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ARQHPSPRVRELIREGARIALNPTQEWIDQLDRATFAANPAIANDPVLAKVVRRASRAHLVHWATANLRD PGAPVPAHLGPEPLTMARDLVRRGRDVLALDIYRVGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSIN EYVAATLEAIATHMQLERDELTRSTHAERLEVVDLILEGAPVTQERAEARLGYRLGLTHTAAVIWSDDLD GDHGYLDQAAEAFSHVVESTQQLIVVASAATRWVWLADALALDVPEVQKALLNLSKARVAIGTSSAGIEG FRRSHLEALTAQRTLARLKSHQQVAFFADVQLVSLITQNPEDAKEFITSTLGDFESASPALQQTLLTFIN EQCNASRAAKRLFTHRNTLLRRIESAEKLLPRPLDHTSVHIAVALEALQWRGDQTNTSGPRAGRNDGVPA *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01052 | - | - | 100% (421) | hypothetical protein MLBr_01052 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1226c | - | 1e-169 | 69.83% (421) | hypothetical protein Mb1226c |
| M. gilvum PYR-GCK | Mflv_4621 | - | 6e-15 | 24.86% (346) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1194c | - | 1e-169 | 69.83% (421) | hypothetical protein Rv1194c |
| M. abscessus ATCC 19977 | MAB_2657c | - | 2e-70 | 36.59% (399) | hypothetical protein MAB_2657c |
| M. marinum M | MMAR_4242 | - | 1e-169 | 70.57% (418) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1456 | - | 3e-07 | 29.79% (141) | hypothetical protein MSMEG_1456 |
| M. thermoresistible (build 8) | TH_3143 | - | 6e-21 | 26.19% (336) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0944 | - | 1e-168 | 69.86% (418) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4621|M.gilvum_PYR-GCK --------------------------------------------------
TH_3143|M.thermoresistible__bu --------------------------------------------------
MMAR_4242|M.marinum_M --------------------------------------------------
MUL_0944|M.ulcerans_Agy99 --------------------------------------------------
Mb1226c|M.bovis_AF2122/97 --------------------------------------------------
Rv1194c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01052|M.leprae_Br4923 --------------------------------------------------
MAB_2657c|M.abscessus_ATCC_199 -----------------------------------------MNEGSERVH
MSMEG_1456|M.smegmatis_MC2_155 MTAPPIDSGRMTVRGLLDESLMAGSRIVAGEDLLDEELTWVLPLNEVLSQ
Mflv_4621|M.gilvum_PYR-GCK ------MLDSSEVQDTPGHAVHHLFRDLGDLVRELPESIHGLLIEQV---
TH_3143|M.thermoresistible__bu ------VVVSGYNADDISSTVALIVDRLLENSGEDVERIQRRILADI---
MMAR_4242|M.marinum_M -------MPWQRPSSRIRELIREGARRALNAGPEWIEELDRETVSAN---
MUL_0944|M.ulcerans_Agy99 -------MPWQRPSSRIRELIREGARRALNAGPEWIEELDRETVSAN---
Mb1226c|M.bovis_AF2122/97 -------MAWQQPSPRIRELIREGARIALNPSPEWIEELDRATIAAN---
Rv1194c|M.tuberculosis_H37Rv -------MAWQQPSPRIRELIREGARIALNPSPEWIEELDRATIAAN---
MLBr_01052|M.leprae_Br4923 -------MARQHPSPRVRELIREGARIALNPTQEWIDQLDRATFAAN---
MAB_2657c|M.abscessus_ATCC_199 TQSMTPDQLWPDASEPVRRLIRELAEKMLARSGEVAGDLTAASLEDPRY-
MSMEG_1456|M.smegmatis_MC2_155 HDRLDAVAVYARPESLTARASTLSALAARGATTLLVDGVAPPDLGGLPAG
: .
