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RGRCAGSTTRLDFVDMKPRWPPFQEPSARRVWQQVLRPLAAEMQTCATQLARDIVDRYQSELPSIVPDPP AVADQLASVEASVRQIAECIDSGEGPRLLDLTPATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDR ITASSAATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAVEDILTEREDDAQRAS TRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEALTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAA ELDAANICSGIHLPQDVRVAIGEPGWGISGFRRTHVEASHAQRFVSLLGDRAEVVTCYRNVAVAALAGTD RGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRSPAKAAQRLGVHPRAPALLISRLVSWGIVD*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0453 | - | - | 100% (418) | hypothetical protein MUL_0453 |
M. ulcerans Agy99 | MUL_3434 | - | 1e-24 | 26.61% (387) | hypothetical protein MUL_3434 |
M. ulcerans Agy99 | MUL_3452 | - | 4e-24 | 26.14% (352) | hypothetical protein MUL_3452 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1464 | - | 6e-18 | 24.60% (374) | hypothetical protein Mb1464 |
M. gilvum PYR-GCK | Mflv_4621 | - | 5e-22 | 27.44% (317) | hypothetical protein Mflv_4621 |
M. tuberculosis H37Rv | Rv1429 | - | 6e-18 | 24.60% (374) | hypothetical protein Rv1429 |
M. leprae Br4923 | MLBr_01052 | - | 1e-14 | 24.59% (305) | hypothetical protein MLBr_01052 |
M. abscessus ATCC 19977 | MAB_2657c | - | 5e-24 | 28.61% (388) | hypothetical protein MAB_2657c |
M. marinum M | MMAR_4951 | - | 0.0 | 94.50% (382) | hypothetical protein MMAR_4951 |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | - | - | - | - | - |
M. thermoresistible (build 8) | TH_2938 | - | 7e-27 | 29.27% (328) | PUTATIVE putative conserved hypothetical protein |
M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0453|M.ulcerans_Agy99 MRGRCAGSTTRLDFVDMKPRWPPFQEPSARRVWQQVLRPLAAEMQTCATQ MMAR_4951|M.marinum_M -------------------------------------------MQTCATQ Mb1464|M.bovis_AF2122/97 ----------------------------MAEAGGGPISVIARHMQLIRDD Rv1429|M.tuberculosis_H37Rv ----------------------------MAEAGGGPISVIARHMQLIRDD Mflv_4621|M.gilvum_PYR-GCK ----------------------MLDSSEVQDTPGHAVHHLFRDLGDLVRE TH_2938|M.thermoresistible__bu -----------------------------------------------VGY MLBr_01052|M.leprae_Br4923 -----------------------MARQHPSPRVRELIREGARIALNPTQE MAB_2657c|M.abscessus_ATCC_199 -------MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLARSGE MUL_0453|M.ulcerans_Agy99 LARDIVDRYQSEL--PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPR MMAR_4951|M.marinum_M LARDIVDRYQSEL--PSIVPDPPAVADQLASVEASVRQIAECIDSGEGPR Mb1464|M.bovis_AF2122/97 FISELFDKMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQS Rv1429|M.tuberculosis_H37Rv FISELFDKMKAEI--RGLDYDARMADLWRASITENFVTAVHYLDRDTPQS Mflv_4621|M.gilvum_PYR-GCK