAF
Mvan_4527|M.vanbaalenii_PYR-1 -VDVDDVGALARELGIPEDARAAIVGFRGLG----TAVPADVIALSAGAF
MSMEG_6492|M.smegmatis_MC2_155 SDRLLDRAHRLGHDLTVPHIAIVGAFTGLDPVAERRAYERSLVLLAKESA
MMAR_4951|M.marinum_M AAQSVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGIHLPQDVRVAIG
MUL_0453|M.ulcerans_Agy99 AAQSVLAHPAGSKAIAGWLSRPQAFTAAELDAANICSGIHLPQDVRVAIG
Mb1464|M.bovis_AF2122/97 GPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFESAGIRARLACG
Rv1429|M.tuberculosis_H37Rv GPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFESAGIRARLACG
Mflv_4621|M.gilvum_PYR-GCK GAK-QSVYFSIDRLVGCAWMTVH--RPSDYLSQLRDFVRAQPDGPRLSVG
TH_2938|M.thermoresistible__bu GAPGDSLFIALDRLTGCGWIPLPGDAATGAVAGVRRYAAEHPDGPHLALG
MLBr_01052|M.leprae_Br4923 ESTQQLIVVAS---AATRWVWLADALALDVPEVQKALLNLS--KARVAIG
MAB_2657c|M.abscessus_ATCC_199 GADRRLTVVAG---TVALWLWIPAKTTPTVAVLMDSLGRRS--GVRVALG
MAV_1330|M.avium_104 RHDAHVAGHGSRTYVLLPQP-PNRSVSSWVRGTIAALRAELGVQLRAVIA
Mvan_4527|M.vanbaalenii_PYR-1 RADAQVAAAGDRVYVLLPKAGAAASLTSWVRGVVAALRRELGLEVRAVT-
MSMEG_6492|M.smegmatis_MC2_155 AHRPKPVVAMHAGTIVMLWPAQDAADAAGAGEVVRQAMRAASADRQATVA
:
MMAR_4951|M.marinum_M EPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN--VAVAALAGT
MUL_0453|M.ulcerans_Agy99 EPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN--VAVAALAGT
Mb1464|M.bovis_AF2122/97 RVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAPVALLAD
Rv1429|M.tuberculosis_H37Rv RVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD--VAPVALLAD
Mflv_4621|M.gilvum_PYR-GCK EPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVALASMLMT
TH_2938|M.thermoresistible__bu DPLPGLDGFRRSYRQALRTRAVAVAA-GASAPRVTAAADPGLSAAALLTG
MLBr_01052|M.leprae_Br4923 TSSAGIEGFRRSHLEALTAQR--TLARLKSHQQVAFFAD--VQLVSLITQ
MAB_2657c|M.abscessus_ATCC_199 RAATGMAGFRRTHMDAAAAQR--LLARLGSPLSVVRYED--VHLMDLLSA
MAV_1330|M.avium_104 APVPGLSGVAAARAEVDRVLDSAERHPLSFGQVTSLAEARTTVLLDEIVT
Mvan_4527|M.vanbaalenii_PYR-1 APLTGPAGAAGARADVDRVFDSAERHPGAIDLVTSLDEARTTVLLDEIVS
MSMEG_6492|M.smegmatis_MC2_155 VGPGDVASHRESYQTAKGALQ--VAIMSGRTAAVVGLDDLGIAGLLLRIN
. . : . .
MMAR_4951|M.marinum_M DRGHAVAFVRRVLG-PLAANDEGTYRIAATLAVYLEENRSPAKAAQRLGV
MUL_0453|M.ulcerans_Agy99 DRGHAVAFVRRVLG-PLAANDEGTYRIAATLAVYLEENRSPAKAAQRLGV
Mb1464|M.bovis_AF2122/97 DLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVATADAMIL
Rv1429|M.tuberculosis_H37Rv DLEELRRFVTDVLG-DLSVDDERNSWLRETLREFLLRNRSYVATADAMIL
Mflv_4621|M.gilvum_PYR-GCK DDATLKEWIHDVLG-PLAQNTASDQRLRDTLRVFLRAGSSFKAAANELQI
TH_2938|M.thermoresistible__bu DLAEARTWVQEVLG-PLSADTKNDARLRETLGVFLRHGSSYTAAADELNL
MLBr_01052|M.leprae_Br4923 NPEDAKEFITSTLG-DFES---ASPALQQTLLTFINEQCNASRAAKRLFT
MAB_2657c|M.abscessus_ATCC_199 DPASADQFVTDVLG-EFQS---ASPVLHQTVLTYVEEALNRTSTAERLYT
MAV_1330|M.avium_104 LVGRDERLVDPRIV-ALHD---REPVLAQTLRTYLDAFGDIAAAAHALRV
Mvan_4527|M.vanbaalenii_PYR-1 HVAAQPRLVDPRVR-RLRA---GDPLLAETLQAFLDGFGDIAAIAARLHV
MSMEG_6492|M.smegmatis_MC2_155 DPAALSTFARRTLAPILDYDHAHRTELLVTLRAYLECRQERSATATRLVI
: : : *: :: . * :
MMAR_4951|M.marinum_M HPNTVSYRVHQAEELLGRTIDIG--ALDLSVALALLPAMRAMTQRSGGEL
MUL_0453|M.ulcerans_Agy99 HP-------RAPALLISRLVSWG--IVD----------------------
Mb1464|M.bovis_AF2122/97 HRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAKQ--
Rv1429|M.tuberculosis_H37Rv HRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAKQ--
Mflv_4621|M.gilvum_PYR-GCK HANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLGEVALNPTQAL
TH_2938|M.thermoresistible__bu HFNTVKYRVQRAVERRGRPIVP--DRLDVELALLICQWFGAAVLRPQR--
MLBr_01052|M.leprae_Br4923 HRNTLLRRIESAEKLLPRPLDHT--SVHIAVALEALQWRGDQTNTSGPRA
MAB_2657c|M.abscessus_ATCC_199 HRNTIDRRLARVDELLPKPFARN--PIEVAAALTLLRVRAGR--------
MAV_1330|M.avium_104 HPNTVRYRVRRIEKLLSVSLADPEVRLLFALALRAAER------------
Mvan_4527|M.vanbaalenii_PYR-1 HPNTVRYRIRRVEKLLSTSLEDPDSRLVLALGLRATEPR-----------
MSMEG_6492|M.smegmatis_MC2_155 HPNTVAQRLRRIESLCSVTLTDPAVILQFSAALTVYDIAALD--------
* . .
MMAR_4951|M.marinum_M --------
MUL_0453|M.ulcerans_Agy99 --------
Mb1464|M.bovis_AF2122/97 --------
Rv1429|M.tuberculosis_H37Rv --------
Mflv_4621|M.gilvum_PYR-GCK GRS-----
TH_2938|M.thermoresistible__bu --------
MLBr_01052|M.leprae_Br4923 GRNDGVPA
MAB_2657c|M.abscessus_ATCC_199 --------
MAV_1330|M.avium_104 --------
Mvan_4527|M.vanbaalenii_PYR-1 --------
MSMEG_6492|M.smegmatis_MC2_155 --------