Mflv_4621|M.gilvum_PYR-GCK ----------------AELAADQQLKELLSDTVAANVDTWFSV-VRHSIP
TH_3143|M.thermoresistible__bu ----------------DELRSDPRLVELLRSSVAGNVETVLTV-IRYGID
MMAR_4242|M.marinum_M ----------------PTIANDPVLAKVVKRANRANLVHWAAANVRHPGA
MUL_0944|M.ulcerans_Agy99 ----------------PTIANDPVLAKVVKRVNRANLVHWAAANVRHPGA
Mb1226c|M.bovis_AF2122/97 ----------------PAIANDPVLAKVVQTANRANLVYWAAANLRDPGA
Rv1194c|M.tuberculosis_H37Rv ----------------PAIANDPVLAKVVQTANRANLVYWAAANLRDPGA
MLBr_01052|M.leprae_Br4923 ----------------PAIANDPVLAKVVRRASRAHLVHWATANLRDPGA
MAB_2657c|M.abscessus_ATCC_199 ----------------RTIADDPVIAEVDARLTVSNLKHWLTSNISEPGH
MSMEG_1456|M.smegmatis_MC2_155 LVVVELGIPVGFAALNRLLAERALSQEVHVMRYSTHVHATLAGLFHRGAG
: :: :: : .
Mflv_4621|M.gilvum_PYR-GCK FDRMESPTAALEHARRMAQREVPVNALLRAYRLGHQYGLNLIIAGLRSAD
TH_3143|M.thermoresistible__bu LDRVEPPTAALEYARRAAQHGIALSALIRAYRLGQQEMLERILREVRETE
MMAR_4242|M.marinum_M PVPANLGGEPLRMARDLVRRGLETLTLD-IYRIGQYIAWRLWINIAFDLT
MUL_0944|M.ulcerans_Agy99 PVPANLGGEPLRMARDLVRRGLEALTLD-IYRIGQYIAWRLWINIAFDLT
Mb1226c|M.bovis_AF2122/97 RVPANLGTEPLRMARDLVRRGLDTVAFN-IYRTGEHIGWRFWMGIAFELT
Rv1194c|M.tuberculosis_H37Rv RVPANLGTEPLRMARDLVRRGLDTVAFN-IYRTGEHIGWRFWMGIAFELT
MLBr_01052|M.leprae_Br4923 PVPAHLGPEPLTMARDLVRRGRDVLALD-IYRVGQYTAWRRWMEIAFTLT
MAB_2657c|M.abscessus_ATCC_199 RVRPATGSAMRTYARDVVLRGLTTDDIQ-SWRAVQRVGWKWWLAACFQVT
MSMEG_1456|M.smegmatis_MC2_155 LQILVREVSNLARNPAVALDARGHVVAHHGLPPEAVAALADSVSRMLAAD
. :
Mflv_4621|M.gilvum_PYR-GCK LPPEEK----------------------LALIEHITRVSFRYIDWMSEQV
TH_3143|M.thermoresistible__bu LDPDLR----------------------LSVYERISSTSFAYIDWISQQV
MMAR_4242|M.marinum_M SDPQEL----------------------RELLDVSAKSVNEFIEATLAGI
MUL_0944|M.ulcerans_Agy99 SDPQEL----------------------HELLDVSAKSVNEFIEATLAGI
Mb1226c|M.bovis_AF2122/97 SDPQEL----------------------RELLDVSARSVNDFIEATLTGI
Rv1194c|M.tuberculosis_H37Rv SDPQEL----------------------RELLDVSARSVNDFIEATLTGI
MLBr_01052|M.leprae_Br4923 SDPQEL----------------------REILNVSAQSINEYVAATLEAI
MAB_2657c|M.abscessus_ATCC_199 DDKEQL----------------------CELIEVTSNSLTTFVDDSIAEL
MSMEG_1456|M.smegmatis_MC2_155 LPASERRHDGHDTRTQQVTGPEDSRWTCVASAIRLGKSFEGWVAVLVPTL
. :: :
Mflv_4621|M.gilvum_PYR-GCK LETYQTERAEWDERRRSLRAQAIRDILNGRD-----VDLTEASSAMRYFL
TH_3143|M.thermoresistible__bu SDTYDTERERWLEHRNNIRAVRVREILDSDEP----IDIDTASAALGYPL