LPESIHGLLIEQV--AELAADQQLKELLSDTVAANVDTWFSVVRHSIPFD TH_2938|M.thermoresistible__bu GPGSRQG-----------SGCRQLLELLRDSVEGNIDTIFSAIQHDIPIE MLBr_01052|M.leprae_Br4923 WIDQLDRATFAAN--PAIANDPVLAKVVRRASRAHLVHWATANLRDPGAP MAB_2657c|M.abscessus_ATCC_199 VAGDLTAASLEDPRYRTIADDPVIAEVDARLTVSNLKHWLTSNISEPGHR . . MUL_0453|M.ulcerans_Agy99 LLDLT-PATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDRIT-ASS MMAR_4951|M.marinum_M LLDLT-PATAAIGRSGVQRNIALNDLFRSVRMAQERTWQWLFDRIT-ASS Mb1464|M.bovis_AF2122/97 LVEAP-AAALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LL Rv1429|M.tuberculosis_H37Rv LVEAP-AAALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVS--LL Mflv_4621|M.gilvum_PYR-GCK RMESP-TAALEHARRMAQREVPVNALLRAYRLGHQYGLNLIIAGLRSADL TH_2938|M.thermoresistible__bu EVAPP-TAALEYARRLARHGVEPHALLRAYRLGQQKLLDIVLHEIRSLDW MLBr_01052|M.leprae_Br4923 VPAHLGPEPLTMARDLVRRGRDVLALD-IYRVGQYTAWRRWMEIAFTLTS MAB_2657c|M.abscessus_ATCC_199 VRPATGSAMRTYARDVVLRGLTTDDIQ-SWRAVQRVGWKWWLAACFQVTD . .* . : : * : : MUL_0453|M.ulcerans_Agy99 AATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAV MMAR_4951|M.marinum_M AATDHDRALDLATNWLFGYVDVVLIRAERLYEVEREAWLTGAAAARAAAV Mb1464|M.bovis_AF2122/97 EPADRVSTIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWV Rv1429|M.tuberculosis_H37Rv EPADRVSTIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWV Mflv_4621|M.gilvum_PYR-GCK PPEEKLALIEHITRVSFRYIDWMSEQVLETYQTERAEWDERRRSLRAQAI TH_2938|M.thermoresistible__bu EREVSLEFVVGVTNATFGYIDGISQRVVEVYQQERERWLENRNSLRAMRV MLBr_01052|M.leprae_Br4923 DPQELREILNVSAQSINEYVAATLEAIATHMQLERDELTRSTHAERLEVV MAB_2657c|M.abscessus_ATCC_199 DKEQLCELIEVTSNSLTTFVDDSIAELAEHVRRVREELAGGSQLQRYATV : . : . : : : MUL_0453|M.ulcerans_Agy99 EDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEA- MMAR_4951|M.marinum_M EDILTEREDDAQRASTRLRYDVNRHHVGVSVWRDVTQDACAGPVTLTEA- Mb1464|M.bovis_AF2122/97 SELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR Rv1429|M.tuberculosis_H37Rv SELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVR Mflv_4621|M.gilvum_PYR-GCK RDILNGRDVDLTEASSAMRYFLGATHVALMVWLDRDAGADTDEFIAMER- TH_2938|M.thermoresistible__bu RELLDGGEVDVDTASATVGYPLRRTHLAVCVWTP-DGSAGDNELDRLQR- MLBr_01052|M.leprae_Br4923 DLILEGAPVTQERAEARLGYRLGLTHTAAVIWSDDLDGDHGYLDQAAEA- MAB_2657c|M.abscessus_ATCC_199 ELLLQGADIAPARAEAQLGYALTGSHIGAVVWVDSEK-EIAALERASEQ- :* *. : * : * . :* : MUL_0453|M.ulcerans_Agy99 ---LTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAAELDAANICSGI MMAR_4951|M.marinum_M ---LTQLTRAIAAQSVLAHPAGSKAIAGWLSRPQAFTAAELDVANICSGI Mb1464|M.bovis_AF2122/97 CLLAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFE Rv1429|M.tuberculosis_H37Rv CLLAGELGPELGPVANSLMVPTDEREARLWFSPAP-TRAFAPSRIRAAFE Mflv_4621|M.gilvum_PYR-GCK --FMQHAVSATGAK-QSVYFSIDRLVGCAWMTVH--RPSDYLSQLRDFVR TH_2938|M.thermoresistible__bu --YVRGLAEALGAPGDSLFIALDRLTGCGWIPLPGDAATGAVAGVRRYAA MLBr_01052|M.leprae_Br4923 ------FSHVVESTQQLIVVAS---AATRWVWLADALALDVPEVQKALLN MAB_2657c|M.abscessus_ATCC_199 ------VMRACGADRRLTVVAG---TVALWLWIPAKTTPTVAVLMDSLGR . . MUL_0453|M.ulcerans_Agy99 HLPQDVRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN MMAR_4951|M.marinum_M HLPQDVRVAIGEPGWGISGFRRTHVEASHAQR-FVSLLGDRAEVVTCYRN Mb1464|M.bovis_AF2122/97 SAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD Rv1429|M.tuberculosis_H37Rv SAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDD Mflv_4621|M.gilvum_PYR-GCK AQPDGPRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARD TH_2938|M.thermoresistible__bu EHPDGPHLALGDPLPGLDGFRRSYRQALRTRAVAVAA-GASAPRVTAAAD MLBr_01052|M.leprae_Br4923 LS--KARVAIGTSSAGIEGFRRSHLEALTAQR--TLARLKSHQQVAFFAD MAB_2657c|M.abscessus_ATCC_199 RS--GVRVALGRAATGMAGFRRTHMDAAAAQR--LLARLGSPLSVVRYED ::: * *: *** : :* .: : : MUL_0453|M.ulcerans_Agy99 --VAVAALAGTDRGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRS MMAR_4951|M.marinum_M --VAVAALAGTDRGHAVAFVRRVLGPLAANDEGTYRIAATLAVYLEENRS Mb1464|M.bovis_AF2122/97 --VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRS Rv1429|M.tuberculosis_H37Rv --VAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRS Mflv_4621|M.gilvum_PYR-GCK PGVALASMLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVFLRAGSS TH_2938|M.thermoresistible__bu PGLSAAALLTGDLAEARTWVQEVLGPLSADTKNDARLRETLGVFLRHGSS MLBr_01052|M.leprae_Br4923 --VQLVSLITQNPEDAKEFITSTLGDFES---ASPALQQTLLTFINEQCN MAB_2657c|M.abscessus_ATCC_199 --VHLMDLLSADPASADQFVTDVLGEFQS---ASPVLHQTVLTYVEEALN : : : :: .** : : *: :: . MUL_0453|M.ulcerans_Agy99 PAKAAQRLGVHP-------RAPALLISRLVSWG--IVD------------ MMAR_4951|M.marinum_M PAKAAQRLGVHPNTVSYRVHQAEELLGRTIDIG--ALDLSVALALLPAMR Mb1464|M.bovis_AF2122/97 YVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMA Rv1429|M.tuberculosis_H37Rv YVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMA Mflv_4621|M.gilvum_PYR-GCK FKAAANELQIHANTVKYRVNRALERRGRPIAA--ERLDVEVALLMCYWLG TH_2938|M.thermoresistible__bu YTAAADELNLHFNTVKYRVQRAVERRGRPIVP--DRLDVELALLICQWFG MLBr_01052|M.leprae_Br4923 ASRAAKRLFTHRNTLLRRIESAEKLLPRPLDHT--SVHIAVALEALQWRG MAB_2657c|M.abscessus_ATCC_199 RTSTAERLYTHRNTIDRRLARVDELLPKPFARN--PIEVAAALTLLRVRA :*. : * : . . MUL_0453|M.ulcerans_Agy99 ------------------ MMAR_4951|M.marinum_M AMTQRSGGEL-------- Mb1464|M.bovis_AF2122/97 PAVLRAKQ---------- Rv1429|M.tuberculosis_H37Rv PAVLRAKQ---------- Mflv_4621|M.gilvum_PYR-GCK EVALNPTQALGRS----- TH_2938|M.thermoresistible__bu AAVLRPQR---------- MLBr_01052|M.leprae_Br4923 DQTNTSGPRAGRNDGVPA MAB_2657c|M.abscessus_ATCC_199 GR----------------