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M. ulcerans Agy99 MUL_0453 (-)

annotation: hypothetical protein MUL_0453
coordinates: 464190 - 465446
length: 418

RGRCAGSTTRLDFVDMKPRWPPFQEPSARRVWQQVLRPLAAEMQTCATQLARDIVDRYQSELPSIVPDPP
AVADQLASVEASVRQIAECIDSGEGPRLLDLTPATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDR
ITASSAATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAVEDILTEREDDAQRAS
TRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEALTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAA
ELDAANICSGIHLPQDVRVAIGEPGWGISGFRRTHVEASHAQRFVSLLGDRAEVVTCYRNVAVAALAGTD
RGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRSPAKAAQRLGVHPRAPALLISRLVSWGIVD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0453--100% (418)hypothetical protein MUL_0453
M. ulcerans Agy99MUL_3434-1e-2426.61% (387) hypothetical protein MUL_3434
M. ulcerans Agy99MUL_3452-4e-2426.14% (352) hypothetical protein MUL_3452

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1464-6e-1824.60% (374) hypothetical protein Mb1464
M. gilvum PYR-GCKMflv_4621-5e-2227.44% (317) hypothetical protein Mflv_4621
M. tuberculosis H37RvRv1429-6e-1824.60% (374) hypothetical protein Rv1429
M. leprae Br4923MLBr_01052-1e-1424.59% (305) hypothetical protein MLBr_01052
M. abscessus ATCC 19977MAB_2657c-5e-2428.61% (388) hypothetical protein MAB_2657c
M. marinum MMMAR_4951-0.094.50% (382) hypothetical protein MMAR_4951
M. avium 104-----
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_2938-7e-2729.27% (328) PUTATIVE putative conserved hypothetical protein
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


MUL_0453|M.ulcerans_Agy99           MRGRCAGSTTRLDFVDMKPRWPPFQEPSARRVWQQVLRPLAAEMQTCATQ
MMAR_4951|M.marinum_M               -------------------------------------------MQTCATQ
Mb1464|M.bovis_AF2122/97            ----------------------------MAEAGGGPISVIARHMQLIRDD
Rv1429|M.tuberculosis_H37Rv         ----------------------------MAEAGGGPISVIARHMQLIRDD
Mflv_4621|M.gilvum_PYR-GCK          ----------------------MLDSSEVQDTPGHAVHHLFRDLGDLVRE
TH_2938|M.thermoresistible__bu      -----------------------------------------------VGY
MLBr_01052|M.leprae_Br4923          -----------------------MARQHPSPRVRELIREGARIALNPTQE
MAB_2657c|M.abscessus_ATCC_199      -------MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGE
                                                                                      

MUL_0453|M.ulcerans_Agy99           LARDIVDRYQSEL--PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPR
MMAR_4951|M.marinum_M               LARDIVDRYQSEL--PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPR
Mb1464|M.bovis_AF2122/97            FISELFDKMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQS
Rv1429|M.tuberculosis_H37Rv         FISELFDKMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQS
Mflv_4621|M.gilvum_PYR-GCK          LPESIHGLLIEQV--AELAADQQLKELLSDTVAANVDTWFSVVRHSIPFD
TH_2938|M.thermoresistible__bu      GPGSRQG-----------SGCRQLLELLRDSVEGNIDTIFSAIQHDIPIE
MLBr_01052|M.leprae_Br4923          WIDQLDRATFAAN--PAIANDPVLAKVVRRASRAHLVHWATANLRDPGAP
MAB_2657c|M.abscessus_ATCC_199      VAGDLTAASLEDPRYRTIADDPVIAEVDARLTVSNLKHWLTSNISEPGHR
                                       .                               .              

MUL_0453|M.ulcerans_Agy99           LLDLT-PATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDRIT-ASS
MMAR_4951|M.marinum_M               LLDLT-PATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDRIT-ASS
Mb1464|M.bovis_AF2122/97            LVEAP-AAALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LL
Rv1429|M.tuberculosis_H37Rv         LVEAP-AAALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LL
Mflv_4621|M.gilvum_PYR-GCK          RMESP-TAALEHARRMAQREVPVNALLRAYRLGHQYGLNLIIAGLRSADL
TH_2938|M.thermoresistible__bu      EVAPP-TAALEYARRLARHGVEPHALLRAYRLGQQKLLDIVLHEIRSLDW
MLBr_01052|M.leprae_Br4923          VPAHLGPEPLTMARDLVRRGRDVLALD-IYRVGQYTAWRRWMEIAFTLTS
MAB_2657c|M.abscessus_ATCC_199      VRPATGSAMRTYARDVVLRGLTTDDIQ-SWRAVQRVGWKWWLAACFQVTD
                                          .     .*  . :      :    *  :       :        

MUL_0453|M.ulcerans_Agy99           AATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAV
MMAR_4951|M.marinum_M               AATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAV
Mb1464|M.bovis_AF2122/97            EPADRVSTIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWV
Rv1429|M.tuberculosis_H37Rv         EPADRVSTIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWV
Mflv_4621|M.gilvum_PYR-GCK          PPEEKLALIEHITRVSFRYIDWMSEQVLETYQTERAEWDERRRSLRAQAI
TH_2938|M.thermoresistible__bu      EREVSLEFVVGVTNATFGYIDGISQRVVEVYQQERERWLENRNSLRAMRV
MLBr_01052|M.leprae_Br4923          DPQELREILNVSAQSINEYVAATLEAIATHMQLERDELTRSTHAERLEVV
MAB_2657c|M.abscessus_ATCC_199      DKEQLCELIEVTSNSLTTFVDDSIAELAEHVRRVREELAGGSQLQRYATV
                                            :    .     :           .  :          :   :