MMAR_4242|M.marinum_M AAQVQLEHDELTRGNHADRLEVVGHLLEGAP-----ISRERAETRLGYSL
MUL_0944|M.ulcerans_Agy99 AAQVQLEHDELTRGNHADRLEVVGHLLEGAP-----ISRERAETRLGYSL
Mb1226c|M.bovis_AF2122/97 AAQVQSEHDELTRSTHAERLEVVGLILDGAP-----ISPERAEAKLGYPL
Rv1194c|M.tuberculosis_H37Rv AAQVQSEHDELTRSTHAERLEVVGLILDGAP-----ISPERAEAKLGYPL
MLBr_01052|M.leprae_Br4923 ATHMQLERDELTRSTHAERLEVVDLILEGAP-----VTQERAEARLGYRL
MAB_2657c|M.abscessus_ATCC_199 AEHVRRVREELAGGSQLQRYATVELLLQGAD-----IAPARAEAQLGYAL
MSMEG_1456|M.smegmatis_MC2_155 APDHADGPSKHDLARHEVLTEQATAIIGSEMLRQRSVDEAEERARGDFVQ
. . :: . : : :
Mflv_4621|M.gilvum_PYR-GCK GATHVALMVWLDRDAGADTDEFIAMERFMQHAVSATGAKQS---------
TH_3143|M.thermoresistible__bu RGRHLALVLWMTR-SDLPGGELLRLERFARAVAEAFQLRNTP--------
MMAR_4242|M.marinum_M IRAHTAAIIWSDD----FDGDHSNLDRAADAFCHAVGSSQD---------
MUL_0944|M.ulcerans_Agy99 IRAHTAAIIWSDD----FDGDHSNLDRAADAFCHAVGSSQD---------
Mb1226c|M.bovis_AF2122/97 SRAHTAAIIWSDE----LDGDHSYLDRAADLFCHAVGSTRP---------
Rv1194c|M.tuberculosis_H37Rv SRAHTAAIIWSDE----LDGDHSYLDRAADLFCHAVGSTRP---------
MLBr_01052|M.leprae_Br4923 GLTHTAAVIWSDD----LDGDHGYLDQAAEAFSHVVESTQQ---------
MAB_2657c|M.abscessus_ATCC_199 TGSHIGAVVWVDS----EK-EIAALERASEQVMRACGADRR---------
MSMEG_1456|M.smegmatis_MC2_155 ALVHGSFSSEHDMRARAEHHDIELDARFGVFVAPGVLPRGPDSPTTPMVR
* . : :
Mflv_4621|M.gilvum_PYR-GCK ----VYFSIDRLVGCAWMTV-HRPSDYLSQLR------------------
TH_3143|M.thermoresistible__bu ----LFVAEDTVSGWAWLAINHVVTEPVRTIR------------------
MMAR_4242|M.marinum_M ----LTVVANAATRWVWLAEATNLD--IDTIE------------------
MUL_0944|M.ulcerans_Agy99 ----LTVVANAATRWVWLAEATNLD--IDTIE------------------
Mb1226c|M.bovis_AF2122/97 ----LTVVAGAASRWAWVTDADGLD--IDTVQ------------------
Rv1194c|M.tuberculosis_H37Rv ----LTVVAGAASRWAWVTDADGLD--IDTVQ------------------
MLBr_01052|M.leprae_Br4923 ----LIVVASAATRWVWLADALALD--VPEVQ------------------
MAB_2657c|M.abscessus_ATCC_199 ----LTVVAGTVALWLWIPAKTTPT--VAVLM------------------
MSMEG_1456|M.smegmatis_MC2_155 LARYAAGVAAHPSVHAYVTVIGDVLVVVRTLRGEDAAAMRSEMAEYAEAM
::. : :
Mflv_4621|M.gilvum_PYR-GCK --DFVRAQPDGPRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHR
TH_3143|M.thermoresistible__bu --ELAETADNGVHVALGTVDDGLEGFRRSHRRARDARKVAAAS--AIPPR
MMAR_4242|M.marinum_M --QAVDNAS-DARIAIGTKASGIEGFRRSHLEALTTQRTLARLK----SD
MUL_0944|M.ulcerans_Agy99 --QAVDNAS-DARIAIGTKASGIEGFRRSHLEALTTQRTLARLK----SD