MUL_0453|M.ulcerans_Agy99           EDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEA-
MMAR_4951|M.marinum_M               EDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEA-
Mb1464|M.bovis_AF2122/97            SELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR
Rv1429|M.tuberculosis_H37Rv         SELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR
Mflv_4621|M.gilvum_PYR-GCK          RDILNGRDVDLTEASSAMRYFLGATHVALMVWLDRDAGADTDEFIAMER-
TH_2938|M.thermoresistible__bu      RELLDGGEVDVDTASATVGYPLRRTHLAVCVWTP-DGSAGDNELDRLQR-
MLBr_01052|M.leprae_Br4923          DLILEGAPVTQERAEARLGYRLGLTHTAAVIWSDDLDGDHGYLDQAAEA-
MAB_2657c|M.abscessus_ATCC_199      ELLLQGADIAPARAEAQLGYALTGSHIGAVVWVDSEK-EIAALERASEQ-
                                      :*         *.  : * :   * .  :*               :  

MUL_0453|M.ulcerans_Agy99           ---LTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAAELDAANICSGI
MMAR_4951|M.marinum_M               ---LTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGI
Mb1464|M.bovis_AF2122/97            CLLAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFE
Rv1429|M.tuberculosis_H37Rv         CLLAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFE
Mflv_4621|M.gilvum_PYR-GCK          --FMQHAVSATGAK-QSVYFSIDRLVGCAWMTVH--RPSDYLSQLRDFVR
TH_2938|M.thermoresistible__bu      --YVRGLAEALGAPGDSLFIALDRLTGCGWIPLPGDAATGAVAGVRRYAA
MLBr_01052|M.leprae_Br4923          ------FSHVVESTQQLIVVAS---AATRWVWLADALALDVPEVQKALLN
MAB_2657c|M.abscessus_ATCC_199      ------VMRACGADRRLTVVAG---TVALWLWIPAKTTPTVAVLMDSLGR
                                                .       .                             

MUL_0453|M.ulcerans_Agy99           HLPQDVRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN
MMAR_4951|M.marinum_M               HLPQDVRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN
Mb1464|M.bovis_AF2122/97            SAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD
Rv1429|M.tuberculosis_H37Rv         SAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD
Mflv_4621|M.gilvum_PYR-GCK          AQPDGPRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARD
TH_2938|M.thermoresistible__bu      EHPDGPHLALGDPLPGLDGFRRSYRQALRTRAVAVAA-GASAPRVTAAAD
MLBr_01052|M.leprae_Br4923          LS--KARVAIGTSSAGIEGFRRSHLEALTAQR--TLARLKSHQQVAFFAD
MAB_2657c|M.abscessus_ATCC_199      RS--GVRVALGRAATGMAGFRRTHMDAAAAQR--LLARLGSPLSVVRYED
                                          ::: *    *: *** :  :*  .:             :    :

MUL_0453|M.ulcerans_Agy99           --VAVAALAGTDRGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRS
MMAR_4951|M.marinum_M               --VAVAALAGTDRGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRS
Mb1464|M.bovis_AF2122/97            --VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRS
Rv1429|M.tuberculosis_H37Rv         --VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRS
Mflv_4621|M.gilvum_PYR-GCK          PGVALASMLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVFLRAGSS
TH_2938|M.thermoresistible__bu      PGLSAAALLTGDLAEARTWVQEVLGPLSADTKNDARLRETLGVFLRHGSS
MLBr_01052|M.leprae_Br4923          --VQLVSLITQNPEDAKEFITSTLGDFES---ASPALQQTLLTFINEQCN
MAB_2657c|M.abscessus_ATCC_199      --VHLMDLLSADPASADQFVTDVLGEFQS---ASPVLHQTVLTYVEEALN
                                      :    :   :      ::  .** :         :  *:  ::    .

MUL_0453|M.ulcerans_Agy99           PAKAAQRLGVHP-------RAPALLISRLVSWG--IVD------------
MMAR_4951|M.marinum_M               PAKAAQRLGVHPNTVSYRVHQAEELLGRTIDIG--ALDLSVALALLPAMR
Mb1464|M.bovis_AF2122/97            YVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMA
Rv1429|M.tuberculosis_H37Rv         YVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMA
Mflv_4621|M.gilvum_PYR-GCK          FKAAANELQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLG
TH_2938|M.thermoresistible__bu      YTAAADELNLHFNTVKYRVQRAVERRGRPIVP--DRLDVELALLICQWFG
MLBr_01052|M.leprae_Br4923          ASRAAKRLFTHRNTLLRRIESAEKLLPRPLDHT--SVHIAVALEALQWRG
MAB_2657c|M.abscessus_ATCC_199      RTSTAERLYTHRNTIDRRLARVDELLPKPFARN--PIEVAAALTLLRVRA
                                       :*. :  *                : .      .             

MUL_0453|M.ulcerans_Agy99           ------------------
MMAR_4951|M.marinum_M               AMTQRSGGEL--------
Mb1464|M.bovis_AF2122/97            PAVLRAKQ----------
Rv1429|M.tuberculosis_H37Rv         PAVLRAKQ----------
Mflv_4621|M.gilvum_PYR-GCK          EVALNPTQALGRS-----
TH_2938|M.thermoresistible__bu      AAVLRPQR----------
MLBr_01052|M.leprae_Br4923          DQTNTSGPRAGRNDGVPA
MAB_2657c|M.abscessus_ATCC_199      GR----------------