Mb1226c|M.bovis_AF2122/97 --AAVDNAP-GARIAIGTTANGVEGFRRSHLEALITQRTLSRLR----ST
Rv1194c|M.tuberculosis_H37Rv --AAVDNAP-GARIAIGTTANGVEGFRRSHLEALITQRTLSRLR----ST
MLBr_01052|M.leprae_Br4923 --KALLNLS-KARVAIGTSSAGIEGFRRSHLEALTAQRTLARLK----SH
MAB_2657c|M.abscessus_ATCC_199 --DSLGRRS-GVRVALGRAATGMAGFRRTHMDAAAAQRLLARLG----SP
MSMEG_1456|M.smegmatis_MC2_155 SGELQRRRGLPAPVAYGRPALGAGEVRESYREARVALGIARRLHR--TGA
:: * * .*.:: * :
Mflv_4621|M.gilvum_PYR-GCK IVAARDPGVALASMLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVF
TH_3143|M.thermoresistible__bu ITAADDYGISVSALLTENLADTRRWVLDTLGPLASDTANDARLRETLLVF
MMAR_4242|M.marinum_M QRVAFFSDVQIVALITQNPQAADEFITSTLGELESAAP---ELQATLLMF
MUL_0944|M.ulcerans_Agy99 QRVAFFSDVQIVALITQNTQAANEFITSTLGELESAAP---ELQATLLMF
Mb1226c|M.bovis_AF2122/97 QRVAFFADVKMVALISQNPDAASEFITSTLGDLESASP---DLQTALLTF
Rv1194c|M.tuberculosis_H37Rv QRVAFFADVKMVALISQNPDAASEFITSTLGDLESASP---DLQTALLTF
MLBr_01052|M.leprae_Br4923 QQVAFFADVQLVSLITQNPEDAKEFITSTLGDFESASP---ALQQTLLTF
MAB_2657c|M.abscessus_ATCC_199 LSVVRYEDVHLMDLLSADPASADQFVTDVLGEFQSASP---VLHQTVLTY
MSMEG_1456|M.smegmatis_MC2_155 TSYQQLRGFTVLAQVAETE-DSRQLVRDVLGPLRSSPD----LLETLEAY
.. : : . : ..** : . . * :: :
Mflv_4621|M.gilvum_PYR-GCK LRAGSSFKAAANELQIHANTVKYRVNRALERRGRPIAAERLDVEVALLMC
TH_3143|M.thermoresistible__bu LHVGSSYTAAAERLLLHPNSVRYRVNRAVERRARPIGEDRLEVELALLAC
MMAR_4242|M.marinum_M INEQCNASRAAKRLYTHRNTLLRRIEAAQRLLPRPLAHTSVHVAVALEAL
MUL_0944|M.ulcerans_Agy99 INEQCNASRAAKRLYTHRNTLLRRIEAAQRLLPRPLAHTSVHVAVALEAL
Mb1226c|M.bovis_AF2122/97 INEQCNASRAAKRLHTHRNTFLRRLESAQRLLPRPLDHTSVHVAVALEAL
Rv1194c|M.tuberculosis_H37Rv INEQCNASRAAKRLHTHRNTFLRRLESAQRLLPRPLDHTSVHVAVALEAL
MLBr_01052|M.leprae_Br4923 INEQCNASRAAKRLFTHRNTLLRRIESAEKLLPRPLDHTSVHIAVALEAL
MAB_2657c|M.abscessus_ATCC_199 VEEALNRTSTAERLYTHRNTIDRRLARVDELLPKPFARNPIEVAAALTLL
MSMEG_1456|M.smegmatis_MC2_155 LSEGGNINATARTLNVHRNTMLAKLDRISRMLGMDVRDPEHQFTVWLAIR
: . . :*. * * *:. :: . . .. *
Mflv_4621|M.gilvum_PYR-GCK YWLGEVALNPTQALGRS-----
TH_3143|M.thermoresistible__bu RHFQQAVLQPAD----------
MMAR_4242|M.marinum_M QWRGDNIAKLPTPTSQDDEVPA
MUL_0944|M.ulcerans_Agy99 QWRGDNIAKLPTPTSQDDEVPA
Mb1226c|M.bovis_AF2122/97 QWRGNKAHALSSPGRRSNSVPA
Rv1194c|M.tuberculosis_H37Rv QWRGNKAHALSSPGRRSNSVPA
MLBr_01052|M.leprae_Br4923 QWRGDQTNTSGPRAGRNDGVPA
MAB_2657c|M.abscessus_ATCC_199 RVRAGR----------------
MSMEG_1456|M.smegmatis_MC2_155 LDLLDEVHSAVEREASFR----